Dexmedetomidine
Other / unclassified targets ADRA2A via activation
Regulatory milestones approvals, filings & regulatory actions · 7 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Label expansion | US (FDA) | IGALMI | — | 2025-11-19 | fda.gov ↗ |
| Label expansions (3) | US (FDA) | PRECEDEX | — | 2008-10-17 – 2022-12-16 | fda.gov ↗ |
| Label expansion | US (FDA) | DEXMEDETOMIDINE HYDROCHLORIDE | — | 2016-09-19 | fda.gov ↗ |
| Approved | EU (EMA) | Dexdor | — | 2011-09-15 | europa.eu ↗ |
| Approved | US (FDA) | PRECEDEX | — | 1999-12-17 | fda.gov ↗ |
Trials 1,064 · started per year
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 031 trials | ||||||
| Phase 0 | NCT06824077 | Aug 2026 → Mar 2027 expected | delirium | University of Alberta | Not yet recruiting | No outcome recorded |
| Phase 0 | NCT07211399 | Jul 2026 → Dec 2030 | substance-related disorder | Jacques E. Chelly | Withdrawn | No outcome recorded |
| Phase 0 | NCT07502651 | May 2025 → Mar 2027 expected | — | Postgraduate Institute of Dental Sciences Rohtak | Enrolling by invitation | No outcome recorded |
| Phase 0 | NCT06756178 | Jan 2025 → Nov 2026 expected | delirium | Assiut University | Not yet recruiting | No outcome recorded |
| Phase 0 | NCT05264077 | Nov 2024 → Jun 2025 overdue | — | Sheikh Zayed Medical College | Not yet recruiting | No outcome recorded |
| Phase 0 | NCT06229054 | Feb → Jul 2024 | — | Cairo University | Completed | No outcome recorded |
| Phase 0 | NCT06215768 | Jan → Sep 2024 | delirium | Esraa Abdel Azez Soltan Mohamed Zayed | Unknown | No outcome recorded |
| Phase 0 | NCT07651488 | Mar → Sep 2023 | — | Liaquat National Hospital & Medical College | Completed | No outcome recorded |
| Phase 0 | NCT05505630 | Jan 2023 → Dec 2025 | nicotine dependence | Wake Forest University Health Sciences | Completed | No outcome recorded |
| Phase 0 | NCT05574179 | Jan → Jul 2023 | — | Sheikh Zayed Medical College | Unknown | No outcome recorded |
| Phase 0 | NCT05351489 | May 2022 → Oct 2023 | — | Mansoura University | Completed | No outcome recorded |
| Phase 0 | NCT05435560 | Apr 2022 → Apr 2023 | — | Massachusetts General Hospital | Unknown | No outcome recorded |
| Phase 0 | NCT03757897 | Dec 2021 → Dec 2022 | intracranial hypertension | Yale University | Withdrawn | No outcome recorded |
| Phase 0 | NCT05244252 | Oct 2021 → Mar 2022 | — | Sheikh Zayed Medical College | Unknown | No outcome recorded |
| Phase 0 | NCT05246371 | Jun → Nov 2021 | — | Ain Shams University | Unknown | No outcome recorded |
| Phase 0 | NCT03817034 | Mar 2021 | — | Massachusetts General Hospital | Withdrawn | No outcome recorded |
| Phase 0 | NCT04757675 | Mar → Sep 2021 | separation anxiety disorder | Eye & ENT Hospital of Fudan University | Completed | No outcome recorded |
| Phase 0 | NCT04646317 | Dec 2020 → Mar 2021 | gallbladder disorder, hypertensive disorder | Dr. Ruth K.M. Pfau Civil Hospital, Karachi | Unknown | No outcome recorded |
| Phase 0 | NCT04436731 | Dec 2020 → Jun 2026 overdue | obesity disorder | University of Missouri-Columbia | Active not recruiting | No outcome recorded |
| Phase 0 | NCT04648540 | Dec 2020 → Aug 2022 | — | Cairo University | Completed | No outcome recorded |
| Phase 0 | NCT04142840 | Nov 2019 → Aug 2021 | — | RenJi Hospital | Unknown | No outcome recorded |
| Phase 0 | NCT04171349 | Jun → Oct 2019 | kidney failure | Ain Shams University | Completed | No outcome recorded |
| Phase 0 | NCT03770130 | Jan 2019 → Oct 2022 | — | RenJi Hospital | Completed | No outcome recorded |
| Phase 0 | NCT03738059 | Nov 2018 → Mar 2019 | — | Assiut University | Unknown | No outcome recorded |
| Phase 0 | NCT03719001 | Oct 2018 → Jun 2022 | vascular disorder | University of California, San Francisco | Completed | No outcome recorded |
| Phase 0 | NCT03596775 | Sep 2018 → Jun 2019 | — | Xuzhou Medical University | Unknown | No outcome recorded |
| Phase 0 | NCT03095469 | Aug → Nov 2017 | — | First Affiliated Hospital Xi'an Jiaotong University | Unknown | No outcome recorded |
| Phase 0 | NCT03466242 | Jan 2017 → Jan 2020 | — | Phoenix Children's Hospital | Withdrawn | No outcome recorded |
| Phase 0 | NCT02529202 | Mar → Nov 2016 | brain hypoxia - ischemia | Seattle Children's Hospital | Completed | No outcome recorded |
| Phase 0 | NCT02768688 | Jul 2014 → Feb 2017 | — | University of Pennsylvania | Completed | No outcome recorded |
| Phase 0 | NCT01927640 | Feb 2013 → Jan 2014 | acute coronary syndrome, intermediate coronary syndrome | Cedars-Sinai Medical Center | Completed | No outcome recorded |
| Phase 143 trials | ||||||
| Phase 1 | NCT05619627 | Aug 2026 → Aug 2027 expected | — | Children's Mercy Hospital Kansas City | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT07167316 | May → Dec 2026 expected | — | Hans-Peter Landolt | Recruiting | No outcome recorded |
| Phase 1 | NCT07603596 | May 2026 → Apr 2028 expected | delirium, digestive system neoplasm | Qianfoshan Hospital | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT07677917 | Jan → Jul 2026 overdue | — | Ain Shams University | Enrolling by invitation | No outcome recorded |
| Phase 1 | NCT06335407 | Jul 2025 → Mar 2026 overdue | alcohol-related disorders, post-traumatic stress disorder | Pharmacotherapies for Alcohol and Substance Use Disorders Alliance | Recruiting | No outcome recorded |
| Phase 1 | NCT07023991 | May → Aug 2025 overdue | — | Ain Shams University | Enrolling by invitation | No outcome recorded |
| Phase 1 | NCT07140627 | Aug 2024 → Jan 2025 | — | Allama Iqbal Medical College | Completed | No outcome recorded |
| Phase 1 | NCT06304909 | May 2024 → Mar 2025 | — | Assiut University | Completed | No outcome recorded |
| Phase 1 | NCT06631625 | Sep 2023 → Sep 2024 | — | Alexandria University | Completed | No outcome recorded |
| Phase 1 | NCT07051512 | Jul 2023 → Jun 2024 | — | Tanta University | Completed | No outcome recorded |
| Phase 1 | NCT06614010 | Feb 2023 → Sep 2025 overdue | — | Qianfoshan Hospital | Recruiting | No outcome recorded |
| Phase 1 | NCT05880693 | Jan 2022 → Apr 2023 | hypotensive disorder | mohamed | Completed | No outcome recorded |
| Phase 1 | NCT04205539 | Dec 2021 → Dec 2022 | Alzheimer disease | Neurological Associates of West Los Angeles | Withdrawn | No outcome recorded |
| Phase 1 | NCT04827056 | Nov 2021 → May 2023 | alcohol-related disorders, post-traumatic stress disorder | Pharmacotherapies for Alcohol and Substance Use Disorders Alliance | Completed | No outcome recorded |
| Phase 1 | NCT05124067 | Oct 2021 → Jan 2022 | delirium | Tanta University | Completed | No outcome recorded |
| Phase 1 | NCT05025605 | Aug 2021 → Jul 2027 expected | bipolar I disorder, bipolar II disorder, schizoaffective disorder, schizophrenia +1 | BioXcel Therapeutics Inc | Recruiting | No outcome recorded |
| Phase 1 | NCT04941040 | Jul → Oct 2021 | supratentorial cancer | Kasr El Aini Hospital | Completed | No outcome recorded |
| Phase 1 | NCT04658732 | Dec 2020 → Jun 2021 | — | Ehab Tarek Fahmy | Unknown | No outcome recorded |
| Phase 1 | NCT04062123 | Jul 2020 → Apr 2024 | — | Keith M Vogt | Completed | No outcome recorded |
| Phase 1 | NCT04531371 | Jun → Sep 2020 | — | South Valley University | Unknown | No outcome recorded |
| Phase 1 | NCT04200235 | Jan → Aug 2020 | — | Jiangsu HengRui Medicine Co., Ltd. | Completed | No outcome recorded |
| Phase 1 | NCT04010305 | May → Jul 2019 | schizophrenia | BioXcel Therapeutics Inc | Completed | No outcome recorded |
| Phase 1 | NCT03668951 | Aug 2018 → May 2022 | heart disorder | Children's Hospital Medical Center, Cincinnati | Completed | No outcome recorded |
| Phase 1 | NCT03417999 | Jun 2018 → Oct 2021 | congenital heart disease | Children's Hospital of Philadelphia | Terminated | No outcome recorded |
| Phase 1 | NCT03293277 | Jul 2017 → Jul 2018 | — | Jiangsu HengRui Medicine Co., Ltd. | Unknown | No outcome recorded |
| Phase 1 | NCT03126422 | May → Sep 2017 | — | Yangzhou University | Unknown | No outcome recorded |
| Phase 1 | NCT02652507 | Jun 2016 → May 2018 | — | Children's Hospital Medical Center, Cincinnati | Completed | No outcome recorded |
| Phase 1 | NCT02836431 | Jan 2016 → Dec 2017 | heart disorder | Children's Hospital Medical Center, Cincinnati | Completed | No outcome recorded |
| Phase 1 | NCT02515890 | Nov 2015 → Dec 2018 | amnestic disorder | University of Pittsburgh | Completed | No outcome recorded |
| Phase 1 | NCT02250820 | Nov 2014 → Dec 2017 | heart disorder | Children's Hospital Medical Center, Cincinnati | Completed | No outcome recorded |
| Phase 1 | NCT01915277 | Apr 2014 → Oct 2017 | tetralogy of fallot, transposition of the great arteries, ventricular septal defect | Carelon Research | Completed | No outcome recorded |
| Phase 1 | NCT01342328 | May → Nov 2012 | sleep disorder | University of California, San Francisco | Terminated | No outcome recorded |
| Phase 1 | NCT01447875 | May 2011 → Dec 2013 | infectious disease with sepsis | Southeast University, China | Completed | No outcome recorded |
| Phase 1 | NCT01116700 | Dec 2010 → Feb 2012 | epilepsy | University of California, San Francisco | Completed | No outcome recorded |
| Phase 1 | NCT01084473 | Mar → Jun 2010 | — | University of Turku | Completed | No outcome recorded |
| Phase 1 | NCT01736020 | Sep 2009 → Apr 2017 | — | Southern California Institute for Research and Education | Unknown | No outcome recorded |
| Phase 1 | NCT00837187 | Mar → May 2009 | — | University of Turku | Completed | No outcome recorded |
| Phase 1 | NCT00826553 | Jan 2009 → Dec 2013 | delirium, respiratory failure | Vanderbilt University Medical Center | Terminated | No outcome recorded |
| Phase 1 | NCT00747721 | Sep 2008 → Jan 2009 | — | Orion Corporation, Orion Pharma | Completed | No outcome recorded |
| Phase 1 | NCT00576381 | Apr 2006 → Dec 2010 | cardiac ventricle disorder, hypoplastic left heart syndrome, tetralogy of fallot | Athena Zuppa | Completed | No outcome recorded |
| Phase 1 | NCT00142493 | Sep 2004 → Aug 2008 | amnestic disorder | Memorial Sloan Kettering Cancer Center | Completed | No outcome recorded |
| Phase 1 | NCT00573066 | May 2004 → Oct 2006 | hypoplastic left heart syndrome, tetralogy of fallot, tricuspid atresia | Athena Zuppa | Completed | No outcome recorded |
| Phase 1 | NCT00338546 | — | cocaine intoxication | University of Texas Southwestern Medical Center | Withdrawn | No outcome recorded |
| Phase 1/217 trials | ||||||
| Phase 1/2 | NCT07672301 | Mar 2026 → Jun 2027 expected | — | University of Chicago | Recruiting | No outcome recorded |
| Phase 1/2 | NCT07622355 | Sep 2025 → Jun 2026 overdue | thyroid gland disorder | The Second People's Hospital of Huai'an | Active not recruiting | No outcome recorded |
| Phase 1/2 | NCT06970678 | Apr → Jun 2025 overdue | — | Alexandria University | Recruiting | No outcome recorded |
| Phase 1/2 | NCT07024043 | Mar → Sep 2025 overdue | — | Ain Shams University | Active not recruiting | No outcome recorded |
| Phase 1/2 | NCT07099222 | Oct 2024 → Dec 2026 expected | constipation disorder | University of Arizona | Active not recruiting | No outcome recorded |
| Phase 1/2 | NCT06545890 | Aug → Nov 2024 overdue | delirium | Cairo University | Recruiting | No outcome recorded |
| Phase 1/2 | NCT06712186 | Jun → Nov 2024 overdue | anxiety disorder, hypertensive disorder | Liaquat National Hospital & Medical College | Recruiting | No outcome recorded |
| Phase 1/2 | NCT04824144 | Jan 2024 → Jan 2026 overdue | delirium | Bruyère Health Research Institute. | Recruiting | No outcome recorded |
| Phase 1/2 | NCT05712707 | Feb 2023 → Jun 2025 overdue | substance withdrawal syndrome | New York State Psychiatric Institute | Active not recruiting | No outcome recorded |
| Phase 1/2 | NCT04926454 | Sep 2020 → Oct 2021 | neuropathy, painful | Ain Shams University | Unknown | No outcome recorded |
| Phase 1/2 | NCT04470050 | Jun 2020 → Feb 2021 | substance withdrawal syndrome | BioXcel Therapeutics Inc | Completed | No outcome recorded |
| Phase 1/2 | NCT05369468 | Jan 2020 → Nov 2022 | — | Tanta University | Completed | No outcome recorded |
| Phase 1/2 | NCT02818569 | Oct 2016 → Jun 2018 | insomnia | Massachusetts General Hospital | Completed | No outcome recorded |
| Phase 1/2 | NCT02409810 | Apr 2015 → Mar 2020 | anxiety | Ohio State University | Completed | No outcome recorded |
| Phase 1/2 | NCT03613558 | Jul 2014 → Jun 2015 | obstructive sleep apnea syndrome | Montefiore Medical Center | Withdrawn | No outcome recorded |
| Phase 1/2 | NCT01664520 | Jun 2013 → Nov 2016 | brain aneurysm, subarachnoid hemorrhage | Turku University Hospital | Completed | No outcome recorded |
| Phase 1/2 | NCT01606852 | Mar 2013 → Jul 2014 | acute respiratory failure, anxiety | University of Minnesota | Completed | No outcome recorded |
| Phase 265 trials | ||||||
| Phase 2 | NCT07705022 | Jul 2026 → Jan 2028 expected | — | University of Michigan | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT07588802 | Jul 2026 → Apr 2027 expected | — | Massachusetts General Hospital | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT06943404 | Feb → Sep 2026 expected | acute stress disorder, post-traumatic stress disorder | University of North Carolina, Chapel Hill | Recruiting | No outcome recorded |
| Phase 2 | NCT07392177 | Feb 2026 → Mar 2027 expected | insomnia | Woolcock Institute of Medical Research | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT07249827 | Dec 2025 → Jun 2026 | — | McGill University Health Centre/Research Institute of the McGill University Health Centre | Completed | No outcome recorded |
| Phase 2 | NCT07519863 | Nov 2025 → Nov 2026 expected | — | Ain Shams University | Recruiting | No outcome recorded |
| Phase 2 | NCT05057689 | Sep → Oct 2025 | acute stress disorder, anxiety | Nationwide Children's Hospital | Withdrawn | No outcome recorded |
| Phase 2 | NCT07168720 | Aug 2025 → Mar 2026 overdue | — | Guangzhou Novaken Pharm Co., Ltd. | Recruiting | No outcome recorded |
| Phase 2 | NCT06985290 | Jul 2025 → Sep 2027 expected | brain hypoxia - ischemia | Ipsita Goswami | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT07116694 | Jun → Oct 2025 | bipolar I disorder, bipolar II disorder, schizoaffective disorder, schizophrenia +1 | BioXcel Therapeutics Inc | Completed | No outcome recorded |
| Phase 2 | NCT06979791 | Jun → Sep 2025 overdue | — | Cairo University | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT07202624 | Feb → Jun 2025 | pharyngitis | Prince Sultan Military Medical City | Completed | No outcome recorded |
| Phase 2 | NCT06736483 | Feb 2025 → Jul 2027 expected | — | University Hospital, Montpellier | Recruiting | No outcome recorded |
| Phase 2 | NCT06978192 | Dec 2024 → Feb 2026 overdue | herpes zoster | Fenghui Deng | Recruiting | No outcome recorded |
| Phase 2 | NCT06148311 | Jul 2024 → Jan 2027 expected | Riley-Day syndrome | NYU Langone Health | Enrolling by invitation | No outcome recorded |
| Phase 2 | NCT06128356 | Jun 2024 → Sep 2028 expected | Riley-Day syndrome | NYU Langone Health | Active not recruiting | No outcome recorded |
| Phase 2 | NCT06302998 | Jun 2024 → Dec 2025 | infectious disease with sepsis | Mansoura University | Unknown | No outcome recorded |
| Phase 2 | NCT05616364 | Mar 2023 → Mar 2024 | benign shuddering attacks | Sana Bahadur | Unknown | No outcome recorded |
| Phase 2 | NCT05303987 | Oct 2022 → Jan 2027 expected | obstructive sleep apnea syndrome | Erin Kirkham | Recruiting | No outcome recorded |
| Phase 2 | NCT05487196 | Sep 2022 → Jul 2023 | pregnancy disorder | Grace Lim, MD, MS | Completed | No outcome recorded |
| Phase 2 | NCT07081581 | Aug 2022 → Feb 2023 | breast cancer | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey | Completed | No outcome recorded |
| Phase 2 | NCT04772222 | Jun 2022 → Jan 2025 | brain hypoxia - ischemia | University of Utah | Completed | No outcome recorded |
| Phase 2 | NCT05216055 | Apr → Dec 2022 | large intestine disorder | University of Colorado, Denver | Withdrawn | No outcome recorded |
| Phase 2 | NCT05283083 | Mar 2022 → Feb 2023 | infectious disease with sepsis | Mansoura University | Completed | No outcome recorded |
| Phase 2 | NCT05276830 | Feb → Apr 2022 | dementia | BioXcel Therapeutics Inc | Terminated | No outcome recorded |
| Phase 2 | NCT05313386 | Feb 2021 → Feb 2022 | delirium | BioXcel Therapeutics Inc | Withdrawn | No outcome recorded |
| Phase 2 | NCT04391361 | Nov 2020 → Sep 2023 | amyotrophic lateral sclerosis | Ruijin Hospital | Unknown | No outcome recorded |
| Phase 2 | NCT06289335 | Aug 2020 → Sep 2021 | — | Hospital Central "Dr. Ignacio Morones Prieto" | Completed | No outcome recorded |
| Phase 2 | NCT04426552 | Jun → Sep 2020 | craniofacial and skeletal defects | Alexandria University | Unknown | No outcome recorded |
| Phase 2 | NCT04382170 | Jun 2020 → Jun 2021 | delirium | Jeff C. Huffman, MD | Withdrawn | No outcome recorded |
| Phase 2 | NCT03957304 | Feb 2020 → Mar 2022 | — | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | Completed | No outcome recorded |
| Phase 2 | NCT04027829 | Aug → Nov 2019 | — | Seoul National University Hospital | Completed | No outcome recorded |
