Ketorolac
Other / unclassified targets CDC42, PTGS2, RAC1 via inhibition
Regulatory milestones approvals, filings & regulatory actions · 2 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | EU (EMA) | Omidria | — | 2015-07-28 | europa.eu ↗ |
| Approved | US (FDA) | ACULAR LS | — | 2003-05-30 | fda.gov ↗ |
Trials 226 · started per year
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 014 trials | ||||||
| Phase 0 | NCT07064083 | Jul → Sep 2025 overdue | — | Al-Azhar University | Recruiting | No outcome recorded |
| Phase 0 | NCT06539637 | Sep 2023 → Nov 2025 overdue | cataract | DHS Consulting | Recruiting | No outcome recorded |
| Phase 0 | NCT05756504 | Feb 2023 → Jan 2024 | acute pancreatitis | Hayatabad Medical Complex | Unknown | No outcome recorded |
| Phase 0 | NCT05336266 | Jul 2022 → Feb 2025 overdue | pancreatic ductal adenocarcinoma | Andrew Hendifar, MD | Active not recruiting | No outcome recorded |
| Phase 0 | NCT05695664 | Aug 2021 → Jan 2022 | — | Benazir Bhutto Hospital, Rawalpindi | Completed | No outcome recorded |
| Phase 0 | NCT05019638 | Mar 2021 → May 2028 expected | — | University of Utah | Active not recruiting | No outcome recorded |
| Phase 0 | NCT03817034 | Mar 2021 | — | Massachusetts General Hospital | Withdrawn | No outcome recorded |
| Phase 0 | NCT04648540 | Dec 2020 → Aug 2022 | — | Cairo University | Completed | No outcome recorded |
| Phase 0 | NCT05037812 | Mar 2019 → Mar 2028 expected | — | University of Utah | Active not recruiting | No outcome recorded |
| Phase 0 | NCT03820193 | Jan 2019 → Jun 2020 | substance-related disorder | Henry Ford Health System | Completed | No outcome recorded |
| Phase 0 | NCT03665753 | Nov 2018 → Sep 2019 | — | Tehran University of Medical Sciences | Completed | No outcome recorded |
| Phase 0 | NCT03393364 | Apr 2018 → Jun 2020 | urinary system disorder | University Hospitals Cleveland Medical Center | Completed | No outcome recorded |
| Phase 0 | NCT06484439 | Feb 2018 → Nov 2021 | impacted teeth, multiple, neuropathy, painful | United States Naval Medical Center, San Diego | Completed | No outcome recorded |
| Phase 0 | NCT01670799 | Mar 2012 → Dec 2015 | fallopian tube cancer, ovarian cancer, peritoneum cancer | New Mexico Cancer Research Alliance | Completed | No outcome recorded |
| Phase 123 trials | ||||||
| Phase 1 | NCT05575999 | Jan → Oct 2026 expected | — | Kansas City Heart Rhythm Research Foundation | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT06911372 | Aug 2025 → Apr 2027 expected | gestational diabetes | Anna Stanhewicz, PhD | Recruiting | No outcome recorded |
| Phase 1 | NCT06653400 | Feb 2025 → Sep 2026 expected | pain agnosia, uterine anomalies | Icahn School of Medicine at Mount Sinai | Recruiting | No outcome recorded |
| Phase 1 | NCT06026553 | Aug 2022 → Dec 2023 | female infertility | Shady Grove Fertility Reproductive Science Center | Unknown | No outcome recorded |
| Phase 1 | NCT04941040 | Jul → Oct 2021 | supratentorial cancer | Kasr El Aini Hospital | Completed | No outcome recorded |
| Phase 1 | NCT03066115 | Dec 2020 → Dec 2021 | — | University of Wisconsin, Madison | Withdrawn | No outcome recorded |
| Phase 1 | NCT04505566 | Nov 2020 → Apr 2026 | diabetic retinopathy | Stephen J. Kim, MD | Completed | No outcome recorded |
| Phase 1 | NCT04353505 | Oct 2020 → Jun 2022 | cluster headache syndrome, migraine disorder, trigeminal neuralgia | Weill Medical College of Cornell University | Withdrawn | No outcome recorded |
| Phase 1 | NCT05054868 | Apr 2020 → Jul 2024 | synostosis | Medstar Health Research Institute | Unknown | No outcome recorded |
| Phase 1 | NCT03671746 | Feb 2019 → Jun 2023 | nervous system injury | Arun Aneja | Completed | No outcome recorded |
| Phase 1 | NCT03767036 | Jun 2017 | — | Grünenthal GmbH | Completed | No outcome recorded |
| Phase 1 | NCT02973958 | Feb 2017 → Jun 2018 | balanitis, neuropathy, painful, paraphimosis | Alberta Children's Hospital | Completed | No outcome recorded |
| Phase 1 | NCT02297906 | Feb 2015 → Nov 2017 | — | Columbia University | Terminated | No outcome recorded |
| Phase 1 | NCT01871077 | Sep → Dec 2013 | — | Laboratorios Sophia S.A de C.V. | Completed | No outcome recorded |
| Phase 1 | NCT02833207 | Apr 2012 → Nov 2021 | obesity disorder | University of Wisconsin, Madison | Terminated | No outcome recorded |
| Phase 1 | NCT01609881 | Mar 2012 → Oct 2016 | — | Vanderbilt University | Withdrawn | No outcome recorded |
| Phase 1 | NCT01164085 | Dec 2009 → Dec 2010 | — | Vanderbilt University | Completed | No outcome recorded |
| Phase 1 | NCT01365624 | Feb → Apr 2008 | — | American Regent, Inc. | Completed | No outcome recorded |
| Phase 1 | NCT01365650 | Dec 2007 → Feb 2008 | allergic rhinitis | Egalet Ltd | Completed | No outcome recorded |
| Phase 1 | NCT01363076 | Jun 2007 → Jan 2008 | — | Egalet Ltd | Completed | No outcome recorded |
| Phase 1 | NCT01363050 | Jan → Feb 2006 | — | Egalet Ltd | Completed | No outcome recorded |
| Phase 1 | NCT01355588 | Aug → Sep 2005 | — | Egalet Ltd | Completed | No outcome recorded |
| Phase 1 | NCT01356212 | Sep → Oct 2002 | — | Egalet Ltd | Completed | No outcome recorded |
| Phase 1/22 trials | ||||||
| Phase 1/2 | NCT06447194 | Oct 2025 → Jan 2027 | intervertebral disk degenerative disorder, lumbar spinal stenosis, spondylolisthesis | University of Maryland, Baltimore | Withdrawn | No outcome recorded |
| Phase 1/2 | NCT06158620 | Mar 2025 → Apr 2027 expected | ureterolithiasis, urolithiasis | University of Texas Southwestern Medical Center | Recruiting | No outcome recorded |
| Phase 224 trials | ||||||
| Phase 2 | NCT07487246 | Jun 2026 → Apr 2027 expected | — | Rush University Medical Center | Recruiting | No outcome recorded |
| Phase 2 | NCT06150898 | May 2025 → Apr 2027 expected | estrogen-receptor positive breast cancer | Jules Bordet Institute | Recruiting | No outcome recorded |
| Phase 2 | NCT06083571 | Jan 2024 → Dec 2025 | migraine disorder | Washington University School of Medicine | Terminated | No outcome recorded |
| Phase 2 | NCT05842044 | Sep 2023 → Sep 2026 expected | renal carcinoma | University of Miami | Recruiting | No outcome recorded |
| Phase 2 | NCT04646967 | Nov 2022 → Jan 2024 | balanitis, neuropathy, painful, paraphimosis | Alberta Children's Hospital | Completed | No outcome recorded |
| Phase 2 | NCT04291599 | Mar 2022 → Jul 2025 | acute pancreatitis | Boston Children's Hospital | Terminated | No outcome recorded |
| Phase 2 | NCT05324995 | Jan 2021 → Feb 2022 | — | Isfahan University of Medical Sciences | Completed | No outcome recorded |
| Phase 2 | NCT04495894 | Aug 2020 → Feb 2024 | non-small cell lung carcinoma, renal cell carcinoma | Emory University | Terminated | No outcome recorded |
| Phase 2 | NCT03978767 | Jun 2019 → Jun 2026 | severe pre-eclampsia | Washington University School of Medicine | Completed | No outcome recorded |
| Phase 2 | NCT03851172 | Mar → Dec 2019 | cataract | Assiut University | Unknown | No outcome recorded |
| Phase 2 | NCT03818919 | Jan 2019 → Dec 2020 | rotator cuff syndrome | Henry Ford Health System | Completed | No outcome recorded |
| Phase 2 | NCT03695367 | Oct → Nov 2018 | — | Heron Therapeutics | Completed | No outcome recorded |
| Phase 2 | NCT03111381 | Aug 2017 → Jun 2020 | nephrolithiasis | Yale University | Completed | No outcome recorded |
| Phase 2 | NCT03669081 | Sep 2016 → Sep 2018 | neuropathy, painful | University of Utah | Completed | No outcome recorded |
| Phase 2 | NCT02344225 | Jan 2015 → Jun 2018 | retinopathy of prematurity | State University of New York - Downstate Medical Center | Completed | No outcome recorded |
| Phase 2 | NCT01667120 | Jul 2012 → Dec 2018 | — | Nationwide Children's Hospital | Withdrawn | No outcome recorded |
| Phase 2 | NCT01498796 | Sep 2009 → May 2013 | acute tonsillitis | University of Alberta | Terminated | No outcome recorded |
| Phase 2 | NCT03693183 | Mar → Jun 2009 | dry eye syndrome | ORA, Inc. | Withdrawn | No outcome recorded |
| Phase 2 | NCT00621530 | Mar 2008 → Jun 2013 | — | Wake Forest University | Terminated | No outcome recorded |
| Phase 2 | NCT00693160 | Dec 2007 → Oct 2010 | — | Wake Forest University | Terminated | No outcome recorded |
| Phase 2 | NCT00349401 | Dec 2006 → ? | — | Wake Forest University Health Sciences | Withdrawn | No outcome recorded |
| Phase 2 | NCT00293631 | Nov 2005 → Mar 2006 | — | POZEN | Completed | No outcome recorded |
| Phase 2 | NCT01356225 | Feb → Mar 2004 | impacted teeth, multiple | Egalet Ltd | Completed | No outcome recorded |
| Phase 2 | NCT00001698 | Jun 1998 → Jun 2004 | leukoplakia, periodontal disorder | National Cancer Institute (NCI) | Completed | No outcome recorded |
| Phase 2/38 trials | ||||||
| Phase 2/3 | NCT06519955 | Oct 2024 → May 2026 overdue | developmental dysplasia of the hip | Michael C Willey | Recruiting | No outcome recorded |
| Phase 2/3 | NCT04939987 | Aug → Oct 2022 | — | Wake Forest University Health Sciences | Withdrawn | No outcome recorded |
| Phase 2/3 | NCT03825809 | Jan 2019 → Jan 2020 overdue | substance-related disorder | Henry Ford Health System | Recruiting | No outcome recorded |
| Phase 2/3 | NCT03818932 | Jan 2019 → Jan 2020 | — | Henry Ford Health System | Completed | No outcome recorded |
| Phase 2/3 | NCT04441112 | May 2018 → Aug 2019 | osteoarthritis, hip, osteoarthritis, knee | Saint Alphonsus Regional Medical Center | Completed | No outcome recorded |
| Phase 2/3 | NCT01799863 | Jun 2012 → Mar 2013 | viral conjunctivitis | Fundação Altino Ventura | Completed | No outcome recorded |
| Phase 2/3 | NCT00617097 | Jan 2008 → May 2009 | — | Johns Hopkins University | Completed | No outcome recorded |
| Phase 2/3 | NCT00576329 | Nov 2006 → Oct 2007 | — | Emory University | Completed | No outcome recorded |
| Phase 337 trials | ||||||
| Phase 3 | NCT06994442 | Dec 2025 → Jul 2029 expected | acute respiratory failure | Weill Medical College of Cornell University | Recruiting | No outcome recorded |
