Effect of PF-04360365 On ABETA In Patients With Alzheimer's Disease And Healthy Volunteers

Summary

The primary goal of this study is to evaluate the effect of PF-04360365 on the clearance of ABETA from the CSF (cerebrospinal fluid) in patients with mild Alzheimer's disease and healthy volunteers. Additionally, the study will assess the pharmacokinetics of PF-04360365, pharmacokinetic and pharmacodynamic relationships in plasma and CSF and the safety and tolerability of single doses of PF-04360365 administered to patients with Alzheimer's disease and healthy volunteers.

Timeline

Start

2010-03

Primary completion

2012-09

Completion

2012-09

Drugs

Indications