Drugs / OXYCODEGOL
OXYCODEGOL
also known as
NKTR-181 · Loxicodegol · NKTR-181 phosphate · Oxicodegol · Oxicodegol phosphate · OXYCODEGOL PHOSPHATE
Small molecule targets OPRM1 via activation
Trials 4 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT03802227 | Oct 2018 → Dec 2019 | — | Nektar Therapeutics | Terminated | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT01619839 | Jun 2012 → Aug 2013 | osteoarthritis, knee | Nektar Therapeutics | Completed | No outcome recorded |
| Phase 32 trials | ||||||
| Phase 3 | NCT02367820 | Apr 2015 → Dec 2017 | chronic pain syndrome | Nektar Therapeutics | Completed | No outcome recorded |
| Phase 3 | NCT02362672 | Mar 2015 → Dec 2016 | chronic pain syndrome | Nektar Therapeutics | Completed | No outcome recorded |
Evidence & citations 10 cited values
Every value below carries the sentence it was read from. 6 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | OXYCODEGOL | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297632 ↗ |
| Known as | Loxicodegol | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297632 ↗ |
| Known as | NKTR-181 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT03802227 ↗ |
| Known as | NKTR-181 phosphate | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297632 ↗ |
| Known as | Oxicodegol | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297632 ↗ |
| Known as | Oxicodegol phosphate | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297632 ↗ |
| Known as | OXYCODEGOL PHOSPHATE | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297632 ↗ |
| Action | Activate | “Mu opioid receptor agonist” CHEMBL4297632 ↗1“mu-opioid receptor agonist” PMID 30747908 ↗ Jun 2019 |
| Modality | Small molecule | “a new opioid molecule, NKTR-181” NCT02362672 ↗ |
| Target | OPRM1 | “Mu opioid receptor agonist” CHEMBL4297632 ↗ |