| Phase 3 | NCT07305883 | Dec 2025 → Jun 2026 overdue | — | Tehran University of Medical Sciences | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT06968806 | Oct 2025 → Sep 2027 expected | aortic disorder | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | Recruiting | No outcome recorded |
| Phase 3 | NCT06819956 | Jun 2025 → Dec 2026 expected | — | University of Alberta | Recruiting | No outcome recorded |
| Phase 3 | NCT05992883 | Jul 2023 → Dec 2026 expected | osteoarthritis, hand | Mayo Clinic | Recruiting | No outcome recorded |
| Phase 3 | NCT05102591 | Feb 2022 → Mar 2024 | migraine disorder | University of Calgary | Completed | No outcome recorded |
| Phase 3 | NCT04528563 | May 2021 → Feb 2023 | appendicitis | Hamilton Health Sciences Corporation | Completed | No outcome recorded |
| Phase 3 | NCT04429022 | Nov 2020 → May 2022 | — | State University of New York at Buffalo | Completed | No outcome recorded |
| Phase 3 | NCT04133623 | Nov 2019 → Sep 2021 | — | IRCCS Burlo Garofolo | Completed | No outcome recorded |
| Phase 3 | NCT03678675 | May 2019 → Jan 2022 | pregnancy disorder | Tufts Medical Center | Completed | No outcome recorded |
| Phase 3 | NCT04246554 | May 2019 → Oct 2020 | — | University Hospitals Cleveland Medical Center | Completed | No outcome recorded |
| Phase 3 | NCT04246541 | Apr 2019 → Sep 2021 | musculoskeletal system disorder, substance-related disorder | University Hospitals Cleveland Medical Center | Completed | No outcome recorded |
| Phase 3 | NCT03823534 | Feb 2019 → Dec 2026 expected | bone neoplasm, plasma cell myeloma, substance-related disorder | St. Louis University | Recruiting | No outcome recorded |
| Phase 3 | NCT03967847 | Feb 2019 → Oct 2020 | rotator cuff syndrome | University Hospitals Cleveland Medical Center | Completed | No outcome recorded |
| Phase 3 | NCT03616340 | Aug 2018 → Aug 2019 | osteoarthritis, knee, rotator cuff syndrome, shoulder impingement syndrome | OSF Healthcare System | Unknown | No outcome recorded |
| Phase 3 | NCT03584373 | Jul 2018 → Mar 2022 | nephrolithiasis | Montefiore Medical Center | Completed | No outcome recorded |
| Phase 3 | NCT03586934 | Jun 2018 → Jun 2019 | substance-related disorder | Rush University Medical Center | Withdrawn | No outcome recorded |
| Phase 3 | NCT03485625 | Mar 2018 → Apr 2019 | — | Assiut University | Completed | No outcome recorded |
| Phase 3 | NCT04322968 | Jan 2018 → Jun 2019 | chronic pain syndrome, post-traumatic stress disorder | VA Ann Arbor Healthcare System | Completed | No outcome recorded |
| Phase 3 | NCT02358681 | Jun 2015 → Mar 2021 | migraine disorder | Columbia University | Completed | No outcome recorded |
| Phase 3 | NCT02465255 | Mar 2015 → Jun 2017 | — | IRCCS Burlo Garofolo | Completed | No outcome recorded |
| Phase 3 | NCT02141139 | Sep 2014 → Jan 2016 | breast neoplasm | Samsung Medical Center | Unknown | No outcome recorded |
| Phase 3 | NCT02540070 | Aug 2014 → Dec 2017 | osteoarthritis, knee | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | Unknown | No outcome recorded |
| Phase 3 | NCT02568995 | May 2014 → Sep 2016 | — | Örebro University, Sweden | Completed | No outcome recorded |
| Phase 3 | NCT02361645 | Mar → Nov 2014 | hyalitis | University of Brescia | Completed | No outcome recorded |
| Phase 3 | NCT02102516 | Mar 2014 → Jun 2015 | — | Egalet Ltd | Completed | No outcome recorded |
| Phase 3 | NCT02093689 | Feb → Aug 2014 | intraoperative floppy iris syndrome | Omeros Corporation | Terminated | No outcome recorded |
| Phase 3 | NCT01806259 | Feb 2013 → Oct 2015 | female breast carcinoma | Catholic University of Louvain | Completed | No outcome recorded |
| Phase 3 | NCT02266433 | Aug 2012 → Jul 2018 | de Quervain disease, epicondylitis, tenosynovitis | NYU Langone Health | Terminated | No outcome recorded |
| Phase 3 | NCT01579565 | Apr → Nov 2012 | — | Omeros Corporation | Completed | No outcome recorded |
| Phase 3 | NCT01761071 | Jan → Nov 2012 | — | Yonsei University | Completed | No outcome recorded |
| Phase 3 | NCT01258309 | Dec 2010 → Jan 2011 | conjunctivitis, seasonal allergic rhinitis | Allergan | Completed | No outcome recorded |
| Phase 3 | NCT00524264 | Oct 2007 → Apr 2008 | cataract | Allergan | Completed | No outcome recorded |
| Phase 3 | NCT00521456 | Oct 2007 → Mar 2008 | cataract | Allergan | Completed | No outcome recorded |
| Phase 3 | NCT00405262 | May 2006 → Oct 2008 | — | The Hospital for Sick Children | Completed | No outcome recorded |
| Phase 3 | NCT00266786 | Dec 2005 → Feb 2007 | — | Egalet Ltd | Completed | No outcome recorded |
| Phase 3 | NCT01260883 | May 2000 → Mar 2008 | — | Seattle Children's Hospital | Completed | No outcome recorded |
| Phase 489 trials | ||||||
| Phase 4 | NCT07368738 | Apr 2026 → Apr 2027 expected | — | Horizon Health Network | Enrolling by invitation | No outcome recorded |
| Phase 4 | NCT07185724 | Nov 2025 → Oct 2027 expected | female infertility | Jessica D. Kresowik | Recruiting | No outcome recorded |
| Phase 4 | NCT06860711 | Jul 2025 → Jun 2028 expected | chronic kidney disease | University of Colorado, Denver | Recruiting | No outcome recorded |
| Phase 4 | NCT06201676 | Feb 2025 → Dec 2026 expected | opioid abuse | Massachusetts General Hospital | Recruiting | No outcome recorded |
| Phase 4 | NCT07006168 | Nov 2024 → Dec 2026 expected | — | The University of Hong Kong | Recruiting | No outcome recorded |
| Phase 4 | NCT04895280 | Nov 2024 → Nov 2026 | rotator cuff syndrome, tendinitis | Michael Khazzam | Withdrawn | No outcome recorded |
| Phase 4 | NCT06579703 | Sep 2024 → Jul 2027 expected | sickle cell disease, vascular occlusion disorder | Children's Blood and Cancer Center at Dell Children's Medical Center | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT06498440 | Sep 2024 → Jul 2025 overdue | ocular hypertension, open-angle glaucoma | St. Joseph's Healthcare Hamilton | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT06189781 | Dec 2023 → Dec 2026 expected | cerebral palsy, developmental dysplasia of the hip | University of California, Los Angeles | Recruiting | No outcome recorded |
| Phase 4 | NCT06113497 | Nov 2023 → Oct 2024 | — | Kyunghee University Medical Center | Unknown | No outcome recorded |
| Phase 4 | NCT05664074 | Nov 2022 → Feb 2025 | acute pancreatitis | David Vitale MD | Completed | No outcome recorded |
| Phase 4 | NCT05336968 | Sep 2022 → Nov 2025 | osteoarthritis, knee | United Health Services Hospitals, Inc. | Unknown | No outcome recorded |
| Phase 4 | NCT05248984 | Jun 2022 → Nov 2023 | — | Ohio State University | Completed | No outcome recorded |
| Phase 4 | NCT05190341 | Mar 2022 → Oct 2024 | female infertility | Madigan Army Medical Center | Terminated | No outcome recorded |
| Phase 4 | NCT05074056 | Feb 2022 → Dec 2024 | disorder of pharynx, obstructive sleep apnea syndrome | St. Louis University | Completed | No outcome recorded |
| Phase 4 | NCT04829799 | Feb 2022 → Aug 2023 | — | University of Florida | Withdrawn | No outcome recorded |
| Phase 4 | NCT04141319 | Dec 2021 → Jul 2022 | supratentorial cancer | Beijing Tiantan Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT05383820 | Sep 2021 → Mar 2022 | malposition of teeth with or without hypodontia/oligodontia | University of Guadalajara | Unknown | No outcome recorded |
| Phase 4 | NCT04771156 | Sep 2021 → Mar 2027 expected | cleft lip/palate | The University of Texas Health Science Center, Houston | Recruiting | No outcome recorded |
| Phase 4 | NCT04990804 | Aug 2021 → Feb 2022 | spinal cord disorder, substance-related disorder | Vanderbilt University Medical Center | Terminated | No outcome recorded |
| Phase 4 | NCT04761302 | Apr 2021 → Oct 2022 | — | University of Puerto Rico | Completed | No outcome recorded |
| Phase 4 | NCT04040452 | Mar 2021 → Jun 2026 overdue | congenital heart disease | Phoenix Children's Hospital | Recruiting | No outcome recorded |
| Phase 4 | NCT03805607 | Jan 2021 → Feb 2022 | blood coagulation disease, poisoning | Beth Israel Deaconess Medical Center | Completed | No outcome recorded |
| Phase 4 | NCT05361824 | Jan → Jun 2021 | coronary artery disorder | National Institute of Cardiovascular Diseases, Pakistan | Completed | No outcome recorded |
| Phase 4 | NCT04380298 | Dec 2020 → Jul 2021 | supratentorial cancer | Beijing Tiantan Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT04528173 | Jul 2020 → Aug 2023 | sleep disorder, substance-related disorder, tonsillitis | Children's Hospital of Philadelphia | Terminated | No outcome recorded |
| Phase 4 | NCT03535116 | Jan 2020 → Dec 2024 | — | Dr. Chandran Medical Prof Corp | Unknown | No outcome recorded |
| Phase 4 | NCT04130464 | Sep 2019 → Sep 2026 expected | — | Ying Liu | Recruiting | No outcome recorded |
| Phase 4 | NCT03987022 | Aug 2019 → Apr 2022 | — | MetroHealth Medical Center | Completed | No outcome recorded |
| Phase 4 | NCT03861611 | Jul 2019 → Feb 2021 | — | Montefiore Medical Center | Completed | No outcome recorded |
| Phase 4 | NCT03864133 | Jul 2019 → Jun 2021 | cataract | Wake Forest University Health Sciences | Completed | No outcome recorded |
| Phase 4 | NCT03693404 | Dec 2018 → Jun 2021 | — | NYU Langone Health | Completed | No outcome recorded |
| Phase 4 | NCT03738904 | Oct 2018 → Aug 2022 | anus disorder | Cedars-Sinai Medical Center | Completed | No outcome recorded |
| Phase 4 | NCT03467750 | Jul 2018 → Aug 2023 | obstructive sleep apnea syndrome | Emory University | Completed | No outcome recorded |
| Phase 4 | NCT03694821 | Jul 2018 → Jul 2019 | osteoarthritis | UConn Health | Terminated | No outcome recorded |
| Phase 4 | NCT03453541 | Nov 2017 → Nov 2022 | — | Albany Medical College | Terminated | No outcome recorded |
| Phase 4 | NCT03888144 | Oct 2017 → Aug 2021 | nephrolithiasis, ureterolithiasis | The Cleveland Clinic | Completed | No outcome recorded |
| Phase 4 | NCT03278691 | Oct 2017 → Dec 2023 | — | Henry Ford Health System | Unknown | No outcome recorded |
