Drugs / Camonsertib

Trials 9 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT07156227 Feb 2027 → May 2029 expected hypopharynx squamous cell carcinoma, laryngeal squamous cell carcinoma, oral cavity squamous cell carcinoma, oropharynx squamous cell carcinoma +1 National Cancer Institute (NCI) Recruiting No outcome recorded
Phase 1 NCT04855656 Apr 2021 → Dec 2027 expected neoplasm Debiopharm International SA Recruiting No outcome recorded
Phase 1/25 trials
Phase 1/2 NCT05566574 Sep 2022 → Sep 2026 expected metastatic malignant neoplasm Memorial Sloan Kettering Cancer Center Active not recruiting No outcome recorded
Phase 1/2 NCT05405309 Sep 2022 → Oct 2023 chronic lymphocytic leukemia/small lymphocytic lymphoma University of Utah Terminated No outcome recorded
Phase 1/2 NCT04972110 Jul 2021 → Nov 2024 Repare Therapeutics Terminated No outcome recorded
Phase 1/2 NCT04497116 Jul 2020 → Jun 2025 neoplasm Repare Therapeutics Completed No outcome recorded
Phase 1/2 NCT03337698 Dec 2017 → Oct 2025 non-small cell lung carcinoma Hoffmann-La Roche Terminated No outcome recorded
Phase 22 trials
Phase 2 NCT05601440 Jun 2023 → Dec 2027 expected female breast carcinoma Canadian Cancer Trials Group Recruiting No outcome recorded
Phase 2 NCT04589845 Jan 2021 → Sep 2032 expected cancer Hoffmann-La Roche Active not recruiting No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT05605509 Comparator May 2023 → Nov 2025 cancer of unknown primary site Canadian Cancer Trials Group Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 13 sources stand behind the page.

FieldValueCited text
Known as camonsertib “RP-3500 (camonsertib, ATR inhibitor) in combination with niraparib or olaparib (PARP inhibitors)” NCT04972110
4

“the ATRi camonsertib (RP-3500)” PMID 37277454 Jun 2023

NCT04589845

NCT03337698

NCT07156227

Known as ATR INHIBITOR 4 ChEMBL registry synonym — accepted as the source's own label CHEMBL5095260
Known as RP-3500 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04972110
6

NCT05405309

NCT05601440

NCT05566574

NCT04497116

NCT04855656

NCT05605509

Action Inhibit “selective oral inhibitor of ataxia telangiectasia and Rad3-related (ATR) kinase” PMID 38710487 Sep 2024
Modality Small molecule CHEMBL5095260
Route Oral “Camonsertib is administered orally on Days 1-3, Days 8-10 of a 21 day cycle.” NCT03337698
Target ATR “selective oral inhibitor of ataxia telangiectasia and Rad3-related (ATR) kinase” PMID 38710487 Sep 2024