Drugs / Patupilone
Patupilone
Trials 28
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 112 trials | ||||||
| Phase 1 | NCT00496600 | Jul 2007 → Feb 2011 | refractory malignant neoplasm | University of Medicine and Dentistry of New Jersey | Completed | No outcome recorded |
| Phase 1 | NCT00442741 | Jul 2007 | cancer | Novartis Pharmaceuticals | Withdrawn | No outcome recorded |
| Phase 1 | NCT00468260 | May 2007 → ? | cancer | Novartis Pharmaceuticals | Terminated | No outcome recorded |
| Phase 1 | NCT00448396 | Mar 2007 → Feb 2008 | cancer | Novartis Pharmaceuticals | Completed | No outcome recorded |
| Phase 1 | NCT00420615 | Dec 2006 → Aug 2008 | cancer | Novartis Pharmaceuticals | Completed | No outcome recorded |
| Phase 1 | NCT00412789 | Aug 2006 → Jan 2008 | neoplasm | Novartis Pharmaceuticals | Completed | No outcome recorded |
| Phase 1 | NCT00426582 | Aug 2006 → Aug 2010 | cancer | Novartis Pharmaceuticals | Completed | No outcome recorded |
| Phase 1 | NCT00426140 | Aug → Nov 2006 | cancer | Novartis Pharmaceuticals | Completed | No outcome recorded |
| Phase 1 | NCT00421044 | May 2006 → Feb 2008 | cancer | Novartis Pharmaceuticals | Completed | No outcome recorded |
| Phase 1 | NCT00420524 | Jan 2006 → Jul 2010 | cancer | Novartis Pharmaceuticals | Completed | No outcome recorded |
| Phase 1 | NCT00328458 | Feb 2004 → May 2008 | central nervous system neoplasm, head and neck neoplasm | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | Completed | No outcome recorded |
| Phase 1 | NCT00969046 | Nov 2003 → Nov 2006 | colorectal cancer | Novartis Pharmaceuticals | Completed | No outcome recorded |
| Phase 1/23 trials | ||||||
| Phase 1/2 | NCT00715013 | Jul 2008 → Dec 2010 | brain glioblastoma | University of Zurich | Completed | No outcome recorded |
| Phase 1/2 | NCT00159484 | Oct 2004 → Jan 2015 | colon carcinoma | University of Southern California | Completed | No outcome recorded |
| Phase 1/2 | NCT00171834 | Aug 2003 → Sep 2008 | non-small cell lung carcinoma | Novartis Pharmaceuticals | Completed | No outcome recorded |
| Phase 212 trials | ||||||
| Phase 2 | NCT00407251 | Feb 2007 → Jun 2010 | hormone-resistant prostate carcinoma | British Columbia Cancer Agency | Completed | No outcome recorded |
| Phase 2 | NCT00450866 | Jan 2007 → Jun 2011 | breast cancer, metastatic malignant neoplasm | David Peereboom, MD | Completed | No outcome recorded |
| Phase 2 | NCT00411528 | Sep 2006 → Sep 2012 | metastatic prostate carcinoma | Novartis Pharmaceuticals | Completed | No outcome recorded |
| Phase 2 | NCT00273312 | Jan → Oct 2006 | hepatocellular carcinoma | Novartis Pharmaceuticals | Completed | No outcome recorded |
| Phase 2 | NCT00219297 | Nov 2005 → Jun 2010 | metastatic malignant neoplasm in the brain, non-small cell lung carcinoma | Novartis Pharmaceuticals | Completed | No outcome recorded |
| Phase 2 | NCT00050349 | Jul 2002 → Apr 2007 | carcinoid tumor | Novartis Pharmaceuticals | Completed | No outcome recorded |
| Phase 2 | NCT00035087 | May 2002 → Mar 2003 | colonic neoplasm | Novartis Pharmaceuticals | Completed | No outcome recorded |
| Phase 2 | NCT00035243 | Apr 2002 → Aug 2003 | kidney neoplasm | Novartis Pharmaceuticals | Completed | No outcome recorded |
| Phase 2 | NCT00035165 | Mar 2002 → May 2003 | melanoma | Novartis Pharmaceuticals | Completed | No outcome recorded |
| Phase 2 | NCT00035126 | Jan 2002 → Nov 2003 | breast neoplasm | Novartis Pharmaceuticals | Completed | No outcome recorded |
| Phase 2 | NCT00035113 | Jan 2002 → Jan 2004 | prostate cancer | Novartis Pharmaceuticals | Completed | No outcome recorded |
| Phase 2 | NCT00035100 | Sep 2001 → Jun 2003 | fallopian tube neoplasm, ovarian neoplasm, peritoneal neoplasm | Novartis Pharmaceuticals | Completed | No outcome recorded |
| Phase 31 trial · 1 missed | ||||||
| Phase 3 | NCT00262990 | Nov 2005 → Feb 2010 | fallopian tube cancer, ovarian carcinoma, peritoneum cancer | Novartis Pharmaceuticals | Completed | Missed primary |
Evidence & citations 10 cited values
Every value below carries the sentence it was read from. 29 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | patupilone | “EPO906 (patupilone)” NCT00969046 ↗ |
| Known as | Epithilone b | ChEMBL registry synonym — accepted as the source's own label CHEMBL94657 ↗ |
| Known as | Epo b | ChEMBL registry synonym — accepted as the source's own label CHEMBL94657 ↗ |
| Known as | EPO906 | “An Open-label Single Center Study to Characterize the Absorption, Distribution, Metabolism, and Elimination (ADME) of Patupilone (EPO906) After a Single Intravenous...” NCT00426140 ↗9“This study will examine whether the investigational drug EPO906, given by intravenous infusion (IV directly into the vein), is effective in shrinking tumors and preventing the...” NCT00035126 ↗ “An Open-label, Multi-center, Phase II Study to Evaluate the Activity of Patupilone (EPO906), in the Treatment of Recurrent or Progressive Brain Metastases in Patients With...” NCT00219297 ↗ “patupilone (EPO906)” NCT00262990 ↗ “Patupilone/EPO906” NCT00420524 ↗ “Patupilone/EPO906” NCT00421044 ↗ |
| Known as | EPO906A | “A Phase II Study of Patupilone (EPO906A) as a Second Line Chemotherapy in Patients With Hormone Refractory Prostate Cancer” NCT00407251 ↗ |
| Known as | epothilone B | “EPO906 (epothilone B)” NCT00328458 ↗7“EPO906 epothilone B” NCT00050349 ↗ |
| Known as | GNF-PF-193 | ChEMBL registry synonym — accepted as the source's own label CHEMBL94657 ↗ |
| Known as | Patupilona | ChEMBL registry synonym — accepted as the source's own label CHEMBL94657 ↗ |
| Modality | Small molecule | — CHEMBL94657 ↗ |
| Route | Intravenous | “given by intravenous infusion” NCT00035100 ↗ |