Drugs / Dexamethasone
last change 2 days ago re-read 8 days ago

Dexamethasone

Small molecule targets HDAC2 via activation

Developed for
plasma cell myeloma · lymphoma · diabetic macular edema · leukemia · refractory plasma cell neoplasm · cataract · acute lymphoblastic leukemia · mantle cell lymphoma
+490 more · COVID-19 · macular retinal edema · neuropathy, painful · non-Hodgkin lymphoma · AL amyloidosis · extranodal nasal NK/T cell lymphoma · autoimmune thrombocytopenia · dry eye syndrome · osteoarthritis, knee · prostate cancer · Waldenstrom macroglobulinemia · lymphoblastic lymphoma · pulpitis · radiculopathy · smoldering plasma cell myeloma · chronic pain syndrome · diffuse large B-cell lymphoma · retinal vein occlusion · acute respiratory distress syndrome · amyloidosis · Hodgkins lymphoma · B-cell acute lymphoblastic leukemia · Meniere disease · non-small cell lung carcinoma · autoimmune thrombocytopenic purpura · cancer · chemotherapy-induced toxicity · cystoid macular edema · headache disorder · impacted teeth, multiple · peripheral T-cell lymphoma, not otherwise specified · plasma cell leukemia · T-cell non-Hodgkin lymphoma · acute myeloid leukemia · age-related macular degeneration · lumbar disk disease · adult acute lymphoblastic leukemia · anterior uveitis · arthropathy · asthma · hemophagocytic syndrome · light chain deposition disease · migraine disorder · myelodysplastic syndrome · obstructive sleep apnea syndrome · osteoarthritis · osteoarthritis, hip · pneumonia · preretinal fibrosis · primary systemic amyloidosis · rotator cuff syndrome · sciatica · bronchiolitis · Burkitt lymphoma · choroidal neovascularization · chronic lymphocytic leukemia/small lymphocytic lymphoma · classic Hodgkin lymphoma · keratoconus · mature T-cell and NK-cell non-Hodgkin lymphoma · metastatic malignant neoplasm in the brain · primary central nervous system lymphoma · acquired aneurysmal subarachnoid hemorrhage · ataxia telangiectasia · bronchopulmonary dysplasia · childhood acute lymphoblastic leukemia · delirium · diabetic retinopathy · follicular lymphoma · glaucoma · high grade B-cell lymphoma · lung cancer · MALT lymphoma · metastatic malignant neoplasm · POEMS syndrome · poisoning · precursor B-cell acute lymphoblastic leukemia · respiratory distress syndrome in premature infants · vertebral column disorder · vision disorder · acute asthma · acute leukemia · adult T-cell leukemia/lymphoma · anaplastic large cell lymphoma · arthritis, sacroiliac · B-cell childhood acute lymphoblastic leukemia · blepharitis · cataract 50 with or without glaucoma · central retinal vein occlusion · chronic conjunctivitis · colorectal cancer · conjunctivitis · epicondylitis · glioblastoma · graft versus host disease · Graves disease · head and neck cancer · heart failure · hypotensive disorder · kidney failure · lumbar spinal stenosis · metastatic prostate carcinoma · monoclonal gammopathy · newborn respiratory distress syndrome · nodal marginal zone B-cell lymphoma · occlusion of tributary of retinal vein · plasmacytoma · post-traumatic stress disorder · posterior uveitis · prostate adenocarcinoma · radiation-induced disorder · splenic marginal zone lymphoma · sudden hearing loss disorder · sudden sensorineural hearing loss · tinnitus · uveal melanoma · viral pneumonia · acne · acute bronchiolitis · acute conjunctivitis · acute otitis externa · acute respiratory failure · acute undifferentiated leukemia · adolescent idiopathic scoliosis · adult acute respiratory distress syndrome · allergic disease · anemia · angioimmunoblastic T-cell lymphoma · aortic valve disorder · arthritic joint disease · B-cell adult acute lymphocytic leukemia · B-cell non-Hodgkin lymphoma · B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2) · bacterial conjunctivitis · blast phase chronic myelogenous leukemia, BCR-ABL1 positive · brain cancer · bullous keratopathy · CD4+/CD56+ hematodermic neoplasm · central retinal vein occlusion with macular edema · childhood onset asthma · chronic graft versus host disease · congenital adrenal hyperplasia · corneal edema · coronary artery disorder · Crohn disease · croup · cysticercosis · dengue disease · dermatitis · disease of bone structure · disease of the tendon · disease related to hematopoietic stem cell transplant · eye adnexa disorder · eye allergy · female breast carcinoma · Fuchs' endothelial dystrophy · hearing loss disorder · hematopoietic and lymphoid system neoplasm · hepatocellular carcinoma · hepatosplenic T-cell lymphoma · Hodgkin's lymphoma, lymphocytic depletion · Hodgkin's lymphoma, mixed cellularity · ileus · infertility disorder · inflammatory bowel disease · intermediate uveitis · Langerhans cell histiocytosis · Lassa fever · lichen planus, oral · lymphoid leukemia · malignant glioma · mixed phenotype acute leukemia · nervous system disorder · neuritis · nodular sclerosis classical Hodgkin lymphoma · non-infectious anterior uveitis · ovarian carcinoma · pemphigus · peripheral arterial disease · pharyngitis · plasma cell neoplasm · platinum-induced ototoxicity · pleural empyema · precursor lymphoblastic lymphoma/leukemia · pregnancy disorder · primary cutaneous B-cell lymphoma · pterygium · respiratory failure · retinal detachment · rheumatic fever · secondary hemophagocytic lymphohistiocytosis · shoulder impingement syndrome · sinus histiocytosis with massive lymphadenopathy · Sjogren syndrome · solitary osseous plasmacytoma · status asthmaticus · stomatitis · subjective cognitive decline · T-cell acute lymphoblastic leukemia · thrombocytopenia · tonsillitis · traumatic encephalopathy · triple-negative breast carcinoma · venous thromboembolism · wet macular degeneration · Acanthamoeba keratitis · acute apical periodontitis · acute kidney injury · acute pancreatitis · aggressive NK-cell leukemia · ALK-negative anaplastic large cell lymphoma · altitude sickness · anal fistula · anogenital human papillomavirus infection · anosmia · anterior scleritis · aphthous stomatitis · atopic eczema · atrial fibrillation · atrioventricular block · autoimmune lymphoproliferative syndrome · avascular necrosis · B-cell chronic lymphocytic leukemia · B-cell lymphoma, unclassifiable, with features intermediate between diffuse large b-cell lymphoma and classical Hodgkin lymphoma · B-lymphoblastic leukemia/lymphoma with hypodiploidy · bacterial vaginosis · Bell's palsy · benign prostatic hyperplasia · benign shuddering attacks · beta thalassemia · bilineal acute myeloid leukemia · bone disorder · borderline epithelial tumor of ovary · brain edema · breast disorder · bursitis · carbon monoxide-induced delayed encephalopathy · carbon monoxide-induced parkinsonism · cardiac arrest · carpal tunnel syndrome · castration-resistant prostate carcinoma · cellulitis · central nervous system non-hodgkin lymphoma · cervical disk degenerative disorder · cervical lymphadenitis · chemotherapy-induced oral mucositis · cholangiolocellular carcinoma · chronic obstructive pulmonary disease · chronic rhinosinusitis · cirrhosis of liver · classic congenital adrenal hyperplasia · classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency · cluster headache syndrome · Coats disease · colorectal adenocarcinoma · congenital heart block · congenital heart defects, multiple types · congenital temporomandibular joint ankylosis · congestive heart failure · corneal disorder · corneal endothelial dystrophy · Cryptococcal meningitis · cryptorchidism · depressive disorder · developmental dysplasia of the hip · discharging ear · drug-induced hearing loss · endometrioid tumor · enterocolitis · enteropathy-associated T-cell lymphoma · Epstein-Barr virus infection · esophagitis · extramedullary plasmacytoma · extramedullary soft tissue plasmacytoma · exudative vitreoretinopathy · eye disorder · female infertility · fibromyalgia · focal segmental glomerulosclerosis · frozen shoulder · gallbladder disorder · gastric neoplasm · glomerulonephritis · grade III lymphomatoid granulomatosis · Hashimoto thyroiditis · HELLP syndrome · hemangioma · hematologic disorder · hematopoietic and lymphoid cell neoplasm · hemorrhoid · hepatitis B virus infection · hernia, double inguinal · herpes simplex encephalitis · high altitude pulmonary edema · high grade malignant neoplasm · high-grade B-cell lymphoma double-hit/triple-hit · hormone-resistant prostate carcinoma · hyperbilirubinemia · hypersensitivity reaction disease · hypospadias · idiopathic multicentric Castleman disease · immune reconstitution inflammatory syndrome · infectious disease · infectious disease with sepsis · inflammatory disease · interstitial lung disease · intestinal obstruction · intracerebral hemorrhage · intracranial hypotension · intrahepatic cholangiocarcinoma · intraocular lymphoma · ischemic stroke · lacrimal apparatus disorder · large-cell immunoblastic lymphoma · laryngeal disorder · leiomyoma · leptospirosis · lichen planus · light and heavy chain deposition disease · limb ischemia · liver cancer · liver disorder · liver failure · low grade glioma · lung disorder · macular degeneration · mastoiditis · meningeal tuberculosis · meningioma · metastasis from malignant tumor of colon · metastatic malignant neoplasm in the spinal cord · metastatic neoplasm · migraine with aura · migraine without aura · mixed phenotype acute leukemia, B/myeloid · mixed phenotype acute leukemia,T/myeloid · mouth disorder · mucositis · mycosis fungoides and variants · myelodysplastic/myeloproliferative disease · myeloproliferative neoplasm · myofascial pain syndrome · neoplasm of mediastinum · nephrosis · nephrotic syndrome · neuralgia · nodular lymphocyte predominant Hodgkin lymphoma · noise induced hearing loss · nutritional deficiency disease · obstetric disorder · obstructive lung disease · ocular hypertension · odontogenic cyst · open-angle glaucoma · opsoclonus-myoclonus syndrome · orbital cellulitis · Osgood-Schlatter disease · otitis media · otomycosis · ovarian clear cell tumor · ovarian hyperstimulation syndrome · ovarian serous tumor · palmar fibromatosis · panuveitis · paralytic ileus · pericarditis · peripheral nerve lesion · peripheral neuropathy · persistent tachypnoe of infancy · phacoanaphylactic uveitis · plantar fasciitis · post-cardiac arrest syndrome · post-transplant lymphoproliferative disease · postoperative ventricular dysfunction · preterm premature rupture of the membranes · primary plasmacytoma of the bone · primary thrombocytopenia · pulmonary immaturity · pure red-cell