Drugs / veldoreotide
last change Dec 2022 re-read 2 minutes ago

veldoreotide

also known as DG3173 · COR-005 · PTR 3173 · Somatoprim · VELD · Veldoreotida

Protein / enzyme biologic targets SSTR2, SSTR4, SSTR5 via activation

Developed for
acromegaly · breast cancer
Investigated by
Aspireo Pharmaceuticals Limited · DeveloGen AG, Germany

Trials 5 · a red edge is where a trial was stopped

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT02217839 Apr 2012 → Jan 2013 Aspireo Pharmaceuticals Limited Completed No outcome recorded
Phase 1 NCT02217488 May → Sep 2008 Aspireo Pharmaceuticals Limited Completed No outcome recorded
Phase 1 NCT02217826 ? → Apr 2014 Aspireo Pharmaceuticals Limited Completed No outcome recorded
Phase 22 trials
Phase 2 NCT02217800 Nov 2013 → Mar 2014 acromegaly Aspireo Pharmaceuticals Limited Completed No outcome recorded
Phase 2 NCT02235987 Oct → Dec 2012 acromegaly Aspireo Pharmaceuticals Limited Completed No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04138342 Comparator Sep 2019 → Jun 2021 breast cancer, skin cancer Al-Azhar University Unknown No outcome recorded

Evidence & citations 13 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as veldoreotide ClinicalTrials.gov intervention name — accepted as the source's own label NCT04138342
Known as COR-005 ChEMBL registry synonym — accepted as the source's own label CHEMBL3989911
Known as DG3173 “Interventions: octreotide and DG3173.” NCT02235987
4

NCT02217800

NCT02217488

NCT02217839

NCT02217826

Known as PTR 3173 ChEMBL registry synonym — accepted as the source's own label CHEMBL3989911
Known as Somatoprim “three different doses of Somatoprim (DG3173)” NCT02217826
Known as VELD “somatostatin analog (veldoreotide) (VELD) may be suitable for delivering anti-cancer drugs to target and bioimaging the cancer cells.” NCT04138342
Known as Veldoreotida ChEMBL registry synonym — accepted as the source's own label CHEMBL3989911
Action Activate “VELD as SSTR agonist with anti-cancer activity” NCT04138342
3

“Somatostatin receptor 5 agonist” CHEMBL3989911

“Somatostatin receptor 2 agonist” CHEMBL3989911

“Somatostatin receptor 4 agonist” CHEMBL3989911

Modality Protein / enzyme biologic CHEMBL3989911
Route Subcutaneous “via single dose subcutaneous injection” NCT02217488
Target SSTR2 “Somatostatin receptor 2 agonist” CHEMBL3989911
Target SSTR4 “Somatostatin receptor 4 agonist” CHEMBL3989911
Target SSTR5 “Somatostatin receptor 5 agonist” CHEMBL3989911