| Phase 2 | NCT03989609 | Jun 2019 → Feb 2020 | infectious disease with sepsis | Kasr El Aini Hospital | Completed | No outcome recorded |
| Phase 2 | NCT03807297 | Jan → Nov 2019 | — | Rajiv Gandhi Cancer Institute & Research Center, India | Completed | No outcome recorded |
| Phase 2 | NCT03545516 | Sep → Nov 2018 | substance-related disorder | Richmond University Medical Center | Unknown | No outcome recorded |
| Phase 2 | NCT03645603 | Aug 2018 → Jan 2020 | substance withdrawal syndrome | IRCCS Azienda Ospedaliero-Universitaria di Bologna | Terminated | No outcome recorded |
| Phase 2 | NCT03979469 | Aug 2018 → Aug 2019 | — | Athens General Children's Hospital "Pan. & Aglaia Kyriakou" | Completed | No outcome recorded |
| Phase 2 | NCT03293927 | Apr 2018 → Jul 2019 | delirium | Duke University | Withdrawn | No outcome recorded |
| Phase 2 | NCT03799783 | Mar 2018 → Feb 2019 | disruptive behavior disorder | Azienda Ospedaliera di Padova | Completed | No outcome recorded |
| Phase 2 | NCT03434366 | Jan 2018 → Dec 2023 | autism spectrum disorder | Guangzhou Women and Children's Medical Center | Suspended | No outcome recorded |
| Phase 2 | NCT03827408 | Nov 2017 → Aug 2019 | — | Nourhan M.Aly | Completed | No outcome recorded |
| Phase 2 | NCT03348423 | Nov 2017 → Jan 2018 | — | Baudax Bio | Completed | No outcome recorded |
| Phase 2 | NCT03222323 | Jul 2017 → Jan 2018 | — | Zealand University Hospital | Unknown | No outcome recorded |
| Phase 2 | NCT03425734 | May 2017 → May 2018 | congenital heart disease | Mai Madkour | Unknown | No outcome recorded |
| Phase 2 | NCT03102359 | Apr 2017 → Dec 2019 | — | Huazhong University of Science and Technology | Unknown | No outcome recorded |
| Phase 2 | NCT02675049 | Jan → Feb 2016 | — | Tianjin Medical University Cancer Institute and Hospital | Completed | No outcome recorded |
| Phase 2 | NCT02488473 | Aug → Sep 2015 | — | Zealand University Hospital | Completed | No outcome recorded |
| Phase 2 | NCT01969903 | Nov 2014 | — | NYU Langone Health | Withdrawn | No outcome recorded |
| Phase 2 | NCT02284243 | Oct 2014 → Jun 2015 | — | Baudax Bio | Completed | No outcome recorded |
| Phase 2 | NCT02169336 | Jun → Sep 2014 | neuropathy, painful | Baudax Bio | Terminated | No outcome recorded |
| Phase 2 | NCT02492269 | May 2014 → Dec 2024 | congenital heart disease | Aymen N Naguib | Completed | No outcome recorded |
| Phase 2 | NCT02252523 | Apr 2014 → Apr 2015 | brain injury | University Hospital, Clermont-Ferrand | Unknown | No outcome recorded |
| Phase 2 | NCT02375243 | Feb 2014 → Dec 2015 | — | Bambino Gesù Hospital and Research Institute | Completed | No outcome recorded |
| Phase 2 | NCT02866409 | Nov 2013 → Dec 2014 | headache disorder | NAVNEH SAMAGH | Completed | No outcome recorded |
| Phase 2 | NCT02225054 | May 2013 → Mar 2015 | arthropathy, neurological pain disorder | Women's College Hospital | Completed | No outcome recorded |
| Phase 2 | NCT01687751 | Nov 2012 → Nov 2014 | delirium | Fraser Health | Withdrawn | No outcome recorded |
| Phase 2 | NCT01701778 | Oct 2012 → Jan 2014 | cryptorchidism | Yao Yusheng | Completed | No outcome recorded |
| Phase 2 | NCT01845441 | Apr 2012 → Dec 2021 | brain ischemia, intracranial vasospasm, stroke disorder | University Hospitals Cleveland Medical Center | Terminated | No outcome recorded |
| Phase 2 | NCT01378988 | Jun → Aug 2011 | — | Pfizer | Completed | No outcome recorded |
| Phase 2 | NCT01007773 | Jan 2010 → Jan 2011 | traumatic brain injury | University of Maryland, Baltimore | Withdrawn | No outcome recorded |
| Phase 2 | NCT00464451 | Aug 2009 → Dec 2010 | — | Wesley Medical Center | Withdrawn | No outcome recorded |
| Phase 2 | NCT00652028 | Nov 2008 → Apr 2010 | — | Pfizer | Completed | No outcome recorded |
| Phase 2 | NCT00697788 | Jul 2007 → Dec 2008 | — | Massachusetts General Hospital | Completed | No outcome recorded |
| Phase 2 | NCT00351299 | Jan 2006 → Oct 2012 | delirium | Brigham and Women's Hospital | Completed | No outcome recorded |
| Phase 2 | NCT00505804 | Jan 2005 → Nov 2008 | delirium | Austin Health | Completed | No outcome recorded |
| Phase 2/350 trials | ||||||
| Phase 2/3 | NCT07537894 | Jul 2026 → Jul 2027 | post-traumatic stress disorder, pregnancy disorder with abortive outcome | Stanford University | Withdrawn | No outcome recorded |
| Phase 2/3 | NCT07493785 | Jun 2026 → Aug 2032 expected | neonatal respiratory failure, neurodevelopmental disorder | Centre Hospitalier Intercommunal Creteil | Not yet recruiting | No outcome recorded |
| Phase 2/3 | NCT07538284 | May → Dec 2026 expected | delirium, sleep disorder | Sixth Affiliated Hospital, Sun Yat-sen University | Not yet recruiting | No outcome recorded |
| Phase 2/3 | NCT07555821 | Apr → Oct 2026 expected | — | South Egypt Cancer Institute | Not yet recruiting | No outcome recorded |
| Phase 2/3 | NCT06935292 | Apr 2025 → Apr 2026 overdue | — | Tanta University | Not yet recruiting | No outcome recorded |
| Phase 2/3 | NCT06799442 | Mar → Dec 2025 overdue | — | Assiut University | Not yet recruiting | No outcome recorded |
| Phase 2/3 | NCT07290595 | Jan 2025 → Feb 2026 overdue | hypotensive disorder | Sahiwal medical college sahiwal | Recruiting | No outcome recorded |
| Phase 2/3 | NCT06752616 | Dec 2024 → Dec 2027 expected | — | Lone Baandrup | Recruiting | No outcome recorded |
| Phase 2/3 | NCT06662175 | Nov 2024 → Jul 2025 overdue | — | Lady Reading Hospital, Pakistan | Not yet recruiting | No outcome recorded |
| Phase 2/3 | NCT06899841 | Oct 2024 → Oct 2025 overdue | — | Assiut University | Recruiting | No outcome recorded |
| Phase 2/3 | NCT06620393 | Oct 2024 → Jun 2026 overdue | traumatic brain injury | Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal | Not yet recruiting | No outcome recorded |
| Phase 2/3 | NCT06740903 | Aug 2024 → Aug 2025 overdue | cholecystitis | Sahiwal medical college sahiwal | Recruiting | No outcome recorded |
| Phase 2/3 | NCT07368075 | Jul 2024 → Oct 2025 | hypotensive disorder | Sahiwal medical college sahiwal | Completed | No outcome recorded |
| Phase 2/3 | NCT07064720 | Jul 2024 → Dec 2025 | — | Cairo University | Completed | No outcome recorded |
| Phase 2/3 | NCT06382831 | Jun → Aug 2024 | — | Indonesia University | Unknown | No outcome recorded |
| Phase 2/3 | NCT06378827 | Apr → Jul 2024 | acute kidney injury | University of Novi Sad | Unknown | No outcome recorded |
| Phase 2/3 | NCT07590752 | Mar 2024 → Jun 2026 overdue | neuropathy, painful, substance-related disorder | Sahiwal medical college sahiwal | Recruiting | No outcome recorded |
| Phase 2/3 | NCT07241351 | Mar → Nov 2024 | — | Ain Shams University | Completed | No outcome recorded |
| Phase 2/3 | NCT06394375 | Jul → Oct 2023 | — | Indonesia University | Completed | No outcome recorded |
| Phase 2/3 | NCT04106999 | Mar 2023 → Jun 2024 | cancer | University of British Columbia | Unknown | No outcome recorded |
| Phase 2/3 | NCT05579964 | Oct 2022 → Apr 2023 | tetralogy of fallot | National Cardiovascular Center Harapan Kita Hospital Indonesia | Completed | No outcome recorded |
| Phase 2/3 | NCT04656470 | Mar 2022 → May 2025 | — | Massachusetts General Hospital | Completed | No outcome recorded |
| Phase 2/3 | NCT06531603 | Feb 2022 → Jan 2023 | hypotensive disorder | Sahiwal medical college sahiwal | Completed | No outcome recorded |
| Phase 2/3 | NCT05300802 | Dec 2021 → May 2022 | congenital heart disease | National Cardiovascular Center Harapan Kita Hospital Indonesia | Completed | No outcome recorded |
| Phase 2/3 | NCT05375188 | Aug 2021 → Jan 2022 | acute kidney injury | National Institute of Cardiovascular Diseases, Pakistan | Completed | No outcome recorded |
| Phase 2/3 | NCT03285087 | Jun 2021 → Aug 2022 | — | Assiut University | Suspended | No outcome recorded |
| Phase 2/3 | NCT06735443 | Mar 2021 → Apr 2022 | hernia, double inguinal | Sahiwal medical college sahiwal | Completed | No outcome recorded |
| Phase 2/3 | NCT04383418 | May 2020 → Jun 2021 | — | Jiangsu HengRui Medicine Co., Ltd. | Unknown | No outcome recorded |
| Phase 2/3 | NCT04195256 | Mar 2020 → Dec 2026 expected | — | Naveen Poonai | Recruiting | No outcome recorded |
| Phase 2/3 | NCT04971759 | Dec 2019 → Dec 2020 | — | Assiut University | Completed | No outcome recorded |
| Phase 2/3 | NCT04115449 | Nov 2019 → May 2021 | — | Theodor Bilharz Research Institute | Unknown | No outcome recorded |
| Phase 2/3 | NCT04237532 | Aug 2019 → Aug 2020 | — | Nourhan M.Aly | Completed | No outcome recorded |
| Phase 2/3 | NCT04042727 | Aug 2019 → Dec 2021 | atrial fibrillation | Stony Brook University | Terminated | No outcome recorded |
| Phase 2/3 | NCT04968392 | Mar 2019 → Feb 2020 | — | Assiut University | Completed | No outcome recorded |
| Phase 2/3 | NCT02856594 | Mar 2017 → Feb 2022 | delirium | Massachusetts General Hospital | Completed | No outcome recorded |
| Phase 2/3 | NCT02819141 | Nov 2016 → Oct 2024 | anxiety, respiratory failure | Mayo Clinic | Completed | No outcome recorded |
| Phase 2/3 | NCT03936205 | Aug 2016 → Oct 2017 | metastatic malignant neoplasm | Hotel Dieu de France Hospital | Completed | No outcome recorded |
| Phase 2/3 | NCT02854904 | Aug → Nov 2016 | osteoarthritis, spine, spondylolisthesis, spondylolysis | Sarah Network of Rehabilitation Hospitals | Unknown | No outcome recorded |
| Phase 2/3 | NCT02713191 | Mar 2016 → Feb 2017 | — | Post Graduate Institute of Medical Education and Research, Chandigarh | Completed | No outcome recorded |
| Phase 2/3 | NCT02495220 | Jul 2015 → Nov 2017 | — | Assiut University | Unknown | No outcome recorded |
| Phase 2/3 | NCT01733043 | Mar → May 2015 | obstructive sleep apnea syndrome | Duke University | Withdrawn | No outcome recorded |
| Phase 2/3 | NCT02237495 | Apr 2014 → Mar 2017 | coronary artery disorder, heart valve disorder | Xijing Hospital | Completed | No outcome recorded |
| Phase 2/3 | NCT01508455 | Mar → May 2012 | — | Pfizer | Completed | No outcome recorded |
| Phase 2/3 | NCT01314209 | Mar 2011 → Mar 2014 | acute kidney injury | Helsinki University Central Hospital | Unknown | No outcome recorded |
| Phase 2/3 | NCT01188551 | Jan 2011 → Apr 2012 | chronic otitis media | Nationwide Children's Hospital | Completed | No outcome recorded |
| Phase 2/3 | NCT01159262 | Jul 2010 → Aug 2011 | — | Pfizer | Completed | No outcome recorded |
| Phase 2/3 | NCT01072643 | Mar 2010 → Mar 2013 | pulmonary hypertension | Aruna Nathan | Terminated | No outcome recorded |
| Phase 2/3 | NCT00815893 | Aug 2008 → Aug 2009 | — | Kaohsiung Medical University Chung-Ho Memorial Hospital | Unknown | No outcome recorded |
| Phase 2/3 | NCT00608231 | Jan 2008 → Jan 2012 | Parkinson disease, dystonic disorder, essential tremor | Vanderbilt University | Withdrawn | No outcome recorded |
| Phase 2/3 | NCT00714857 | Oct 2007 → Dec 2010 | — | University of Turku | Completed | No outcome recorded |
| Phase 3103 trials | ||||||
| Phase 3 | NCT07569536 | Sep 2026 → Oct 2028 expected | infectious disease with sepsis | Hospices Civils de Lyon | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07434310 | Jul 2026 → Jul 2027 expected | inflammatory bowel disease | Dr. Naveed Siddiqui | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07627906 | Jul → Dec 2026 expected | delirium | Cairo University | Recruiting | No outcome recorded |
| Phase 3 | NCT07542990 | Apr 2026 → Apr 2029 expected | delirium | University Hospital, Tours | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07327879 | Jan → Nov 2026 expected | benign shuddering attacks | Al-Azhar University | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT06878703 | Oct 2025 → Dec 2027 expected | — | Assistance Publique - Hôpitaux de Paris | Recruiting | No outcome recorded |
| Phase 3 | NCT07184801 | Oct 2025 → Oct 2026 expected | — | Post Graduate Institute of Medical Education and Research, Chandigarh | Recruiting | No outcome recorded |
| Phase 3 | NCT06259565 | Jul 2025 → Dec 2029 expected | — | St. Joseph's Healthcare Hamilton | Recruiting | No outcome recorded |
| Phase 3 | NCT06875427 | Jul 2025 → Jan 2027 expected | — | Isabella Jaramillo | Recruiting | No outcome recorded |
| Phase 3 | NCT07426081 | Jun → Nov 2025 | — | Patel Hospital, Pakistan | Completed | No outcome recorded |
| Phase 3 | NCT06619912 | Mar 2025 → Oct 2026 expected | delirium, sleep disorder | Xijing Hospital | Recruiting | No outcome recorded |
| Phase 3 | NCT07350928 | Mar 2025 → Mar 2026 overdue | breast cancer | Tianjin Medical University Cancer Institute and Hospital | Recruiting | No outcome recorded |
| Phase 3 | NCT06192615 | Jan 2025 → Oct 2027 expected | delirium | Massachusetts General Hospital | Recruiting | No outcome recorded |
| Phase 3 | NCT07557680 | Jan → Jun 2025 | hypertensive disorder | Sindh Institute of Urology and Transplantation | Completed | No outcome recorded |
| Phase 3 | NCT06665438 | Dec 2024 → Apr 2025 overdue | — | Al-Azhar University | Recruiting | No outcome recorded |
| Phase 3 | NCT06991647 | Oct → Dec 2024 | — | Indonesia University | Completed | No outcome recorded |
| Phase 3 | NCT06370442 | Jun 2024 → May 2025 | mental disorder | State University of New York - Upstate Medical University | Unknown | No outcome recorded |
| Phase 3 | NCT06281561 | May → Nov 2024 | sleep disorder | The First Affiliated Hospital of Xiamen University | Unknown | No outcome recorded |
| Phase 3 | NCT05383495 | Dec 2023 → Dec 2025 overdue | — | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | Recruiting | No outcome recorded |
| Phase 3 | NCT06139926 | Dec 2023 → Jun 2024 | colorectal cancer | First Affiliated Hospital of Chongqing Medical University | Unknown | No outcome recorded |
| Phase 3 | NCT05681572 | Apr 2023 → Oct 2027 expected | — | University Hospital, Montpellier | Recruiting | No outcome recorded |
| Phase 3 | NCT05634148 | Dec 2022 → Apr 2023 | delirium | Security Forces Hospital | Completed | No outcome recorded |
| Phase 3 | NCT05665088 | Dec 2022 → Sep 2023 | dementia | BioXcel Therapeutics Inc | Terminated | No outcome recorded |
| Phase 3 | NCT05439005 | Dec 2022 → Jun 2027 expected | breast cancer | Institut Curie | Recruiting | No outcome recorded |
| Phase 3 | NCT05641064 | Nov 2022 → Sep 2024 | aortic valve stenosis | University Hospital Dubrava | Completed | No outcome recorded |
| Phase 3 | NCT05658510 | Nov 2022 → Aug 2025 | bipolar I disorder, bipolar II disorder, schizoaffective disorder, schizophrenia +1 | BioXcel Therapeutics Inc | Completed | No outcome recorded |
| Phase 3 | NCT05615727 | Sep 2022 → Sep 2023 | insomnia | The University of Hong Kong | Unknown | No outcome recorded |
| Phase 3 | NCT05481281 | Aug 2022 → Jan 2023 | — | Hamdard University | Unknown | No outcome recorded |
| Phase 3 | NCT05493228 | May 2022 → Apr 2023 | spinal cord cancer | Children's Cancer Hospital Egypt 57357 | Unknown | No outcome recorded |
| Phase 3 | NCT05311722 | Apr → Dec 2022 | — | Sheikh Zayed Medical College | Unknown | No outcome recorded |
| Phase 3 | NCT05271552 | Apr 2022 → Apr 2023 | dementia | BioXcel Therapeutics Inc | Completed | No outcome recorded |
| Phase 3 | NCT05485519 | Apr 2022 → May 2024 | substance withdrawal syndrome | King Abdullah International Medical Research Center | Unknown | No outcome recorded |
| Phase 3 | NCT05489900 | Apr → Jul 2022 | — | Federal University of Rio de Janeiro | Unknown | No outcome recorded |
| Phase 3 | NCT05099055 | Mar 2022 → Jan 2023 | — | St. Justine's Hospital | Completed | No outcome recorded |
| Phase 3 | NCT05192629 | Mar 2022 → Jun 2023 | — | Brugmann University Hospital | Unknown | No outcome recorded |
| Phase 3 | NCT04878510 | Mar 2022 → Apr 2024 | respiratory failure | St. Joseph's Healthcare Hamilton | Completed | No outcome recorded |
| Phase 3 | NCT05849597 | Mar 2022 → Feb 2025 overdue | delirium | University of Novi Sad | Recruiting | No outcome recorded |
| Phase 3 | NCT05233683 | Mar 2022 → Mar 2023 | childhood acute lymphoblastic leukemia | King Saud University | Unknown | No outcome recorded |
| Phase 3 | NCT05072704 | Feb 2022 → Feb 2023 | — | CMC Ambroise Paré | Completed | No outcome recorded |
| Phase 3 | NCT05191745 | Jan 2022 → Apr 2023 | — | Jewish General Hospital | Completed | No outcome recorded |
| Phase 3 | NCT05111431 | Nov 2021 → May 2022 | — | Shanghai Hengrui Pharmaceutical Co., Ltd. | Completed | No outcome recorded |
| Phase 3 | NCT04955158 | Aug 2021 → Feb 2023 | pharyngitis | Assiut University | Completed | No outcome recorded |
| Phase 3 | NCT04940689 | Jul 2021 → Aug 2024 | — | University Hospital, Rouen | Completed | No outcome recorded |
| Phase 3 | NCT04941508 | Jun → Nov 2021 | — | Assiut University | Completed | No outcome recorded |
| Phase 3 | NCT04928391 | Jun 2021 → Mar 2026 | cleft palate | Assiut University | Completed | No outcome recorded |
| Phase 3 | NCT04928300 | Jun 2021 → Jul 2027 expected | — | Assiut University | Recruiting | No outcome recorded |
| Phase 3 | NCT04621110 | Jun → Sep 2021 | childhood malignant neoplasm | University of Sao Paulo General Hospital | Unknown | No outcome recorded |
