drugset / Trial / NCT04546126
Positron Emission Tomography (PET) Imaging of Cholesterol Trafficking: Clinical Evaluation of [18F]FNP-59 in Normal Human Subjects (Groups 2, 3 & 4)
Non-randomizedParallel-groupOpen-labelHealth-services research
Summary
This study will evaluate the feasibility of using a sub-therapeutic dose of a fluorine-18 analogue of NP-59 (\[18F\]FNP-59) to image the adrenal gland. Some participants are healthy normal subjects but have undergone interventions to manipulate hormones while other participants have known adrenal pathology.
Timeline
- Start
- 2021-11-01
- Primary completion
- 2026-12
- Completion
- 2026-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cosyntropin | Unknown | 250 ug | Intravenous |
| Subject | Dexamethasone | Small molecule | 1 mg | — |
| Subject | FNP-59 | Diagnostic / imaging agent | — | — |