Drugs / triiodothyronine
triiodothyronine
Trials 12
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT00289367 | Feb → Aug 2006 | atrial fibrillation | Northwell Health | Completed | No outcome recorded |
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT05384847 | Dec 2022 → May 2026 overdue | heart failure | Emory University | Active not recruiting | No outcome recorded |
| Phase 23 trials · 1 met primary | ||||||
| Phase 2 | NCT05270798 | May 2022 → Aug 2023 | euthyroid sick syndrome, infectious disease with sepsis | Cantonal Hospital Zenica | Completed | Mixed |
| Phase 2 | NCT04348513 | May 2020 → Apr 2021 | COVID-19 | Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. | Terminated | No outcome recorded Stop: Enrollment |
| Phase 2 | NCT01780584 | Apr → Sep 2010 | euthyroid sick syndrome | National Cardiovascular Center Harapan Kita Hospital Indonesia | Completed | Met primary |
| Phase 32 trials · 1 met primary | ||||||
| Phase 3 | NCT02521168 | Jul 2013 → Oct 2014 | postoperative ventricular dysfunction | National Cardiovascular Center Harapan Kita Hospital Indonesia | Completed | No outcome recorded |
| Phase 3 | NCT00158990 | Oct 2002 → Jul 2007 | bipolar disorder, major depressive disorder | Hadassah Medical Organization | Completed | Met primary |
| Phase 43 trials · 1 missed | ||||||
| Phase 4 | NCT00360074 | Feb 2004 → Apr 2007 | hyperlipidemia, hypopituitarism, thyroid gland disorder | University Hospital Freiburg | Completed | No outcome recorded |
| Phase 4 | NCT00296686 | Sep 2001 → Aug 2006 | major depressive disorder | New York State Psychiatric Institute | Terminated | No outcome recorded Stop: Business |
| Phase 4 | NCT00208702 | Sep 1996 → Jul 2003 | major depressive disorder | Emory University | Completed | Missed primary |
| Phase not applicable2 trials | ||||||
| — | NCT01360177 | Jul 2010 → Dec 2013 | breast cancer | Stanford University | Withdrawn | No outcome recorded |
| — | NCT00421369 | Sep 2007 → Aug 2011 | major depressive disorder | Hadassah Medical Organization | Completed | No outcome recorded |
| Comparator or background therapy3 trials | ||||||
| Phase 3 | NCT00027417 Comparator | Apr 2001 → Aug 2007 | congenital heart disease | Michael Portman | Completed | No outcome recorded |
| Phase 4 | NCT00531713 Comparator | Apr 2003 → Mar 2007 | depressive disorder | Copenhagen University Hospital at Herlev | Completed | No outcome recorded |
| — | NCT00715572 Comparator | Mar 2002 → Feb 2004 | hypothyroidism | I.M. Sechenov First Moscow State Medical University | Completed | No outcome recorded |
Evidence & citations 4 cited values
Every value below carries the sentence it was read from. 18 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | triiodothyronine | “acute administration of triiodothyronine (T3) in critically ill COVID-19 infected patients requiring mechanical respiratory support or Extra Corporeal Membrane Oxygenation (ECMO).” PMID 32586399 ↗ Jun 202015“Thyroid hormone replacement for central hypothyroidism: a randomized controlled trial comparing two doses of thyroxine (T4) with a combination of T4 and triiodothyronine.” PMID 17711927 ↗ Aug 2007 “Sequential Tranylcypromine (TC), TC + Dextroamphetamine and TC + Triiodothyronine for Refractory Depression” NCT00296686 ↗ “Oral Triiodothyronine Normalizes T3 Levels After Surgery For Pediatric Congenital Heart Disease” NCT01780584 ↗ “transient triiodothyronine (thyroid hormone T3) administration in patients with HF” NCT05384847 ↗ |
| Known as | liothyronine sodium | “bolus administration of Liothyronine Sodium/Triiodothyronine (Triostat) immediately prior to CPB institution and after removal of aortic cross clamp, followed by repeated boluses” NCT00027417 ↗1“liothyronine sodium (triiodothyronine)” PMID 17548749 ↗ Jun 2007 |
| Known as | Triostat | “bolus administration of Liothyronine Sodium/Triiodothyronine (Triostat) immediately prior to CPB institution and after removal of aortic cross clamp, followed by repeated boluses” NCT00027417 ↗ |
| Route | Intravenous | “Patients received intravenous T3 as Triostat” PMID 20837917 ↗ Sep 2010 |