aplasia · radial heads, posterior dislocation of · refractive error · relapsing-remitting multiple sclerosis · respiratory syncytial virus bronchiolitis · respiratory tract infectious disorder · retinal edema · retinal lattice degeneration · retinal perforation · rhegmatogenous retinal detachment · rheumatic disorder · rheumatic heart disease · rosacea conjunctivitis · sarcoidosis · senile cataract · sensorineural hearing loss disorder · severe acute respiratory syndrome · sickle cell disease · sleep disorder · small intestine lymphoma · spinal stenosis · spondylosis · stenosis of lacrimal punctum · subarachnoid hemorrhage · subcutaneous panniculitis-like T-cell lymphoma · Sydenham chorea · T-cell adult acute lymphocytic leukemia · T-cell and NK-cell neoplasm · temporomandibular joint disorder · temporomandibular joint dysfunction syndrome · testicular lymphoma · thrombocytopenia due to immune destruction · thrombocytopenic purpura · thyroid gland disorder · tinea infection · traumatic brain injury · trigeminal neuralgia · type 1 diabetes mellitus · urinary bladder disorder · urticaria · uveitis · vestibular disorder · viral conjunctivitis · vitiligo · voice disorders · xerophthalmia · acute pharyngitis · aggressive B-cell non-Hodgkin lymphoma · alcohol dependence · anaphylaxis · aorta coarctation · autoinflammatory syndrome · BD syndrome · blepharoconjunctivitis · bone neoplasm · calcific tendinitis · cerebral toxoplasmosis · chalazion · chorioretinitis · cleft lip · conjunctival pterygium · de Quervain disease · dental pulp disorder · disorder of facial skeleton · early T cell progenitor acute lymphoblastic leukemia · eclampsia · endophthalmitis · epiphora due to excess lacrimation · esophageal cancer · generalized vitiligo · glioma · gout · high grade astrocytic tumor · hyperhidrosis palmaris ET plantaris · indomethacin embryofetopathy · influenza · inherited hemoglobinopathy · intervertebral disk degenerative disorder · intestinal perforation · keloid · keloid formation · keratitis · keratoconjunctivitis · meralgia paresthetica · mucous membrane pemphigoid · myopathy · oral cavity cancer · parathyroid gland disorder · pemphigus vulgaris · persistent idiopathic facial pain · post-surgical hypoinsulinemia · postherpetic neuralgia · primary angle-closure glaucoma · primary bacterial infectious disease · proliferative diabetic retinopathy · proliferative vitreoretinopathy · psoriasis · radiculitis · reactive airway disease · refractory hematologic cancer · renal fibrosis · respiratory system disorder · scorpion envenomation · sinusitis · skin infection · tibial collateral ligament bursitis · tick-borne encephalitis · trigger thumb · urinary tract infection · urinary tract obstruction · vernal keratoconjunctivitis · vestibular neuronitis · viral encephalitis
Investigated by
National Cancer Institute (NCI) · Celgene Corporation · M.D. Anderson Cancer Center · Allergan · Ocular Therapeutix, Inc. · Mayo Clinic
+1,320 more · Bristol-Myers Squibb · Amgen · Millennium Pharmaceuticals, Inc. · PETHEMA Foundation · Memorial Sloan Kettering Cancer Center · Assiut University · Dana-Farber Cancer Institute · Takeda · Children's Oncology Group · Emory University · Peking University People's Hospital · SWOG Cancer Research Network · Sanofi · Sun Yat-sen University · Weill Medical College of Cornell University · Institute of Hematology & Blood Diseases Hospital, China · Janssen, LP · Karyopharm Therapeutics Inc · University Health Network, Toronto · University of Chicago · AbbVie · Alliance for Clinical Trials in Oncology · Massachusetts General Hospital · Merck Sharp & Dohme LLC · Roswell Park Cancer Institute · Shandong University · University of Arkansas · Duke University · Peking Union Medical College Hospital · Samsung Medical Center · Yonsei University · Ain Shams University · Janssen Scientific Affairs, LLC · Nantes University Hospital · Novartis Pharmaceuticals · Seoul National University Hospital · St. Jude Children's Research Hospital · Assistance Publique - Hôpitaux de Paris · Cairo University · Chinese Academy of Medical Sciences · European Myeloma Network B.V. · Hospital for Special Surgery, New York · Janssen Research & Development, LLC · Otonomy, Inc. · Pfizer · The First Affiliated Hospital of Soochow University · The University of Hong Kong · University of Alabama at Birmingham · Barbara Ann Karmanos Cancer Institute · Beijing Tiantan Hospital · Eyegate Pharmaceuticals, Inc. · Fondazione EMN Italy Onlus · Fred Hutchinson Cancer Center · Janssen Pharmaceuticals · Johns Hopkins University · Multiple Myeloma Research Consortium · National Institute of Allergy and Infectious Diseases (NIAID) · Poznan University of Medical Sciences · Quince Therapeutics S.p.A. · Rigshospitalet, Denmark · University of Miami · Wake Forest University Health Sciences · Brigham and Women's Hospital · Eli Lilly and Company · French Innovative Leukemia Organisation · Genentech, Inc. · GlaxoSmithKline · H. Lee Moffitt Cancer Center and Research Institute · Intergroupe Francophone du Myelome · Montefiore Medical Center · National Heart, Lung, and Blood Institute (NHLBI) · OHSU Knight Cancer Institute · Tanta University · University Hospital, Toulouse · all 1,326 on the full record