| Phase 3 | NCT04910477 | Jun → Sep 2021 | headache disorder | Assiut University | Completed | No outcome recorded |
| Phase 3 | NCT04144933 | May 2021 → Jul 2024 | paralytic ileus | University of Saskatchewan | Unknown | No outcome recorded |
| Phase 3 | NCT04576975 | Apr → Dec 2021 | morbid obesity | Ain Shams University | Unknown | No outcome recorded |
| Phase 3 | NCT04709315 | Oct 2020 → Jan 2021 | — | South Valley University | Unknown | No outcome recorded |
| Phase 3 | NCT04276883 | Feb → May 2020 | bipolar disorder | BioXcel Therapeutics Inc | Completed | No outcome recorded |
| Phase 3 | NCT04197570 | Feb → Mar 2020 | substance-related disorder | Benaroya Research Institute | Completed | No outcome recorded |
| Phase 3 | NCT04268303 | Jan → May 2020 | schizoaffective disorder, schizophrenia, schizophreniform disorder | BioXcel Therapeutics Inc | Completed | No outcome recorded |
| Phase 3 | NCT04081545 | Dec 2019 → Mar 2023 | substance-related disorder | Christine Oryhan | Completed | No outcome recorded |
| Phase 3 | NCT03953677 | Oct 2019 → Jan 2023 | infectious disease with sepsis | Centre Hospitalier Universitaire Dijon | Terminated | No outcome recorded |
| Phase 3 | NCT06185127 | Sep 2019 → May 2020 | lung disorder | University of Patras | Completed | No outcome recorded |
| Phase 3 | NCT03834129 | May 2019 → Jan 2020 | — | CMC Ambroise Paré | Completed | No outcome recorded |
| Phase 3 | NCT03530371 | May 2019 → Nov 2021 | — | Fondation Lenval | Completed | No outcome recorded |
| Phase 3 | NCT03653832 | Dec 2018 → Dec 2023 | — | University of Edinburgh | Completed | No outcome recorded |
| Phase 3 | NCT03151863 | Nov 2018 → Jun 2021 | — | Walid HABRE | Terminated | No outcome recorded |
| Phase 3 | NCT03640390 | Aug 2018 → Aug 2019 | — | Cairo University | Completed | No outcome recorded |
| Phase 3 | NCT03524950 | Jun 2018 → Dec 2019 | leiomyoma | Beijing Anzhen Hospital | Unknown | No outcome recorded |
| Phase 3 | NCT04276545 | Jan 2018 → Mar 2020 | hemorrhagic disease | Eye & ENT Hospital of Fudan University | Completed | No outcome recorded |
| Phase 3 | NCT03317067 | Dec 2017 → May 2021 | delirium | University Hospital, Clermont-Ferrand | Completed | No outcome recorded |
| Phase 3 | NCT03316339 | Nov 2017 → Jan 2019 | substance-related disorder | Rennes University Hospital | Terminated | No outcome recorded |
| Phase 3 | NCT03089905 | Aug 2017 → Mar 2026 overdue | poisoning | Murdoch Childrens Research Institute | Active not recruiting | No outcome recorded |
| Phase 3 | NCT03115047 | May 2017 → Aug 2020 | — | University of Montreal Hospital Centre (CHUM) | Completed | No outcome recorded |
| Phase 3 | NCT03117023 | Apr → May 2017 | gastric cancer | Nanjing PLA General Hospital | Unknown | No outcome recorded |
| Phase 3 | NCT03151668 | Jan 2017 → Mar 2018 | infectious disease with sepsis | Cairo University | Unknown | No outcome recorded |
| Phase 3 | NCT02752477 | Aug 2016 → Sep 2020 | chronic pain syndrome | Ben Lim | Unknown | No outcome recorded |
| Phase 3 | NCT02757625 | Jul 2016 → May 2017 | — | Pfizer | Completed | No outcome recorded |
| Phase 3 | NCT02787018 | Jun 2016 → Sep 2018 | — | B.P. Koirala Institute of Health Sciences | Completed | No outcome recorded |
| Phase 3 | NCT02880540 | Mar 2016 → Feb 2018 | obesity disorder | Janelle Vaughns | Completed | No outcome recorded |
| Phase 3 | NCT02638545 | Sep 2015 → Jan 2017 | infectious disease with sepsis | University of Roma La Sapienza | Completed | No outcome recorded |
| Phase 3 | NCT02512809 | Jul 2015 → Oct 2017 | hydrocephalus, poisoning | Nationwide Children's Hospital | Terminated | No outcome recorded |
| Phase 3 | NCT02559102 | Jul 2015 → Jul 2020 | hernia, double inguinal, neurodevelopmental disorder | KK Women's and Children's Hospital | Completed | No outcome recorded |
| Phase 3 | NCT02466022 | Jun → Nov 2015 | — | University of Saskatchewan | Completed | No outcome recorded |
| Phase 3 | NCT02250703 | Sep 2014 → Sep 2016 | — | University of Mississippi Medical Center | Completed | No outcome recorded |
| Phase 3 | NCT02540070 | Aug 2014 → Dec 2017 | osteoarthritis, knee | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | Unknown | No outcome recorded |
| Phase 3 | NCT02282787 | Jan 2014 → Jan 2015 | — | King Saud University | Unknown | No outcome recorded |
| Phase 3 | NCT01973452 | Oct 2013 → Dec 2022 | — | Memorial Sloan Kettering Cancer Center | Completed | No outcome recorded |
| Phase 3 | NCT01283412 | Jun 2013 → Jun 2014 | delirium | Huazhong University of Science and Technology | Unknown | No outcome recorded |
| Phase 3 | NCT01557270 | Mar → Nov 2012 | — | Prof. Peter Gerner, M.D. | Completed | No outcome recorded |
| Phase 3 | NCT01565590 | Feb 2012 → Jul 2015 | acquired aneurysmal subarachnoid hemorrhage | University of Cincinnati | Terminated | No outcome recorded |
| Phase 3 | NCT01266252 | Jul 2011 → Apr 2017 | neonatal respiratory failure | University Hospital, Ghent | Completed | No outcome recorded |
| Phase 3 | NCT01438957 | Jun → Nov 2011 | — | Pfizer | Completed | No outcome recorded |
| Phase 3 | NCT01140529 | May 2010 → May 2012 | delirium | Thorax-Kärlkliniken | Terminated | No outcome recorded |
| Phase 3 | NCT01091818 | Mar 2010 → Oct 2011 | — | Ullevaal University Hospital | Unknown | No outcome recorded |
| Phase 3 | NCT01076816 | Dec 2009 → Feb 2011 | respiratory failure | University Hospital, Ghent | Terminated | No outcome recorded |
| Phase 3 | NCT01083797 | Dec 2009 → Mar 2013 | brain disorder | Federal University of Minas Gerais | Completed | No outcome recorded |
| Phase 3 | NCT00857727 | Aug 2009 → Nov 2011 | — | St. Luke's-Roosevelt Hospital Center | Completed | No outcome recorded |
| Phase 3 | NCT00921284 | Jun 2009 → Jul 2011 | — | Hopital Foch | Completed | No outcome recorded |
| Phase 3 | NCT00926705 | Jun 2008 → Jan 2009 | — | University of Jordan | Completed | No outcome recorded |
| Phase 3 | NCT00526760 | Oct 2007 → Jun 2008 | — | Pfizer | Completed | No outcome recorded |
| Phase 3 | NCT00479661 | May 2007 → Mar 2010 | — | Orion Corporation, Orion Pharma | Completed | No outcome recorded |
| Phase 3 | NCT00460473 | Apr → Nov 2007 | delirium | Pfizer | Terminated | No outcome recorded |
| Phase 3 | NCT00464763 | Apr → Sep 2007 | delirium | Pfizer | Withdrawn | No outcome recorded |
| Phase 3 | NCT00468052 | Mar 2007 → May 2008 | obstructive sleep apnea syndrome | University of Medicine and Dentistry of New Jersey | Completed | No outcome recorded |
| Phase 3 | NCT00398827 | Dec 2006 → May 2007 | — | Pfizer | Completed | No outcome recorded |
| Phase 3 | NCT00480740 | Dec 2006 → Oct 2011 | atrial septal defect, patent ductus arteriosus | Children's National Research Institute | Completed | No outcome recorded |
| Phase 3 | NCT00383890 | Aug 2006 → Jan 2007 | — | Pfizer | Completed | No outcome recorded |
| Phase 3 | NCT00226785 | Oct 2005 → Jul 2006 | — | Orion Corporation, Orion Pharma | Terminated | No outcome recorded |
| Phase 4398 trials | ||||||
| Phase 4 | NCT07597109 | Sep 2026 expected | arterial disorder | Insel Gruppe AG, University Hospital Bern | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07644663 | Jun → Aug 2026 overdue | — | Fudan University | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07570160 | Jun 2026 → Nov 2027 expected | — | Nanjing Children's Hospital | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07306702 | Jun 2026 → May 2027 | — | Shenyang Sixth People's Hospital | Withdrawn | No outcome recorded |
| Phase 4 | NCT07579806 | Jun → Dec 2026 expected | delirium | Sichuan Provincial People's Hospital | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07576517 | Jun 2026 → Jun 2029 expected | cognitive disorder | Peking University First Hospital | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07567495 | Jun 2026 → May 2028 expected | — | Columbia University | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07639099 | Jun 2026 → Oct 2029 expected | postpartum depression | Peking University First Hospital | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07610343 | Jun 2026 → Nov 2027 expected | cognitive impairment with or without cerebellar ataxia, sleep disorder | Peking University First Hospital | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07576543 | Jun 2026 → Jun 2030 expected | cognitive disorder | Peking University First Hospital | Not yet recruiting | No outcome recorded |
| Show all 398 trials opens the full record — a long page | ||||||
| Phase not applicable357 trials | ||||||
| — | NCT07657715 | Aug 2026 → Dec 2027 expected | infectious disease with sepsis | First Affiliated Hospital of Wannan Medical College | Not yet recruiting | No outcome recorded |
| — | NCT07695220 | Jul 2026 → Oct 2028 expected | intracerebral hemorrhage | The Third Affiliated Hospital of Southern Medical University | Not yet recruiting | No outcome recorded |
| — | NCT07677215 | Jul 2026 → Sep 2027 expected | osteoarthritis, knee | Poznan University of Medical Sciences | Not yet recruiting | No outcome recorded |
| — | NCT07678216 | Jul 2026 → Jun 2028 expected | traumatic brain injury | Aswan University | Not yet recruiting | No outcome recorded |
| — | NCT07699523 | Jun 2026 → Jun 2027 expected | electroencephalographic peculiarity: fronto-precentral beta wave groups | China-Japan Friendship Hospital | Not yet recruiting | No outcome recorded |
| — | NCT07636070 | Jun → Aug 2026 overdue | urolithiasis | murat sahin | Not yet recruiting | No outcome recorded |
| — | NCT07675616 | May → Dec 2026 expected | lacrimal duct obstruction | Cairo University | Recruiting | No outcome recorded |
| — | NCT07565116 | May → Aug 2026 overdue | — | Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital | Recruiting | No outcome recorded |
| — | NCT07501221 | May 2026 → Jun 2027 expected | — | Chengdu Jinjiang Maternity and Child Health Hospital | Not yet recruiting | No outcome recorded |
| — | NCT07501728 | May 2026 → Jan 2027 expected | postpartum depression | Chengdu Jinjiang Maternity and Child Health Hospital | Not yet recruiting | No outcome recorded |
| Show all 357 trials opens the full record — a long page | ||||||
Also used as a comparator or background therapy in 730 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 018 trials | ||||||
| Phase 0 | NCT07485127 Comparator | Feb → Aug 2026 overdue | — | Sohag University | Active not recruiting | No outcome recorded |
| Phase 0 | NCT07012213 Comparator | Oct → Nov 2025 overdue | — | Cairo University | Not yet recruiting | No outcome recorded |
| Phase 0 | NCT06741566 Comparator | Dec 2024 → May 2026 overdue | — | Minia University | Recruiting | No outcome recorded |
| Phase 0 | NCT06607861 Comparator | Jun 2024 → Jun 2026 overdue | — | Minia University | Recruiting | No outcome recorded |
| Phase 0 | NCT05829148 Comparator | May 2023 → Nov 2024 | — | Egymedicalpedia | Unknown | No outcome recorded |
| Phase 0 | NCT05778305 Comparator | Jan → Dec 2023 | — | Ain Shams University | Completed | No outcome recorded |
| Phase 0 | NCT06501352 Comparator | Jan 2023 → Mar 2024 | — | Ain Shams University | Completed | No outcome recorded |
| Phase 0 | NCT05674253 Comparator | Dec 2022 → Jun 2023 | atrial fibrillation | Ain Shams University | Unknown | No outcome recorded |
| Phase 0 | NCT05577117 Comparator | Sep → Nov 2022 | peripheral nerve lesion | Cairo University | Completed | No outcome recorded |
| Phase 0 | NCT05242692 Comparator | Jun 2022 → Aug 2025 | delirium | Affiliated Cancer Hospital & Institute of Guangzhou Medical University | Completed | No outcome recorded |
| Phase 0 | NCT05370963 Comparator | May 2022 → May 2023 | chronic pain syndrome | Minia University | Completed | No outcome recorded |
| Phase 0 | NCT05349448 Comparator | Mar → Nov 2022 | neuropathy, painful | Minia University | Unknown | No outcome recorded |
| Phase 0 | NCT04659642 Comparator | Nov 2020 → Mar 2021 | reactive airway disease, vascular hemostatic disease | National Cancer Institute, Egypt | Unknown | No outcome recorded |
| Phase 0 | NCT04498351 Comparator | Jun 2020 → Sep 2021 | — | Cairo University | Completed | No outcome recorded |
| Phase 0 | NCT04016740 Background | Aug 2019 → Feb 2020 | coronary artery disorder, delirium | Beth Israel Deaconess Medical Center | Completed | No outcome recorded |
| Phase 0 | NCT04018157 Comparator | Jul → Nov 2019 | — | Zagazig University | Completed | No outcome recorded |
| Phase 0 | NCT03885804 Comparator | Mar → Jul 2019 | — | Ain Shams University | Completed | No outcome recorded |
| Phase 0 | NCT03746418 Comparator | Jan 2016 → Jan 2018 | spondylolisthesis | Tanta University | Completed | No outcome recorded |
| Phase 134 trials | ||||||
| Phase 1 | NCT07380139 Comparator | Feb → Dec 2026 expected | — | Ain Shams University | Enrolling by invitation | No outcome recorded |
| Phase 1 | NCT07279727 Comparator | Jan → Dec 2026 expected | — | Assiut University | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT07332130 Comparator | Dec 2025 → Jan 2026 overdue | — | Minia University Hospital | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT06958367 Comparator | Nov 2025 → Nov 2026 expected | — | Ain Shams University | Active not recruiting | No outcome recorded |
| Phase 1 | NCT07669012 Comparator | Oct 2025 → Oct 2026 expected | — | Ain Shams University | Recruiting | No outcome recorded |
| Phase 1 | NCT07086690 Comparator | Apr 2025 → Apr 2027 expected | — | Ain Shams University | Active not recruiting | No outcome recorded |
| Phase 1 | NCT07072650 Comparator | Jan → May 2025 | — | Majid Fakhir Mutar Alhamaaidah | Completed | No outcome recorded |
| Phase 1 | NCT07149168 Comparator | Dec 2024 → Jun 2025 | — | Ain Shams University | Completed | No outcome recorded |
| Phase 1 | NCT06702488 Comparator | Nov 2024 → Apr 2025 overdue | mental disorder | Fayoum University | Recruiting | No outcome recorded |
| Phase 1 | NCT06668220 Comparator | Nov 2024 → Oct 2026 expected | — | Assiut University | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT06808295 Comparator | Apr 2024 → Apr 2025 overdue | nasolacrimal duct disorder | Research Institute of Ophthalmology, Egypt | Recruiting | No outcome recorded |
| Phase 1 | NCT06653244 Comparator | Apr → Dec 2024 | — | Menoufia University | Completed | No outcome recorded |
| Phase 1 | NCT06318546 Comparator | Apr → Aug 2024 | benign shuddering attacks | Ain Shams University | Completed | No outcome recorded |
| Phase 1 | NCT06294665 Comparator | Mar → Dec 2024 | — | Ain Shams University | Unknown | No outcome recorded |
| Phase 1 | NCT06502262 Comparator | Jan → Aug 2024 | — | Ain Shams University | Completed | No outcome recorded |
| Phase 1 | NCT05903963 Comparator | May → Nov 2023 | kidney failure | Minia University | Unknown | No outcome recorded |
| Phase 1 | NCT04942340 Comparator | May 2023 → Apr 2026 | — | University of Chicago | Withdrawn | No outcome recorded |
| Phase 1 | NCT05828199 Comparator | Dec 2022 → Dec 2023 | nasal cavity polyp, nose, anomalous shape of | Al-Azhar University | Unknown | No outcome recorded |
| Phase 1 | NCT05872087 Comparator | Nov 2022 → Sep 2023 | delirium | Ain Shams University | Completed | No outcome recorded |
| Phase 1 | NCT05591001 Comparator | Oct 2022 → Mar 2023 | tethered spinal cord syndrome | Cairo University | Completed | No outcome recorded |
| Phase 1 | NCT05337085 Comparator | Jun → Dec 2022 | — | Sheikh Zayed Medical College | Unknown | No outcome recorded |
| Phase 1 | NCT05487742 Comparator | Jun → Dec 2022 | — | Tanta University | Unknown | No outcome recorded |
| Phase 1 | NCT05320705 Comparator | Apr → Sep 2022 | atrial fibrillation | Kasr El Aini Hospital | Unknown | No outcome recorded |
| Phase 1 | NCT05314569 Comparator | Apr → Sep 2022 | — | Cairo University | Completed | No outcome recorded |
| Phase 1 | NCT05119101 Comparator | Mar 2022 → Oct 2023 | preeclampsia | Assiut University | Unknown | No outcome recorded |
| Phase 1 | NCT05402189 Comparator | Feb → Jun 2022 | — | Ain Shams University | Unknown | No outcome recorded |
| Phase 1 | NCT04678050 Comparator | Oct 2020 → Dec 2021 | — | Ain Shams University | Completed | No outcome recorded |
| Phase 1 | NCT03708315 Comparator | Mar 2020 → May 2023 | schizoaffective disorder, schizophrenia | Yale University | Completed | No outcome recorded |
| Phase 1 | NCT03938857 Comparator | Jul 2019 → Oct 2020 | — | Duke University | Terminated | No outcome recorded |
| Phase 1 | NCT03261921 Comparator | Jun 2016 → Jun 2017 | — | Cairo University | Completed | No outcome recorded |
| Phase 1 | NCT02715154 Comparator | Jun → Nov 2015 | — | The First Affiliated Hospital with Nanjing Medical University | Completed | No outcome recorded |
| Phase 1 | NCT01005433 Comparator | Dec 2009 → Oct 2011 | — | King Faisal University | Completed | No outcome recorded |
| Phase 1 | NCT00894751 Comparator | Jan 2009 → Jan 2011 | — | Children's Hospital Medical Center, Cincinnati | Terminated | No outcome recorded |
| Phase 1 | NCT00671931 Comparator | Apr 2007 → Jan 2009 | scoliosis | Children's Hospital Medical Center, Cincinnati | Completed | No outcome recorded |
