Drugs / Ponezumab
last change Sep 2015 re-read 3 minutes ago

Ponezumab

also known as PF-04360365 · RN-1219

Monoclonal antibody targets APP

Developed for
Alzheimer disease · cerebral amyloid angiopathy
Investigated by
Pfizer

Trials 8

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 15 trials
Phase 1 NCT01125631 May 2010 → Aug 2011 Alzheimer disease Pfizer Completed No outcome recorded
Phase 1 NCT01005862 Mar 2010 → Sep 2012 Alzheimer disease Pfizer Completed No outcome recorded
Phase 1 NCT00733642 Aug 2008 → Jul 2009 Alzheimer disease Pfizer Completed No outcome recorded
Phase 1 NCT00607308 Feb 2008 → Oct 2010 Alzheimer disease Pfizer Completed No outcome recorded
Phase 1 NCT00455000 Mar 2007 → Sep 2009 Alzheimer disease Pfizer Completed No outcome recorded
Phase 23 trials
Phase 2 NCT01821118 Jun 2013 → Sep 2015 cerebral amyloid angiopathy Pfizer Completed No outcome recorded
Phase 2 NCT00945672 Aug 2009 → Jun 2011 Alzheimer disease Pfizer Completed No outcome recorded
Phase 2 NCT00722046 Dec 2008 → Aug 2011 Alzheimer disease Pfizer Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 9 sources stand behind the page.

FieldValueCited text
Known as Ponezumab ClinicalTrials.gov intervention name — accepted as the source's own label NCT01821118 ↗
Known as PF-04360365 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01125631 ↗
6

NCT00945672 ↗

NCT00733642 ↗

NCT00455000 ↗

NCT00722046 ↗

NCT01005862 ↗

NCT00607308 ↗

Known as RN-1219 ChEMBL registry synonym — accepted as the source's own label CHEMBL1743058 ↗
Modality Monoclonal antibody “Monoclonal antibody” NCT00455000 ↗
Route Intravenous “a single IV dose of PF-04360365” NCT00455000 ↗
Target APP “Amyloid-beta A4 protein binding agent” CHEMBL1743058 ↗