drugset / Trial / NCT01619839

A Phase 2 Study To Assess The Efficacy, Tolerability, And Safety OF NKTR-181 In Subjects With Chronic OA Knee Pain

NCT01619839

Phase 2 Completed 296 enrolled Nektar Therapeutics
RandomizedParallel-groupQuadruple-blindTreatment

Summary

NKTR-181 is being developed as an analgesic compound for the treatment of moderate to severe chronic pain - active as a mu agonist, but with inherent molecular properties designed to provide a unique clinical profile, including most notably, reduced CNS side effects and an attenuated attractiveness as a target of abuse.

Timeline

Start
2012-06
Primary completion
2013-08
Completion
2013-09

Drugs

EvaluationDrugModalityDoseRoute
Subject OXYCODEGOL Small molecule 100 mg
Subject OXYCODEGOL Small molecule 200 mg
Subject OXYCODEGOL Small molecule 300 mg
Subject OXYCODEGOL Small molecule 400 mg

Indications