drugset / Trial / NCT04855656

Study of Lunresertib Alone or in Combination With RP-3500 or Debio 0123 in Patients With Advanced Solid Tumors

NCT04855656

Phase 1 Recruiting 464 enrolled Debiopharm International SA
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The primary purpose of this study is to assess the safety and tolerability of lunresertib alone and in combination with RP-3500 or in combination with Debio 0123 in patients with eligible advanced solid tumors, determine the maximum tolerated dose (MTD) and assess preliminary anti-tumor activity.

Timeline

Start
2021-04-30
Primary completion
2027-12
Completion
2028-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Camonsertib Small molecule Oral
Subject Debio 0123 Unknown Oral
Subject Lunresertib Small molecule Oral

Indications