drugset / Trial / NCT06879379

KPD Consolidation After ASCT in NDMM Patients

NCT06879379

Phase 2/3 Recruiting 202 enrolled Peking University People's Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

This study aims to evaluate the efficacy and safety of post-transplant consolidation therapy with the KPD regimen (carfilzomib, pomalidomide, and dexamethasone) versus no consolidation, followed by maintenance therapy, in patients with transplant-eligible newly diagnosed multiple myeloma (TE-NDMM). The primary goal is to compare minimal residual disease (MRD) negativity rates and overall treatment outcomes between the two groups.

Timeline

Start
2025-03
Primary completion
2028-03
Completion
2029-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Carfilzomib Other / unclassified
Subject Dexamethasone Small molecule
Subject Pomalidomide Other / unclassified

Indications