drugset / Trial / NCT02217800

The Effect of Subcutaneous Infusions of 3 Doses of DG3173 on Growth Hormone Levels in Untreated Acromegalics

NCT02217800

Phase 2 Completed 8 enrolled Aspireo Pharmaceuticals Limited
NaSingle-groupOpen-labelTreatment

Summary

This study is designed to assess the effect of the different continuous s.c. infusion treatments on the human growth hormone (hGH) levels in untreated acromegalic patients in comparison to a standard dose of octreotide. In addition, the pharmacokinetic profile and the safety and tolerability of DG3173 after continuous s.c. infusion will be evaluated.

Timeline

Start
2013-11
Primary completion
2014-03
Completion
2016-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Octreotide Peptide 300 ug Subcutaneous
Subject veldoreotide Protein / enzyme biologic 920 ug Subcutaneous
Subject veldoreotide Protein / enzyme biologic 2760 ug Subcutaneous
Subject veldoreotide Protein / enzyme biologic 5520 ug Subcutaneous

Indications