Drugs / Benoxinate
Benoxinate
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | BENOXINATE HYDROCHLORIDE | — | 1975-01-14 | fda.gov ↗ |
Trials 4 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT06857890 | Dec 2024 → Dec 2026 expected | pharyngitis | Valenta Pharm JSC | Recruiting | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT06843018 | Nov 2024 → Dec 2026 expected | acute pharyngitis, nasopharyngitis | Valenta Pharm JSC | Recruiting | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT06461975 | Jan → Apr 2023 | retinopathy of prematurity | Alexandria University | Completed | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT05733741 | Jan → Apr 2023 | myopia | Assiut University | Completed | No outcome recorded |
Also used as a comparator or background therapy in 7 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 22 trials | ||||||
| Phase 2 | NCT03933280 Comparator | Jul 2019 → Dec 2020 | — | Menoufia University | Completed | No outcome recorded |
| Phase 2 | NCT03735368 Comparator | Dec 2018 → Oct 2019 | — | Abd-Elazeem Abd-Elhameed Elbakry | Completed | No outcome recorded |
| Phase 32 trials | ||||||
| Phase 3 | NCT05926258 Comparator | May 2024 → Mar 2025 | — | Sintetica SA | Completed | No outcome recorded |
| Phase 3 | NCT07230548 Comparator | Jun → Oct 2020 | eye adnexa disorder | Medical University of Vienna | Completed | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT05666362 Comparator | Jan 2023 → Dec 2024 | — | Alexandria University | Completed | No outcome recorded |
| Phase not applicable2 trials | ||||||
| — | NCT04193774 Comparator | Aug 2019 → Dec 2021 | — | Universitaire Ziekenhuizen KU Leuven | Completed | No outcome recorded |
| — | NCT02528123 Background | Apr 2016 → Dec 2020 | myopia | London Vision Clinic | Completed | No outcome recorded |
Evidence & citations 16 cited values
Every value below carries the sentence it was read from. 12 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Benoxinate | ClinicalTrials.gov intervention name — accepted as the source's own label NCT05733741 ↗ |
| Known as | Benoxidia | “Preservative-free Benoxinate hydrochloride 0.4% (Benoxidia unit-dose vials [UD], Orchidia pharmaceutical Ind., Egypt)” NCT05733741 ↗ |
| Known as | Benoxinate hcl | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200 ↗ |
| Known as | Benoxinate hydrochloride | “Preservative-free Benoxinate hydrochloride 0.4% (Benoxidia unit-dose vials [UD], Orchidia pharmaceutical Ind., Egypt)” NCT05733741 ↗4“topical anesthesia of the eye by Benoxinate Hydrochloride 0.4% Eye Drops” NCT03735368 ↗ |
| Known as | Benoxinate hydrochloride component of altafluor benox | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200 ↗ |
| Known as | Conjucain | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200 ↗ |
| Known as | Dorsacain | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200 ↗ |
| Known as | Monofree oxybuprocaine | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200 ↗ |
| Known as | NSC-759847 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200 ↗ |
| Known as | Oxibuprocaina | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200 ↗ |
| Known as | Oxybucaine | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200 ↗ |
| Known as | Oxybuprocaine | “gramicidine C + oxybuprocaine + cetylpyridine chloride” NCT06843018 ↗ |
| Known as | Oxybuprocaine hcl | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200 ↗ |
| Known as | Oxybuprocaine Hydrochloride | “Oxybuprocaine Hydrochloride 4 Mg/mL Eye Drops” NCT05926258 ↗1“Oxybuprocaine Hydrochloride 0.4% Eye Drops” NCT04193774 ↗ |
| Modality | Small molecule | — CHEMBL1200 ↗ |
| Route | Topical | “Oxybuprocaine 0.4% eye drops will be used as an anaesthetic during the procedure” NCT02528123 ↗ |