Drugs / LY377604
last change Jun 2010 re-read 2 minutes ago

LY377604

Small molecule targets ADRB1, ADRB2, ADRB3 via inhibition / activation

Developed for
obesity disorder
Investigated by
Eli Lilly and Company

Trials 1 · a red edge is where a trial was stopped

201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT00993421 Oct 2009 → Jun 2010 obesity disorder Eli Lilly and Company Terminated No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as LY377604 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00993421
Action Activate “Beta-3 adrenergic receptor agonist” CHEMBL2012520
Action Inhibit “Beta-2 adrenergic receptor antagonist” CHEMBL2012520
1

“Beta-1 adrenergic receptor antagonist” CHEMBL2012520

Modality Small molecule CHEMBL2012520
Route Oral “Given daily, orally for 24 weeks” NCT00993421
Target ADRB1 “Beta-1 adrenergic receptor antagonist” CHEMBL2012520
Target ADRB2 “Beta-2 adrenergic receptor antagonist” CHEMBL2012520
Target ADRB3 “Beta-3 adrenergic receptor agonist” CHEMBL2012520