| Phase 4 | NCT03472872 | Sep 2017 → Jun 2020 | headache disorder | Corewell Health South | Withdrawn | No outcome recorded |
| Phase 4 | NCT03028012 | May 2017 → May 2019 | myofascial pain syndrome | University of Utah | Terminated | No outcome recorded |
| Phase 4 | NCT04115644 | May → Sep 2017 | rotator cuff syndrome | Michael Khazzam | Terminated | No outcome recorded |
| Phase 4 | NCT03105674 | May → Nov 2017 | anal fistula, hemorrhoid, ulcer of anus and rectum | Columbia University | Withdrawn | No outcome recorded |
| Phase 4 | NCT02958566 | Jan → Dec 2017 | colon carcinoma, constipation disorder, diverticulitis of colon, paralytic ileus +1 | University of Illinois College of Medicine at Peoria | Unknown | No outcome recorded |
| Phase 4 | NCT02829944 | Nov 2016 → Mar 2019 | — | Duke University | Completed | No outcome recorded |
| Phase 4 | NCT02885441 | Sep 2016 → Feb 2019 | acute pancreatitis | Ilam University of Medical Sciences | Terminated | No outcome recorded |
| Phase 4 | NCT03727048 | Aug 2016 → Mar 2018 | — | Rothman Institute Orthopaedics | Completed | No outcome recorded |
| Phase 4 | NCT02509312 | May 2016 → Oct 2017 | blood coagulation disease, poisoning, substance-related disorder | University Hospitals Cleveland Medical Center | Completed | No outcome recorded |
| Phase 4 | NCT02867176 | Jan → Jul 2016 | — | Instituto de Oftalmología Fundación Conde de Valenciana | Completed | No outcome recorded |
| Phase 4 | NCT02612272 | Nov 2015 → Oct 2017 | osteoarthritis, knee | St. Luke's Hospital, Pennsylvania | Unknown | No outcome recorded |
| Phase 4 | NCT02604537 | Oct 2015 → Oct 2024 | de Quervain disease | OrthoCarolina Research Institute, Inc. | Completed | No outcome recorded |
| Phase 4 | NCT02571283 | Oct 2015 → May 2016 | — | University of Louisville | Withdrawn | No outcome recorded |
| Phase 4 | NCT02570503 | Oct 2015 → Feb 2021 | osteoarthritis, knee | Virginia Commonwealth University | Terminated | No outcome recorded |
| Phase 4 | NCT02474654 | Jul 2015 → Jan 2019 | — | Health Sciences North Research Institute | Completed | No outcome recorded |
| Phase 4 | NCT02653742 | May 2015 → Dec 2022 | neuropathy, painful, otitis media | Anica Crnkovic | Unknown | No outcome recorded |
| Phase 4 | NCT02380898 | Mar → Sep 2015 | — | Assiut University | Completed | No outcome recorded |
| Phase 4 | NCT02729285 | Jul → Oct 2014 | — | Sun Yat-sen University | Completed | No outcome recorded |
| Phase 4 | NCT03031795 | Jul 2014 → Mar 2016 | — | OhioHealth | Completed | No outcome recorded |
| Phase 4 | NCT02078492 | Mar 2014 → Dec 2015 | — | Antonios Likourezos | Completed | No outcome recorded |
| Phase 4 | NCT01807234 | Feb 2013 → Dec 2014 | migraine disorder | Johns Hopkins University | Completed | No outcome recorded |
| Phase 4 | NCT02060604 | Dec 2012 → Jan 2014 | wet macular degeneration | University of Brescia | Completed | No outcome recorded |
| Phase 4 | NCT01898052 | Oct 2012 → Feb 2014 | — | Thammasat University | Completed | No outcome recorded |
| Phase 4 | NCT01736358 | Oct 2012 → Jun 2014 | urolithiasis | Montefiore Medical Center | Terminated | No outcome recorded |
| Phase 4 | NCT01374828 | Jan 2012 → Dec 2013 | — | The Cleveland Clinic | Withdrawn | No outcome recorded |
| Phase 4 | NCT01534806 | Jan 2012 | migraine disorder | Akron Children's Hospital | Withdrawn | No outcome recorded |
| Phase 4 | NCT01514175 | Jan → Dec 2012 | chronic pain syndrome | Culpeper Surgery Center | Unknown | No outcome recorded |
| Phase 4 | NCT01490931 | Nov 2011 → Aug 2012 | — | Hersh, Elliot V., DMD, MS, PhD | Completed | No outcome recorded |
| Phase 4 | NCT01291472 | Jun → Sep 2011 | — | Universitaire Ziekenhuizen KU Leuven | Completed | No outcome recorded |
| Phase 4 | NCT01304212 | Apr 2011 → Feb 2014 | — | Jose Antonio Bernia Gil | Completed | No outcome recorded |
| Phase 4 | NCT01859585 | Mar 2011 → Jan 2013 | — | Prince of Songkla University | Completed | No outcome recorded |
| Phase 4 | NCT01560767 | Oct 2010 → Jul 2011 | osteoarthritis, knee | University of Warwick | Completed | No outcome recorded |
| Phase 4 | NCT01345162 | Mar 2010 → May 2012 | — | Fondazione IRCCS Policlinico San Matteo di Pavia | Completed | No outcome recorded |
| Phase 4 | NCT01281891 | Sep 2009 → Sep 2012 | osteoarthritis, hip | Region Örebro County | Unknown | No outcome recorded |
| Phase 4 | NCT00981435 | Sep 2009 → Sep 2015 | glaucoma | Stanford University | Completed | No outcome recorded |
| Phase 4 | NCT00865540 | Mar 2009 → Aug 2011 | cataract | Clinica Oftamologica Zona Sul | Unknown | No outcome recorded |
| Phase 4 | NCT01832311 | Jan 2009 → Dec 2011 | cataract, type 2 diabetes mellitus | University of Zagreb | Completed | No outcome recorded |
| Phase 4 | NCT00765128 | Oct 2008 → Nov 2010 | nephrolithiasis | Mayo Clinic | Completed | No outcome recorded |
| Phase 4 | NCT00765232 | Oct 2008 → Nov 2010 | — | Mayo Clinic | Completed | No outcome recorded |
| Phase 4 | NCT00774540 | Aug 2008 → Sep 2014 | — | Oslo University Hospital | Completed | No outcome recorded |
| Phase 4 | NCT00901628 | Apr 2008 → Mar 2009 | osteoarthritis, knee | Seoul National University Hospital | Completed | No outcome recorded |
| Phase 4 | NCT00562627 | Nov 2007 → Jun 2009 | osteoarthritis, knee | Asker & Baerum Hospital | Completed | No outcome recorded |
| Phase 4 | NCT00366691 | Feb 2006 → Sep 2007 | cataract | Medical University of South Carolina | Completed | No outcome recorded |
| Phase 4 | NCT00347204 | Jan → Jun 2006 | hyperopia, myopia | Center For Excellence In Eye Care | Completed | No outcome recorded |
| Phase 4 | NCT00289419 | Feb 2005 → Feb 2006 | osteoarthritis, hip | University of Aarhus | Completed | No outcome recorded |
| Phase 4 | NCT00161577 | Jan 2004 → Jun 2006 | — | Weill Medical College of Cornell University | Completed | No outcome recorded |
| Phase 4 | NCT00348244 | — | cataract | Innovative Medical | Completed | No outcome recorded |
| Phase 4 | NCT00348582 | — | cataract | Innovative Medical | Completed | No outcome recorded |
| Phase 4 | NCT00433225 | — | macular retinal edema | Innovative Medical | Completed | No outcome recorded |
| Phase 4 | NCT00347503 | — | cataract | Innovative Medical | Completed | No outcome recorded |
| Phase 4 | NCT00377546 | — | — | Innovative Medical | Completed | No outcome recorded |
| Phase not applicable29 trials | ||||||
| — | NCT07141589 | Aug 2024 → Nov 2025 overdue | — | Cairo University | Recruiting | No outcome recorded |
| — | NCT06112548 | Mar 2024 → Nov 2025 | osteoarthritis, knee | Damascus University | Completed | No outcome recorded |
| — | NCT06307106 | Jan → Oct 2024 | — | Zagazig University | Completed | No outcome recorded |
| — | NCT06608056 | Jan → Jun 2024 | — | Pakistan Air Force (PAF) Hospital Islamabad | Completed | No outcome recorded |
| — | NCT05908851 | Nov 2023 → Nov 2024 | — | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | Unknown | No outcome recorded |
| — | NCT05489796 | Jun → Aug 2022 | — | Seoul National University Bundang Hospital | Completed | No outcome recorded |
| — | NCT05206110 | Apr 2022 → Sep 2024 | — | Jessa Hospital | Completed | No outcome recorded |
| — | NCT06630520 | Mar → Jun 2022 | — | Taipei Veterans General Hospital, Taiwan | Completed | No outcome recorded |
| — | NCT05189704 | Dec 2021 → Feb 2023 | — | Seoul National University Hospital | Unknown | No outcome recorded |
| — | NCT05994287 | Jan 2021 → Jan 2022 | — | Federal State Budgetary Organization, Federal Center for Traumatology, Orthopedics and Arthroplasty | Completed | No outcome recorded |
| — | NCT04483427 | Sep 2020 → Jul 2022 | obstructive sleep apnea syndrome | Bahaa Mohammed Refaie | Unknown | No outcome recorded |
| — | NCT05393414 | Nov 2019 → Mar 2020 | — | University of Puerto Rico | Completed | No outcome recorded |
| — | NCT04176783 | Mar 2018 → Jul 2021 | — | OrthoCarolina Research Institute, Inc. | Completed | No outcome recorded |
| — | NCT05248724 | Aug 2017 → Sep 2020 | — | Castilla-La Mancha Health Service | Completed | No outcome recorded |
| — | NCT02700451 | Mar 2016 → Dec 2021 | lumbar disk disease, osteoarthritis, spine, spinal stenosis, spondylosis | Hospital for Special Surgery, New York | Completed | No outcome recorded |
| — | NCT03116672 | Feb 2016 → Feb 2017 | pulpitis | Universidad Autonoma de Baja California | Completed | No outcome recorded |
| — | NCT02470299 | Oct 2015 → Oct 2018 | fallopian tube cancer, ovarian cancer, peritoneum cancer | New Mexico Cancer Research Alliance | Completed | No outcome recorded |
| — | NCT02937896 | Jan 2015 → Feb 2016 | — | Shahid Beheshti University of Medical Sciences | Completed | No outcome recorded |
| — | NCT03402100 | Oct 2014 → Dec 2019 | drug pseudoallergy, myopia | Chang Gung Memorial Hospital | Unknown | No outcome recorded |
| — | NCT01836406 | Dec 2012 → Jun 2013 | renal cell carcinoma | Yonsei University | Completed | No outcome recorded |
| — | NCT01664559 | Jul 2012 → Mar 2014 | — | Lynn Ngo | Completed | No outcome recorded |
| — | NCT01576276 | Apr 2012 → Feb 2017 | — | Massachusetts General Hospital | Completed | No outcome recorded |
| — | NCT01471639 | Nov 2011 → Jun 2012 | — | The Cleveland Clinic | Completed | No outcome recorded |
| — | NCT01595282 | Jun 2011 → Jun 2012 | — | Planned Parenthood League of Massachusetts | Completed | No outcome recorded |
| — | NCT01133639 | May 2010 → Feb 2012 | toe, misshapen | Beth Israel Deaconess Medical Center | Terminated | No outcome recorded |
| — | NCT01081535 | May 2009 → Feb 2010 | — | Yonsei University | Completed | No outcome recorded |
| — | NCT00956462 | Jul 2007 → Dec 2009 | glaucoma | University Health Network, Toronto | Unknown | No outcome recorded |
| — | NCT01513564 | Jan 2001 → Dec 2003 | spondylolisthesis | Northern Orthopaedic Division, Denmark | Completed | No outcome recorded |
| — | NCT01449448 | Sep 2000 → Sep 2005 | bursitis, shoulder impingement syndrome | Madigan Army Medical Center | Withdrawn | No outcome recorded |
