bone marrow mononuclear cells
Trials 10
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 12 trials | ||||||
| Phase 1 | NCT05517317 | Jan 2015 → May 2022 | biliary atresia | Vinmec Research Institute of Stem Cell and Gene Technology | Completed | No outcome recorded |
| Phase 1 | NCT02352077 | Jan 2015 → Dec 2021 | spinal cord injury | Chinese Academy of Sciences | Unknown | No outcome recorded |
| Phase 1/24 trials | ||||||
| Phase 1/2 | NCT02648386 | Jan 2016 → Dec 2020 | erectile dysfunction, rectal cancer | Chinese Academy of Sciences | Unknown | No outcome recorded |
| Phase 1/2 | NCT02688062 | Jan 2016 → Dec 2021 | spinal cord injury | Chinese Academy of Sciences | Unknown | No outcome recorded |
| Phase 1/2 | NCT02237547 | Sep 2014 → Jan 2019 | spinal cord injury | Translational Biosciences | Withdrawn | No outcome recorded Stop: Enrollment |
| Phase 1/2 | NCT01480414 | Sep 2010 → Apr 2012 | ulcer of lower limbs | Royan Institute | Completed | No outcome recorded |
| Phase 23 trials · 1 missed | ||||||
| Phase 2 | NCT05307536 | Dec 2021 → Jun 2023 | autism spectrum disorder | Vinmec Research Institute of Stem Cell and Gene Technology | Completed | No outcome recorded |
| Phase 2 | NCT02178657 | Apr 2015 → Oct 2021 | ischemic stroke | Andalusian Initiative for Advanced Therapies | Completed | Missed primary |
| Phase 2 | NCT00383630 | Sep 2007 → Dec 2008 | congestive heart failure | Columbia University | Terminated | No outcome recorded Stop: Enrollment |
| Phase not applicable1 trial | ||||||
| — | NCT01110252 | May 2009 → Oct 2010 | pulmonary emphysema | UPECLIN HC FM Botucatu Unesp | Completed | No outcome recorded |
| Comparator or background therapy2 trials | ||||||
| Phase 1 | NCT02940418 Comparator | Feb 2017 → Nov 2019 | type 1 diabetes mellitus | Sophia Al-Adwan | Unknown | No outcome recorded |
| Phase 2 | NCT02171949 Comparator | Apr 2015 → Dec 2018 | cirrhosis of liver, hepatitis | Hospital Sao Rafael | Unknown | No outcome recorded |
Evidence & citations 8 cited values
Every value below carries the sentence it was read from. 16 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | bone marrow mononuclear cells | “The purpose of this study is to assess the safety and efficacy of autologous bone marrow mononuclear cells (BMMCs) or allogeneic human umbilical cord-derived mesenchymal stem...” NCT02648386 ↗11“After preparation, separation, counting and labeling (optional) of the mononuclear cells, the patients will receive an intravenous infusion from the pool of Bone Marrow...” PMID 24287082 ↗ Nov 2013 “Intra-arterial bone marrow mononuclear cells (BM-MNCs) transplantation in acute ischemic stroke (IBIS trial): protocol of a phase II, randomized, dose-finding, controlled...” PMID 26044701 ↗ Jun 2015 “intrathecal infusion of autologous bone marrow mononuclear cells (BMMNCs) led to a slight decrease in TGF-β and GDF-15 levels in the CSF of ASD and CP patients, respectively.” PMID 38114596 ↗ Dec 2023 “intramuscular injections of bone marrow mononuclear cells as a cell therapy product.” PMID 27293053 ↗ Jun 2016 “NeuroRegen Scaffold with bone marrow mononuclear cells (BMMCs) transplantation” NCT02688062 ↗ “autologous bone marrow mononuclear cells via the hepatic artery” NCT05517317 ↗ “bone marrow mononuclear cells (BMMCs)” NCT02352077 ↗ |
| Known as | BM-MNC | “Bone marrow mononuclear cell (BM-MNC) transplantation improves recovery in experimental models of ischemic stroke that might be related with miRNA modifications.” PMID 31852749 ↗ Dec 20191“Indeed, recent studies have shown that bone-marrow mononuclear cell (BM-MNC) implantation increases collateral vessel formation in patients with limb ischemia.” NCT01480414 ↗ |
| Known as | BM-MNCs | “intrathecal infusion of autologous bone marrow mononuclear cells (BMMNCs) led to a slight decrease in TGF-β and GDF-15 levels in the CSF of ASD and CP patients, respectively.” PMID 38114596 ↗ Dec 20233“Bone marrow mononuclear cells (BM-MNCs) transplantation in acute ischemic stroke (IBIS trial): protocol of a phase II, randomized, dose-finding, controlled multicenter trial.” PMID 26044701 ↗ Jun 2015 “Pilot clinical trials have shown the safety of intra-arterial bone marrow mononuclear cells (BMMNCs) in stroke.” PMID 36681446 ↗ Feb 2023 “Autologous bone marrow-derived mononuclear cell infusion (BM-MNCs) will be administrated at baseline” NCT05307536 ↗ |
| Known as | BMCs | “bone marrow mononuclear cells (BMCs)” NCT00383630 ↗ |
| Known as | BMMC | “Human Umbilical Cord-derived Mesenchymal Stem Cells (UC-MSC) and Bone Marrow Mononuclear Cells (BMMC) from the patient injected into the spinal fluid intrathecally and injected...” NCT02237547 ↗1“After preparation, separation, counting and labeling (optional) of the mononuclear cells, the patients will receive an intravenous infusion from the pool of Bone Marrow...” PMID 24287082 ↗ Nov 2013 |
| Known as | BMMCs | “The purpose of this study is to assess the safety and efficacy of autologous bone marrow mononuclear cells (BMMCs) or allogeneic human umbilical cord-derived mesenchymal stem...” NCT02648386 ↗2“NeuroRegen Scaffold with bone marrow mononuclear cells (BMMCs) transplantation” NCT02688062 ↗ “bone marrow mononuclear cells (BMMCs)” NCT02352077 ↗ |
| Modality | Cell therapy | “bone marrow mononuclear cells (BMCs)” NCT00383630 ↗ |
| Route | Other | “Intramyocardial injection of bone marrow mononuclear cells” NCT00383630 ↗ |