drugset / Trial / NCT03735368

Dexmedetomidine and Pregabalin for Conscious Sedation During Cataract Surgery

NCT03735368

Phase 2 Completed 60 enrolled Abd-Elazeem Abd-Elhameed Elbakry
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Although topical anesthesia by eye drops for cataract surgery is a non-invasive technique but it may provide insufficient anesthesia which requires the intraoperative use of additional topical local anesthetics and raises the need for sedation.

Timeline

Start
2018-12-10
Primary completion
2019-10-30
Completion
2019-11-29

Drugs

EvaluationDrugModalityDoseRoute
Comparator Pregabalin Small molecule 150 mg
Comparator Benoxinate Small molecule 0.4 % Topical
Comparator Dexmedetomidine Other / unclassified 0.5 ug/kg
Comparator Dexmedetomidine Other / unclassified 1 ug/kg

Indications

No indication recorded.