| Phase 1/220 trials | ||||||
| Phase 1/2 | NCT06490731 Comparator | Apr → Jun 2026 overdue | — | New Valley University | Recruiting | No outcome recorded |
| Phase 1/2 | NCT07180095 Comparator | Jan → Jun 2026 overdue | — | Liaquat National Hospital & Medical College | Not yet recruiting | No outcome recorded |
| Phase 1/2 | NCT07101367 Comparator | Sep 2025 → Aug 2026 overdue | autoinflammatory syndrome, coronary artery disorder | Ain Shams University | Not yet recruiting | No outcome recorded |
| Phase 1/2 | NCT07432997 Comparator | Dec 2023 → Sep 2024 | Alzheimer disease | Applied Cognition | Completed | No outcome recorded |
| Phase 1/2 | NCT06077539 Comparator | Sep 2023 → Apr 2024 | subacute delirium | Cairo University | Unknown | No outcome recorded |
| Phase 1/2 | NCT05590234 Comparator | Nov 2022 → Jul 2023 | — | October 6 University | Completed | No outcome recorded |
| Phase 1/2 | NCT04621526 Comparator | Nov 2020 → Aug 2023 | — | Zagazig University | Completed | No outcome recorded |
| Phase 1/2 | NCT04535089 Comparator | Oct 2020 → Oct 2021 | — | Zagazig University | Completed | No outcome recorded |
| Phase 1/2 | NCT04251910 Comparator | Dec 2019 → Jan 2022 | dementia | BioXcel Therapeutics Inc | Completed | No outcome recorded |
| Phase 1/2 | NCT04113720 Comparator | Nov 2019 → Oct 2020 | — | Assiut University | Completed | No outcome recorded |
| Phase 1/2 | NCT03892512 Comparator | Apr → Dec 2019 | cognitive disorder | Beni-Suef University | Unknown | No outcome recorded |
| Phase 1/2 | NCT04058899 Comparator | Mar → Sep 2019 | delirium | Ain Shams University | Unknown | No outcome recorded |
| Phase 1/2 | NCT03778671 Comparator | Jan → Nov 2019 | — | Assiut University | Completed | No outcome recorded |
| Phase 1/2 | NCT03762785 Comparator | Dec 2018 → Jan 2020 | digestive system cancer | Assiut University | Unknown | No outcome recorded |
| Phase 1/2 | NCT03024957 Comparator | Jan 2017 → Sep 2018 | immunodeficiency disease | Assiut University | Unknown | No outcome recorded |
| Phase 1/2 | NCT02935959 Comparator | Oct 2016 → Sep 2017 | childhood malignant neoplasm | Assiut University | Completed | No outcome recorded |
| Phase 1/2 | NCT02935933 Comparator | Oct 2016 → Sep 2017 | chronic pain syndrome | Assiut University | Unknown | No outcome recorded |
| Phase 1/2 | NCT02031510 Comparator | Jan 2014 → Feb 2015 | — | Imam Abdulrahman Bin Faisal University | Completed | No outcome recorded |
| Phase 1/2 | NCT00345384 Comparator | May 2008 → Jan 2010 | respiratory underresponsiveness to hypoxia and hypercapnia | Baylor Research Institute | Completed | No outcome recorded |
| Phase 1/2 | NCT00538616 Comparator | Jan → Feb 2008 | brain injury | Carmelo Graffagnino | Completed | No outcome recorded |
| Phase 251 trials | ||||||
| Phase 2 | NCT07550881 Comparator | Apr → Dec 2026 expected | anxiety | Tongji University | Recruiting | No outcome recorded |
| Phase 2 | NCT07465185 Comparator | Mar → Sep 2026 expected | — | Benha University | Recruiting | No outcome recorded |
| Phase 2 | NCT07443085 Comparator | Feb 2026 → Jul 2027 expected | delirium | Benha University | Recruiting | No outcome recorded |
| Phase 2 | NCT06052254 Comparator | Sep 2025 → May 2027 expected | — | Teikoku Pharma USA, Inc. | Recruiting | No outcome recorded |
| Phase 2 | NCT06936410 Comparator | Mar 2025 → Mar 2026 | — | Cairo University | Completed | No outcome recorded |
| Phase 2 | NCT06736392 Comparator | Mar 2025 → Aug 2026 overdue | — | Assiut University | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT07510217 Comparator | Aug 2024 → Dec 2025 | — | Tanta University | Completed | No outcome recorded |
| Phase 2 | NCT06327399 Comparator | Apr → Aug 2024 | — | Kasr El Aini Hospital | Completed | No outcome recorded |
| Phase 2 | NCT06711913 Comparator | Dec 2023 → Jun 2024 | benign shuddering attacks | Liaquat National Hospital & Medical College | Completed | No outcome recorded |
| Phase 2 | NCT06096181 Comparator | Dec 2023 → Dec 2024 | adolescent idiopathic scoliosis | Cedars-Sinai Medical Center | Terminated | No outcome recorded |
| Phase 2 | NCT05692167 Comparator | Jul → Oct 2023 | cataract | Kafrelsheikh University | Unknown | No outcome recorded |
| Phase 2 | NCT06183073 Comparator | Apr 2023 → Jan 2024 | — | Sohag University | Unknown | No outcome recorded |
| Phase 2 | NCT06017167 Comparator | Sep 2022 → Sep 2023 | gallbladder disorder | Tanta University | Unknown | No outcome recorded |
| Phase 2 | NCT05412992 Comparator | Jul 2022 → Apr 2023 | — | Teikoku Pharma USA, Inc. | Terminated | No outcome recorded |
| Phase 2 | NCT05327088 Comparator | Sep 2021 → Feb 2022 | — | Ain Shams University | Completed | No outcome recorded |
| Phase 2 | NCT05005715 Comparator | Aug 2021 → Aug 2022 | non-functioning pituitary adenoma | Seoul National University Hospital | Unknown | No outcome recorded |
| Phase 2 | NCT04715165 Comparator | Aug 2021 → Feb 2022 | — | Assiut University | Unknown | No outcome recorded |
| Phase 2 | NCT04949477 Comparator | Jul → Dec 2021 | anxiety | Benha University | Completed | No outcome recorded |
| Phase 2 | NCT04724759 Background | Jun 2021 → Apr 2023 | temporomandibular joint disorder | Massachusetts General Hospital | Completed | No outcome recorded |
| Phase 2 | NCT04892420 Comparator | Jun → Aug 2021 | — | Ain Shams University | Completed | No outcome recorded |
| Phase 2 | NCT04873596 Comparator | May 2021 → Jun 2024 | — | Zagazig University | Unknown | No outcome recorded |
| Phase 2 | NCT04730375 Comparator | Jan 2021 → Feb 2022 | obesity disorder | National Cancer Institute, Egypt | Completed | No outcome recorded |
| Phase 2 | NCT04526652 Comparator | Dec 2020 → Jul 2021 | anxiety disorder | Universiti Sains Malaysia | Completed | No outcome recorded |
| Phase 2 | NCT04242407 Comparator | Jul 2020 → Feb 2021 | neuropathy, painful | Teikoku Pharma USA, Inc. | Unknown | No outcome recorded |
| Phase 2 | NCT04149626 Comparator | Jan 2020 → Dec 2021 | — | Asklepieion Voulas General Hospital | Unknown | No outcome recorded |
| Phase 2 | NCT03714919 Background | Aug → Nov 2019 | adenoid hypertrophy | Arlyne Thung | Completed | No outcome recorded |
| Phase 2 | NCT03933280 Comparator | Jul 2019 → Dec 2020 | — | Menoufia University | Completed | No outcome recorded |
| Phase 2 | NCT04320589 Comparator | Jun 2019 → Aug 2021 | pheochromocytoma | National Cancer Institute, Egypt | Completed | No outcome recorded |
| Phase 2 | NCT03925779 Comparator | Jun 2019 → Dec 2020 | — | Menoufia University | Completed | No outcome recorded |
| Phase 2 | NCT03735368 Comparator | Dec 2018 → Oct 2019 | — | Abd-Elazeem Abd-Elhameed Elbakry | Completed | No outcome recorded |
| Phase 2 | NCT03355053 Comparator | May 2018 → Apr 2022 | delirium | Massachusetts General Hospital | Completed | No outcome recorded |
| Phase 2 | NCT03412474 Comparator | Jan → Aug 2018 | cleft palate | Assiut University | Completed | No outcome recorded |
| Phase 2 | NCT03156296 Comparator | Jun 2017 → Aug 2018 | — | Assiut University | Completed | No outcome recorded |
| Phase 2 | NCT03163238 Comparator | May 2017 → Oct 2018 | — | Assiut University | Unknown | No outcome recorded |
| Phase 2 | NCT02953054 Comparator | Jan → Jul 2017 | neuropathy, painful | Teikoku Pharma USA, Inc. | Completed | No outcome recorded |
| Phase 2 | NCT02886429 Comparator | Aug 2016 → Aug 2018 | neuropathy, painful | Assiut University | Completed | No outcome recorded |
| Phase 2 | NCT02820610 Comparator | Aug 2016 → Sep 2019 | — | Assiut University | Completed | No outcome recorded |
| Phase 2 | NCT02861716 Comparator | Aug 2016 → Feb 2019 | childhood malignant neoplasm | South Egypt Cancer Institute | Unknown | No outcome recorded |
| Phase 2 | NCT02818985 Comparator | Jun 2016 → Feb 2017 | — | Assiut University | Completed | No outcome recorded |
| Phase 2 | NCT02727621 Comparator | Apr → Sep 2016 | — | Assiut University | Completed | No outcome recorded |
| Phase 2 | NCT05324891 Comparator | Jan 2016 → Aug 2017 | — | Mansoura University | Completed | No outcome recorded |
| Phase 2 | NCT02397603 Comparator | Feb → Nov 2015 | — | Cairo University | Completed | No outcome recorded |
| Phase 2 | NCT02416063 Comparator | Jan → Oct 2014 | — | University of Jordan | Completed | No outcome recorded |
| Phase 2 | NCT02382432 Comparator | Dec 2013 → Dec 2014 | — | Assiut University | Completed | No outcome recorded |
| Phase 2 | NCT01766089 Comparator | Jan 2013 → Dec 2016 | severe pre-eclampsia | Mansoura University | Completed | No outcome recorded |
| Phase 2 | NCT01505933 Comparator | Feb 2012 → Dec 2017 | — | Milton S. Hershey Medical Center | Terminated | No outcome recorded |
| Phase 2 | NCT01289769 Comparator | Mar → Dec 2011 | cardiac rhythm disease, hypertensive disorder | Chiang Mai University | Completed | No outcome recorded |
| Phase 2 | NCT00871624 Comparator | Mar 2009 → Feb 2013 | acute respiratory failure | Tufts Medical Center | Completed | No outcome recorded |
| Phase 2 | NCT00848393 Comparator | Nov 2008 → Dec 2013 | atrioventricular septal defect, tetralogy of fallot, ventricular septal defect | Nationwide Children's Hospital | Completed | No outcome recorded |
| Phase 2 | NCT00390871 Comparator | May 2005 → Dec 2007 | — | Johns Hopkins University | Completed | No outcome recorded |
| Phase 2 | NCT00095251 Comparator | Aug 2004 → Aug 2007 | delirium | Vanderbilt University | Completed | No outcome recorded |
| Phase 2/341 trials | ||||||
| Phase 2/3 | NCT06970626 Comparator | Apr → Jun 2025 overdue | — | Alexandria University | Recruiting | No outcome recorded |
| Phase 2/3 | NCT06427707 Comparator | Jun → Oct 2024 overdue | esophageal varices with bleeding | Ain Shams University | Recruiting | No outcome recorded |
| Phase 2/3 | NCT06830564 Comparator | May → Nov 2024 | delirium | Ain Shams University | Completed | No outcome recorded |
| Phase 2/3 | NCT07434206 Comparator | Apr 2024 → Mar 2026 overdue | thyroid tumor | South Egypt Cancer Institute | Active not recruiting | No outcome recorded |
| Phase 2/3 | NCT06082076 Comparator | Nov 2023 → Nov 2024 | — | Assiut University | Unknown | No outcome recorded |
| Phase 2/3 | NCT06046105 Comparator | Sep 2023 → Mar 2024 | — | Ain Shams University | Unknown | No outcome recorded |
| Phase 2/3 | NCT05705128 Comparator | Aug 2023 → May 2025 overdue | — | New Valley University | Enrolling by invitation | No outcome recorded |
| Phase 2/3 | NCT05781854 Comparator | May 2023 → Mar 2025 | — | Assiut University | Unknown | No outcome recorded |
| Phase 2/3 | NCT07385040 Comparator | Apr → Dec 2023 | cardiac rhythm disease, hypertensive disorder | Shaheed Mohtarma Benazir Bhutto Institue of Trauma | Completed | No outcome recorded |
| Phase 2/3 | NCT05727098 Comparator | Jan → Apr 2023 | breast cancer | National Cancer Institute, Egypt | Completed | No outcome recorded |
| Phase 2/3 | NCT06756971 Comparator | Jun 2022 → Nov 2023 | sleep apnea syndrome | University of Iowa | Withdrawn | No outcome recorded |
| Phase 2/3 | NCT05340725 Comparator | May 2022 → Dec 2023 | — | Assiut University | Unknown | No outcome recorded |
| Phase 2/3 | NCT05636566 Comparator | Feb → Sep 2022 | childhood malignant neoplasm, invasive carcinoma | Alexandria University | Completed | No outcome recorded |
| Phase 2/3 | NCT06654531 Comparator | Jan 2022 → Dec 2023 | — | Al-Azhar University | Completed | No outcome recorded |
| Phase 2/3 | NCT05194904 Comparator | Jan 2022 → Jul 2023 | — | Assiut University | Unknown | No outcome recorded |
| Phase 2/3 | NCT05271253 Comparator | Apr → Nov 2021 | acute kidney injury | Alexandria University | Completed | No outcome recorded |
| Phase 2/3 | NCT04813016 Comparator | Mar 2021 → Apr 2022 | — | National Cancer Institute, Egypt | Completed | No outcome recorded |
| Phase 2/3 | NCT05446623 Comparator | Jan 2021 → Oct 2024 | arthropathy | Centre Hospitalier de Montauban | Completed | No outcome recorded |
| Phase 2/3 | NCT04704622 Comparator | Jan → Feb 2021 | — | Ain Shams University | Completed | No outcome recorded |
| Phase 2/3 | NCT04385602 Comparator | Jun 2020 → Oct 2022 | — | Assiut University | Completed | No outcome recorded |
| Phase 2/3 | NCT03775655 Comparator | Sep 2018 → Jan 2019 | — | Menoufia University | Completed | No outcome recorded |
| Phase 2/3 | NCT03363425 Comparator | Nov 2017 → Nov 2018 | leiomyoma | University of Athens | Unknown | No outcome recorded |
| Phase 2/3 | NCT03328299 Comparator | Nov 2017 → Dec 2018 | — | Assiut University | Completed | No outcome recorded |
| Phase 2/3 | NCT03307590 Comparator | Oct → Dec 2017 | — | Cairo University | Completed | No outcome recorded |
| Phase 2/3 | NCT03285165 Comparator | Sep 2017 → Sep 2021 | — | Assiut University | Suspended | No outcome recorded |
| Phase 2/3 | NCT03212495 Comparator | Aug → Nov 2017 | osteoarthritis, knee | Assiut University | Completed | No outcome recorded |
| Phase 2/3 | NCT03391609 Comparator | Jun 2017 → Nov 2018 | mild pre-eclampsia | Assiut University | Completed | No outcome recorded |
| Phase 2/3 | NCT03155646 Comparator | Jun 2017 → Aug 2019 | — | Assiut University | Completed | No outcome recorded |
| Phase 2/3 | NCT03131375 Comparator | May → Jul 2017 | delirium | Athens General Children's Hospital "Pan. & Aglaia Kyriakou" | Completed | No outcome recorded |
| Phase 2/3 | NCT03120247 Comparator | Apr 2017 → Jun 2019 | — | Assiut University | Completed | No outcome recorded |
| Phase 2/3 | NCT03060070 Comparator | Mar → Jun 2017 | — | Assiut University | Completed | No outcome recorded |
| Phase 2/3 | NCT03063671 Comparator | Jan → Jul 2017 | — | Assiut University | Completed | No outcome recorded |
| Phase 2/3 | NCT02996058 Comparator | Dec 2016 → Mar 2018 | — | Assiut University | Completed | No outcome recorded |
| Phase 2/3 | NCT02917018 Comparator | May → Dec 2016 | — | Assiut University | Completed | No outcome recorded |
| Phase 2/3 | NCT02720705 Comparator | May 2016 → Oct 2018 | — | Assiut University | Completed | No outcome recorded |
| Phase 2/3 | NCT02606409 Comparator | Nov 2015 → Jun 2016 | — | Assiut University | Completed | No outcome recorded |
| Phase 2/3 | NCT02487355 Comparator | May 2015 → Dec 2017 | — | Assiut University | Unknown | No outcome recorded |
| Phase 2/3 | NCT02455609 Comparator | Mar → Aug 2015 | — | Assiut University | Unknown | No outcome recorded |
| Phase 2/3 | NCT02213159 Comparator | Jul 2014 → Nov 2015 | diabetes mellitus, hypertensive disorder, obesity disorder, sleep apnea syndrome | American University of Beirut Medical Center | Completed | No outcome recorded |
| Phase 2/3 | NCT02435537 Comparator | May 2013 → Mar 2015 | — | Assiut University | Completed | No outcome recorded |
| Phase 2/3 | NCT01151865 Comparator | Feb 2011 → Dec 2013 | delirium | Austin Health | Completed | No outcome recorded |
| Phase 376 trials | ||||||
| Phase 3 | NCT07573969 Comparator | May 2026 → May 2027 expected | — | Ain Shams University | Recruiting | No outcome recorded |
| Phase 3 | NCT07443163 Comparator | Mar → Sep 2026 expected | — | Cairo University | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07326397 Comparator | Feb 2026 → Nov 2027 expected | — | Assiut University | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07330375 Comparator | Jan → Jun 2026 overdue | — | Zagazig University | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07213037 Comparator | Nov 2025 → Nov 2026 expected | — | Assiut University | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07194694 Comparator | Oct 2025 → Jan 2026 | — | Ain Shams University | Completed | No outcome recorded |
| Phase 3 | NCT07080229 Comparator | Jul 2025 → Apr 2026 overdue | cataract, hypertensive disorder | Suez Canal University | Recruiting | No outcome recorded |
| Phase 3 | NCT06979141 Comparator | Jun 2025 → Jun 2026 overdue | — | Al-Azhar University | Recruiting | No outcome recorded |
| Phase 3 | NCT06942000 Comparator | May → Nov 2025 overdue | benign shuddering attacks | Al-Azhar University | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT06865469 Comparator | May 2025 → May 2026 overdue | — | Assiut University | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07013955 Comparator | Apr → Nov 2025 overdue | — | Minia University | Enrolling by invitation | No outcome recorded |
| Phase 3 | NCT06789393 Comparator | Mar 2025 → Mar 2026 overdue | hypospadias | Assiut University | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT06838650 Comparator | Mar 2025 → May 2026 overdue | — | Assiut University | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT06848595 Comparator | Feb 2025 → Jan 2027 expected | — | Tanta University | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07350668 Comparator | Jan 2025 → Jan 2026 | — | Benha University | Completed | No outcome recorded |
| Phase 3 | NCT06624592 Background | Dec 2024 → Nov 2026 expected | delirium | Mayo Clinic | Recruiting | No outcome recorded |
| Phase 3 | NCT06386770 Comparator | Jun 2024 → Feb 2025 | — | Aswan University | Unknown | No outcome recorded |
