Drugs / Navlimetostat
last change Aug 2026 re-read 9 days ago

Navlimetostat

also known as BMS-986504

targets PRMT5 via inhibition

Developed for
non-small cell lung carcinoma · pancreatic ductal adenocarcinoma
Investigated by
Bristol-Myers Squibb · M.D. Anderson Cancer Center

Trials 5

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT07800897 Aug 2026 → Mar 2027 expected — Bristol-Myers Squibb Recruiting No outcome recorded
Phase 1 NCT07544628 Apr → Nov 2026 expected — Bristol-Myers Squibb Recruiting No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT07579221 Jul 2026 → Aug 2029 expected non-small cell lung carcinoma M.D. Anderson Cancer Center Recruiting No outcome recorded
Phase 21 trial
Phase 2 NCT06855771 Sep 2025 → Dec 2028 expected non-small cell lung carcinoma Bristol-Myers Squibb Recruiting No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT07076121 Oct 2025 → May 2029 expected pancreatic ductal adenocarcinoma Bristol-Myers Squibb Active not recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Navlimetostat “Navlimetostat (BMS-986504)” NCT06855771 ↗
4

NCT07579221 ↗

NCT07544628 ↗

NCT07800897 ↗

NCT07076121 ↗

Known as BMS-986504 “Navlimetostat (BMS-986504)” NCT06855771 ↗
Action Inhibit “PRMT5 inhibitor” NCT07076121 ↗
Route Oral “administered orally once daily (QD)” NCT07579221 ↗
Target PRMT5 “PRMT5 inhibitor” NCT07076121 ↗