drugset / Trial / NCT01619839
A Phase 2 Study To Assess The Efficacy, Tolerability, And Safety OF NKTR-181 In Subjects With Chronic OA Knee Pain
RandomizedParallel-groupQuadruple-blindTreatment
Summary
NKTR-181 is being developed as an analgesic compound for the treatment of moderate to severe chronic pain - active as a mu agonist, but with inherent molecular properties designed to provide a unique clinical profile, including most notably, reduced CNS side effects and an attenuated attractiveness as a target of abuse.
Timeline
- Start
- 2012-06
- Primary completion
- 2013-08
- Completion
- 2013-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | OXYCODEGOL | Small molecule | 100 mg | — |
| Subject | OXYCODEGOL | Small molecule | 200 mg | — |
| Subject | OXYCODEGOL | Small molecule | 300 mg | — |
| Subject | OXYCODEGOL | Small molecule | 400 mg | — |