| Phase 3 | NCT06281977 Comparator | May 2024 → May 2027 expected | ventricular fibrillation, ventricular tachycardia | Ottawa Heart Institute Research Corporation | Recruiting | No outcome recorded |
| Phase 3 | NCT06235606 Comparator | May 2024 → Nov 2025 | — | The University of Hong Kong | Completed | No outcome recorded |
| Phase 3 | NCT06274333 Comparator | Feb 2024 → Aug 2026 overdue | nephrolithiasis | Al-Azhar University | Recruiting | No outcome recorded |
| Phase 3 | NCT06067958 Comparator | Dec 2023 → Dec 2025 overdue | retinopathy of prematurity | Assaf-Harofeh Medical Center | Recruiting | No outcome recorded |
| Phase 3 | NCT05988671 Comparator | Aug 2023 → Aug 2024 | gallbladder disorder | Al-Azhar University | Completed | No outcome recorded |
| Phase 3 | NCT05849779 Comparator | Jul 2023 → May 2026 overdue | acute respiratory distress syndrome | University Hospital, Clermont-Ferrand | Recruiting | No outcome recorded |
| Phase 3 | NCT06386783 Comparator | Jul 2023 → Jul 2024 | — | Aswan University | Unknown | No outcome recorded |
| Phase 3 | NCT06720220 Comparator | Jun 2023 → Aug 2024 | — | Zagazig University | Completed | No outcome recorded |
| Phase 3 | NCT05671081 Comparator | Jan 2023 → Mar 2024 | — | Ain Shams University | Completed | No outcome recorded |
| Phase 3 | NCT05674877 Comparator | Dec 2022 → Jun 2023 | cirrhosis of liver | Cairo University | Completed | No outcome recorded |
| Phase 3 | NCT05624151 Comparator | Nov 2022 → May 2023 | — | Ain Shams University | Completed | No outcome recorded |
| Phase 3 | NCT05340803 Comparator | Nov 2022 → Jan 2025 | traumatic brain injury | Assiut University | Unknown | No outcome recorded |
| Phase 3 | NCT05887258 Background | May 2022 → May 2024 | — | Unai Ortega Mera | Completed | No outcome recorded |
| Phase 3 | NCT05304598 Comparator | Mar 2022 → Aug 2024 | — | Maimonides Medical Center | Withdrawn | No outcome recorded |
| Phase 3 | NCT05335655 Comparator | Jan → Jun 2022 | — | Hospital Central "Dr. Ignacio Morones Prieto" | Unknown | No outcome recorded |
| Phase 3 | NCT05158348 Comparator | Nov 2021 → Apr 2022 | — | Kasr El Aini Hospital | Unknown | No outcome recorded |
| Phase 3 | NCT04356638 Comparator | Oct 2021 → Dec 2023 | anxiety | King Faisal Specialist Hospital & Research Center | Unknown | No outcome recorded |
| Phase 3 | NCT04300985 Comparator | Oct 2021 → Dec 2022 | gallbladder disorder | University of Sao Paulo General Hospital | Completed | No outcome recorded |
| Phase 3 | NCT04082767 Comparator | Jun 2021 → Sep 2024 | — | Douglas Fraser | Unknown | No outcome recorded |
| Phase 3 | NCT04801589 Comparator | May 2021 → Apr 2026 overdue | delirium, post-traumatic stress disorder | Vanderbilt University Medical Center | Recruiting | No outcome recorded |
| Phase 3 | NCT04697537 Comparator | Feb → Apr 2021 | osteoarthritis, knee | Medical University of Graz | Completed | No outcome recorded |
| Phase 3 | NCT04668456 Comparator | Aug 2020 → Mar 2021 | — | Menoufia University | Unknown | No outcome recorded |
| Phase 3 | NCT04355962 Comparator | Apr 2020 → Jun 2021 | COVID-19, acute respiratory distress syndrome | University of Zurich | Completed | No outcome recorded |
| Phase 3 | NCT04096768 Background | Sep 2019 → Sep 2021 | — | Lebanese American University Medical Center | Unknown | No outcome recorded |
| Phase 3 | NCT04358367 Comparator | May → Oct 2019 | — | Egyptian Biomedical Research Network | Completed | No outcome recorded |
| Phase 3 | NCT03883347 Comparator | Mar 2019 → Mar 2022 | — | University of Athens | Unknown | No outcome recorded |
| Phase 3 | NCT03477344 Comparator | Jan 2019 → Jun 2021 | delirium | University Hospital, Brest | Completed | No outcome recorded |
| Phase 3 | NCT04148599 Comparator | Jan 2018 → Jun 2020 | inflammatory disease | Norma Osama Abdalla Zayed | Completed | No outcome recorded |
| Phase 3 | NCT02987985 Background | Oct 2017 → Sep 2019 | obstructive sleep apnea syndrome, respiratory underresponsiveness to hypoxia and hypercapnia | University of Saskatchewan | Completed | No outcome recorded |
| Phase 3 | NCT03171740 Comparator | Jun → Dec 2017 | delirium | Brasilia University Hospital | Completed | No outcome recorded |
| Phase 3 | NCT03063073 Comparator | Feb → May 2017 | female breast carcinoma | South Egypt Cancer Institute | Completed | No outcome recorded |
| Phase 3 | NCT03046238 Comparator | Feb → Apr 2017 | breast cancer | South Egypt Cancer Institute | Unknown | No outcome recorded |
| Phase 3 | NCT02563288 Comparator | Aug 2016 → Aug 2017 | brain aneurysm, brain neoplasm | George Papanicolaou Hospital | Unknown | No outcome recorded |
| Phase 3 | NCT02927379 Comparator | Jun → Dec 2016 | digestive system cancer | Assiut University | Completed | No outcome recorded |
| Phase 3 | NCT03211871 Comparator | May 2016 → Aug 2017 | neuropathy, painful | Bogomolets National Medical University | Unknown | No outcome recorded |
| Phase 3 | NCT03466632 Comparator | Apr 2016 → Apr 2020 | colonic disorder | Tanta University | Unknown | No outcome recorded |
| Phase 3 | NCT02684019 Comparator | Jan → Sep 2016 | — | Theodor Bilharz Research Institute | Completed | No outcome recorded |
| Phase 3 | NCT02658760 Comparator | Jun 2015 → Dec 2016 | — | Hamidreza Mahboobi | Unknown | No outcome recorded |
| Phase 3 | NCT03067896 Comparator | Jun 2015 → Mar 2017 | — | Assiut University | Unknown | No outcome recorded |
| Phase 3 | NCT02384343 Comparator | Apr 2015 → May 2016 | movement disorder | St. Justine's Hospital | Completed | No outcome recorded |
| Phase 3 | NCT02331563 Comparator | Oct 2014 → Sep 2015 | — | Kırıkkale University | Withdrawn | No outcome recorded |
| Phase 3 | NCT03236727 Comparator | Mar 2014 → May 2016 | — | George Papanicolaou Hospital | Completed | No outcome recorded |
| Phase 3 | NCT02327156 Comparator | Jan → Aug 2014 | — | Magrabi Eye & Ear Hospital | Completed | No outcome recorded |
| Phase 3 | NCT01739933 Comparator | May 2013 → Jul 2019 | delirium, infectious disease with sepsis | Vanderbilt University Medical Center | Completed | No outcome recorded |
| Phase 3 | NCT03323593 Comparator | May → Dec 2013 | — | The University of Hong Kong | Completed | No outcome recorded |
| Phase 3 | NCT01805726 Comparator | Feb → Mar 2013 | — | Saint-Joseph University | Completed | No outcome recorded |
| Phase 3 | NCT01837290 Comparator | Dec 2012 → Jan 2014 | chronic renal failure syndrome, osteoporosis | Baskent University | Completed | No outcome recorded |
| Phase 3 | NCT02058485 Comparator | Jan 2012 → Apr 2013 | hypertensive disorder | Duzce University | Completed | No outcome recorded |
| Phase 3 | NCT01528891 Comparator | Jan 2012 → Aug 2014 | — | Peter Davis | Completed | No outcome recorded |
| Phase 3 | NCT01152021 Comparator | Aug 2011 → Jul 2014 | — | Boston Children's Hospital | Terminated | No outcome recorded |
| Phase 3 | NCT00875550 Comparator | Jan 2010 → Jan 2011 | — | Pfizer | Completed | No outcome recorded |
| Phase 3 | NCT01169467 Comparator | Oct 2009 → Nov 2013 | intracranial hypertension | Duke University | Completed | No outcome recorded |
| Phase 3 | NCT01065701 Comparator | Jul 2009 → Aug 2010 | — | The University of Hong Kong | Completed | No outcome recorded |
| Phase 3 | NCT00848991 Comparator | Feb 2009 → Feb 2010 | — | The Cooper Health System | Completed | No outcome recorded |
| Phase 3 | NCT01887184 Comparator | Jan 2009 → Mar 2010 | digestive system disorder | The University of Hong Kong | Completed | No outcome recorded |
| Phase 3 | NCT01353456 Comparator | May 2008 → Mar 2010 | — | The University of Hong Kong | Completed | No outcome recorded |
| Phase 3 | NCT00481312 Comparator | Jun 2007 → Aug 2009 | — | Orion Corporation, Orion Pharma | Completed | No outcome recorded |
| Phase 3 | NCT00971178 Comparator | Feb 2006 → Mar 2008 | — | The University of Hong Kong | Completed | No outcome recorded |
| Phase 3 | NCT01132794 Comparator | — | — | The University of Hong Kong | Completed | No outcome recorded |
| Phase 4215 trials | ||||||
| Phase 4 | NCT07377981 Comparator | Aug 2026 → Jan 2029 expected | — | The First Affiliated Hospital with Nanjing Medical University | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07651956 Comparator | Jun 2026 → May 2028 expected | anxiety | Icahn School of Medicine at Mount Sinai | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07369128 Comparator | Jun 2026 → Dec 2027 expected | subacute delirium | Boston Children's Hospital | Recruiting | No outcome recorded |
| Phase 4 | NCT07611890 Comparator | May → Aug 2026 overdue | — | Rawalpindi Institute of Cardiology | Recruiting | No outcome recorded |
| Phase 4 | NCT07179913 Comparator | May → Nov 2026 expected | depressive disorder | The First Hospital of Jilin University | Active not recruiting | No outcome recorded |
| Show all 215 trials opens the full record — a long page | ||||||
| Phase not applicable275 trials | ||||||
| — | NCT07486336 Comparator | Sep 2026 → Sep 2028 expected | cognitive disorder | Ente Ospedaliero Ospedali Galliera | Not yet recruiting | No outcome recorded |
| — | NCT07398066 Comparator | Jul 2026 → Jul 2027 expected | brain cancer, meningioma | University of Malaya | Not yet recruiting | No outcome recorded |
| — | NCT07640516 Comparator | Jul 2026 → Jan 2027 expected | — | Kasr El Aini Hospital | Recruiting | No outcome recorded |
| — | NCT07665463 Background | Jul → Dec 2026 expected | — | Jagiellonian University | Not yet recruiting | No outcome recorded |
| — | NCT07683416 Comparator | Jul 2026 → Jan 2027 expected | — | Zagazig University | Not yet recruiting | No outcome recorded |
| Show all 275 trials opens the full record — a long page | ||||||
Evidence & citations 51 cited values
Every value below carries the sentence it was read from. 1,837 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | dexmedetomidine | “Dexmedetomidine-esketamine combination (1 μg/mL dexmedetomidine and 0.5 mg/mL esketamine) will be administered after anesthesia induction, firstly as a loading dose at a rate...” NCT07576517 ↗1774“Dexmedetomidine is a potent selective α 2 adrenoceptor agonist that was reported in many previous studies as an adjunct to regional and general anesthesia, with significant...” NCT05385523 ↗ “The aim of this study will be to investigate the population pharmacokinetics and pharmacodynamics of rectal dexmedetomidine Niosomes for Postoperative Analgesia in Pediatric...” NCT05340725 ↗ “Dexmedetomidine, a novel α2-agonist with an eight-fold affinity for α2-adrenergic receptors (sedate and analgesic effects) as clonidine, while exerts much less α1-effects., has...” NCT05727098 ↗ “patients who will receive intravenous (I.V.) ketamine in a dose of 0.25 mg/kg diluted in 5 ml normal saline plus dexmetedomidine 0.25ug/kg followed by infusion of...” NCT07513935 ↗ “General anesthesia without intraoperative opioids using dexmedetomidine, ketamine, lidocaine, sevoflurane, non-opioid co-analgesics, procedure-specific regional analgesia, and...” NCT07665463 ↗ “Patient will be given a peripheral nerve block from their treating anesthesiologist before the operation (in the OR) with an conventional ultrasound guided femoral and sciatic...” NCT04697537 ↗ “The investigators will not mandate the sedative type, but rather encourage the use of sedatives that are already routinely used in participating ICUs (typically a...” NCT05849779 ↗ “Dexmedetomidine,an α2 adrenergic agonist,has hypnotic,analgesic, anxiolytic,antisympathetic effects,which could facilitate the sedation of patients while maintaining their...” NCT02613806 ↗ “Dexmedetomidine is a highly selective alpha-2 adrenergic receptor agonist that reduces the release of norepinephrine by inhibiting activity in the locus coeruleus, a key brain...” NCT07167316 ↗ “Intravenous Induction of Anesthesia Using a Mixture of Ketamine and dexmedetomidine in a ratio of 1 mg ketamine to 0.5 ug dexmedetomidine given in a dose of 1mg/kg ketamine and...” NCT07002073 ↗ “Dexmedetomidine (DEX) an α-2 adrenergic receptor agonist, because its sympatholytic and antinociceptive properties may ensure optimal intraoperative hemodynamic stability...” NCT03132259 ↗ “Then , they will receive ketamine 0.1 mg/kg /hr and dexmedetomidine0.2ug/kg/hr in their maintenance syringes prepared in 20 ml normal saline in a concentration of 1mg/ml...” NCT05402189 ↗ “Dexmedetomidine (Precedex) is a highly selective alpha 2 adrenoreceptor agonist which produce sedation, anxiolysis, analgesia, and decreasing inflammatory response to...” NCT06514040 ↗ “Group D: : will receive dexmedetomidine (1 μg/kg) diluted in 5ml normal saline sprayed via long nostril syringe into oropharynx , the vocal cords and tracheobronchial tree 5...” NCT06374017 ↗ “Minimal infusion rates of dexmedetomidine (0.1-0.4 μg/kg/h) in the D group and fentanyl (0.01-0.05 μg/kg/min) in the PF group were continued during colonoscopy, which lasted...” NCT06148103 ↗ “The use of dexmedetomidine in these patient populations may explain the high rate of hypotension reported in a recent study in trauma patients where almost 50% of patients had...” NCT03285087 ↗ “Trans-foraminal Lumbar Epidural Injection of Dexmedetomidine Against Magnesium Sulfate When Combined With Dexamethasone in Uni-lateral Lower Limb Radicular Pain. Multi-centeric...” NCT05271721 ↗ “dexmedetomidine ( administered intravenously, Load: 0.25 mcg/kg IV over 10 minutes , Maintenance 0.2-0.7 mcg/kg/hr continuous IV infusion according to haemodynamics and...” NCT06653244 ↗ “Standard of Care analgosedation of choice using propofol, fentanyl, dexmedetomidine, morphine, hydromorphone, midazolam, or lorazepam administered according to the...” NCT06429657 ↗ “A pre-prepared 50 ml syringe is utilized, containing 400 mcg of dexmedetomidine (4 ml), 50 mg of S-ketamine (2 ml), 400 mg of 2% lidocaine (20 ml), and 0.9% NaCl to a total...” NCT07084753 ↗ “After endotracheal intubation, anesthesia was maintained with 1.5-3% sevoflurane, 0.3-0.5 μg/kg/h dexmedetomidine and 2-4 μg/mL target-controlled infusion of remifentanil in...” NCT04680650 ↗ “Patients in the TIVA group had anesthesia induced with propofol 2 mg/kg , fentanyl 1 ug/kg and maintained with propofol. 200 ug/kg/min, fentanyl 0.1ug/kg/min, dexmedetomidine 1...” NCT06423846 ↗ “Dexmedetomidine has been shown to improve myocardial perfusion, reduce arrhythmia incidence, reduce inflammatory response, and reduce mortality in patients with coronary artery disease.” NCT03601091 ↗ “the study aim to compare the analgesic effect of intravenous dexmedetomidine and fascia iliaca block preoperatively to assist positioning patients for performance of spinal anesthesia.” NCT05705726 ↗ “The primary objective of this study is to evaluate the analgesic efficacy of Dexmedetomidine Transdermal System (DMTS), compared with placebo, in participants following abdominoplasty.” NCT04242407 ↗ “Recent studies have shown very promising results in terms of efficacy and duration of block by mixing bupivacaine with dexmedetomidine, alongwith minimal side effects to the patients.” NCT05244252 ↗ “Group A: Caudal Dexmedetomidine block group (DEXM) (n= 16) will receive caudal block using the bupivacaine 0.25% and Dexmedetomidine 1 μg/kg with the conventional general anesthesia,” NCT03101137 ↗ “All subjects in this arm receive Dexmedetomidine with a prepared concentration of 10 μg/mL. A loading dose of 1.0 μg/kg is administered by infusion and completed within 10 minutes.” NCT07644663 ↗ “IV 0.2 mic/ kg of dexmedetomidine will be diluted over 10 ml saline and given to the patient over 10 minutes before induction and assess the feasibility of classic LMA insertion” NCT07562308 ↗ “Dexmedetomidine is a selective, specific, lipophilic and potent α2 adrenergic receptor agonist with sedative, anxiolytic, analgesic, antihypertensive and sympatholytic effects.” NCT03479216 ↗ “This study will be conducted to investigate the efficacy of adding dexmedetomidine in STB for postoperative analgesia in patients undergoing arthroscopic shoulder surgery.” NCT07046325 ↗ “Dexmedetomidine is new highly selective α2 adrenoceptor agonist and has been approved by Food and Drug Administration as intravenous (IV) sedative and co-analgesic drug.” NCT06970574 ↗ “Compare the opioid based anesthesia with Fentanyl and Remifentanyl to opioid free anesthesia with dexmedetomidine and lidocaine and their effect on postoperative pain.” NCT03417193 ↗ “Patients will receive a scalp block with a 20 ml syringe containing 1 mg/kg of 0.5% bupivacaine and 1 µg/kg of dexmedetomidine, with the remainder filled with saline.” NCT07698665 ↗ “Patients received general anesthesia and bilateral ultrasound guided transmuscular quadratus lumborum block with (20ml Bupivacaine 0.25%) + (Dexmedetomidine Imic/kg)” NCT06825286 ↗ “Total IntraVenous Anesthesia - to achieve deep-sedation via chemical analgesic (propofol, dexmedetomidine, fentanyl, hydromorphone); continuous intravenous infusion.” NCT07672301 ↗ “Dexmedetomidine, a highly selective alpha2-adrenoceptor agonist used for short-term sedation of mechanically ventilated patients, has minimal effect