Drugs / Tiopronin
Tiopronin
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | THIOLA | — | 1988-08-11 | fda.gov ↗ |
Trials 3
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 22 trials · 1 missed | ||||||
| Phase 2 | NCT03663855 | Nov 2018 → Sep 2019 | cystinuria | NYU Langone Health | Completed | No outcome recorded |
| Phase 2 | NCT01095731 | Apr 2010 → Jul 2012 | acquired aneurysmal subarachnoid hemorrhage | E. Sander Connolly | Completed | Missed primary |
| Phase 41 trial | ||||||
| Phase 4 | NCT02125721 | Jun 2012 → Dec 2017 | cystinuria | NYU Langone Health | Completed | No outcome recorded |
| Comparator or background therapy1 trial | ||||||
| Phase 2 | NCT02734966 Comparator | Dec 2007 → Dec 2008 | drug-induced liver injury | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Completed | No outcome recorded |
Press releases naming this drug 3 releases
| Date | Issuer | Release |
|---|---|---|
| 2021-05-17 | Teva Branded Pharmaceutical Products R&D, Inc. | Teva Announces the U.S. Launch of the First Generic Version of THIOLA® (tiopronin) tablets tevapharm.com ↗ |
| 2016-05-02 | Harrow Inc | Imprimis Pharmaceuticals Begins Dispensing Lower Cost Alternative to Thiola® harrow.com ↗ |
| 2016-02-10 | Harrow Inc | Imprimis Pharmaceuticals to Make a Lower Cost Compounded and Customizable Alternative to Thiola® harrow.com ↗ |
Evidence & citations 10 cited values
Every value below carries the sentence it was read from. 5 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Tiopronin | ClinicalTrials.gov intervention name — accepted as the source's own label NCT03663855 ↗ |
| Known as | Acadione | ChEMBL registry synonym — accepted as the source's own label CHEMBL1314 ↗ |
| Known as | Captimer | ChEMBL registry synonym — accepted as the source's own label CHEMBL1314 ↗ |
| Known as | NSC-760416 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1314 ↗ |
| Known as | Thiola | ChEMBL registry synonym — accepted as the source's own label CHEMBL1314 ↗ |
| Known as | Thiola ec | ChEMBL registry synonym — accepted as the source's own label CHEMBL1314 ↗ |
| Known as | Tiopronina | ChEMBL registry synonym — accepted as the source's own label CHEMBL1314 ↗ |
| Known as | Tiopronine | ChEMBL registry synonym — accepted as the source's own label CHEMBL1314 ↗ |
| Modality | Small molecule | — CHEMBL1314 ↗ |
| Route | Oral | “500mg PO BID x 7 days” NCT02125721 ↗ |