Also used as a comparator or background therapy in 221 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 03 trials | ||||||
| Phase 0 | NCT06081101 Comparator | Jan 2025 → Jun 2026 overdue | arthritis, sacroiliac | McMaster University | Not yet recruiting | No outcome recorded |
| Phase 0 | NCT06462573 Background | Sep 2024 → Sep 2026 expected | ureterolithiasis | Assiut University | Not yet recruiting | No outcome recorded |
| Phase 0 | NCT03638999 Comparator | Jul 2018 → Oct 2026 expected | urolithiasis | Washington University School of Medicine | Recruiting | No outcome recorded |
| Phase 13 trials | ||||||
| Phase 1 | NCT05062356 Background | Nov 2021 → Aug 2024 | chronic pain syndrome | St. Mary's Research Center, Canada | Completed | No outcome recorded |
| Phase 1 | NCT02400645 Comparator | Mar 2015 → May 2016 | — | University of Tennessee | Terminated | No outcome recorded |
| Phase 1 | NCT00548678 Comparator | Oct → Nov 2007 | — | Javelin Pharmaceuticals | Completed | No outcome recorded |
| Phase 1/23 trials | ||||||
| Phase 1/2 | NCT06729047 Comparator | Dec 2024 → Nov 2025 overdue | intracranial hypotension | Assiut University | Not yet recruiting | No outcome recorded |
| Phase 1/2 | NCT06681688 Comparator | Jul 2024 → Jun 2025 overdue | cataract | Inder Paul Singh, M.D. | Recruiting | No outcome recorded |
| Phase 1/2 | NCT03066544 Comparator | Nov 2016 → Dec 2019 | migraine disorder | Hartford HealthCare | Unknown | No outcome recorded |
| Phase 222 trials | ||||||
| Phase 2 | NCT06853327 Comparator | May 2025 → Jun 2026 overdue | — | University of North Carolina, Chapel Hill | Enrolling by invitation | No outcome recorded |
| Phase 2 | NCT06087237 Comparator | Oct 2023 → Jun 2024 | female breast carcinoma | Mansoura University | Completed | No outcome recorded |
| Phase 2 | NCT06039423 Comparator | Jul → Aug 2023 | — | Alexandria University | Completed | No outcome recorded |
| Phase 2 | NCT06267820 Comparator | Jun → Dec 2023 | — | Sohag University | Completed | No outcome recorded |
| Phase 2 | NCT05180214 Comparator | Jan → Aug 2021 | nodular goiter | Sohag University | Completed | No outcome recorded |
| Phase 2 | NCT03913702 Comparator | Sep 2019 → Nov 2022 | shoulder impingement syndrome | The University of Texas Medical Branch, Galveston | Terminated | No outcome recorded |
| Phase 2 | NCT03968146 Background | Jun → Nov 2019 | idiopathic scoliosis | Kasr El Aini Hospital | Completed | No outcome recorded |
| Phase 2 | NCT03885596 Background | Mar → Jul 2019 | — | Concentric Analgesics | Completed | No outcome recorded |
| Phase 2 | NCT03426137 Comparator | Sep 2018 → Mar 2019 | substance-related disorder | University of Maryland, Baltimore | Terminated | No outcome recorded |
| Phase 2 | NCT03599089 Comparator | Jul → Oct 2018 | post-surgical hypoinsulinemia | Concentric Analgesics | Completed | No outcome recorded |
| Phase 2 | NCT04112160 Comparator | Jun 2018 → Jun 2019 | urolithiasis | University of Texas Southwestern Medical Center | Completed | No outcome recorded |
| Phase 2 | NCT03448068 Background | Apr 2018 → Jan 2020 | — | Mayo Clinic | Completed | No outcome recorded |
| Phase 2 | NCT03410212 Comparator | Feb → Jul 2018 | pulpitis | Azad University of Medical Sciences | Completed | No outcome recorded |
| Phase 2 | NCT02956616 Background | Sep 2017 → Jun 2018 | — | Montefiore Medical Center | Completed | No outcome recorded |
| Phase 2 | NCT03551808 Comparator | Jan → Jun 2017 | cystoid macular edema | Shahid Beheshti University of Medical Sciences | Unknown | No outcome recorded |
| Phase 2 | NCT02614118 Comparator | Sep 2015 → May 2016 | pulpitis | Azad University of Medical Sciences | Completed | No outcome recorded |
| Phase 2 | NCT02860949 Background | Apr 2014 → Apr 2015 | osteoarthritis, knee | Thammasat University | Completed | No outcome recorded |
| Phase 2 | NCT03331315 Comparator | Sep 2013 → Jun 2016 | — | Michael Ulm, MD | Completed | No outcome recorded |
| Phase 2 | NCT01673191 Comparator | Nov 2012 → Dec 2014 | diabetes mellitus, macular retinal edema | Retinal Consultants of Arizona | Completed | No outcome recorded |
| Phase 2 | NCT01571791 Comparator | Jun 2012 → Dec 2021 | heart valve disorder | Mansoura University | Suspended | No outcome recorded |
| Phase 2 | NCT00900887 Comparator | Apr 2008 → Mar 2015 | diabetic retinopathy, macular retinal edema | Hospital Juarez de Mexico | Completed | No outcome recorded |
| Phase 2 | NCT01242644 Comparator | Oct 2006 → Oct 2009 | — | University of South Alabama | Completed | No outcome recorded |
| Phase 2/315 trials | ||||||
| Phase 2/3 | NCT07151417 Background | Sep 2025 → Aug 2026 overdue | osteoarthritis, knee | Walter Reed National Military Medical Center | Not yet recruiting | No outcome recorded |
| Phase 2/3 | NCT07047040 Comparator | Aug 2025 → Oct 2027 expected | neuropathy, painful, osteoarthritis, knee | Assiut University | Not yet recruiting | No outcome recorded |
| Phase 2/3 | NCT05597878 Comparator | Apr 2023 → Feb 2026 | prostate cancer, substance-related disorder | Wake Forest University Health Sciences | Terminated | No outcome recorded |
| Phase 2/3 | NCT05194904 Comparator | Jan 2022 → Jul 2023 | — | Assiut University | Unknown | No outcome recorded |
| Phase 2/3 | NCT05607641 Comparator | Jul 2021 → May 2022 | — | Darnitsa Pharmaceutical Company | Completed | No outcome recorded |
| Phase 2/3 | NCT04441762 Comparator | Dec 2020 → Feb 2022 | — | Oman Medical Speciality Board | Completed | No outcome recorded |
| Phase 2/3 | NCT03367988 Background | Dec 2018 → Jan 2023 | drug dependence | University of South Florida | Unknown | No outcome recorded |
| Phase 2/3 | NCT03836781 Comparator | Apr 2018 → Jun 2019 | chronic periodontitis | Amirhossein Farahmand | Completed | No outcome recorded |
| Phase 2/3 | NCT04119921 Comparator | Jan → Jun 2018 | diabetic macular edema | Shahid Beheshti University of Medical Sciences | Completed | No outcome recorded |
| Phase 2/3 | NCT03178539 Comparator | Jan 2017 → Dec 2018 | — | Assiut University | Completed | No outcome recorded |
| Phase 2/3 | NCT02760043 Background | Apr 2016 → Oct 2018 | osteoarthritis | University Health Network, Toronto | Unknown | No outcome recorded |
| Phase 2/3 | NCT02617199 Comparator | Nov 2015 → Dec 2016 | acute pancreatitis | Hospital General Naval de Alta Especialidad - Escuela Medico Naval | Unknown | No outcome recorded |
| Phase 2/3 | NCT02449954 Comparator | Jun 2014 → Apr 2015 | breast cancer | Assiut University | Unknown | No outcome recorded |
| Phase 2/3 | NCT01604785 Comparator | Nov 2012 → Aug 2016 | migraine disorder | Oregon Health and Science University | Completed | No outcome recorded |
| Phase 2/3 | NCT01769352 Comparator | Aug 2012 → Apr 2016 | cystoid macular edema | Johns Hopkins University | Completed | No outcome recorded |
| Phase 321 trials | ||||||
| Phase 3 | NCT07299630 Background | Dec 2025 → May 2026 | — | Ain Shams University | Completed | No outcome recorded |
| Phase 3 | NCT07092566 Comparator | Nov 2025 → Oct 2027 expected | renal carcinoma | Wake Forest University Health Sciences | Recruiting | No outcome recorded |
| Phase 3 | NCT06973785 Comparator | Jul 2025 → Jun 2026 overdue | — | The Cleveland Clinic | Active not recruiting | No outcome recorded |
| Phase 3 | NCT07257874 Comparator | Jul → Dec 2025 | — | Islamabad Medical and Dental College | Completed | No outcome recorded |
| Phase 3 | NCT07183436 Comparator | Nov 2023 → Jul 2025 | frozen shoulder | Mahidol University | Completed | No outcome recorded |
| Phase 3 | NCT05291598 Comparator | May 2022 → May 2023 | — | University of Miami | Completed | No outcome recorded |
| Phase 3 | NCT04650893 Comparator | Jan 2021 → Dec 2023 | voice disorders | University of Nebraska | Terminated | No outcome recorded |
| Phase 3 | NCT04618497 Comparator | Oct → Nov 2020 | — | Hospital Authority, Hong Kong | Completed | No outcome recorded |
| Phase 3 | NCT03825198 Comparator | Aug 2019 → Dec 2023 | neuropathy, painful, peripheral nerve lesion | Dr M. B. Breebaart | Unknown | No outcome recorded |
| Phase 3 | NCT04872283 Comparator | May 2019 → Dec 2021 | — | Rothman Institute Orthopaedics | Unknown | No outcome recorded |
| Phase 3 | NCT03330119 Background | Oct 2017 → Jun 2018 | pregnancy disorder, substance-related disorder | Brest, Norman A., M.D. | Terminated | No outcome recorded |
| Phase 3 | NCT03025594 Comparator | Jan → Aug 2017 | osteoarthritis, knee | maximiliano barahona vasquez | Unknown | No outcome recorded |
| Phase 3 | NCT03081416 Comparator | May → Sep 2016 | headache disorder | Brooke Army Medical Center | Completed | No outcome recorded |
| Phase 3 | NCT04482192 Comparator | Jun 2015 → Jan 2020 | — | Zagazig University | Completed | No outcome recorded |
| Phase 3 | NCT01789216 Comparator | Jul 2013 → Dec 2018 | — | Major Extremity Trauma Research Consortium | Completed | No outcome recorded |
| Phase 3 | NCT01782781 Comparator | Nov 2012 → Oct 2014 | — | Göteborg University | Completed | No outcome recorded |
| Phase 3 | NCT00507026 Comparator | Jul 2007 → Oct 2008 | — | Pfizer | Completed | No outcome recorded |
| Phase 3 | NCT00448110 Comparator | May 2006 → Nov 2007 | neuropathy, painful | Javelin Pharmaceuticals | Completed | No outcome recorded |
| Phase 3 | NCT00332774 Comparator | Feb → Dec 2006 | cataract | Alcon Research | Completed | No outcome recorded |
| Phase 3 | NCT00405730 Comparator | Nov 2005 → Jul 2006 | cataract | Alcon Research | Completed | No outcome recorded |
| Phase 3 | NCT00707421 Comparator | Jul 2005 → May 2009 | glaucoma | Universitaire Ziekenhuizen KU Leuven | Completed | No outcome recorded |
| Phase 488 trials | ||||||
