Drugs / Hyaluronan
Hyaluronan
also known as
Gel-One · HYAJOINT Plus · Hyaluronan acid : Neovisc · hyaluronic acid · Monovisc · sodium hyaluronate
Trials 6
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 01 trial | ||||||
| Phase 0 | NCT03429140 | Apr 2017 → Jun 2019 | — | Cale Jacobs, PhD | Completed | No outcome recorded |
| Phase 21 trial · 1 met primary | ||||||
| Phase 2 | NCT04315103 | Aug 2018 → Jan 2019 | osteoarthritis, knee | Kaohsiung Veterans General Hospital. | Completed | Met primary |
| Phase 2/32 trials | ||||||
| Phase 2/3 | NCT03889925 | Mar 2019 → Oct 2022 | osteoarthritis, knee | Andrews Research & Education Foundation | Completed | No outcome recorded |
| Phase 2/3 | NCT00591916 | Jan 2006 → Nov 2010 | — | The University of Texas Medical Branch, Galveston | Withdrawn | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT02086474 | May 2014 → Aug 2017 | osteoarthritis, hip | Laval University | Completed | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT02536807 | Aug 2014 → May 2016 | — | Malmö University | Completed | No outcome recorded |
| Comparator or background therapy8 trials | ||||||
| Phase 0 | NCT01464528 Comparator | Nov 2011 → Mar 2012 | adhesions of uterus | Hadassah Medical Organization | Unknown | No outcome recorded |
| Phase 1/2 | NCT01088191 Comparator | Mar 2009 → Nov 2013 | osteoarthritis | Mesoblast, Inc. | Completed | No outcome recorded |
| Phase 1/2 | NCT00225095 Background | Sep 2005 → Apr 2008 | — | Mesoblast, Ltd. | Completed | No outcome recorded |
| Phase 2 | NCT01453738 Background | Nov 2011 → Nov 2014 | osteoarthritis, knee | Stempeutics Research Pvt Ltd | Completed | No outcome recorded |
| Phase 2 | NCT01448434 Background | Sep 2011 → Sep 2013 | osteoarthritis, knee | Stempeutics Research Pvt Ltd | Completed | No outcome recorded |
| Phase 4 | NCT05492851 Comparator | Aug 2022 → Jan 2023 | osteoarthritis, knee | Ohio State University | Terminated | No outcome recorded Stop: Enrollment |
| — | NCT06078449 Background | Nov 2023 → Mar 2024 | osteoarthritis, knee | Badr University | Unknown | No outcome recorded |
| — | NCT01469507 Comparator | — | osteoarthritis, knee | Pierre Fabre Laboratories | Withdrawn | No outcome recorded |
Press releases naming this drug 1 release
| Date | Issuer | Release |
|---|---|---|
| 2019-07-01 | Teva Branded Pharmaceutical Products R&D, Inc. | Teva Announces Launch of 1% Sodium Hyaluronate in the United States tevapharm.com ↗ |
Evidence & citations 9 cited values
Every value below carries the sentence it was read from. 16 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Hyaluronan | “Generic Name: Hyaluronan The Monovisc™ device is a proprietary high molecular weight hyaluronic acid (HA) viscosupplementation intended for the treatment of pain in patients...” NCT05492851 ↗13“a single crosslinked hyaluronan (HYAJOINT Plus) and a single PRP versus a single PRP in patients with knee OA” PMID 33420185 ↗ Jan 2021 “Single intraarticular dose of allogeneic MSCs suspended in 2ml Plasmalyte followed by 2ml of Hyaluronan” NCT01448434 ↗ “Single intraarticular dose of 2ml Plasmalyte followed by 2ml Hyaluronan” NCT01453738 ↗ “an injection of Gel-One® (hyaluronan, 3 mL) 1-2 weeks after ACL surgery” NCT03429140 ↗ |
| Known as | Gel-One | “an injection of Gel-One® (hyaluronan, 3 mL) 1-2 weeks after ACL surgery” NCT03429140 ↗ |
| Known as | HYAJOINT Plus | “a single crosslinked hyaluronan (HYAJOINT Plus) and a single PRP versus a single PRP in patients with knee OA” PMID 33420185 ↗ Jan 2021 |
| Known as | Hyaluronan acid : Neovisc | “Hyaluronan acid : Neovisc®” NCT02086474 ↗ |
| Known as | hyaluronic acid | “the control group, a sodium hyaluronate (hyaluronic acid/hyaluronan) vehicle control.” PMID 24430407 ↗ Jan 2014 |
| Known as | Monovisc | “Generic Name: Hyaluronan The Monovisc™ device is a proprietary high molecular weight hyaluronic acid (HA) viscosupplementation intended for the treatment of pain in patients...” NCT05492851 ↗ |
| Known as | sodium hyaluronate | “the control group, a sodium hyaluronate (hyaluronic acid/hyaluronan) vehicle control.” PMID 24430407 ↗ Jan 2014 |
| Modality | Other / unclassified | “single crosslinked hyaluronan” NCT04315103 ↗ |
| Route | Other | “MSB-CAR001 plus Hyaluronan at one of two doses or Hyaluronan alone will be injected into the knee joint.” NCT01088191 ↗ |