Regulatory milestones approvals, filings & regulatory actions · 7 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Label expansions (3) US (FDA) DEXTENZA — 2019-06-20 – 2025-04-07 fda.gov ↗
Label expansions (2) US (FDA) OZURDEX — 2010-09-24 – 2014-06-28 fda.gov ↗
Approved EU (EMA) Ozurdex — 2010-07-26 europa.eu ↗
Approved US (FDA) DECADRON — 1958-10-30 fda.gov ↗

Trials 1,755 · started per year

today
US approved 1958
EU approved 2010
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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 031 trials · 2 met primary · 1 missed
Phase 0 NCT07662200 Aug 2026 → Aug 2027 expected malignant germ cell tumor Ottawa Hospital Research Institute Not yet recruiting No outcome recorded
Phase 0 NCT07343817 Jul 2026 → Apr 2028 expected — Ahmed Nassar Ibrahim Mohammed Not yet recruiting No outcome recorded
Phase 0 NCT07812259 May 2026 → Jun 2027 expected parotid gland neoplasm Nîmes University Hospital Recruiting No outcome recorded
Phase 0 NCT07109258 May → Sep 2025 overdue — Cairo University Recruiting No outcome recorded
Phase 0 NCT06428630 May 2025 → Sep 2026 lichen planus, oral Tufts University Withdrawn No outcome recorded
Phase 0 NCT06894069 Mar → May 2025 overdue — University of Jordan Not yet recruiting No outcome recorded
Phase 0 NCT06432712 Jan 2025 — Shoaib Rahim Unknown No outcome recorded
Phase 0 NCT06142396 Nov 2024 → Nov 2027 expected kidney failure, plasma cell myeloma Augusta University Recruiting No outcome recorded
Phase 0 NCT06556095 Sep 2024 → Jan 2026 — The University of Texas Health Science Center at San Antonio Completed No outcome recorded
Phase 0 NCT05994183 Oct 2023 → Mar 2025 bronchiolitis IDeA States Pediatric Clinical Trials Network Withdrawn No outcome recorded Stop: Enrollment
Phase 1118 trials · 3 met primary · 1 missed
Phase 1 NCT07341867 Aug 2026 → Mar 2028 expected plasma cell myeloma, triple-negative breast carcinoma Andrew Hantel, MD Not yet recruiting No outcome recorded
Phase 1 NCT07513129 Jun 2026 → Dec 2029 expected T-cell acute lymphoblastic leukemia M.D. Anderson Cancer Center Recruiting No outcome recorded
Phase 1 NCT07426042 Apr → May 2026 overdue — Min Kyu Park Not yet recruiting No outcome recorded
Phase 1 NCT07224334 Dec 2025 → Dec 2027 expected diabetes mellitus David D'Alessio, M.D. Recruiting No outcome recorded
Phase 1 NCT07014462 Sep 2025 → Jun 2029 expected acute myeloid leukemia University of Vermont Enrolling by invitation No outcome recorded
Phase 1 NCT07182110 Aug 2025 → Aug 2026 overdue gallbladder disorder Makassed General Hospital Active not recruiting No outcome recorded
Phase 1 NCT06348108 Jul 2025 → Jul 2027 expected plasma cell myeloma Alfred Chung, MD Recruiting No outcome recorded
Phase 1 NCT06863259 May 2025 → Jan 2028 expected B-cell acute lymphoblastic leukemia Children's Hospital Medical Center, Cincinnati Recruiting No outcome recorded
Phase 1 NCT05773664 Nov 2024 glioblastoma City of Hope Medical Center Withdrawn No outcome recorded Stop: Business
Phase 1 NCT06433947 Aug 2024 → Jul 2026 overdue plasma cell myeloma Opna Bio LLC Recruiting No outcome recorded
Show all 118 trials opens the full record — a long page
Phase 1/2102 trials · 7 met primary · 1 missed
Phase 1/2 NCT07832110 Oct 2026 → Dec 2028 expected periodontitis The University of Texas Health Science Center at San Antonio Not yet recruiting No outcome recorded
Phase 1/2 NCT07601100 Sep 2026 → Jul 2029 expected plasma cell myeloma Dana-Farber Cancer Institute Not yet recruiting No outcome recorded
Phase 1/2 NCT06574048 Jul 2026 → Jul 2027 expected carbon monoxide-induced parkinsonism University of Nebraska Not yet recruiting No outcome recorded
Phase 1/2 NCT06930690 Jun → Dec 2026 expected — The Methodist Hospital Research Institute Recruiting No outcome recorded
Phase 1/2 NCT07479979 May 2026 → Jul 2027 expected plasma cell myeloma Natalie Callander Recruiting No outcome recorded
Phase 1/2 NCT07504822 Apr 2026 → Mar 2027 expected acne Yohanes Firmansyah, dr, MH, MM Not yet recruiting No outcome recorded
Phase 1/2 NCT07388069 Dec 2025 → Dec 2026 expected keratoconus TheiaNova Ltd. Enrolling by invitation No outcome recorded
Phase 1/2 NCT06892522 Jun 2025 → Feb 2036 expected plasma cell myeloma AbbVie Recruiting No outcome recorded
Phase 1/2 NCT06235567 Apr 2025 → Dec 2026 expected keratoconus Maanasa Indaram, MD Enrolling by invitation No outcome recorded
Phase 1/2 NCT07024043 Mar → Sep 2025 overdue — Ain Shams University Active not recruiting No outcome recorded
Phase 2632 trials · 23 met primary · 15 missed
Phase 2 NCT07605416 Apr 2027 → Nov 2032 expected plasma cell leukemia National Cancer Institute (NCI) Recruiting No outcome recorded
Phase 2 NCT07588698 Nov 2026 → Aug 2028 expected diffuse large B-cell lymphoma Carrie Ho, MD Not yet recruiting No outcome recorded
Phase 2 NCT07823192 Nov 2026 → Jan 2027 expected — KRL Hospital, Islamabad Not yet recruiting No outcome recorded
Phase 2 NCT07803562 Nov 2026 → Dec 2028 expected uveal melanoma University of California, San Diego Not yet recruiting No outcome recorded
Phase 2 NCT07839195 Oct 2026 → Jul 2028 expected arthritis, sacroiliac, arthropathy, chronic pain syndrome, neuritis Siriraj Hospital Enrolling by invitation No outcome recorded
Phase 2 NCT07763210 Sep 2026 → Mar 2028 expected diffuse large B-cell lymphoma, mantle cell lymphoma, marginal zone lymphoma Vanderbilt-Ingram Cancer Center Recruiting No outcome recorded
Phase 2 NCT07811986 Sep 2026 → Dec 2027 expected plasma cell myeloma Institute of Hematology & Blood Diseases Hospital, China Not yet recruiting No outcome recorded
Phase 2 NCT07698080 Jul 2026 → Jul 2028 expected aplastic anemia, leukemia, lymphoma, myelodysplastic syndrome +1 Hematology department of the 920th hospital Not yet recruiting No outcome recorded
Phase 2 NCT06818981 Jul 2026 obstructive sleep apnea syndrome Medical University of South Carolina Withdrawn No outcome recorded Stop: Business
Phase 2 NCT06348147 Jul 2026 → May 2027 disease related to hematopoietic stem cell transplant, plasma cell myeloma UNC Lineberger Comprehensive Cancer Center Withdrawn No outcome recorded
Show all 632 trials opens the full record — a long page
Phase 2/347 trials · 3 met primary · 3 missed
Phase 2/3 NCT07732712 Jan 2027 → Dec 2028 expected plasma cell myeloma The Affiliated People's Hospital of Ningbo University Not yet recruiting No outcome recorded
Phase 2/3 NCT07095452 Jan 2026 → Sep 2040 expected plasma cell myeloma AbbVie Recruiting No outcome recorded