on ventilation.” PMID 15505441 ↗ Nov 2004 “GROUP A will receive Dexmedetomidine in dose of of 0.5μg/ kg/hour It elicits a biphasic blood pressure response: a short hypertensive phase followed by hypotension.” NCT04917029 ↗ “Dexmedetomidine is a highly selective, alpha2-adrenergic receptor agonist that has been widely used for adult anesthesia and as a sedative in intensive care units.” NCT05786833 ↗ “Dexmedetomidine (Dexamed) is a selective α2-adrenoceptor agonist with sedative and neuroprotective properties, known to reduce ICP without respiratory depression .” NCT07199595 ↗ “may use a combination of fentanyl, midazolam, dexmedetomidine infusion (with or without loading dose), and/or low-dose propofol by intermittent bolus or infusion” NCT03263117 ↗ “Patients will be nebulized with mixture of 2% lidocaine 10 ml and dexmedetomidine 1 μg/kg by using wall nebulizer for 15 min before awake fiberoptic intubation.” NCT06088875 ↗ “ketamine (1mg/kg) prepared for concentration 10mg/ml, Dexmedetomidine (0.5microg/kg slow IV) prepared for concentration of 5mic /ml in 2 separate syringes.” NCT05948267 ↗ “Dexmedetomidine ,an alfa-2 adrenoreceptor agonist, is being used and adjuvant capable of prolonging duration of sensory and motor block on nerve blocks.” NCT02544893 ↗ “Patients received a loading dose of dexmedetomidine at 1 µg/kg over 10 minutes, followed by a continuous infusion at 1 µg/kg/h throughout the procedure.” NCT05581485 ↗ “Group B: Patients who will receive transversus abdominis plane block with - 18ml Bupivacaine 0.25%+ 2ml Dexmedetomidine (1µg/Kg diluted in 2ml saline).” NCT07590752 ↗ “Dexmedetomidine, a selective α2-adrenoreceptor agonist, was shown to be a potent antinociceptive agent when given intrathecally in animals and humans.” PMID 23727917 ↗ 2013 “Dexmedetomidine or Hyalase : Which of Them Can Augment Lumbar Epidural Steroid Injection in Failed Back Surgery Patients. A Randomized Clinical Trial” NCT05370963 ↗ “Dexmedetomidine is a drug used for sedation in critically ill patients that provides some pain relief and controls the bodies response to stress.” NCT01934049 ↗ “The investigators will use vasopressin as the primary vasopressor and a heart rate-calibrated dexmedetomidine infusion in septic shock patients.” NCT06302998 ↗ “Patients were randomly allocated to receive either intravenous dexmedetomidine (1 μg/kg) or dexamethasone (8 mg) after induction of anesthesia.” NCT07426081 ↗ “Use of deeper plane of inhaled anesthetics or adjuncts (opioids, propofol, dexmedetomidine or ketamine for maintenance of general anesthesia.” NCT03962725 ↗ “Studies showed dexmedetomidine (DEX) could improve surgical field, but the effect for functional nasal endoscopic surgery (FESS) was unclear.” NCT04276545 ↗ “Sedation was induced with a dexmedetomidine 0.5μg/kg over 10 min loading, followed by a maintenance infusion of 0.2-0.7 μg/kg/h for one hour.” NCT01447875 ↗ “Two syringes containing ketodex-ketamine (1 mg/kg) and dexmedetomidine (1 µg/kg)-each diluted with 0.9% saline and infused over 10 minutes.” NCT07246447 ↗ “Dexmedetomidine is a potent and highly selective alpha-2 receptor agonist with sympatholytic, sedative, amnestic, and analgesic properties.” NCT06592027 ↗ “All patients were administered a bolus of ketamine (0.5 mg/kg) and were started continuous infusion dexmedetomidine at a dose 0.7 μg/kg/h.” NCT05514652 ↗ “Dexmedetomidine (trade name Precedex) is approved by U.S. Food and Drug Administration (FDA) and indicated for sedation (calming effect).” NCT01969903 ↗ “Peroperative opioid free anesthesia will be obtained via a combination of dexmedetomidine, ketamine, lidocaine and magnesium sulfate” NCT03124680 ↗ “In the Total i.v. anaesthesia (TIVA) group (n=60), patients underwent opioid-free TIVA with propofol, ketamine, and dexmedetomidine.” PMID 24554545 ↗ Feb 2014 “BioXcel Therapeutics has developed BXCL501 (dexmedetomidine: sublingual film) to reduce symptoms associated with opioid withdrawal.” NCT05712707 ↗ “Intravenous sedation in control group will be continued as initiated at the ICU e.g. propofol, fentanyl, midazolam, dexmedetomidine” NCT04355962 ↗ “One prospect is dexmedetomidine (Precedex®), which is FDA-approved for short-term (≤24 hours) sedation in the intensive care unit.” NCT01007773 ↗ “Dex group: Dexmedetomidine 2mcg/ml-containing 1% lidocaine scalp injection by neurosurgeon(dosage: according to incision length)” NCT01606969 ↗ “The DEX Group, consisting of 29 patients, received 2.5 ml of hyperbaric bupivacaine mixed with dexmedetomidine (10 μg; 0.5 ml).” NCT06216197 ↗ “dexmedetomidine was infused under ECG monitoring at an initial rate of 0.5 μ G/kg (more than 10min), then changed to 0.2ug/kg/h” NCT05577962 ↗ “Patients in this group will receive errector spine plane block with 30 ml bupivacaine 0.25% plus 1ml of 1µg/kg Dexmedetomidine” NCT04650737 ↗ “Dexmedetomidine (DEXM) is a highly selective α2-adrenoceptor agonist that has been used increasingly in pediatric anesthesia.” NCT03791879 ↗ “Dexmedetomidine is a highly selective alpha 2 adrenergic receptor agonist with sedative, analgesic, and anxiolytic effects.” NCT07576543 ↗ “Analgesia will be offered by syringe containing ketamine and Dexmedetomidine in induction and maintenance according to IBW.” NCT06650371 ↗ “Dexmedetomidine is a highly selective α2-adrenergic receptor agonist with sedative, anxiolytic, and analgesic properties.” NCT07166614 ↗ “If systolic BP is still ≥ 140 mmHg, then dexmedetomidine will be applied using an infusion pump at a dose of 0.2 μg/kg/h.” NCT03207100 ↗ “bupivacaine 0.25% and dexmedetomidine 0.5 mcg/mL (total volume of 10 mL) by epidural-catheter bolus given preoperatively” NCT05069311 ↗ “Group II received 20 ml of 0.25% bupivacaine with supplementation of 1 mL containing 100µg dexmedetomidine bilaterally” NCT03746418 ↗ “continuous intravenous infusion of ketamine (5 μg/kg/min) and dexmedetomidine (0.6 μg/kg/h) during general anesthesia.” NCT07588802 ↗ “Parasternal block with Bupivacaine 0.25% + Epinephrine 1:200,000 x 60cc + Dexamethasone 5mg and Dexmedetomidine 50mcg” NCT05191745 ↗ “In the D1 group, patients were administered 20 mL of 0.25% isobaric bupivacaine with 0.5 mcg/kg of dexmedetomidine.” NCT06703229 ↗ “Dexmedetomidine Transdermal Systems (DMTS) Treatment for Agitation Associated With Dementia of the Alzheimer's Type” NCT06052254 ↗ “Group (D): (n=30) will receive Dexmedetomidine infusion 0.1- 0.2 μg/kg/hour titrated to desired level of sedation.” NCT05474183 ↗ “the use of dexmedetomidine as a pharmacological treatment for delirium in critical illness patients with covid-19” NCT05963958 ↗ “Group D (n=80) will receive dexmedetomidine 0.5 µg/kg i.v. (Precedex®, Hospira Inc, USA, Vials of 200 mg/2 ml)” NCT06627816 ↗ “Dexmedetomidine, a highly selective α2-adrenergic receptor agonist, offers several advantages as an adjuvant.” NCT06769737 ↗ “Anesthesia is maintained with continuous infusion of propofol 1.5-2mg/kg/h and dexmedetomidine 0.2-1ug/kg/h.” NCT02739958 ↗ “will receive bupivacaine 0.25% (3ml) + dexmedetomidine (1 mic/kg), total volume 5ml by adding normal saline” NCT07380139 ↗ “A mixture of 0.5 ml /kg bupivacaine (0.25%), and 0.5µg/Kg dexmedetomidine and Epinephrine 5 microgram/ ml.” NCT03408184 ↗ “Evaluation of the Dexmedetomidine Transdermal Systems for Postoperative Analgesia Following Abdominoplasty” NCT05412992 ↗ “Patients will receive adjuvant dexmedetomidine (25mcg) and dexamethasone (5mg) in addition to bupivacaine.” NCT06658054 ↗ “one under complete intravenous anesthesia (infusion of Propofol, Ketamine, Lignocaine and Dexmedetomidine)” NCT06390046 ↗ “An opioid-free general anesthetic technique utilizing dexmedetomidine, ketamine, and lidocaine infusions” NCT02752477 ↗ “Dexmedetomidine (DEX) is a selectiveα2 adrenergic receptor agonist with sedative and analgesic effects.” NCT07125573 ↗ “Total intravenous anesthesia with propofol and dexmedetomidine hydrochloride and ketamine hydrochloride” NCT04144153 ↗ “Caudal block will be performed with 0.75ml/kg of 0.25% bupivacaine containing 1 mic/kg dexmedetomidine.” NCT05233683 ↗ “Intraoperative continuous intravenous infusion of 2-6 mg/kg/h propofol, 0.5-1.0 μg/kg/h dexmedetomidine” NCT07603596 ↗ “Continuous infustion of dexmedetomidine at 0.2 ~ 1.0 mcg/kg/hr with sevoflurane concentration of 1 MAC” NCT01634594 ↗ “Effect of Dexmedetomidine on Gastric Emptying, Assessed by Ultrasound in Laparoscopic Cholecystectomy” NCT06634524 ↗ “Dexmedetomidine (Pfizer, Kirkland, Quebec), single-dose, 4 mcg/kg (0.04 mL/kg) of 100 mcg/mL solution” NCT04195256 ↗ “Effect of intra-articular dexmedetomidine on postoperative analgesia after arthroscopic knee surgery.” PMID 18567675 ↗ Jun 2008 “Anesthesia will be maintained with dexmedetomidine infusion at 0.2-1.4 µg/kg/h and 1 MAC sevoflurane.” NCT07105839 ↗ “Participants will receive a dexmedetomidine infusion in addition to low dose sevoflurane anesthesia.” NCT05369949 ↗ “Subjects will receive standard of care anesthesia Sevoflurane, with intravenous push Dexmedetomidine” NCT06624592 ↗ “Subjects will be given a rectus sheath block containing dexmedetomidine, ropivacaine, and ketorolac” NCT03817034 ↗ “1µg/kg of dexmedetomidine is given 30 minutes prior to intravenous cannulation or lumbar puncture” NCT03564093 ↗ “It is composed by Dexmedetomidine (Dexdor), Lidocaine, Magnesium Sulfate and ketamine (Ketolar).” NCT05887258 ↗ “Dexmedetomidine is an alpha-2 adrenoceptor agonist with analgesic and neuroprotec-tive effects.” NCT07074262 ↗ “•Group D (Dexmedetomidine Group): 0.5 µg/kg dexmedetomidine diluted in 100 mL of normal saline.” NCT07377903 ↗ “Dexmedetomidine Transdermal System (DMTS) for Post-Operative Analgesia Following Bunionectomy” NCT02953054 ↗ “Infusing Dexmedetomidine which load dose 0.5μg/kg in 10min then changed into 0.5-1.0μg/kg•h” NCT02727712 ↗ “TIVA opioid-free anesthesia: dexmedetomidine 1-1.5 mcg/kg (corrected weight) for 40 minutes” NCT04854252 ↗ “In group A,patients will be given 0.25% bupivacaine 1 mL/kg with dexmedetomidine0.5 μg/kg.” NCT06735443 ↗ “a conscious sedation group (dexmedetomidine) and a general anesthesia group (desflurane).” NCT05550714 ↗ “Dexmedetomidine and lidocaine are administered during anesthesia, and opioid is not used.” NCT05076903 ↗ “Group A : will receive bupivacaine 0.25% + dexmedetomidine 1 mic/kg, total volume (20 ml)” NCT06294665 ↗ “plus dexmedetomidineIV bolus 1 μg/kg/10min + infusion pump 0.5 μg /kg/hrs intraoperative” NCT05474040 ↗ “Dexmedetomidine (DEX), is a selective centrally acting α 2-adrenergic receptors agonist” NCT04709315 ↗ “Sedation based on dexmedetomidine and low dosage of ketamine, avoiding GABAergic-drugs” NCT07486336 ↗ “Dexmedetomidine will be injected (1 mcg/kg for 10 minutes and afterward 0.3 mcg/kg/hr)” NCT01991223 ↗ “Patients will receive Ketodex (ketamine- dexmedetomidine mixture in a ratio of 1:1).” NCT07627906 ↗ “dexmedetomidine 1 mic/kg IV over 10 minutes then 0.4 mic/kg/h continuous IV infusion” NCT05619965 ↗ “During surgery, 0.5mcg/kg of dexmedetomidine and 0.1mg/kg ondansetron will be given.” NCT03467750 ↗ “Dexmedetomidine may be an alternative to current drug therapies for breathlessness.” NCT02773797 ↗ “Dexmedetomidine may be an alternative to current drug therapies for breathlessness.” NCT02211118 ↗ “Anesthesia maintenance: Desflurane set at \~1 MAC, Dexmedetomidine 0.2-1.2mcg/kg/h” NCT04894864 ↗ “use of dexmedetomidine as an adjuvant to the patient-controlled propofol sedation” NCT01070680 ↗ “Anesthesia induction: Dexmedetomidine 1µg/kg (intravenous infusion within 10min)” NCT04507165 ↗ “Infusion of dexmedetomidine(1μg/kg) at 10 minutes before anesthesia induction.” NCT02289391 ↗ “Dexmedetomidine Hydrochloride is a high selected a-2 adrenoreceptor agonists.” NCT02691598 ↗ “Intravenous sedation using propofol or dexmedetomidine will be administered.” NCT03404180 ↗ “Infusion of dexmedetomidine at 0.4 μg•kg-1•h-1during anesthesia maintenance.” NCT02143362 ↗ “Dexmedetomidine is a potent and highly selective α2-adrenoreceptor agonist.” NCT05897307 ↗ “lidocaine and dexmedetomidine infusion in 50 ml syringe till end of surgery” NCT05850468 ↗ “Dexmedetomidine (DXM) is a recently released and approved alpha 2 agonist” NCT02102139 ↗ “patients will receive dexmedetomidine 0.2-0.7 mcg/kg/h infusion for 24h.” NCT03285165 ↗ “0.4 mcg/kg dexmedetomidine, max total dose 50mcg in 50 ml N/S infusion” NCT05752799 ↗ “0.3 mcg Kg-1 (actual weight) of dexmedetomidine IV in 20 mL of saline” NCT06289335 ↗ “1 mcg/kg Dexmedetomidine, max total dose 100mcg in 50 ml N/S infusion” NCT07568938 ↗ “Injectable 1 ml/kg of 0.25% ropivacaine with 1mcg/kg dexmedetomidine” NCT05708989 ↗ “Dexmedetomidine is a selective alpha two adreno-receptor agonist.” NCT05291364 ↗ “Dexmedetomidine is a potent alpha-2 adrenergic receptor agonist.” NCT05119101 ↗ “dexmedetomidine bolus dose of 1 mcg/kg followed by 0.3 mcg/kg/h” NCT05962671 ↗ “50 mcg Dexmedetomidine (0.5 cc of standard 100 mcg/ml solution)” NCT06343753 ↗ “Dexmedetomidine 0.5 ug/kg + Propofol + Sevoflurane+ Vecuronium” NCT01584570 ↗ “Sublingual film containing 180 µg of Igalmi (dexmedetomidine)” NCT06041646 ↗ “(1 mL/kg of bupivacaine 0.25% plus 1 μ/kg dexmedetomidine).” NCT03482947 ↗ “Dexmedetomidine 1mcg/kg IV bolus over 10 minutes using IBW” NCT04081545 ↗ “Midazolam, Dexmedetomidine, Lidocaine, Propofol, Ketamine” NCT05172739 ↗ “Dexmedetomidine (DEX) is an alpha-2 adrenoceptor agonist” NCT06793150 ↗ “1. IV dexmedetomidine 2. IV ketamine Both for sedation” NCT03954379 ↗ “loading dose of dexmedetomidine, intravenous midazolam” NCT06493396 ↗ “adding dexmedetomidine 5 μg in the saline component” NCT05525819 ↗ “Dexmedetomidine loading dose 1 μg/kg i.v. infusion.” NCT04941040 ↗ “dexmedetomidine for sedation and sympatholysis” NCT07310524 ↗ “will receive nebulized Dexmedetomidine 3 µg/kg” NCT05872087 ↗ “group (F) receive dexmedetomidine and ketamine” NCT07360327 ↗ “Precedex, dexmedetomidine hydrochloride” NCT04082767 ↗ “Dexmedetomidine as a sedation drug” NCT04142502 ↗ “Administration of Dexmedetomidine” NCT01337739 ↗ “Dexmedetomidine Intranasal Spray” NCT03348423 ↗ “dexmedetomidine (12-20 mcg IV)” NCT07211399 ↗ “Dexmedetomidine 1mcg/kg IV” NCT04197570 ↗ “dexmedetomidine” NCT03596424 ↗ “Dexmedetomidine” NCT06176222 ↗ “Dexmedetomidine” NCT06410404 ↗ “dexmedetomidine” NCT05658692 ↗ |
| Known as | (+)-4-(S)-\[1-(2,3-dimethylphenyl ) ethyl\]-1H-imidazole hydrochloride | “Background Information: Dexmedetomidine is an α-adrenoceptor agonist, and its chemical name is (+)-4-(S)-\[1-(2,3-dimethylphenyl ) ethyl\]-1H-imidazole hydrochloride.” NCT02007798 ↗ |
| Known as | Ai Beining | “Dexmedetomidine was developed by the Orion Pharma (Finland) Corporation and Abott (USA), and introduced to China in 2009 (trade name: Ai Beining).” NCT02007798 ↗ |
| Known as | BXCL501 | “Subjects will be given a sublingual formulation of BXCL501 (dexmedetomidine)” NCT03708315 ↗13“Dexmedetomidine (DEX) for sublingual (SL) administration (BXCL501) - 40µg” NCT06335407 ↗ “Sublingual film containing dexmedetomidine (BXCL501)” NCT04268303 ↗ “Sublingual film containing Dexmedetomidine (BXCL501)” NCT04276883 ↗ “Sublingual film containing dexmedetomidine (BXCL501)” NCT05974527 ↗ |
| Known as | DA-9501 | “The purpose of this study is to examine the efficacy and safety of DA-9501 (Dexmedetomidine) in patients who require sedation during the surgery that requires epidural or...” NCT01438957 ↗ |
| Known as | deksmedetomidine | “One commonly used sedative drug is deksmedetomidine, an α2 receptor agonist.” NCT03601091 ↗ |
| Known as | DEM | “perineural dexamethasone (DEX) versus dexmedetomidine (DEM) when used as adjuvants to ropivacaine in pediatric popliteal sciatic nerve blocks” PMID 41043950 ↗ Oct 2025 |