| Phase 4 | NCT07430085 Comparator | Jul 2026 → Jan 2028 expected | osteoarthritis, knee | Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07276802 Comparator | Apr → Dec 2026 expected | cataract | Research Insight LLC | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT06513208 Comparator | Jan 2026 → Jun 2027 expected | — | University of Maryland St. Joseph Medical Center | Recruiting | No outcome recorded |
| Phase 4 | NCT07276906 Comparator | Jan → Jun 2026 overdue | — | University of South Alabama | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT06958549 Comparator | Dec 2025 → Dec 2026 expected | — | Assiut University | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07158476 Comparator | Oct 2025 → Sep 2030 expected | — | St. Louis University | Recruiting | No outcome recorded |
| Phase 4 | NCT07102641 Comparator | Aug 2025 → Aug 2027 expected | — | Thomas Jefferson University | Recruiting | No outcome recorded |
| Phase 4 | NCT06750627 Comparator | Jan → Mar 2025 overdue | — | Udayana University | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT06484192 Comparator | Jun 2024 → Jun 2025 | — | Rothman Institute Orthopaedics | Unknown | No outcome recorded |
| Phase 4 | NCT05875571 Comparator | Feb 2024 → May 2025 overdue | uterine inflammatory disease | Arkansas Children's Hospital Research Institute | Recruiting | No outcome recorded |
| Phase 4 | NCT06202664 Comparator | Jan → Aug 2024 | — | Muhammad Haroon Anwar | Completed | No outcome recorded |
| Phase 4 | NCT05776953 Comparator | Dec 2023 → Sep 2026 expected | urinary tract obstruction | Hackensack Meridian Health | Recruiting | No outcome recorded |
| Phase 4 | NCT07037888 Comparator | Dec 2023 → Sep 2026 expected | — | Henry Ford Health System | Recruiting | No outcome recorded |
| Phase 4 | NCT02465138 Comparator | Nov 2023 → Dec 2025 | pancreatitis | University of California, San Francisco | Withdrawn | No outcome recorded |
| Phase 4 | NCT05924165 Comparator | May 2023 → Jan 2025 | nephrolithiasis | Icahn School of Medicine at Mount Sinai | Completed | No outcome recorded |
| Phase 4 | NCT05292339 Comparator | Jan 2023 → Jul 2027 expected | disease of the tendon, osteoarthritis | Emory University | Recruiting | No outcome recorded |
| Phase 4 | NCT05488847 Background | Jun 2022 → Dec 2024 overdue | arthropathy | Henry Ford Health System | Active not recruiting | No outcome recorded |
| Phase 4 | NCT05239767 Comparator | Jun 2022 → Apr 2023 | musculoskeletal system disorder | Montefiore Medical Center | Completed | No outcome recorded |
| Phase 4 | NCT05157113 Comparator | May 2022 → Jun 2026 overdue | cataract | University of California, San Francisco | Recruiting | No outcome recorded |
| Phase 4 | NCT05523102 Comparator | Mar → Jul 2022 | neuropathy, painful | Indonesia University | Completed | No outcome recorded |
| Phase 4 | NCT05188053 Comparator | Mar 2022 → Apr 2024 | — | Mayo Clinic | Completed | No outcome recorded |
| Phase 4 | NCT04704297 Comparator | Dec 2020 → Jul 2022 overdue | myofascial pain syndrome | Madigan Army Medical Center | Recruiting | No outcome recorded |
| Phase 4 | NCT04763876 Comparator | Jun → Nov 2020 | musculoskeletal system disorder, pain agnosia | William Beaumont Army Medical Center | Completed | No outcome recorded |
| Phase 4 | NCT04282200 Comparator | Feb 2020 → Dec 2021 | acute pancreatitis | University of Cincinnati | Unknown | No outcome recorded |
| Phase 4 | NCT04316936 Background | Dec 2019 → Dec 2020 | cataract | Silverstein Eye Centers | Completed | No outcome recorded |
| Phase 4 | NCT04074265 Comparator | Dec 2019 → Mar 2023 | cerebral palsy, developmental dysplasia of the hip | University of California, Los Angeles | Completed | No outcome recorded |
| Phase 4 | NCT03534895 Background | May 2019 → May 2020 | neuropathy, painful | University of Porto | Unknown | No outcome recorded |
| Phase 4 | NCT04651556 Comparator | Apr 2019 → Jun 2020 | — | Menoufia University | Completed | No outcome recorded |
| Phase 4 | NCT03619785 Comparator | Nov 2018 → Aug 2019 | myopathy, congenital, with respiratory insufficiency and bone fractures | Andrew A Herring | Unknown | No outcome recorded |
| Phase 4 | NCT03319784 Comparator | Sep 2018 → Sep 2020 | diabetes mellitus, rotator cuff syndrome, tendinitis | Milton S. Hershey Medical Center | Withdrawn | No outcome recorded |
| Phase 4 | NCT03649334 Background | Aug → Oct 2018 | hematopoietic and lymphoid cell neoplasm | Mansoura University | Completed | No outcome recorded |
| Phase 4 | NCT03464461 Comparator | May 2018 → May 2024 | — | University of Missouri-Columbia | Terminated | No outcome recorded |
| Phase 4 | NCT03472469 Comparator | Apr 2018 → Jul 2019 | — | The University of Texas Health Science Center, Houston | Completed | No outcome recorded |
| Phase 4 | NCT03137498 Comparator | Mar 2017 → Mar 2019 | urinary tract obstruction | The Brooklyn Hospital Center | Unknown | No outcome recorded |
| Phase 4 | NCT02987920 Background | Jan 2017 → Jan 2018 | — | University of Southern California | Terminated | No outcome recorded |
| Phase 4 | NCT03032458 Comparator | Jan → Oct 2017 | urolithiasis | Mansoura University | Completed | No outcome recorded |
| Phase 4 | NCT02953210 Background | Nov 2016 | neuropathy, painful, paralytic ileus | Federal University of São Paulo | Unknown | No outcome recorded |
| Phase 4 | NCT02922985 Comparator | Oct 2016 → Jun 2017 | — | The University of Texas Medical Branch, Galveston | Completed | No outcome recorded |
| Phase 4 | NCT02895035 Comparator | Sep 2016 → Dec 2018 | cataract | Milton S. Hershey Medical Center | Terminated | No outcome recorded |
| Phase 4 | NCT02769325 Background | May 2016 → May 2017 | — | Clinica Santa Maria | Unknown | No outcome recorded |
| Phase 4 | NCT02782273 Comparator | May → Sep 2016 | urinary tract obstruction | Loredana Ghinea | Unknown | No outcome recorded |
| Phase 4 | NCT02782286 Comparator | May → Sep 2016 | — | Loredana Ghinea | Unknown | No outcome recorded |
| Phase 4 | NCT03119038 Comparator | Apr 2016 → Oct 2022 | osteoarthritis | Rush University Medical Center | Withdrawn | No outcome recorded |
| Phase 4 | NCT03221569 Comparator | Feb 2016 → Feb 2020 | migraine disorder | The Brooklyn Hospital Center | Unknown | No outcome recorded |
| Phase 4 | NCT02765815 Comparator | Feb 2016 → Jan 2017 | osteoarthritis, knee | Holy Cross Hospital, Florida | Withdrawn | No outcome recorded |
| Phase 4 | NCT02543801 Comparator | Jan 2016 → Aug 2018 | — | Kootenai Health | Completed | No outcome recorded |
| Phase 4 | NCT03143244 Comparator | Jan → Nov 2016 | — | Mansoura University | Completed | No outcome recorded |
| Phase 4 | NCT02664116 Comparator | Jan 2016 → Jul 2017 | migraine disorder | Scripps Health | Unknown | No outcome recorded |
| Phase 4 | NCT02374008 Background | Mar → Nov 2015 | — | Regionshospitalet Silkeborg | Completed | No outcome recorded |
| Phase 4 | NCT02327923 Comparator | Jan 2015 → Feb 2016 | gallstones | B.P. Koirala Institute of Health Sciences | Completed | No outcome recorded |
| Phase 4 | NCT02242201 Comparator | Sep 2014 → Sep 2016 | — | Mayo Clinic | Completed | No outcome recorded |
| Phase 4 | NCT02608788 Comparator | Sep 2014 → Jul 2015 | pharyngitis | Chang Gung Memorial Hospital | Completed | No outcome recorded |
| Phase 4 | NCT02646072 Comparator | Aug 2014 → May 2015 | cystoid macular edema, diabetes mellitus | University of Malaya | Completed | No outcome recorded |
| Phase 4 | NCT02808728 Background | May 2014 → Mar 2015 | osteoarthritis | DeClaire LaMacchia Orthopaedic Institute | Unknown | No outcome recorded |
| Phase 4 | NCT02162121 Background | May 2014 → Oct 2016 | — | ASST Gaetano Pini-CTO | Completed | No outcome recorded |
| Phase 4 | NCT02128646 Background | Apr 2014 → Jan 2017 | — | University of Kansas Medical Center | Completed | No outcome recorded |
| Phase 4 | NCT02082067 Background | Mar 2014 → Sep 2015 | — | ASST Gaetano Pini-CTO | Withdrawn | No outcome recorded |
| Phase 4 | NCT03017430 Background | Jan 2014 → Dec 2019 | substance withdrawal syndrome | St. Petersburg Bekhterev Research Psychoneurological Institute | Completed | No outcome recorded |
| Phase 4 | NCT02682498 Comparator | Oct 2013 → Jul 2015 | osteoarthritis, knee | University of California, Irvine | Completed | No outcome recorded |
| Phase 4 | NCT02084576 Comparator | Aug 2013 | cataract, cystoid macular edema | Hospital Oftalmologico de Brasilia | Completed | No outcome recorded |
| Phase 4 | NCT01901393 Comparator | Jul 2013 → Aug 2014 | — | Cumberland Pharmaceuticals | Completed | No outcome recorded |
| Phase 4 | NCT01868425 Comparator | Apr 2013 → Dec 2017 | — | University of Wisconsin, Madison | Completed | No outcome recorded |
| Phase 4 | NCT01543165 Background | Dec 2012 → Dec 2013 | urinary tract obstruction | Seoul National University Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT01667445 Background | Sep 2012 → Sep 2014 | osteoarthritis | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | Completed | No outcome recorded |
| Phase 4 | NCT01650519 Comparator | Sep → Dec 2012 | — | Cumberland Pharmaceuticals | Completed | No outcome recorded |
| Phase 4 | NCT01507246 Background | Dec 2011 → Jul 2012 | intestinal obstruction | Pacira Pharmaceuticals, Inc | Completed | No outcome recorded |
| Phase 4 | NCT02058290 Background | Dec 2011 → Sep 2012 | intestinal obstruction | Pacira Pharmaceuticals, Inc | Terminated | No outcome recorded |
| Phase 4 | NCT01449708 Comparator | Nov 2011 → Oct 2012 | — | Coastal Anesthesiology Consultants | Completed | No outcome recorded |
| Phase 4 | NCT01267864 Comparator | Nov 2010 → Mar 2013 | migraine disorder | Montefiore Medical Center | Completed | No outcome recorded |
| Phase 4 | NCT01163214 Comparator | Jul 2010 → Jun 2013 | — | Mark J. Spangehl, M.D. | Completed | No outcome recorded |
| Phase 4 | NCT01112436 Comparator | May 2010 → Apr 2012 | — | Chung-Ang University Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT01344395 Comparator | Mar 2010 → Jun 2011 | — | University of Aarhus | Completed | No outcome recorded |