Phase 2/3 NCT07853664 Jan → Dec 2026 expected — Thamar University Recruiting No outcome recorded
Phase 2/3 NCT07059156 Jun 2025 → Jun 2027 expected adult acute lymphoblastic leukemia Shanxi Bethune Hospital Recruiting No outcome recorded
Phase 2/3 NCT07343128 Jun → Dec 2025 fibromyalgia Sanliurfa Education and Research Hospital Completed No outcome recorded
Phase 2/3 NCT06212336 May 2025 → Jun 2027 expected Lassa fever Irrua Specialist Teaching Hospital Recruiting No outcome recorded
Phase 2/3 NCT06913374 May 2025 → May 2026 overdue primary thrombocytopenia Shandong University Not yet recruiting No outcome recorded
Phase 2/3 NCT06879379 Mar 2025 → Mar 2028 expected plasma cell myeloma Peking University People's Hospital Recruiting No outcome recorded
Phase 2/3 NCT07290595 Jan 2025 → Feb 2026 overdue hypotensive disorder Sahiwal medical college sahiwal Recruiting No outcome recorded
Phase 2/3 NCT06621329 Oct 2024 → Jul 2026 overdue headache disorder, subarachnoid hemorrhage University of California, Davis Recruiting No outcome recorded
Phase 3272 trials · 39 met primary · 28 missed
Phase 3 NCT07828054 Dec 2026 → Dec 2030 expected breast cancer, interstitial lung disease Mario Negri Institute for Pharmacological Research Not yet recruiting No outcome recorded
Phase 3 NCT07830108 Dec 2026 → Dec 2034 expected rheumatic fever, rheumatic heart disease Starship Child Health, Te Toka Tumai Auckland Not yet recruiting No outcome recorded
Phase 3 NCT07861776 Oct 2026 → Sep 2029 expected secondary hemophagocytic lymphohistiocytosis Post Graduate Institute of Medical Education and Research, Chandigarh Not yet recruiting No outcome recorded
Phase 3 NCT07543458 Oct 2026 → Jul 2030 expected arbovirus infection, dengue disease, hemorrhagic fever Oxford University Clinical Research Unit, Vietnam Not yet recruiting No outcome recorded
Phase 3 NCT07847047 Oct 2026 → Oct 2027 expected — Assiut University Not yet recruiting No outcome recorded
Phase 3 NCT07674576 Sep 2026 → Aug 2028 expected — CMC Ambroise Paré Not yet recruiting No outcome recorded
Phase 3 NCT07576660 Aug 2026 → Sep 2029 expected acute respiratory distress syndrome Southeast University, China Recruiting No outcome recorded
Phase 3 NCT07665762 Aug 2026 → Sep 2028 expected — The University of Hong Kong Recruiting No outcome recorded
Phase 3 NCT07413055 Mar → Nov 2026 expected — Oman Ministry of Health Recruiting No outcome recorded
Phase 3 NCT06511765 Mar → Sep 2026 overdue lumbar disk disease Elsan Recruiting No outcome recorded
Show all 272 trials opens the full record — a long page
Phase 4326 trials · 17 met primary · 23 missed
Phase 4 NCT07605065 Nov 2026 → Feb 2027 expected headache disorder Pak Emirates Military Hospital Not yet recruiting No outcome recorded
Phase 4 NCT07855341 Oct 2026 → Aug 2027 expected — Ain Shams University Not yet recruiting No outcome recorded
Phase 4 NCT07793760 Oct 2026 → Oct 2027 expected preeclampsia Assiut University Not yet recruiting No outcome recorded
Phase 4 NCT07795281 Sep → Dec 2026 expected — Gaziantep City Hospital Not yet recruiting No outcome recorded
Phase 4 NCT07699744 Aug 2026 → Jun 2027 expected rotator cuff syndrome Seoul National University Hospital Recruiting No outcome recorded
Phase 4 NCT07614802 Aug 2026 → Aug 2027 expected — Duke University Not yet recruiting No outcome recorded
Phase 4 NCT07064993 Jul 2026 → Feb 2027 expected — Arzu Esen Tekeli Not yet recruiting No outcome recorded
Phase 4 NCT07709884 Jul 2026 → Dec 2028 expected plasma cell myeloma The First Affiliated Hospital of Soochow University Not yet recruiting No outcome recorded
Phase 4 NCT07699315 Jul → Dec 2026 expected pulpitis Watim Medical & Dental College Not yet recruiting No outcome recorded
Phase 4 NCT07357597 Jun 2026 → Jan 2028 expected stomatitis AstraZeneca Recruiting No outcome recorded
Show all 326 trials opens the full record — a long page
Phase not applicable221 trials · 4 met primary · 8 missed
— NCT07435493 Nov 2026 expected adenoid hypertrophy, obstructive sleep apnea syndrome Ain Shams University Not yet recruiting No outcome recorded
— NCT07498998 Jul → Aug 2026 overdue carpal tunnel syndrome Tanta University Not yet recruiting No outcome recorded
— NCT07722091 Jul 2026 → Jan 2027 expected — Fujian Medical University Union Hospital Recruiting No outcome recorded
— NCT07677215 Jul 2026 → Sep 2027 expected osteoarthritis, knee Poznan University of Medical Sciences Not yet recruiting No outcome recorded
— NCT07631910 Jul → Oct 2026 expected — Sir Run Run Shaw Hospital Not yet recruiting No outcome recorded
— NCT07672873 Jun → Dec 2026 expected pulpitis Marmara University Recruiting No outcome recorded
— NCT07607691 Jun → Oct 2026 expected bursitis, chronic pain syndrome, frozen shoulder, rotator cuff syndrome Ankara City Hospital Bilkent Not yet recruiting No outcome recorded
— NCT07584200 Jun 2026 → Mar 2027 expected osteoarthritis, hip Poznan University of Medical Sciences Not yet recruiting No outcome recorded
— NCT07550803 Jun 2026 → Jun 2027 expected sleep disorder Seoul National University Hospital Not yet recruiting No outcome recorded
— NCT07341854 Jun 2026 → Jun 2027 expected neuropathy, painful Beijing Tiantan Hospital Not yet recruiting No outcome recorded
Show all 221 trials opens the full record — a long page
Phase not stated6 trials · 1 met primary
— NCT03969875 Aug 2018 → Apr 2022 osteoarthritis Icahn School of Medicine at Mount Sinai Completed No outcome recorded
— NCT02368301 — plasma cell myeloma Bristol-Myers Squibb No longer available No outcome recorded
— NCT04534322 — refractory plasma cell neoplasm Oncopeptides AB Approved for marketing No outcome recorded
— NCT02856438 — plasma cell myeloma Bristol-Myers Squibb No longer available No outcome recorded
— NCT01250808 — plasma cell myeloma Peking University Available No outcome recorded
— NCT00517894 — lymphoma Study Group of Medical Tumour Therapy (AGMT) No longer available Met primary
Comparator or background therapy1,891 trials
Phase 0 NCT07485127 Comparator Feb → Aug 2026 overdue — Sohag University Active not recruiting No outcome recorded
Phase 0 NCT05287035 Comparator Jul 2023 → Jan 2025 — University of Texas at Austin Unknown No outcome recorded
Phase 0 NCT05687981 Comparator Jan → Dec 2023 — Tanta University Unknown No outcome recorded
Phase 0 NCT05305404 Comparator Mar 2022 → Jun 2024 alcohol dependence Stony Brook University Completed No outcome recorded
Phase 0 NCT05142098 Comparator Jan → Jul 2022 — Dow University of Health Sciences Unknown No outcome recorded
Show all 1,891 trials opens the full record — a long page

