drugset / Trial / NCT02596477

Evaluation of Vepoloxamer in Chronic Heart Failure

NCT02596477 ↗

Phase 2 Terminated 10 enrolled Mast Therapeutics, Inc.
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to evaluate whether vepoloxamer can provide a blood chemical marker and functional benefit to damaged heart muscle cells. This will be evaluated by measurement of blood-based laboratory markers, exercise tolerance, and echocardiograms. In addition, the safety and blood levels of vepoloxamer in subjects with chronic heart failure will be evaluated.

Timeline

Start
2015-10
Primary completion
2016-10
Completion
—

Outcome

Outcome not reported

Stopped: “Terminated for administrative reasons not related to safety or efficacy”

Drugs

EvaluationDrugModalityDoseRoute
Subject Vepoloxamer Small molecule 225 mg/kg Intravenous
Subject Vepoloxamer Small molecule 450 mg/kg Intravenous

Indications