| Phase 4 | NCT01395069 Comparator | Feb 2010 → May 2011 | macular retinal edema | Queen's University | Completed | No outcome recorded |
| Phase 4 | NCT02508857 Comparator | Jan 2010 → Jan 2014 | — | Cancer Institute of the State of São Paulo | Completed | No outcome recorded |
| Phase 4 | NCT01011673 Comparator | Nov 2009 → Sep 2012 | headache disorder | Montefiore Medical Center | Completed | No outcome recorded |
| Phase 4 | NCT00868348 Comparator | May 2009 → Jun 2011 | — | University of Aarhus | Completed | No outcome recorded |
| Phase 4 | NCT00869219 Comparator | Mar → Aug 2009 | — | Santa Casa de Misericordia de Santos | Unknown | No outcome recorded |
| Phase 4 | NCT00869037 Comparator | Mar 2009 → Jul 2011 | — | University of Manitoba | Unknown | No outcome recorded |
| Phase 4 | NCT00785863 Comparator | Dec 2008 → Apr 2009 | — | Ullevaal University Hospital | Completed | No outcome recorded |
| Phase 4 | NCT00791323 Comparator | Nov 2008 → Aug 2009 | — | Allergan | Completed | No outcome recorded |
| Phase 4 | NCT00904904 Comparator | Apr 2008 → Jun 2009 | cataract | Bausch & Lomb Incorporated | Completed | No outcome recorded |
| Phase 4 | NCT00560443 Comparator | Feb 2008 → Apr 2012 | — | IRCCS Burlo Garofolo | Completed | No outcome recorded |
| Phase 4 | NCT00603083 Comparator | Jan → Oct 2008 | neuropathy, painful | Vejle Hospital | Completed | No outcome recorded |
| Phase 4 | NCT00595543 Comparator | Jan 2008 → Mar 2009 | cystoid macular edema | Bp Consulting, Inc | Completed | No outcome recorded |
| Phase 4 | NCT00520260 Comparator | Aug 2007 → Aug 2008 | asthenopia, dry eye syndrome | Florida Eye Microsurgical Institute | Completed | No outcome recorded |
| Phase 4 | NCT00638508 Comparator | Jun 2007 → Aug 2008 | — | Maimonides Medical Center | Completed | No outcome recorded |
| Phase 4 | NCT00421967 Comparator | Jan 2007 → Mar 2008 | osteoarthritis, knee | University of Aarhus | Terminated | No outcome recorded |
| Phase 4 | NCT00115336 Comparator | Jan 2005 → Aug 2008 | sickle cell disease | Children's Hospital Medical Center, Cincinnati | Terminated | No outcome recorded |
| Phase not applicable66 trials | ||||||
| — | NCT07658521 Background | Jul → Dec 2026 expected | — | Ain Shams University | Enrolling by invitation | No outcome recorded |
| — | NCT07352059 Comparator | Jan → Feb 2026 overdue | — | SYED HAIDER ALI | Not yet recruiting | No outcome recorded |
| — | NCT07244757 Comparator | Dec 2025 → Apr 2026 | — | Cairo University | Completed | No outcome recorded |
| — | NCT07268911 Comparator | Nov 2025 → May 2026 overdue | — | South Valley University | Recruiting | No outcome recorded |
| — | NCT07032883 Background | Jun 2025 → Feb 2026 overdue | female breast carcinoma | Cairo University | Not yet recruiting | No outcome recorded |
| — | NCT06570577 Background | Feb 2025 → Mar 2027 expected | neuropathy, painful | Stony Brook University | Recruiting | No outcome recorded |
| — | NCT06502067 Background | Jul 2024 → Jun 2025 overdue | breast cancer | Ain Shams University | Not yet recruiting | No outcome recorded |
| — | NCT07500454 Comparator | Jun → Jul 2024 | — | ISSSTE Hospital Regional "Gral. Ignacio Zaragoza" | Completed | No outcome recorded |
| — | NCT05282251 Comparator | May → Jul 2024 | lung disorder | Assiut University | Unknown | No outcome recorded |
| — | NCT06326983 Background | May 2024 → Jan 2026 | delirium, tonsillitis | Boston Children's Hospital | Completed | No outcome recorded |
| — | NCT06243575 Background | Feb → Mar 2024 | neuropathy, painful | Department of Medical Services Ministry of Public Health of Thailand | Unknown | No outcome recorded |
| — | NCT05983354 Comparator | Jan → Jun 2024 | migraine disorder | Health Sciences North Research Institute | Unknown | No outcome recorded |
| — | NCT07337135 Background | Oct 2023 → Apr 2024 | morbid obesity | Hospital dos Lusíadas | Completed | No outcome recorded |
| — | NCT05975294 Comparator | Aug 2023 → Aug 2024 | — | Sohag University | Unknown | No outcome recorded |
| — | NCT06182098 Background | Jun 2023 → Jun 2025 | migraine disorder | Dayton Children's Hospital | Unknown | No outcome recorded |
| — | NCT06167187 Comparator | Jun 2023 → Apr 2024 | — | Ain Shams University | Unknown | No outcome recorded |
| — | NCT05782608 Comparator | Apr → Nov 2023 | colorectal cancer | Cairo University | Completed | No outcome recorded |
| — | NCT05801900 Comparator | Apr → Jun 2023 | — | Cairo University | Unknown | No outcome recorded |
| — | NCT05861791 Comparator | Feb 2023 → Jul 2024 | — | Chung-Ang University Gwangmyeong Hospital | Completed | No outcome recorded |
| — | NCT05610384 Comparator | Nov 2022 → May 2023 | — | Cairo University | Completed | No outcome recorded |
| — | NCT05543785 Comparator | Nov 2022 → May 2027 expected | — | Mansoura University | Recruiting | No outcome recorded |
| — | NCT05234619 Comparator | Jan → Jun 2022 | — | Sohag University | Unknown | No outcome recorded |
| — | NCT05474040 Comparator | Dec 2021 → Dec 2022 | — | Zagazig University | Completed | No outcome recorded |
| — | NCT05132595 Comparator | Nov 2021 → Jul 2022 | subjective cognitive decline | Tianjin Medical University General Hospital | Unknown | No outcome recorded |
| — | NCT05097768 Comparator | Aug 2021 → Jan 2022 | pulpitis | Alfarabi Colleges | Completed | No outcome recorded |
| — | NCT04302129 Comparator | Jan → Apr 2020 | — | Mohamed Elsayed | Unknown | No outcome recorded |
| — | NCT03742180 Comparator | Jan 2018 → Apr 2019 | — | Mansoura University | Withdrawn | No outcome recorded |
| — | NCT04238377 Comparator | Dec 2017 → Mar 2020 | breast cancer | National Cancer Institute, Egypt | Unknown | No outcome recorded |
| — | NCT03323684 Background | Oct 2017 → Mar 2018 | gallbladder disorder | Mansoura University | Completed | No outcome recorded |
| — | NCT03171610 Comparator | Jun 2017 → Jan 2018 | — | Yonsei University | Completed | No outcome recorded |
| — | NCT03106818 Comparator | Jul 2016 → Mar 2017 | — | Assiut University | Completed | No outcome recorded |
| — | NCT02752646 Comparator | Apr 2016 → Mar 2017 | cataract | MDbackline, LLC | Completed | No outcome recorded |
| — | NCT03996564 Comparator | Feb → Dec 2016 | — | San Antonio Military Medical Center | Completed | No outcome recorded |
| — | NCT02691572 Background | Feb → May 2016 | — | Mansoura University | Completed | No outcome recorded |
| — | NCT02681211 Comparator | Feb 2016 → Nov 2024 | migraine disorder | University of Louisville | Unknown | No outcome recorded |
| — | NCT02647047 Background | Jan → Nov 2016 | hepatobiliary neoplasm, liver disorder, secondary malignant neoplasm | Ospedale San Raffaele | Unknown | No outcome recorded |
| — | NCT03041948 Background | Sep 2015 → Sep 2018 | — | Alberta Children's Hospital | Unknown | No outcome recorded |
| — | NCT03041935 Background | Sep 2015 → Jan 2019 | cryptorchidism | Alberta Children's Hospital | Completed | No outcome recorded |
| — | NCT02563587 Comparator | Sep 2015 → Jan 2016 | — | Hospital General Naval de Alta Especialidad - Escuela Medico Naval | Unknown | No outcome recorded |
| — | NCT02502877 Background | Jul 2015 → Mar 2016 | — | Hospital da Luz, Portugal | Completed | No outcome recorded |
| — | NCT03580980 Comparator | Apr 2015 → Nov 2017 | childhood malignant neoplasm, neuropathy, painful | National Cancer Institute, Egypt | Completed | No outcome recorded |
| — | NCT02276495 Background | Jan 2015 → Jun 2020 | — | University of California, Irvine | Completed | No outcome recorded |
| — | NCT02476799 Background | Nov 2014 → May 2015 | female reproductive system disorder | Ewha Womans University Mokdong Hospital | Completed | No outcome recorded |
| — | NCT02219087 Comparator | Aug 2014 → Mar 2016 | osteoarthritis, knee | OhioHealth | Completed | No outcome recorded |
| — | NCT02881996 Background | Jun 2014 → Jun 2016 | appendicitis | Children's Mercy Hospital Kansas City | Completed | No outcome recorded |
| — | NCT02112448 Comparator | Jun 2014 → May 2016 | congenital heart disease | Wake Forest University Health Sciences | Completed | No outcome recorded |
| — | NCT02312739 Background | Feb 2014 → Mar 2015 | — | University of New Mexico | Completed | No outcome recorded |
| — | NCT02039427 Comparator | Jan 2014 → Oct 2015 | tracheal disorder | Yeungnam University College of Medicine | Completed | No outcome recorded |
| — | NCT02012244 Background | Jan → Dec 2014 | colorectal cancer | Severance Hospital | Completed | No outcome recorded |
| — | NCT01993238 Background | Nov 2013 → Jan 2014 | — | Solta Medical | Completed | No outcome recorded |
| — | NCT02299349 Comparator | Aug → Dec 2013 | — | TriHealth Inc. | Completed | No outcome recorded |
| — | NCT02169856 Background | Jul 2013 → Feb 2014 | — | Benazir Bhutto Hospital, Rawalpindi | Completed | No outcome recorded |
| — | NCT01734954 Background | Apr → Aug 2013 | — | CES University | Unknown | No outcome recorded |
| — | NCT02162134 Background | Jan 2013 → Feb 2014 | ileus | Benazir Bhutto Hospital, Rawalpindi | Completed | No outcome recorded |
| — | NCT01566838 Comparator | Oct 2012 → Dec 2015 | — | Inova Health Care Services | Completed | No outcome recorded |
| — | NCT02181426 Comparator | Mar 2012 → Dec 2016 | — | Medical University of South Carolina | Completed | No outcome recorded |
| — | NCT01305733 Comparator | Mar 2011 → May 2012 | — | Coxa, Hospital for Joint Replacement | Unknown | No outcome recorded |
| — | NCT00974753 Comparator | Mar 2010 → Mar 2012 | macular retinal edema | Queen's University | Completed | No outcome recorded |
| — | NCT01103401 Comparator | Oct 2009 → Jan 2010 | cataract | Veroia General Hospital | Completed | No outcome recorded |
| — | NCT00992082 Comparator | Aug 2009 → May 2011 | osteoarthritis | Region Örebro County | Unknown | No outcome recorded |
| — | NCT00992355 Comparator | Jan → Mar 2009 | cataract | Veroia General Hospital | Completed | No outcome recorded |