Press releases naming this drug 139 releases

DateIssuerRelease
2026-10-08 Bristol-Myers Squibb Bristol Myers Squibb Announces ZENBEXUS (iberdomide) in Combination with Daratumumab and Dexamethasone (ZDd) Demonstrates Superior Progression-Free Survival vs. Standard of Care in Relapsed and Refractory Multiple Myeloma in Phase 3... bms.com ↗
2026-09-25 C4 Therapeutics, Inc. C4 Therapeutics Presents New Biomarker Data from the Cemsidomide Phase 1 Trial with Dexamethasone and Phase 1b Trial with Elranatamab (ELREXFIO®) in Relapsed/Refractory Multiple Myeloma at the 23rd International Myeloma Society (IMS) Annual Meeting c4therapeutics.com ↗
2026-09-03 C4 Therapeutics, Inc. C4 Therapeutics to Present New Biomarker Data on the Immunomodulatory Effects of Cemsidomide in Combination with Dexamethasone from its Phase 1 Relapsed/Refractory Multiple Myeloma Trial at the 23rd International Myeloma Society (IMS) Annual Meeting c4therapeutics.com ↗
2026-08-13 Bristol-Myers Squibb U.S. FDA Grants Accelerated Approval to Bristol Myers Squibb's First CELMoD Therapy ZENBEXUS™, in Combination with Daratumumab and Hyaluronidase-fihj and Dexamethasone (ZDd) for Patients with Multiple Myeloma, as Early as First Relapse bms.com ↗
2026-05-29 Oculis Oculis Announces Topline Results from DIAMOND Phase 3 Trials with OCS-01 in Diabetic Macular Edema oculis.com ↗
2026-04-20 Oculis Oculis Announces Completion of Last Patient Visit in Phase 3 DIAMOND Program with OCS-01 Eye Drops for the Treatment of Diabetic Macular Edema oculis.com ↗
2026-03-31 CellCentric Ltd. CellCentric Initiates DOMMINO-1, a Pivotal Phase 2 Clinical Trial of Inobrodib in Combination with Pomalidomide and Dexamethasone (InoPd) in Relapsed or Refractory Multiple Myeloma cellcentric.com ↗
2026-02-23 C4 Therapeutics, Inc. C4 Therapeutics Announces First Patient Dosed in Phase 2 MOMENTUM Trial of Cemsidomide, an Oral IKZF1/3 Degrader, in Combination with Dexamethasone for Relapsed/Refractory Multiple Myeloma c4therapeutics.com ↗
2024-09-10 Janssen Research & Development, LLC Dexamethasone reduces infusion-related reactions in patients with EGFR-mutated non-small cell lung cancer treated with intravenous RYBREVANT® (amivantamab-vmjw) jnj.com ↗
2024-09-10 Janssen Research & Development, LLC Dexamethasone reduces infusion-related reactions in patients with EGFR-mutated non-small cell lung cancer treated with intravenous RYBREVANT® (amivantamab-vmjw) jnj.com ↗
2024-05-11 Zydus Lifesciences Limited Zydus receives final approval from USFDA for Dexamethasone Tablets USP, 1 mg zyduslife.com ↗
2024-02-19 AffaMed Therapeutics Limited AffaMed Therapeutics Announces New Drug Application Acceptance by Singapore Health Sciences Authority (HSA) for DEXTENZA® for Treatment of Ocular Inflammation and Pain Following Ophthalmic Surgery, and Ocular Itching Associated with Allergic Conjunctivitis affamed.com ↗
Show all 139 releases opens the full record — a long page

Evidence & citations 97 cited values

Every value below carries the sentence it was read from. 3,672 sources stand behind the page.

