Drugs / VX-150
last change Apr 2025 re-read 2 minutes ago

VX-150

Developed for
neuropathy, small fiber · osteoarthritis
Investigated by
Vertex Pharmaceuticals Incorporated

Trials 6 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT06420765 May 2024 → Mar 2025 Vertex Pharmaceuticals Incorporated Completed No outcome recorded
Phase 1 NCT05418712 Jun → Sep 2022 Vertex Pharmaceuticals Incorporated Completed No outcome recorded
Phase 24 trials
Phase 2 NCT03764072 Dec 2018 → Jan 2019 Vertex Pharmaceuticals Incorporated Completed No outcome recorded
Phase 2 NCT03304522 Sep 2017 → Oct 2018 neuropathy, small fiber Vertex Pharmaceuticals Incorporated Completed No outcome recorded
Phase 2 NCT03206749 Jun → Dec 2017 Vertex Pharmaceuticals Incorporated Completed No outcome recorded
Phase 2 NCT02660424 Dec 2015 → Aug 2016 osteoarthritis Vertex Pharmaceuticals Incorporated Completed No outcome recorded

Press releases naming this drug 2 releases

DateIssuerRelease
2018-12-18 Vertex Pharmaceuticals Incorporated Vertex Announces Positive Phase 2 Data in Third Proof-of-Concept Study with the NaV1.8 Inhibitor VX-150 vrtx.com
2018-02-14 Vertex Pharmaceuticals Incorporated Vertex Announces Treatment with the NaV1.8 Inhibitor VX-150 Showed Significant Relief of Acute Pain in Phase 2 Study vrtx.com

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as VX-150 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06420765
5

NCT03206749

NCT02660424

NCT03304522

NCT05418712

NCT03764072

Action Inhibit “NaV1.8 inhibition” NCT06420765
Route Oral “1250 milligrams (mg) once daily (qd) orally” NCT03304522