| Known as | DEX | “After surgery, patient-controlled intravenous analgesia will be established with dexmedetomidine (DEX 1.5 ug/ml), esketamine (ESK 0.5 mg/ml), and sufentanil (1.25 ug/ml),...” NCT07523321 ↗102“Dexmedetomidine (Dex) is a new type of highly selective α2-adrenergic receptor agonist, which has the effects of sedative-hypnotic, anti-inflammatory, stress reduction,...” NCT06207331 ↗ “BACKGROUND: Desaturation is a common complication of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). Dexmedetomidine (DEX), a commonly used...” PMID 33122573 ↗ May 2021 “Dexmedetomidine (DEX) is a centrally acting alpha-2-adrenoceptor agonist that has potential in the management of alcohol withdrawal syndrome (AWS) owing to its ability to...” PMID 26525052 ↗ Nov 2015 “The goal is to determine if the propofol (PR) (sedative agent), dexmedetomidine (DEX)(selective α2-adrenergic receptor (α2-AR) agonist) or their combination could improve and...” NCT05450497 ↗ “Dexmedetomidine (Dex) is an α2-adrenergic agonist sedative commonly used in invasive mechanical ventilation (IMV) that promotes patient wakefulness, has no effect on...” NCT06259565 ↗ “Following Anesthesia induction, dexmedetomidine (DEX) Low Dose group received a DEX loading dose (0.5 µg/kg over 10 min), followed by continuous infusions of 0.3 µg/kg/h,...” NCT07145814 ↗ “A randomized double-blind controlled trial was conducted to investigate whether the administration of DEX, immediately after delivery and for patient-controlled intravenous...” PMID 32210537 ↗ Mar 2020 “Dexmedetomidine (DEX), a sedative commonly used in EVT, can stabilize hemodynamics by inhibiting the sympathetic nervous system and alleviate ischemia-reperfusion injury...” PMID 38439027 ↗ Mar 2024 “This study aims to evaluate the effect of intranasal dexmedetomidine (Dex) administered before combined spinal-epidural labor analgesia on the incidence of postpartum...” NCT07501728 ↗ “Research focuses on the role of intravenous (IV) nefopam, dexmedetomidine (DEX), and meperidine in averting shivering episodes in adult individuals receiving SA for surgical...” PMID 41346412 ↗ Dec 2025 “BACKGROUND: To determine whether continuous intravenous infusion of dexmedetomidine (DEX) can affect the incidence of Emergence Agitation (EA) after general anesthesia in...” PMID 26464000 ↗ Oct 2015 “Dexmedetomidine (DEX) a potent α 2 agonist that have unique analgesic, anxiolytic and sedative profile has been called upon as attractive adjunct in general as well as regional...” NCT04304157 ↗ “We hypothesized that the intraoperative administration of dexmedetomidine (DEX), a sympatholytic agent, would reduce the stress response and improve the quality of recovery in...” PMID 22824921 ↗ Jan 2013 “PURPOSE: To compare dexmedetomidine (DEX) with standard care (SC, either propofol or midazolam) for long-term sedation in terms of maintaining target sedation and length of...” PMID 18795253 ↗ Sep 2008 “This meta-analysis aimed to systematically collect the current evidence regarding the efficacy and safety of dexmedetomidine (DEX) as an anesthetic adjuvant for patients...” PMID 24974190 ↗ Jun 2014 “Dexmedetomidine (DEX), a highly selective α2-adrenoreceptor agonist, is a centrally acting non-opioid agent increasingly utilized in clinical practice for its antinociceptive...” NCT07389096 ↗ “who were randomised to receive either dexmedetomidine sedation (DEX) with caudal block or general sevoflurane anaesthesia with tracheal intubation and caudal block (GA) for...” PMID 30916007 ↗ Mar 2019 “Dexmedetomidine (DEX) is increasingly being used as a sedative for monitored anesthesia care (MAC) because of its analgesic properties, "cooperative sedation," and lack of...” PMID 19713256 ↗ Aug 2009 “STUDY OBJECTIVES: To assess the effect of dexmedetomidine (DEX) on postoperative sleep quality using polysomnography (PSG) to identify possible interventions for postoperative...” PMID 36944937 ↗ Mar 2023 “The aim of this study was to evaluate the efficacy of remifentanil (REM) versus dexmedetomidine (DEX) for treatment of cardiac surgery (CS) patients with moderate to severe NIV...” PMID 33209418 ↗ Oct 2020 “Dexmedetomidine (Dex) is a highly selective centrally acting α2-adrenoreceptor agonist that produces cooperative sedation, anxiolysis, and analgesia with minimal respiratory depression.” NCT04327726 ↗ “Dexmedetomidine (DEX) is a highly selective alpha2 adrenoceptor agonist with broad pharmacological effects, including sedation, analgesia, anxiolysis, and sympathetic tone inhibition.” PMID 31668347 ↗ Oct 2019 “This prospective, randomized, double-blind, placebo-controlled study evaluated the effect of dexmedetomidine (DEX) for reducing the incidence and severity of propofol injection pain.” PMID 25342205 ↗ Oct 2014 “Dexmedetomidine (DEX), a highly selective alpha-2 receptor agonist, is increasingly used in anesthesia with sedative, hypnotic, anxiolytic, sympatholytic, and analgesic effects.” NCT05863416 ↗ “The aim of the study was to evaluate safety and efficacy of melatonin (Mel) and dexmedetomidine (Dex; intranasal and sublingual application) for sleep induction prior to EEG.” PMID 38725985 ↗ Apr 2024 “Dexmedetomidine (D) group, where Dex. (Precedex, hospira, Egypt) 0.8 μg/kg was given intravenously over 10 min as a loading dose, and then infused at a rate of 0.4 μg/kg/h;” NCT05271253 ↗ “The medication in question (dexmedetomidine, DEX) has been proven to be a safe and reliable sedative in different settings even though its use is off-label in pediatrics.” NCT03399838 ↗ “After surgery, patient-controlled intravenous analgesia will be established with dexmedetomidine (DEX 1.5 ug/ml), esketamine (ESK 0.5 mg/ml), and sufentanil (1.25 ug/ml)” NCT07525999 ↗ “The purpose of this study was to compare the perioperative effects of the intramuscular (i.m.) alpha 2 agonist, dexmedetomidine (DEX), and midazolam (MID) premedication.” PMID 7943770 ↗ Oct 1994 “Dexmedetomidine (DEX) α-2 adrenergic receptor consists of three α-2 isoreceptors (α-2a, α-2b and α-2c), which regulate the various pharmacodynamic effects of this drug .” NCT04838379 ↗ “We evaluated bilateral ultrasound (US)-guided single shot erector spinae plane (ESP) block at the level of lumbar 3 (L3) vertebra with or without dexmedetomidine (Dex).” NCT03746418 ↗ “Recently we have introduced Intra-nasal Dexmedetomidine (IN DEX), with an initial impression of much improved drug acceptance and possibly improved efficacy over TFS.” NCT04270708 ↗ “Postoperative delirium can significantly reduce the short-term and long-term quality of life in elderly patients, which can be alleviated by dexmedetomidine (DEX).” PMID 37433729 ↗ Jul 2023 “This study evaluated dexmedetomidine (DEX) on NGF, BDNF, GDNF, and EPI in severe alcohol withdrawal and related their plasma concentrations to DEX concentrations.” PMID 25638740 ↗ Jan 2015 “Dexmedetomidine (Dex) activates the α2 adrenergic receptor that is present within the locus coeruleus, leading to anxiolysis, hypnosis, analgesia, and sedation.” NCT06186895 ↗ “Patients were randomized to receive sufentanil 0.05ug/kh/h + dexmedetomidine 0.1ug/kg/h (DEX group) or sufentanil 0.05ug/kg/h + saline (control group) for 48h.” NCT03117023 ↗ “OBJECTIVE: We attempted to manage the systematic review and a meta-analysis to clarify the efficacy of dexmedetomidine (DEX) in potential prevention on CRBD.” PMID 34967355 ↗ Dec 2021 “Dexmedetomidine (Dex), a highly selective α2-adrenergic receptor agonist, is widely used for sedation and analgesia in the ICU or as an anesthetic adjuvant.” NCT05577871 ↗ “Dexmedetomidine (DEX) has sympatholytic, sedative, analgesic, and anxiolytic effects that attenuate the catecholamine response to perioperative stress.” NCT00398827 ↗ “Dexmedetomidine (DEX), a highly potent and selective α2-adrenoceptors (α2R) agonist used in clinical practice for sedation, analgesia, and anxiolysis” NCT04289142 ↗ “Dexmedetomidine (DEX), a selective agonist of α2-adrenergic receptors, can be an effective adjuvant to local anesthetics for peripheral nerve block.” NCT02766556 ↗ “Administration of dexmedetomidine (DEX) in the pediatric population for its sedative, analgesic, and anxiolytic properties has been widely reported” PMID 26332857 ↗ Nov 2015 “Dexmedetomidine (DEX). DEX, (S)-4-\[1-(2,3 dimethylphenyl)ethyl\]-3H-imidazole\], is a selective and potent α2-adrenergic receptor (α2-AR) agonist” NCT04661475 ↗ “Dexmedetomidine(DEX) could provide dose-dependent sedation , analgesia , anti-anxiety and inhibition of sympathetic nerves and other effects.” NCT02773017 ↗ “Studies showed dexmedetomidine (DEX) could improve surgical field, but the effect for functional nasal endoscopic surgery (FESS) was unclear.” NCT04276545 ↗ “Dexmedetomidine (DEX) has been shown to provide good perioperative haemodynamic stability with decreased intraoperative opioid requirements.” PMID 16914460 ↗ Aug 2006 “Dexmetedomidine (DEX) is a recent more selective α2 adrenergic agonist that has been used successfully during IVRA at a dose of 0.5µg/kg.” NCT05342870 ↗ “Dexmedetomidine (DEX) is a highly selective a2-agonist with sedative and analgesic effects and reduces sympathetic response to stimuli.” NCT03588988 ↗ “One potential treatment is dexmedetomidine (DEX), a highly selective α 2-adrenoreceptor agonist that is used as an anesthetic adjuvant.” PMID 32317860 ↗ Apr 2020 “The alpha-2 agonist dexmedetomidine (dex) has been approved for short-term sedation in surgical intensive care unit (ICU) patients.” NCT00641563 ↗ “Many studies have shown that dexmedetomidine (DEX) reduced the incidence of delirium after non-cardiac surgery in elderly patients.” PMID 36690404 ↗ Jan 2023 “This study evaluated the effectiveness of dexmedetomidine (Dex) and Ketamine as adjuvants in EOIPB for post-thoracotomy pain (PTP).” PMID 41299290 ↗ Nov 2025 “So, to overcome this flaw some adjuvants were proven to prolong the analgesia duration as Dexmetedomidine (Dex), and magnesium.” NCT04498351 ↗ “Dexmedetomidine (Dex) is a novel α2-adrenoceptor agonist that is primarily used in surgical anesthesia and conscious-sedation.” NCT02842437 ↗ “This research study is examining the absorption of the sedative dexmedetomidine (DEX) in the blood when given by nasal spray.” NCT02836431 ↗ “BACKGROUND: Buccal dexmedetomidine (DEX) produces adequate preoperative sedation and anxiolysis when used as a premedication.” PMID 32889844 ↗ Feb 2021 “Dexmedetomidine (DEX) has sedative, sympatholytic and analgesic effects and might be beneficial if used as an adjuvant” PMID 29678158 ↗ Apr 2018 “Dexmedetomidine (DEX) was administered during anesthesia and early postoperative period for patients in the DEX group” PMID 28182690 ↗ Feb 2017 “Dexmedetomidine (DEX) is a highly selective agonist that acts by binding with presynaptic alpha 2-adrenergic receptor” NCT06910644 ↗ “Dexmedetomidine (Dex) is a highly selective 2-adrenergic receptor agonist with significant analgesia affection.” NCT05500703 ↗ “Animal data have shown that dexmedetomidine (DEX) induces neuroprotective effects only at well-adjusted doses.” NCT05369949 ↗ “Dexmedetomidine (DEX) is known as a type of alpha agonist which can elongate the duration of regional block.” NCT04398589 ↗ “An alternative TIVA that is very commonly used for adult spine surgery is propofol + dexmedetomidine (DEX).” NCT06096181 ↗ “Dexmedetomidine (DEX), a selective alpha-2 agonist, has sympatholytic, sedative, and analgesic properties.” NCT02097407 ↗ “Its active molecule, Dexmedetomidine (Dex) is a selective and powerful agonist of α2-adrenoreceptors (AR).” NCT03151863 ↗ “The α2-adrenergic agonist dexmedetomidine (DEX) is a sedative and can be used as an adjunct to hypnotics.” PMID 32334510 ↗ Apr 2020 “Dexmedetomidine (DEX) is a selectiveα2 adrenergic receptor agonist with sedative and analgesic effects.” NCT07125573 ↗ “DEXMEDETOMIDINE (DEX), an alpha-2 adrenoreceptor agonist, is gaining popularity in neuroanesthesia.” NCT00335972 ↗ “Dex (Precedex, Dexmedetomidine HCl Injection) is produced by Pfizer Inc, NY, Ny (formerly Hospira).” NCT03355053 ↗ “Dexmedetomidine (Dex) is a selective α-2 adrenoreceptor agonist that can alleviate lung injury.” PMID 36166132 ↗ Sep 2022 “Dexmedetomidine (Dex) administration perioperatively might help to reduce the incidence of POD.” PMID 37743486 ↗ Sep 2023 “Dexmeditomidine (DEX) has been studied as adjuvant for nerve block to aumnet the pain reliefe.” NCT05624866 ↗ “Dexmedetomidine (DEX) is a specific alpha2 adrenergic agonist with promising data in NICU.” NCT07241351 ↗ “Dexmedetomidine (DEX), is a selective centrally acting α 2-adrenergic receptors agonist” NCT04709315 ↗ “Dexmedetomidine(Dex) is the only anesthetic which has sedative and analgesic effects.” NCT03095469 ↗ “Dexmedetomidine (DEX) sedation is widely used in deep brain stimulation implantation” NCT05376761 ↗ “Dexmedetomidine (Dex), a potent and highly selective α2-adrenergic receptor agonist” NCT06838650 ↗ “Dexmedetomidine(DEX) is a novel , highly selective α2 adrenergic receptor agonists” NCT02099253 ↗ “Dexmedetomidine (DEX), is a highly selective alpha2 adrenoceptor (α2-AR) agonist” PMID 35291989 ↗ Mar 2022 “Dexmedetomidine (DEX) offers non-opioid analgesia and opioid-sparing effects.” PMID 42207991 ↗ May 2026 “Dexmedetomidine (DEX) is a highly selective α-2 adrenergic receptor agonist.” NCT06352593 ↗ “Dexmedetomidine (Dex) is a highly selective α 2-adrenergic receptor agonist” NCT06619912 ↗ “Dexmedetomidine (DEX) for sublingual (SL) administration (BXCL501) - 40µg” NCT06335407 ↗ “administration of dexmedetomidine (DEX) can prolong analgesic duration.” PMID 26133711 ↗ 2015 “Dexmedetomidine (DEX) is a highly selective α2 adreno-receptor agonist” NCT05911776 ↗ “Dexmedetomidine (DEX) is a highly selective α2-adrenoceptor agonist” NCT04926454 ↗ “This research study is a continuation of a previous DEX PK study.” NCT03668951 ↗ “Dexmedetomidine (DEX), a selective α (2)-adrenoreceptor agonist.” NCT02720705 ↗ “Dexmedetomidine (DEX) is an a-2 adrenergic agonist for sedation.” NCT04674241 ↗ “Dexmedetomidine (DEX), a highly specific α2-adrenergic agonist” PMID 24627001 ↗ Mar 2014 “Dexmedetomidine (DEX), a selective α2-adrenoceptor agonist” NCT07538284 ↗ “bolus dexmedetomidine (DEX) is immediately discontinued” NCT05785689 ↗ “Dexmedetomidine (DEX) is an alpha-2 adrenergic agonist” NCT06551259 ↗ “among them Dexmedetomidine (DEX).” NCT03877120 ↗ “Drug: Dexmedetomidine (DEX)” NCT07556133 ↗ “Drug: Dexmedetomidine (DEX)” NCT07622355 ↗ “Drug: Dexmedetomidine (DEX)” NCT04912518 ↗ “Dexmedetomidine group (DEX)” NCT03827408 ↗ “Dexmedetomidine (DEX)” NCT07470775 ↗ “Dexmedetomidine (DEX)” NCT07475156 ↗ “dexmedetomidine (DEX)” NCT07072650 ↗ “Dexmedetomidine (DEX)” NCT07519863 ↗ |
| Known as | Dex,Dexmedetomidine | “Dex,Dexmedetomidine” NCT02552459 ↗ |
| Known as | DEX-IN | “DEX-IN (Intranasal dexmedetomidine) 50mcg every 6 hours for 48 hours.” NCT02284243 ↗ |
| Known as | Dexamed | “Dexmedetomidine (Dexamed) is a selective α2-adrenoceptor agonist with sedative and neuroprotective properties, known to reduce ICP without respiratory depression .” NCT07199595 ↗ |
| Known as | dexamedetomidine | “The needle entry point will be anesthetized with 20 mL 0.25% Rupivacane plus dexamedetomidine 0.25ug/kg.” NCT07368075 ↗ |
| Known as | Dexdomitor | “Dexmedetomidine Injectable Solution [Dexdomitor]” NCT05123170 ↗ |
| Known as | Dexdor | “Currently, two pharmacological α-2 agonists, clonidine (Catapressan®, Boehringer Ingelheim) and dexmedetomidine (Dexdor®, Orion Corporation), are marketed and commonly used in...” NCT04758936 ↗5“1 µg/kg dexmedetomidine (dexmedetomidine hydrochloride 100 microg/ml, Dexdor® Orion Oyj, Espoo, Finland) diluted in 10 ml of sodium chloride will be administered intravenously...” NCT02724098 ↗ “Dexmedetomidine group (Dex group) : Two administrations of 1 microg/kg of Dexdor® in 250 ml of sodium chloride during 30 min.” NCT03834129 ↗ “It is composed by Dexmedetomidine (Dexdor), Lidocaine, Magnesium Sulfate and ketamine (Ketolar).” NCT05887258 ↗ “Dexmedetomidine (Dexdor®)” NCT02096068 ↗ “Dexdor” NCT04266665 ↗ |
| Known as | Dexemedethomidine | “Dexemedethomidine is given as major sedative drug” NCT01091818 ↗ |
| Known as | DEXM | “Dexmedetomidine (DEXM) is a highly selective α2-adrenoceptor agonist that has been used increasingly in pediatric anesthesia.” NCT03791879 ↗ |
| Known as | Dexmedetmodine | “Dexmedetmodine 50mic (0.5ml) ,4 mg dexamethasone (1ml), 40 mg lidocaine 2% (2ml) added to 4ml total volume with sterile saline .” NCT05271721 ↗ |
| Known as | dexmedetomdine | “Transforaminal injection of chronic radicular lower limb injection by either dexmedetomdine or magnesuim sulfate” NCT05271721 ↗ |
| Known as | Dexmedetomedine | “The randomized control trial of Comparison of Ropivacane 0.25% plus Dexamethasone and Ropivacane 0.25% plus Dexmedetomedine will be conducted at department of anaesthesia of...” NCT07368075 ↗ |
| Known as | dexmedetomidin | “Drug: dexmedetomidin” NCT07166614 ↗ |
| Known as | dexmedetomidine HCl | “Effect of Sublingual Formulation of Dexmedetomidine HCl (BXCL501) on Ethanol in Heavy Drinkers With PTSD - Outpatient Study” NCT06335407 ↗1“BXCL501 (dexmedetomidine HCl) taken sublingually (under the tongue) in the ED and at bedtime over 2 weeks.” NCT06943404 ↗ |
| Known as | Dexmedetomidine HCl Injection | “Dex (Precedex, Dexmedetomidine HCl Injection) is produced by Pfizer Inc, NY, Ny (formerly Hospira).” NCT03355053 ↗ |