FieldValueCited text
Known as Dexamethasone “including but not limited to DHAP (dexamethasone, cisplatin, high-dose cytarabine), ESHAP (etoposide, methylprednisolone, high-dose cytarabine and cisplatin), DICE...” NCT04486391 ↗
3546

“Standard Induction chemotherapy care included: vincristine, doxorubicin, and dexamethasone (VAD) (0.5 mg, 10 mg/m2, and 40 mg, respectively);dexamethasone,...” NCT00577096 ↗

“The study aims to evaluate the efficacy and safety of the quadruplet regimen Isatuximab in combination with Bortezomib, Lenalidomide, and Dexamethasone (Isa-VRD) compared to...” NCT07334535 ↗

“This is a randomized, controlled study to assess the safety and effectiveness of treatment with an intracanalicular dexamethasone (0.4mg) insert when utilized in conjunction...” NCT05665270 ↗

“Topical moxifloxacin 0.5% (Vigamox; Alcon Laboratories) four times per day, artificial tears (Systane Ultra; Alcon) every two hours, Dexamethasone 0.1% (Maxidex; Alcon...” NCT05331859 ↗

“Recommended rescue medications include tocilizumab for treatment of cytokine release syndrome (CRS); dexamethasone, acetaminophen, and diphenhydramine for CRS/infusion-related...” NCT07227597 ↗

“This is a randomized phase III trial of CC-5013 (lenalidomide, NSC-703813) and low dose dexamethasone (LLD) versus bortezomib (PS-341, NSC-681239), lenalidomide and low dose...” NCT01530594 ↗

“OZURDEX® (DEX implant, 0.7 mg) is a micro-ionized and non-preserved dexamethasone within a cylindrically-shaped 0.45 mm diameter x 6.5 mm length biodegradable Poly D,...” NCT03629210 ↗

“Patients randomized to receive corticosteroids will receive dexamethasone 20mg daily for 5 days and then 10mg for an additional 5 days, for a total of 10 days from the time of...” NCT05440851 ↗

“The medical intervention consists of intravenous dexamethasone (10 mg if bodyweight \< 70 kilograms, 20 mg if bodyweight \> 70 kilograms), intravenous cefazolin 2 grams,...” NCT04998513 ↗

“The purpose of this study is to find out what the response is and the side effects are with chemotherapy using a combination of drugs called D.T. PACE (Dexamethasone,...” NCT00107614 ↗

Show 3,536 more sources

Known as AR-1105 “PURPOSE: AR-1105 is a novel biodegradable sustained-release dexamethasone implant designed to deliver 6-month durability.” PMID 36542081 ↗ Oct 2022
Known as AR-1105-CF1 (dexamethasone intravitreal implant) “AR-1105-CF1 (dexamethasone intravitreal implant)” NCT03739593 ↗
Known as AR-1105-CF2 (dexamethasone intravitreal implant) “AR-1105-CF2 (dexamethasone intravitreal implant)” NCT03739593 ↗
Known as Corodex “The patients will receive Dexamethasone 8 mg (Corodex, Laboratorio Celsius, Montevideo, Uruguay) PO 1 hour before surgery (Almeida et al 2019)” NCT05924191 ↗
Known as Decadron “Anesthesia will be maintained with Sevoflurane, Magnesium, Lidocaine, Ketamine, Decadron, Ondansetron, and Ketorolac at a concentration range/dose(s) based on the clinical need...” NCT03367988 ↗
29

“Dexamethasone (Decadron®) will be given orally at a dose of 40 mg on days 1, 2, 3, 8, 15 and 22 during the first cycle and once a week on days 1, 8, 15, and 22 for each...” NCT00151203 ↗

“Dexamethasone (Decadron) caused minimal damage, while hydrocortisone (Solu-Cortef) and triamcinolone hexacetonide (Aristospan) caused widespread axonal and myelin degeneration.” PMID 7063571 ↗ Mar 1982

“QL block involves injection of 19 ml of 0.25% Bupivacaine and iml(4mg) of Decadron in a fascial place formed partly by the posterior surface of the quadratus lumborum muscle” NCT05480111 ↗

“The purpose of this study is to compare the safety and efficacy of XERECEPT® to dexamethasone (Decadron) a common treatment for symptoms of brain swelling (edema).” NCT00088166 ↗

“The medication used for the block are clonidine 100 mcg, Decadron PF 5mg and 0.25% bupivacaine 5 mL. This medication will be administered once during the block.” NCT04445337 ↗

“A Phase II Study of Dexamethasone (DECADRON®), Thalidomide (THALOMID®), and Lenalidomide (REVLIMID®) for Subjects With Relapsed or Refractory Multiple Myeloma” NCT00538824 ↗

“The names of the study drugs involved in this study are: * Teclistamab * Lenalidomide (also called Revlimid) * Dexamethasone (also called Decadron)” NCT05469893 ↗

“Steroids (such as Decadron or Dexamethasone) are medication used to reduce swelling around the tumour, and thus symptoms improve.” NCT00188864 ↗

“dexamethasone sodium phosphate (Decadron; 4 mg/mL; soluble). Again, this will be mixed with 1% lidocaine without epinephrine” NCT03641508 ↗

