Long-acting Parasternal Blocks for Analgesia After Cardiac Surgery

NCT05191745 ↗

Phase 3 Completed 60 enrolled Jewish General Hospital

RandomizedParallel-groupQuadruple-blindPrevention

Summary

This is a randomized, double-blind, controlled clinical trial is to evaluate the duration of efficacy of parasternal blocks with the use of local anesthetic adjuncts for analgesia after coronary artery bypass grafting surgery.

Timeline

Start: 2022-01-26
Primary completion: 2023-04-28
Completion: 2024-06-01

Publications

Cameron MJ, Long J, Yang SS, Kardash K. How Many Patients Are Needed to Detect a Difference in Pain With Parasternal Blocks? Anesth Analg. 2025 Jul 1;141(1):210-211. doi: 10.1213/ANE.0000000000007355. Epub 2024 Dec 17. No abstract available.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Bupivacaine	Other / unclassified	0.25 %	Other
Subject	Dexamethasone	Small molecule	5 mg	Other
Subject	Dexmedetomidine	Other / unclassified	50 ug	Other
Subject	Epinephrine	Other / unclassified	—	Other

Indications

No indication recorded.