| Known as | Dexmedetomidine Hydrochloride | “1 µg/kg dexmedetomidine (dexmedetomidine hydrochloride 100 microg/ml, Dexdor® Orion Oyj, Espoo, Finland) diluted in 10 ml of sodium chloride will be administered intravenously...” NCT02724098 ↗39“Dexmedetomidine hydrochloride ,a relatively new drug in Chinais ,is a highly selective, potent a2-adrenoceptor agonist with significant analgesic, sedative and anxiolytic effects.” NCT01864187 ↗ “Dexmedetomidine hydrochloride as a single agent produces sedation, pain relief, anxiety redution, stable respiratory rates, and predictable cardiovascular responses.” NCT00691886 ↗ “Study drugs (either 200 μg/2 ml dexmedetomidine hydrochloride or 2 ml 0.9% saline) were provided as clear aqueous solution in the same type of 3 ml volume ampules” NCT03117790 ↗ “A single vial contains an injection solution with 2 mL of dexmedetomidine hydrochloride solution (100 µg/mL as dexmedetomidine) dissolved in physiological saline” NCT02757625 ↗ “Patients in the Opioid Sparing group will receive a dexmedetomidine (PRECEDEX™ "dexmedetomidine hydrochloride" - Pfizer) and ketamine.” NCT05674877 ↗ “Dexmedetomidine hydrochloride (Precedex®, manufactured by Hospira, Inc. Lake Forest, IL, and USA) is supplied in 100 μg/ml ampule.” NCT03064633 ↗ “The nasal spray group (Group D) trial medication specification is dexmedetomidine hydrochloride nasal spray at 25μg per spray.” NCT07579806 ↗ “Dexmedetomidine hydrochloride (PrecedexTM), presented in ampoule containing 2 mL of 100 mcg / mL solution for injection” NCT03290625 ↗ “dexmedetomidine (dexmedetomidine hydrochloride 100 μg/ml, Precedex® Abbott Laboratories North Chicago, IL 60064, USA)” NCT01084473 ↗ “Group 1 (LD) was administered 50 μg of dexmedetomidine hydrochloride nasal spray and 50 μg of placebo nasal spray” NCT07298525 ↗ “Use of Dexmedetomidine Hydrochloride 5 micrograms (1 mL) as an adjuvant with bupivacaine hydrochloride” NCT05993975 ↗ “Dexmedetomidine Hydrochloride is a novel highly-selective α2 adrenergic receptor agonist” NCT03346226 ↗ “100 mcg/mL dexmedetomidine hydrochloride; Precedex, Hospira Inc, Lake Forest, IL” NCT05775861 ↗ “Dexmedetomidine Hydrochloride: PrecedexR 200 µg/2ml vial , Pfizer, Egypt.” NCT06958367 ↗ “Dexmedetomidine Hydrochloride which is an Alfa 2 receptor agonist” NCT05850455 ↗ “Drug: Dexmedetomidine Hydrochloride 0.5 MG/ML” NCT06354478 ↗ “Drug: Dexmedetomidine Hydrochloride 0.1 MG/ML” NCT03817112 ↗ “Drug: Dexmedetomidine Hydrochloride 0.1 MG/ML” NCT04652427 ↗ “dexmedetomidine hydrochloride nasal spray” NCT07550881 ↗ “Precedex, dexmedetomidine hydrochloride” NCT04082767 ↗ “Drug: Dexmedetomidine Hydrochloride” NCT00142493 ↗ “Drug: Dexmedetomidine Hydrochloride” NCT03596424 ↗ “Drug: Dexmedetomidine Hydrochloride” NCT03312413 ↗ “Drug: Dexmedetomidine Hydrochloride” NCT04042727 ↗ “Drug: Dexmedetomidine Hydrochloride” NCT05342376 ↗ “Drug: Dexmedetomidine Hydrochloride” NCT04409964 ↗ “Drug: Dexmedetomidine Hydrochloride” NCT05489900 ↗ “Drug: Dexmedetomidine Hydrochloride” NCT04906889 ↗ “Drug: Dexmedetomidine Hydrochloride” NCT03234660 ↗ “Drug: Dexmedetomidine Hydrochloride” NCT04772222 ↗ “Drug: Dexmedetomidine Hydrochloride” NCT06720220 ↗ “Drug: Dexmedetomidine Hydrochloride” NCT03530371 ↗ “Drug: Dexmedetomidine Hydrochloride” NCT05175781 ↗ “Drug: Dexmedetomidine Hydrochloride” NCT06808295 ↗ “Drug: Dexmedetomidine Hydrochloride” NCT05552391 ↗ “Drug: Dexmedetomidine Hydrochloride” NCT06366412 ↗ |
| Known as | dexmedetomidine hydrochloride for injection | “dexmedetomidine hydrochloride for injection (200 ug/2 ml) will be diluted with normal saline to 50 ml (final dexmedetomidine concentration 4 ug/ml).” NCT03289325 ↗ |
| Known as | Dexmedetomidine Injection | “Dexmedetomidine Injection [Precedex]” NCT04659642 ↗2“Dexmedetomidine Injection [Precedex]” NCT06386783 ↗ “Drug: Dexmedetomidine injection” NCT06410365 ↗ |
| Known as | Dexmedetomidini hydrochloridum | “Active agent: Dexmedetomidinum ut Dexmedetomidini hydrochloridum. Route of administration: intravenous” NCT03844841 ↗ |
| Known as | Dexmedetomidinum | “Active agent: Dexmedetomidinum ut Dexmedetomidini hydrochloridum. Route of administration: intravenous” NCT03844841 ↗ |
| Known as | Dexmeditomidine | “Dexmeditomidine (DEX) has been studied as adjuvant for nerve block to aumnet the pain reliefe.” NCT05624866 ↗ |
| Known as | dexmedtemodine | “hyalase and dexmedtemodine are well known adjuvants given epidurally to alleviate chronic back pain.” NCT05370963 ↗1“epidural transforaminal injection of dexmedtemodine” NCT05271721 ↗ |
| Known as | Dexmetedomidine | “So, to overcome this flaw some adjuvants were proven to prolong the analgesia duration as Dexmetedomidine (Dex), and magnesium.” NCT04498351 ↗ |
| Known as | Dexmetomidine | “To Compare Post-op Analgesic Effectiveness of Ropivicaine+Dexamethasone and Ropivacane+Dexmetomidine in TAP Block in Stoma Reversal Under GA in Terms of Duration of Analgesia.” NCT07368075 ↗ |
| Known as | DEXTOMID | “Study drugs would be prepared as follow In group BD, 0.5% hyperbaric bupivacaine (ANAWIN heavy, Neon Laborotaries, India) 10mg (2ml) with addition of 5 mcg (0.2ml)...” NCT06367660 ↗ |
| Known as | DMET | “For many years, clonidine, an α2-adrenergic receptor (α2-AR) agonist, has been widely used as an analgesic adjuvant in perioperative conditions and pain therapy....” PMID 21283652 ↗ Dec 20101“Dexmedetomidine (DMET), a selective a2-adrenergic agonist” PMID 30824336 ↗ Jan 2019 |
| Known as | DMT | “BACKGROUND: Dexmedetomidine (DMT), a highly selective α2-adrenoceptor agonist, has been used safely as a sedative in patients under regional anesthesia.” PMID 25971886 ↗ Jan 20152“Dexmedetomidine (DMT) has been shown to prolong spinal anaesthesia.” PMID 22220945 ↗ Jan 2012 “dexmedetomidine (DMT)” NCT04772222 ↗ |
| Known as | DMTS | “The primary objective of this study is to evaluate the analgesic efficacy of Dexmedetomidine Transdermal System (DMTS), compared with placebo, in participants following abdominoplasty.” NCT04242407 ↗1“Dexmedetomidine Transdermal System (DMTS) for Post-Operative Analgesia Following Bunionectomy” NCT02953054 ↗ |
| Known as | DXM | “Dexmedetomidine(DXM), a selective 2-adrenoreceptor agonist, has been used in the epidural space in humans without any reports of neurological deficits.” NCT01342562 ↗5“Dexmedetomidine (DXM) loading dose of 0.6 µg/kg followed by DXM infusion given at a rate of 0.4 ml/kg/h and was provided as 0.15 µg/kg/h for 24-h PO.” NCT06907277 ↗ “Dexmedetomidine (DXM) a highly selective α2 adrenergic agonist with sedative, anxiolytic, analgesic, sympatholytic and antihypertensive effects.” NCT06837844 ↗ “Dexmedetomidine (DXM) is a selective α2-adrenergic agonist with analgesic properties.” NCT06685081 ↗ “Dexmedetomidine (DXM) is a potent and highly selective α2-adrenergic agonist” NCT06470854 ↗ “Dexmedetomidine (DXM) is a recently released and approved alpha 2 agonist” NCT02102139 ↗ |
| Known as | Hydrochloric acid right-metomidine | “Hydrochloric acid right-metomidine is an alpha2-adrenaline receptor agonisant developed by Orion Pharma (Finland) and Abott (Usa) in collaboration.” NCT04652427 ↗ |
| Known as | Igalmi | “Sublingual film containing 180 µg of Igalmi (dexmedetomidine)” NCT06041646 ↗ |
| Known as | IgalmiTM | “BXCL501 (120 and 180 mcg: IgalmiTM) was recently FDA approved for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder in adults.” NCT05712707 ↗ |
| Known as | IN DEX | “Recently we have introduced Intra-nasal Dexmedetomidine (IN DEX), with an initial impression of much improved drug acceptance and possibly improved efficacy over TFS.” NCT04270708 ↗1“Subjects will be administered 1 mcg/kg or 1.5 mcg/kg intranasal dexemdetomidine (IN-DEX) and monitored for up to 5 hours.” NCT02211118 ↗ |
| Known as | Percedex | “The Patients will receive hypotensive anesthesia via I .V infusion with dexmedetomidine (Percedex )” NCT03892512 ↗ |
| Known as | Precedex | “35 patients will be received dexmedetomidine (Precedex; Abbott Laboratories, North Chicago, Illinois, USA) (vial = 2 ml) 100 mcg/ml at bolus dose of 1 mcg /kg slowly infused...” NCT05703048 ↗84“The patients received loading dose of dexmedetomidine (1 μg/kg) (Precedex, Abbot Laboratories Inc., Abbot Park, IL, USA) intravenously over 15 minutes before induction of...” NCT06052111 ↗ “Patients with COPD scheduled for outpatient FB will be provided with an intravenous infusion of dexmedetomidine (1 mcg/kg/hr) (Precedex®: Hospira, Inc, Lake Forest, IL) over a...” NCT00401206 ↗ “Dexmedetomidine 0.25 µg/kg loading dose will be infused intravenously over 10 minutes through syringe pump before surgery in the control group (Prepared using Precedex vial...” NCT04658732 ↗ “Patients will receive dexmedetomidine (Precedex®; 200 µg/2 ml; at one µg/kg loading dose over 10 minutes followed by a 0.5 µg/kg/hr. maintenance dose for 48 hours...” NCT06490731 ↗ “The purpose of this study is to see if the drug, Dexmedetomidine (also known as Precedex), can reduce pain for patients having Thoracic Surgery and therefore reduce the amount...” NCT01973452 ↗ “a loading dose of 1µg/kg of dexmedetomidine (precedex) made to 50 ml using normal saline will be given over 10 minutes followed by infusion of dexmedetomidine with a dose of...” NCT04148599 ↗ “Dexmedetomidine (Precedex) is a highly selective alpha 2 adrenoreceptor agonist which produce sedation, anxiolysis, analgesia, and decreasing inflammatory response to...” NCT06514040 ↗ “Dexmedetomidine (Precedex) is a highly selective α2-adrenergic agonist with the properties of analgesia, sedative, anxiolytic and neuroprotection without significant...” NCT07398066 ↗ “will have a bolus of dexmedetomidine one μg/kg (Precedex; Hospira, Inc, Lake Forest, IL) administered for 10 minutes, followed by a continuous infusion at 0.7 μg • kg-1 • h-1 during FOI” NCT04426552 ↗ “Dexmedetomidine (precedex®) will be administered by intranasal route in 1ug/kg each dose, repeating at most 3 times to see if it can give enough sedation to painful procedure.” NCT04621110 ↗ “Dexmedetomidine (D) group, where Dex. (Precedex, hospira, Egypt) 0.8 μg/kg was given intravenously over 10 min as a loading dose, and then infused at a rate of 0.4 μg/kg/h;” NCT05271253 ↗ “Dexmedetomidine group: the patients will receive deliberate hypotensive anesthesia with dexmedetomidine infusion (precedex ® 200 μg/2 ml; Hospira, Inc., Rocky Mount, USA)” NCT06752863 ↗ “Dexmedetomidine (Precedex, Meditera, USA) was administered at a loading dose of 1 µg/kg for 10 minutes before local anesthesia to be applied to the eye by the surgeon.” NCT04935541 ↗ “Group B will be injected with 20 ml of 0. 25% bupivacaine in each side added to it dexmedetomidine 0.5 μg/kg; (Precedex 100 μg/ml (Hospira, inc, lake forest, USA).” NCT04748224 ↗ “Dexmedetomidine used was preservative-free dexmedetomidine (Precedex, 2ml ampoule,100 ug /ml, Hospira, Inc, Rocky Mount, USA) in a concentration of 100 μg/mL.” NCT06389318 ↗ “0.5 mg/kg of dexmedetomidine (Precedex; Hospira, Lake Forest, IL) is mixed in normal saline 100mL and administered for 5 minutes after anesthetic induction.” NCT03468062 ↗ “Patients of group A will start dexmedetomidine (precedex 100 ug lmL, Hospira) infusion 0.4 ug {Kg}h after bolus of 0.5 ug 1 kg intravenously over 10 min” NCT04976374 ↗ “The aim of our study is to use an infusion of dexmedetomidine (Precedex) to aid in pain management in patients presenting with 3 or more rib fractures.” NCT05321121 ↗ “a bolus dose of 0.5mcg/kg dexmedetomidine was injected intravenously 5 minutes before the start of the procedure (Precedex®, Abbott, Istanbul, Turkey).” NCT01920113 ↗ “then dexmedetomidine (precedex 200 micrograms per 2ml, Abbott laboratories, Abbott park, IL, USA) which will be prepared in concentration 1μg/ml.” NCT03885804 ↗ “Initial sedation was employed with a 1 mg kg-1min-1 loading dose of dexmedetomidine (Precedex®,Hospira Inc, Rocky Mountain, USA) for 10 minutes.” NCT01789385 ↗ “200 μg of dexmedetomidine \[Precedex®, Pfizer\] is diluted with normal saline in a 50 mL syringe, resulting in a final concentration of 4 μg/mL.” NCT07389096 ↗ “Group T receiving 5 µg of dexmedetomidine (Precedex® 100 µg/mL, Hospira, Inc., IL, U.S.A.) combined with 12.5 mg of 0.5% hyperbaric bupivacaine” NCT04374318 ↗ “30 patients received a loading dose of 1 μg/kg dexmedetomidine (Precedex; Hospira, Precedex 200 mcg/2 ml, Hospira. Inc, Lake Forest, USA)” NCT03078946 ↗ “Dexmedetomidine (Precedex, 100 µg/ml; Rewine Pharmaceutical; Varachha, Seurat, Gujarat) was administered before induction of anesthesia” NCT06835010 ↗ “Patients in the Opioid Sparing group will receive a dexmedetomidine (PRECEDEX™ "dexmedetomidine hydrochloride" - Pfizer) and ketamine.” NCT05674877 ↗ “Dexmedetomidine hydrochloride (Precedex®, manufactured by Hospira, Inc. Lake Forest, IL, and USA) is supplied in 100 μg/ml ampule.” NCT03064633 ↗ “One prospect is dexmedetomidine (Precedex®), which is FDA-approved for short-term (≤24 hours) sedation in the intensive care unit.” NCT01007773 ↗ “Dexmedetomidine (Precedex) loadings of 1 μg/kg , then continuously at a rate of 0.2 μg/(kg/h) till the end of the operation .” NCT06355960 ↗ “(Dexmedetomidine group) Continuous IV Precedex™ using infusion pump (Terufusion TE-311, Terumo, Tokyo, Japan) during surgery” NCT03960775 ↗ “Dexmedetomidine is a sedative medication used mostly in intensive care units,and is marketed under the brand name Precedex.” NCT01070680 ↗ “patients will receive plus 0.5 µg/kg of dexmedetomidine (Precedex® 100 µg/ml) diluted in 2 ml of normal saline at each side” NCT06720337 ↗ “5 μg Dexmedetomidine (Precedex; Abbott; Chicago, IL, USA, 100 μg/ml diluted with normal saline solution (NSS) to 10 μg/ml)” NCT06654531 ↗ “dexmedetomidine (dexmedetomidine hydrochloride 100 μg/ml, Precedex® Abbott Laboratories North Chicago, IL 60064, USA)” NCT01084473 ↗ “Dexmedetomidine (Precedex®) for Severe Alcohol Withdrawal Syndrome (AWS) and Alcohol Withdrawal Delirium (AWD)” NCT01362205 ↗ “Dexmedetomidine (Precedex, 100 µg/ml) was provided as an intravenous (IV) loading dose of 1 µg/kg over 10-min” NCT06614881 ↗ “a single medication, dexmedetomidine (precedex) for the purpose of sedation prior to intubation in neonates” NCT05304598 ↗ “Dexmedetomidine(precedex 100mc/ml 1 mcg Pfizer com) will be injected IV before Induction of anesthesia.” NCT07074262 ↗ “Precedex (Dexmedetomidine) intervention: Intravenous administration of 1mcg/kg over 40 minutes.” NCT02856594 ↗ “Intranasal dexmedetomidine 100 mcg/mL (Precedex, Pfizer) 1 mcg/kg (max 100 mcg or 1 mL).” NCT03957304 ↗ “Adjunct Dexmedetomidine (Precedex®) Therapy Impact on Sedative and Analgesic Requirement” NCT00852046 ↗ “Dexmedetomidine (Precedex), a potent and highly selective α-2 adrenoceptor agonist” NCT07434206 ↗ “100 mcg/mL dexmedetomidine hydrochloride; Precedex, Hospira Inc, Lake Forest, IL” NCT05775861 ↗ “1 μg/kg dexmedetomidine (Precedex 4 mcg/ml, Pfizer. Inc, New York, USA)” NCT06464263 ↗ “dexmedetomidine (Precedex; Ho-Spira Inc., Lake Forest, Illinois, USA” NCT06017167 ↗ “Levobupivacaine(chirocaine) plus dexmedetomidine(precedex)” NCT04729868 ↗ “Dexmedetomidine (Precedex, Hospira, Lake forest, IL, USA)” NCT02843698 ↗ “Dexmedetomidine Hydrochloride 'Precedex' combined with” NCT05850455 ↗ “Precedex (Dexmedetomidine) 200 MCG in 2 ML Injection” NCT06414395 ↗ “dexmedetomidine (Precedex, 100 μg/ml, Hospira, USA)” NCT07513935 ↗ “Drug: Dexmedetomidine Injection [Precedex]” NCT05004519 ↗ “Drug: Dexmedetomidine Injection [Precedex]” NCT04730375 ↗ “Precedex, dexmedetomidine hydrochloride” NCT04082767 ↗ “Dexmedetomidine 0.004 MG/ML [Precedex]” NCT05099055 ↗ “Dexmedetomidine Injection [Precedex]” NCT04659642 ↗ “Dexmedetomidine Injection [Precedex]” NCT06867302 ↗ “Dexmedetomidine Injection [Precedex]” NCT06386783 ↗ “Dexmedetomidine Injection [Precedex]” NCT06386770 ↗ “Dexmedetomidine Injection [Precedex]” NCT04661475 ↗ “Dexmedetomidine Injection [Precedex]” NCT05689242 ↗ “Dexmedetomidine Injection [Precedex]” NCT03632460 ↗ “Dexmedetomidine Injection [Precedex]” NCT03738059 ↗ “Dexmedetomidine Injection [Precedex]” NCT05892705 ↗ “Dexmedetomidine Injection [Precedex]” NCT05788393 ↗ “Dexmedetomidine Injection [Precedex]” NCT04285255 ↗ “Dexmedetomidine Injection [Precedex]” NCT03989609 ↗ “Dexmedetomidine Injection [Precedex]” NCT03063073 ↗ “Dexmedetomidine Injection [Precedex]” NCT06103721 ↗ “Dexmedetomidine Injection [Precedex]” NCT03778671 ↗ “Dexmedetomidine Injection [Precedex]” NCT06090955 ↗ “Dexmedetomidine (Precedex) Infusion” NCT00363935 ↗ “Drug: Dexmedetomidine (Precedex)” NCT07202624 ↗ “Dexmedetomidine (Precedex®)” NCT02475824 ↗ “Dexmedetomidine (Precedex®)” NCT07443163 ↗ “Precedex (Dexmedetomidine)” NCT00561678 ↗ “Dexmedetomidine [Precedex]” NCT04213833 ↗ “Precedex” NCT02707809 ↗ |
| Known as | Precedex (dexmedetomidine hydrochloride; Pfizer Inc, NY, Ny) | “Precedex (dexmedetomidine hydrochloride; Pfizer Inc, NY, Ny)” NCT03355053 ↗ |
| Known as | Precedex, dexmedetomidine HCl | “Precedex, dexmedetomidine HCl” NCT01915277 ↗ |
| Known as | PrecedexR | “Dexmedetomidine Hydrochloride: PrecedexR 200 µg/2ml vial , Pfizer, Egypt.” NCT06958367 ↗ |
| Known as | PrecedexTM | “Group D patients (n = 30) will be administer 0.5 mcg/kg dexmedetomidine (PrecedexTM; Hospira Inc., Lake Forest, IL, USA) intravenously over 10 min.” NCT06712186 ↗2“Dexmedetomidine hydrochloride (PrecedexTM), presented in ampoule containing 2 mL of 100 mcg / mL solution for injection” NCT03290625 ↗ “The study drug dexmedetomidine (PrecedexTM) is supplied as dexmedetomidine HCL 200mcg/vial (100mcg/ml).” NCT03451227 ↗ |
| Known as | precidex | “Inj. Dexmedetomidine (precidex) 200/mcg/2ml given to participants in infusion form for 10 mins of surgery and maintenance dose given till the end of surgery” NCT05337085 ↗1“Inj.Dexmedetomidine(precidex ) 200mcg/2ml Given to participants in infusion form for 24 hours” NCT05264077 ↗ |
| Action | Activate | “dexmedetomidine (an alpha2 adrenoceptor agonist)” PMID 20233428 ↗ Mar 2010 |
| Modality | Other / unclassified | “a potent alpha2 adrenoceptor agonist” NCT01569048 ↗ |
| Route | Intravenous | “Intravenous Dexmedetomidine With Propofol/Midazolam” NCT00226785 ↗ |
| Target | ADRA2A | “a highly selective α2A-adrenergic receptor (ADRA2A) agonist” PMID 31168973 ↗ Jul 2019 |