drugset / Trial / NCT02760043
Dexamethasone in Total Knee and Total Hip Arthroplasty
RandomizedParallel-groupTriple-blindSupportive care
Summary
This study will evaluate if the addition of dexamethasone to a local infiltration analgesia mixture will improve functional outcomes following total hip and knee arthroplasty.
Timeline
- Start
- 2016-04
- Primary completion
- 2018-10
- Completion
- 2018-10
Publications
- El-Boghdadly K, Short AJ, Gandhi R, Chan V. Addition of dexamethasone to local infiltration analgesia in elective total knee arthroplasty: double-blind, randomized control trial. Reg Anesth Pain Med. 2021 Feb;46(2):130-136. doi: 10.1136/rapm-2020-102079. Epub 2020 Nov 16.
- El-Boghdadly K, Short AJ, Gandhi R, Chan VWS. Addition of dexamethasone to local infiltration analgesia in elective total hip arthroplasty: a double-blind, randomized control trial. Reg Anesth Pain Med. 2019 Sep 27:rapm-2019-100873. doi: 10.1136/rapm-2019-100873. Online ahead of print.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexamethasone | Small molecule | 8 mg | — |
| Background | Epinephrine | Other / unclassified | 0.6 mg | — |
| Background | Ketorolac | Other / unclassified | 30 mg | — |
| Background | Ropivacaine | Other / unclassified | 2 % | — |