drugset / Trial / NCT00420615

Evaluate the Effects of Patupilone on the Pharmacokinetics of Midazolam and Omeprazole in Patients With Advanced Malignancies

NCT00420615

Phase 1 Completed 34 enrolled Novartis Pharmaceuticals
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the potential inhibitory effects of patupilone on metabolism using midazolam and omeprazole as the respective probe drugs.

Timeline

Start
2006-12
Primary completion
2008-08
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Midazolam Small molecule
Subject Omeprazole Other / unclassified
Subject Patupilone Small molecule

Indications