Drugs / Vepoloxamer
Vepoloxamer
also known as
MST-188 · poloxamer 188 · Kolliphor p 188 · Lutrol f 68 · Pluracare f 68 · Pluronic f-68 · Pluronic f68lf · Poloxalkol · +4 more
Trials 7
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT02646358 | Jan → Nov 2016 | impaired renal function disease | Mast Therapeutics, Inc. | Completed | No outcome recorded |
| Phase 23 trials | ||||||
| Phase 2 | NCT02596477 | Oct 2015 → Oct 2016 | heart failure | Mast Therapeutics, Inc. | Terminated | No outcome recorded |
| Phase 2 | NCT02093468 | Jun 2014 → Dec 2016 | limb ischemia | Mast Therapeutics, Inc. | Terminated | No outcome recorded |
| Phase 2 | NCT00113009 | Mar 2005 → Jul 2006 | peripheral arterial disease | Valentis | Completed | No outcome recorded |
| Phase 33 trials · 1 missed | ||||||
| Phase 3 | NCT02449616 | Jun 2015 → Sep 2016 | sickle cell disease | Mast Therapeutics, Inc. | Completed | No outcome recorded |
| Phase 3 | NCT01737814 | May 2013 → Feb 2016 | sickle cell disease | Mast Therapeutics, Inc. | Completed | Missed primary |
| Phase 3 | NCT00004408 | Nov 1997 → Nov 1999 | sickle cell disease | Mast Therapeutics, Inc. | Completed | No outcome recorded |
Evidence & citations 15 cited values
Every value below carries the sentence it was read from. 8 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Vepoloxamer | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02596477 ↗ |
| Known as | Kolliphor p 188 | ChEMBL registry synonym — accepted as the source's own label CHEMBL3137355 ↗ |
| Known as | Lutrol f 68 | ChEMBL registry synonym — accepted as the source's own label CHEMBL3137355 ↗ |
| Known as | MST-188 | “MST-188 (Purified Poloxamer 188) Injection in Subjects With Sickle Cell Disease Experiencing Vaso Occlusive Crisis” NCT01737814 ↗ |
| Known as | Pluracare f 68 | ChEMBL registry synonym — accepted as the source's own label CHEMBL3137355 ↗ |
| Known as | Pluronic f-68 | ChEMBL registry synonym — accepted as the source's own label CHEMBL3137355 ↗ |
| Known as | Pluronic f68lf | ChEMBL registry synonym — accepted as the source's own label CHEMBL3137355 ↗ |
| Known as | Poloxalkol | ChEMBL registry synonym — accepted as the source's own label CHEMBL3137355 ↗ |
| Known as | poloxamer 188 | “MST-188 (Purified Poloxamer 188) Injection in Subjects With Sickle Cell Disease Experiencing Vaso Occlusive Crisis” NCT01737814 ↗2“single treatment of VLTS-934 (84 mL, or a total of 420 mg poloxamer 188) or placebo” NCT00113009 ↗ |
| Known as | Poloxamer 188lf | ChEMBL registry synonym — accepted as the source's own label CHEMBL3137355 ↗ |
| Known as | Polykol | ChEMBL registry synonym — accepted as the source's own label CHEMBL3137355 ↗ |
| Known as | Purified Poloxamer 188 | “MST-188 (Purified Poloxamer 188) Injection” NCT02449616 ↗ |
| Known as | VLTS-934 | “single treatment of VLTS-934 (84 mL, or a total of 420 mg poloxamer 188) or placebo” NCT00113009 ↗ |
| Modality | Small molecule | — CHEMBL3137355 ↗ |
| Route | Intramuscular | “administered as 21 intramuscular (IM) injections of 2 mL each” NCT00113009 ↗ |