drugset / Trial / NCT01110252
Safety Study of Cell Therapy to Treat Chronic Obstructive Pulmonary Disease
Completed
4 enrolled
UPECLIN HC FM Botucatu Unesp
Instituto de Molestias Cardiovasculares · collabLaboratório de Genética Humana e Terapia Celular, Unesp - Assis · collab
Non-randomizedSingle-groupOpen-labelTreatment
Summary
The purpose of this study is to determine whether the cell therapy with bone marrow mononuclear cells is safe in the treatment of chronic obstructive pulmonary disease, specifically the pulmonary emphysema.
Timeline
- Start
- 2009-05
- Primary completion
- 2010-10
- Completion
- 2011-11
Publications
- Ribeiro-Paes JT, Stessuk T, Marcelino M, Faria C, Marinelli T, Ribeiro-Paes MJ. A protocol proposition of cell therapy for the treatment of chronic obstructive pulmonary disease. Rev Port Pneumol. 2014 Mar-Apr;20(2):84-91. doi: 10.1016/j.rppneu.2013.06.008. Epub 2013 Nov 26. English, Portuguese.
- Ribeiro-Paes JT, Bilaqui A, Greco OT, Ruiz MA, Marcelino MY, Stessuk T, de Faria CA, Lago MR. Unicentric study of cell therapy in chronic obstructive pulmonary disease/pulmonary emphysema. Int J Chron Obstruct Pulmon Dis. 2011 Jan 1;6:63-71. doi: 10.2147/COPD.S15292.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | bone marrow mononuclear cells | Cell therapy | 30 ml | Intravenous |
| Background | G-CSF | Unknown | 5 ug/kg | Subcutaneous |