| — | NCT00478036 Comparator | May 2007 → Jan 2014 | open-angle glaucoma | University of Colorado, Denver | Terminated | No outcome recorded |
| — | NCT00799175 Comparator | Apr 2007 → Jun 2008 | — | Region Örebro County | Completed | No outcome recorded |
| — | NCT00485108 Comparator | Jan 2007 → Jun 2009 | exfoliation syndrome, open-angle glaucoma | Queen's University | Completed | No outcome recorded |
| — | NCT00653926 Comparator | Sep 2005 → Mar 2007 | — | Region Örebro County | Completed | No outcome recorded |
| — | NCT00845754 Comparator | Sep 1999 → Aug 2001 | — | Ascher-Walsh, Charles, M.D. | Completed | No outcome recorded |
Press releases naming this drug 1 release
| Date | Issuer | Release |
|---|---|---|
| 2011-05-18 | Daiichi Sankyo | Regency Therapeutics and Daiichi Sankyo Announce Launch and Commercial Availability of SPRIX(R) (ketorolac tromethamine) Nasal Spray daiichisankyo.com ↗ |
Evidence & citations 24 cited values
Every value below carries the sentence it was read from. 454 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | ketorolac | “The purpose of this study is to compare the effectiveness of the NSAID ketorolac tromethamine ophthalmic solution 0.4% with the steroid loteprednol etabonate ophthalmic...” NCT00366691 ↗441“The pain cocktail includes three medications: ropivacaine (a local anesthetic), ketorolac (an anti-inflammatory medication), and epinephrine (a medication to constrict blood...” NCT04074265 ↗ “The NSAID group will receive 30 mg of intravenous (IV) ketorolac (Ketorolac 30 mg/ml dose vial, NDC 00409-3795-01; manufacturer: Hospira) administered up to two hours prior to...” NCT01789216 ↗ “Ketorolac is a non-steroidal anti-inflammatory drug (NSAID) that has an analgesic efficacy similar to commonly used opioids, and that recently has found wide acceptance in the...” NCT05194904 ↗ “Conventional treatment involves handling analgesic with non-steroidal anti-inflammatory drugs (paracetaol, metamizol and ketorolac) as prescribed by the doctor surgeon...” NCT02563587 ↗ “Injection Cocktail includes: 10mg Morphine, 30mg Ketorolac, 3.5ug/ml (385ug total) of Ropivicaine, 2.5ug /ml (275ug total) Epinephrine with the remainder of the solution made...” NCT01667445 ↗ “A standard joint injection of 100ml (Clonidine 80 mcg, Epinephrine 0.5mg, Ketorolac 30mg, Ropivacaine 246.25mg, and Sodium Chloride 0.9% 48.45 ml) will be injected into the...” NCT02682498 ↗ “Each vial contains a nominal 4.5 mL solution containing 60.75 millimolar (mM) phenylephrine hydrochloride (HCl) and 11.25 mM ketorolac tromethamine formulated in a 20 mM sodium...” NCT01579565 ↗ “The investigators will administer to every patient: cefazolin 2g iv bolus, ketorolac 30 mg iv bolus, pantoprazole 40 mg iv bolus, paracetamol 1g iv perfusion (initiated 30...” NCT02502877 ↗ “Each vial contains a nominal 4.5-mL solution containing 60.75 mM phenylephrine HCl (12.37 mg/mL) and 11.25 mM ketorolac trometamol (4.24 mg/mL) formulated in a 20 mM sodium...” NCT02093689 ↗ “Following assessment of eligibility and documentation of consent to participate in the study, participants will be randomized to receive intraoperative Ketorolac Tromethamine...” NCT03111381 ↗ “Anesthesia will be maintained with Sevoflurane, Magnesium, Lidocaine, Ketamine, Decadron, Ondansetron, and Ketorolac at a concentration range/dose(s) based on the clinical need...” NCT03367988 ↗ “"5％ Ketorolac Tromethamine" , " Acular® " spray by mouth . Before intubation, each endotracheal tube cuff was scattered 10 times of spray by physicians that might cover 20 cm...” NCT02608788 ↗ “periarticular injection of 50 ml solution which contains ropivacaine 15 mg, epinephrine 0.3 mg, cefmetazole 1000mg, ketorolac 30 mg and morphine HCL 10mg before closure of...” NCT01112436 ↗ “Intranasal ketorolac (SprixTM) is an FDA approved pain formulation for short term management (5 days) of moderate to moderately severe pain that requires analgesia at the opioid level.” NCT01736358 ↗ “The peri-articular infiltration of multimodal agents will consist of 150 mg of levobupivacaine, 10 mg morphine and 30mg ketorolac diluted in 0.9% saline to make a volume 100 ml.” NCT01560767 ↗ “experimental group (periarticular injection of bupivacaine, ketorolac, morphine, and epinephrine in saline; 80cc plus 1.3% liposomal bupivacaine 20cc; total injection 100cc).” PMID 28478185 ↗ Apr 2017 “Morphine 5 mg, ropivacaine 150 mg, tramadol 40 mg, epinephrine 1 mg, ketorolac 60 mg, and ketamine 1 g will be mixed with normal saline to prepare a total volume of 60 ml” NCT06113497 ↗ “Intra-operative popliteal nerve block from the surgeon: 20mL 0.2% ropivacaine and a peri-articular injection of 10mg morphine, 30mg ketorolac and 40mg methylprednisolone.” NCT02219087 ↗ “ketorolac 30 mg intravenous (IV) every six hours for patients younger than 65 years old or ketorolac 15mg IV every six hours for those older than 65 years old” NCT05393414 ↗ “In group A (active), 200 mg ropivacaine, 30 mg ketorolac, and 0.5 mg epinephrine (total volume 106 mL) were infiltrated intraoperatively into the soft tissue” PMID 19404806 ↗ Apr 2009 “ketorolac 1mg/kg every 8 hours or metamizol 15 mg/kg every 8 hrs and intravenous opioids (buprenorphine 3 mcg / kg or tramadol 1mg/ kg in continuos infusion” NCT02617199 ↗ “PCA device containing sufentanil (3 mcg/kg), ramosetron (NaseaTM) 0.3 mg and ketorolac 120 mg in a normal saline with a total volume of 100ml was connected.” NCT03171610 ↗ “continuous wound inflitration with ropivacaine + tramadol patient-controlled analgesia + additional ketorolac or propacetamol for postoperative 48 hour” NCT02012244 ↗ “The "conventional" topical medication regimen will include prednisolone acetate 1% QID, ketorolac 0.5% QID , and moxifloxacin 0.5% topical drops QID.” NCT07276802 ↗ “Periarticular infiltration solution containing 400 mg Ropivicaine, 30 mg Ketorolac, 5 mg Epidural Grade Morphine, and 0.6 ml of 1:1000 Epinephrine” NCT00869037 ↗ “Intraoperative administration intravenous of dipyrone 30-50 mg/Kg and or intravenous ketoprofen 100 mg or diclofenac 75 mg or ketorolac 30 mg” NCT01734954 ↗ “The local anesthetic group will be injected with ropivacaine 2mg/mL (3mg/kg), epinephrine 1mg/mL (0.5mg), and ketorolac 30mg/mL (0.5mg/kg).” NCT06189781 ↗ “Systemic analgesia (SA) group continue to receive 1gm paracetamol and 30 mg ketorolac by intravenous infusion every 6 hours for 3 days.” NCT04482192 ↗ “Local multimodal analgesia composition will include 5mg of morphine, 500 mg of epinephrine, 15mg of ketorolac, and 20mg of bupivacaine.” NCT05019638 ↗ “The proposed study will compare the efficacy of Triamcinolone versus Ketorolac for intra-articular injection of the knee and shoulder” NCT03616340 ↗ “Drugs: acetylcholine, isoproterenol, bradykinin, adenosine triphosphate, barium chloride, L-N-monomethyl Arginine Acetate, ketorolac.” NCT02833207 ↗ “* patients in the TIVA NoNarc group will receive propofol, dexmedetomidine, ketamine, ketorolac and acetaminophen intraoperatively” NCT01449708 ↗ “Eyes were randomized to ketorolac tromethamine, 0.45% (Acuvail), or placebo 4 times daily for 3 days before pars plana vitrectomy.” PMID 24336915 ↗ Jan 2014 “The injectant mixture consists of ropivacaine 300 mg mixed with 30 mg ketorolac and 0.5 mg epinephrine, total volume 156 mL.” NCT01782781 ↗ “Ketorolac 0.5% ophthalmic solution: one drop to the operative eye four times daily for 1 month or until the bottle runs out” NCT05157113 ↗ “A total of three microdialysis sites will be perfused with ringer's solution, L-NAME, or ketorolac (one drug per site).” NCT06911372 ↗ “1gm of paracetamol, 30mg of ketorolac and 1mg Granitryl will be given twenty minutes before the end of the operation .” NCT06502067 ↗ “1g of IV paracetamol and 30 mg of IV Ketorolac will be given if intra-operative course suggest inadequate analgesia” NCT06202664 ↗ “For the subjects of GI nano-ketorolac gel (Around 2mm3), placed as medicament inside the root canal for one week.” NCT07064083 ↗ “Ketorolac 30 mg in 10 ml saline will be injected at the incision sites at the conclusion of the procedure.” NCT01374828 ↗ “ketorolac, a nonsteroidal anti-inflammatory drug, has been approved for postoperative pain management.” PMID 38335521 ↗ Feb 2024 “standard care which includes ketorolac, bupivacaine, fentanyl, ondansetron, dexamethasone, sevoflurane” NCT01868425 ↗ “Ketorolac 30 mg, Morphine PF 5 mg, Epinephrine 0.6 mg, Ropivacaine 400 mg, QS to 100ml with 0.9% NaCl” NCT02299349 ↗ “Patients in Group B received injection ketorolac 30mg intravenously every 8 hours following surgery.” NCT06608056 ↗ “Subjects will be given a rectus sheath block containing dexmedetomidine, ropivacaine, and ketorolac” NCT03817034 ↗ “2.5mg morphine, 40 micrograms clonidine, 15mg ketorolac, and 4ml normal saline (deep injection).” NCT05037812 ↗ “The injection contained 150mg bupivacaine (3mg/mL), 60mg ketorolac(1.2mg/mL) and 1mg morphine.” NCT06630520 ↗ “ST will consist of 975mg of Acetaminophen PO and either 30mg of Ketorolac IM or 15 mg IV.” NCT04704297 ↗ “Group III: (n=20) received IV 30 mg ketorolac tromethamine (ketorolac ®, Amriya Pharma).” NCT02449954 ↗ “Pain will be managed with Acetaminophen 1000mg q8 hours, Ketorolac 10mg every 6 hours” NCT04990804 ↗ “in combination 30 mg ketorolac and Single preoperative 0.1 mg/kg dose dexamethasone” NCT04238377 ↗ “Intraosseous injection of Ketorolac 15mg and Tranexamic acid 500mg in femoral canal” NCT06243575 ↗ “Pre-treatment analgesia (combination of ondansetron, ketorolac, and hydromorphone)” NCT01993238 ↗ “paracetamol 1g IV and ketorolac 30 mg IV in 100 mL normal saline intraoperatively” NCT07299630 ↗ “IV formulation: ketorolac 0.5mg/kg/dose, 15mg maximum, no more than 8 doses total” NCT06860711 ↗ “When not contraindicated, 30 mg IV ketorolac will be given at the end of surgery.” NCT01507246 ↗ “When not contraindicated, 30 mg IV ketorolac will be given at the end of surgery.” NCT02058290 ↗ “Postoperative analgesia includes paracetamol + ketorolac/parecoxib + metamizole,” NCT07337135 ↗ “medications