drugset / Trial / NCT06855771

A Study of Navlimetostat (BMS-986504) Alone or in Combination With Izalontamab Brengitecan in Participants With Pre-treated Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) With Homozygous MTAP Deletion or MTAP Loss (MountainTAP-9)

NCT06855771 ↗

Phase 2 Recruiting 182 enrolled Bristol-Myers Squibb
RandomizedSequentialOpen-labelTreatment

Summary

The purpose of this study is to evaluate the safety and efficacy of Navlimetostat (BMS-986504) monotherapy or in combination with Izalontamab Brengitecan in participants with advanced or metastatic Non-small Cell Lung Cancer (NSCLC) with homozygous MTAP deletion or MTAP loss after progression on prior therapies.

Timeline

Start
2025-09-09
Primary completion
2028-12-29
Completion
2031-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject BL-B01D1 Unknown — —
Subject Navlimetostat Unknown — —