“Decadron will be given at a dose of 0.2 mg/kg intraoperatively, followed by Decadron 4 mg. every 6 hours for 24 hours.” NCT01065961 ↗

Show 19 more sources

Known as Decadron (dexamethasone) “Decadron (dexamethasone)” NCT00783367 ↗
Known as Decadron for Dexamethasone “Decadron for Dexamethasone” NCT01270932 ↗
Known as Decadron PF “The medication used for the block are clonidine 100 mcg, Decadron PF 5mg and 0.25% bupivacaine 5 mL. This medication will be administered once during the block.” NCT04445337 ↗
Known as Decort “The pulp chamber was irrigated with 2 mL of a dexamethasone sodium phosphate solution at a concentration of 4 mg/mL (Decort®, DEVA Holding, Türkiye).” NCT07233577 ↗
Known as DECTANCYL “B :dexamethasone (DECTANCYL)” NCT02552251 ↗
Known as dex “The non-inferiority of dexamethasone (DEX) on day 1, with or without low-dose DEX on days 2 and 3, combined with oral NEPA (netupitant/palonosetron), compared with the...” PMID 35999527 ↗ Aug 2022
47

“This study will investigate the efficacy and safety of OZURDEX® (dexamethasone intravitreal implants; DEX, Allergan, Inc. Irvine, CA) as monotherapy for the treatment of...” NCT05101928 ↗

“The aim of this study is to evaluate the effectiveness of submucosal 8 mg (2 mL) dexamethasone (DEX) on postoperative pain, swelling, chewing efficiency, trismus, healing, and...” PMID 39627624 ↗ Dec 2024

“D (Dexamethasone) group: (n=100) each patient received a placebo tablet identical to paracetamol tablet orally with sips of water and Dex 8 mg ampoule diluted in 100 ml 0.9% NS...” NCT03679065 ↗

“PHASE III STUDY OF HEPATIC ARTERY FLOXURIDINE (FUDR), LEUCOVORIN (LV), AND DEXAMETHASONE (DEX) VERSUS SYSTEMIC 5-FLUOROURACIL (5-FU) AND LEUCOVORIN (LV) AS TREATMENT FOR...” NCT00002716 ↗

“OBJECTIVE: To compare the efficacy of a single dose of oral dexamethasone (Dex) versus 5 days of twice-daily prednisolone (Pred) in the management of mild to moderate asthma...” PMID 17198210 ↗ Dec 2006

“The combination of dexamethasone (DEX), ondansetron (OND) and droperidol (DRO) is efficacious in preventing postoperative nausea and vomiting in adults, but has not been well...” PMID 28505233 ↗ Jun 2017

“Guidelines recommend the combination of a neurokinin-1 receptor antagonist (NK1RA), 5-hydroxytryptamine-3 RA (5-HT3RA), and dexamethasone (DEX) for CINV prophylaxis in...” PMID 28285236 ↗ Mar 2017

“Eligible patients were consecutively enrolled and sequentially assigned in an alternating 1:1 ratio to the dexamethasone (DEX) or control group according to the predefined...” NCT03079453 ↗

“We therefore conducted a phase I/II study to establish the safety and preliminary efficacy of IXA with pomalidomide (POM) and dexamethasone (DEX) in lenalidomide (LEN)/PI-refractory MM.” PMID 34559902 ↗ Oct 2021

“The study will test a new combination of 3 drugs: Isatuximab (Isa), Iberdomide (Iber) and Dexamethasone (Dex), in patients who have intermediate or high risk smouldering myeloma.” NCT06762769 ↗

Show 37 more sources

Known as DEX implant “Dexamethasone intravitreal implant (DEX implant; OZURDEX, Allergan, Inc., Irvine, CA)” NCT01581151 ↗
Known as DEX, dexamethasone “DEX, dexamethasone” NCT03629210 ↗
Known as DEX-I “Dexamethasone Intravitreal Implant (DEX-I, 0.7 mg)” NCT07438119 ↗
Known as DEXA “This paper describes the rationale and detailed protocol for a randomised controlled trial evaluating the efficacy of dexamethasone (DEXA) in reducing PES after PAE.” PMID 34725072 ↗ Nov 2021
2

“Patients receive dexamethasone (DEXA) on days 8-28.” NCT00613457 ↗

“Patients receive dexamethasone (DEXA) on days 8-28” NCT00430118 ↗

Known as DexaEDO “DexaEDO (dexamethasone) eyedrops without preservatives are applied additionally.” NCT01228149 ↗
Known as Dexametasone “Drug: Dexametasone” NCT07068048 ↗
3

NCT02036489 ↗

NCT01562977 ↗

NCT02238340 ↗

Known as Dexamethason “dexamethason (d 1, 2, 8, 9, 15, 16, 22, 23, 20mg, oral/intravenous injection)” NCT04612582 ↗
1

NCT00619086 ↗

Known as Dexamethasone (0.4mg) Insert “Dexamethasone (0.4mg) Insert” NCT05116345 ↗
Known as Dexamethasone (Caspian Tamin Pharmaceutical Co, Rasht, Iran) “Dexamethasone (Caspian Tamin Pharmaceutical Co, Rasht, Iran)” NCT03531970 ↗
Known as Dexamethasone (D) “Dexamethasone (D)” NCT01858922 ↗
Known as Dexamethasone (Decadron) “Dexamethasone (Decadron®)” NCT02128230 ↗
2

“Dexamethasone (Decadron)” NCT00250926 ↗

“Dexamethasone (Decadron)” NCT02724033 ↗

Known as Dexamethasone (Decadron, Baycadron) “Dexamethasone (Decadron, Baycadron)” NCT01297764 ↗
Known as Dexamethasone (perineural) “Dexamethasone (perineural)” NCT07584200 ↗