such as Gabapentin, Tylenol, Meloxicam, Bupivacaine, or Ketorolac.” NCT04176783 ↗ “Adolor ( ketorolac) 15\_30 mg IV every 6 hours up to 5 days post-operation” NCT07032883 ↗ “Ropivacaine and Adrenalin, systemic Ketorolac and high dose Dexamethasone” NCT02374008 ↗ “Phenylephrine and Ketorolac infusion of 1%/0.3% during cataract surgery.” NCT03864133 ↗ “Ketorolac (Brand Names: Toradol, Sprix, Acuvail, Acular) 30 mg/ml (1 ml)” NCT02571283 ↗ “IV ketorolac 30 mg every 8 hours for 24 hours then 15 mg every 8 hours;” NCT07658521 ↗ “systemic analgesia using IV Ketorolac injection will be used on demand” NCT06462573 ↗ “patients will receive ketorolac 30mg IV, neuromuscular reversal agents” NCT01566838 ↗ “Acetaminophen 1 gm and Ketorolac 30 mg in 100 mL i.v. over 10 minutes” NCT04648540 ↗ “150mL 2% Ropivacaine, 30mg Ketorolac and 0.6mg of Epinephrine” NCT02760043 ↗ “Ketorolac 0.75 mg/ Kg and paracetamol 10 mg/ Kg intravenously” NCT04302129 ↗ “intravenous paracetamol and ketamine followed by ketorolac” NCT03580980 ↗ “NSAIDs used is ketorolac, with dose of 30 mg every 8 hours” NCT06750627 ↗ “2.88 mg/mL (0.3% w/v) of ketorolac {Generic Name: TORADOL}” NCT06539637 ↗ “phenylephrine 1% and ketorolac 0.3% intraocular solution” NCT04316936 ↗ “using ropivacaine, epinephrine, ketorolac, and morphine” PMID 24706022 ↗ Jan 2015 “Ketorolac 30 mg i.v. infusion in100 ml over 10 minutes.” NCT04941040 ↗ “and after wound closure ketorolac 30 mg intravenously” NCT01513564 ↗ “Ropivacaine 0.2% Ketorolac 30 mg Adrenaline 0.1 mg/ml” NCT01281891 ↗ “children who received 0.25% Ketorolac for myopia” NCT03402100 ↗ “NSAIDs(ketorolac IV15-30mg every 6 postoperative” NCT05474040 ↗ “IV ketorolac 30 mg every 8 hours PRN (NRS \>4)” NCT07268911 ↗ “Ketorolac, Diphenhydramine and Metoclopramide” NCT01604785 ↗ “30 mg ketorolac (Caspian Tamin, Rasht, Iran)” NCT05324995 ↗ “3. Ketorolac oral 10 mg TID (#15, refill #0)” NCT03738904 ↗ “same ketorolac 30mg x 9 doses every 6 hours” NCT03330119 ↗ “Ketorolac (Kelac) 0.5% ophthlmic solution” NCT01769352 ↗ “IV acetaminophen 1g + IV ketorolac 30mg” NCT03534895 ↗ “ketorolac 30 mg IV, ondansetron 4mg IV” NCT03448068 ↗ “30 mg Toradol/ketorolac (30mg/ml)” NCT07151417 ↗ “intravenous Ketorolac (Toradol)” NCT06570577 ↗ “2. Ketorolac 30mg/ml - 1 ml” NCT03105674 ↗ “Ketorolac 20mg orally x 1” NCT05239767 ↗ “paracetamol , Ketorolac” NCT03106818 ↗ “ketorolac 1 mL (30 mg)” NCT01898052 ↗ “30 mg of Ketorolac” NCT04112160 ↗ “Drug: Ketorolac” NCT03472872 ↗ “Ketorolac” NCT03885596 ↗ |
| Known as | Acular | “"5％ Ketorolac Tromethamine" , " Acular® " spray by mouth . Before intubation, each endotracheal tube cuff was scattered 10 times of spray by physicians that might cover 20 cm...” NCT02608788 ↗2“plus Ketorolac tromethamine 0.5% (Acular®, Allergan), one drop three times/day” NCT00992355 ↗ “topical ketorolac 0.5% (Acular®, Allergan Inc, Irvine, CA)” NCT01761071 ↗ |
| Known as | Acular LS | “NSAID eye drop: Acular LS” NCT01673191 ↗ |
| Known as | Acuvail | “PURPOSE: To evaluate the efficacy and safety of twice-daily, preservative-free ketorolac 0.45% (Acuvail; Allergan, Inc, Irvine, California, USA) administration for treatment of...” PMID 21145532 ↗ Dec 20101“Eyes were randomized to ketorolac tromethamine, 0.45% (Acuvail), or placebo 4 times daily for 3 days before pars plana vitrectomy.” PMID 24336915 ↗ Jan 2014 |
| Known as | Adolor | “Adolor ( ketorolac) 15\_30 mg IV every 6 hours up to 5 days post-operation” NCT07032883 ↗ |
| Known as | Dolac | “The ketorolac group (Dolac, Siegfried Rhein, Mexico) was instructed to take their 10-mg tablets every 8 hours on the day of surgery and for the first 3 postoperative days.” NCT02867176 ↗ |
| Known as | IV-K | “Intravenous Ketorolac (IV-K)” NCT06994442 ↗ |
| Known as | Kelac | “Ketorolac (Kelac) 0.5% ophthlmic solution” NCT01769352 ↗ |
| Known as | Ketolac | “Oral Paracetamol (500mg/6hr), IV Ketolac (15mg/6hr) and IV perfelgan (1gm/6hr)” NCT06958549 ↗ |
| Known as | ketorolac acetate | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00707421 ↗ |
| Known as | Ketorolac Injectable Solution | “Drug: Ketorolac Injectable Solution” NCT02953210 ↗ |
| Known as | Ketorolac Trometamol | “Ketorolac Trometamol 5 mg/ml eye drops, solution” NCT00405730 ↗1“Ketorolac Trometamol 30Mg/1mL Injection” NCT03638999 ↗ |
| Known as | Ketorolac Tromethamine | “This group receives Ketorolac Tromethamine 0.5 mg/kg IV up to a maximum dose of 30mg, in the form of Ketorolac Tromethamine solution for IV/IM use 30mg/ml single dose vial at...” NCT03453541 ↗32“TORADOL (ketorolac tromethamine), is a nonsteroidal anti-inflammatory drug (NSAID), is indicated for the short-term (up to 5 days in adults), management of moderately severe...” NCT03669081 ↗ “PURPOSE: To evaluate whether adding perioperative topical ketorolac tromethamine 0.4% improves cataract surgery outcomes relative to topical steroids alone in patients without...” PMID 18599019 ↗ Jul 2008 “Following assessment of eligibility and documentation of consent to participate in the study, participants will be randomized to receive intraoperative Ketorolac Tromethamine...” NCT03111381 ↗ “"5％ Ketorolac Tromethamine" , " Acular® " spray by mouth . Before intubation, each endotracheal tube cuff was scattered 10 times of spray by physicians that might cover 20 cm...” NCT02608788 ↗ “Ketorolac tromethamine is a nonsteroidal anti-inflammatory drug (NSAID) that is extensively used for the management of renal colic in the emergency department (ED).” PMID 33370510 ↗ Feb 2021 “Ketorolac tromethamine (Toradol) is a parenteral, nonsteroidal anti-inflammatory drug that has been used extensively to provide postoperative analgesia.” NCT01498796 ↗ “Once the microcatheter is in a good position, 15 mg Dexamethasone Sodium Phosphate and 15 mg of Ketorolac Tromethamine will be infused over 30 minutes.” NCT04353505 ↗ “olopatadine hydrochloride/ketorolac tromethamine fixed dose combination ophthalmic solution administered to each eye, twice daily for 21 days.” NCT01258309 ↗ “Treatment of Acute Pseudophakic Cystoid Macular Edema: Bromfenac 0.09% Versus Diclofenac Sodium 0.1% Versus Ketorolac Tromethamine 0.5%” NCT00595543 ↗ “Eyes were randomized to ketorolac tromethamine, 0.45% (Acuvail), or placebo 4 times daily for 3 days before pars plana vitrectomy.” PMID 24336915 ↗ Jan 2014 “Patients will receive 10 mg film-coated tablets of ketorolac tromethamine three times a day, for five days before the surgery” NCT06150898 ↗ “Among NSAIDS, Ketorolac tromethamine (Toradol) is the first approved for parenteral use in 1990 in the United States.” NCT05074056 ↗ “Group III: (n=20) received IV 30 mg ketorolac tromethamine (ketorolac ®, Amriya Pharma).” NCT02449954 ↗ “Ketorolac Tromethamine 1 mg/kg infusion over 10 minutes intravenous (IV) infusion.” NCT01260883 ↗ “plus Ketorolac tromethamine 0.5% (Acular®, Allergan), one drop three times/day” NCT00992355 ↗ “Ketorolac Tromethamine - single dose (15 mg) administered intranasally (IN)” NCT01363076 ↗ “Ketorolac tromethamine 0.5% (Acular®, Allergan), one drop three times/day” NCT01103401 ↗ “Topical ketorolac tromethamine {TORADOL, Nonsteroidal Anti-inflammatory}” NCT06539637 ↗ “group 2 received ketorolac tromethamine 0.4% (Acular LS, Allergan)” PMID 25385061 ↗ Nov 2014 “Regimen A: Ketorolac tromethamine (Gentle Sniff - Upright)” NCT01356212 ↗ “Ketorolac tromethamine ophthalmic solution 0.45%” NCT02646072 ↗ “Ketorolac Tromethamine ophthalmic solution 0.4%” NCT00332774 ↗ “30 mg of ketorolac tromethamine (Normon Spain)” NCT05248724 ↗ “30 mg Ketorolac Tromethamine intranasal (IN)” NCT01355588 ↗ “ketorolac tromethamine 30 mg; or placebo.” PMID 22886837 ↗ Aug 2012 “SPRIX(intranasal ketorolac tromethamine)” NCT02102516 ↗ “Drug: Intranasal Ketorolac Tromethamine” NCT07305883 ↗ “Intranasal Ketorolac tromethamine” NCT01356225 ↗ “Drug: Ketorolac Tromethamine” NCT01365650 ↗ “Drug: Ketorolac Tromethamine” NCT02729285 ↗ “Drug: Ketorolac Tromethamine” NCT05336266 ↗ “Drug: Ketorolac Tromethamine” NCT01291472 ↗ |
| Known as | Ketorolac/Toradol (NDC 00409-3795-01; manufacturer: Hospira) | “Ketorolac/Toradol (NDC 00409-3795-01; manufacturer: Hospira)” NCT01789216 ↗ |
| Known as | PRO-156 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01871077 ↗ |
| Known as | SPRIX | “SPRIX(intranasal ketorolac tromethamine)” NCT02102516 ↗ |
| Known as | SPRIX(R) | “Efficacy and tolerability of intranasal ketorolac (SPRIX(R)) was assessed in abdominal surgery patients.” PMID 20557145 ↗ Aug 2010 |
| Known as | Toradol | “Following assessment of eligibility and documentation of consent to participate in the study, participants will be randomized to receive intraoperative Ketorolac Tromethamine...” NCT03111381 ↗12“To determine if Celebrex (Celecoxib) is as effective as Toradol (Ketorolac) at controlling postoperative pain when given in addition to standard postoperative pain control regimens.” NCT03331315 ↗ “Other pain medicines, like acetaminophen (also called Tylenol) and ketorolac (also called Toradol), are available but aren't commonly used because we don't know if they help.” NCT06994442 ↗ “Multimodal local injection of bupivacaine (Marcaine), morphine sulfate (Duramorph), ketorolac (Toradol) given at the fracture site at the time of hip fracture surgery” PMID 37199438 ↗ Sep 2023 “Ketorolac tromethamine (Toradol) is a parenteral, nonsteroidal anti-inflammatory drug that has been used extensively to provide postoperative analgesia.” NCT01498796 ↗ “Patients assigned to Toradol group will receive a single dose of 60mg of Ketorolac (Toradol) mixed with 8mL of 1% lidocaine with epinephrine 1:100,000.” NCT03319784 ↗ “Among NSAIDS, Ketorolac tromethamine (Toradol) is the first approved for parenteral use in 1990 in the United States.” NCT05074056 ↗ “IV Ketorolac (Toradol) will be administered at conclusion of oocyte retrieval.” NCT06026553 ↗ “Topical ketorolac tromethamine {TORADOL, Nonsteroidal Anti-inflammatory}” NCT06539637 ↗ “Toradol is a type of brand name. We will be using the generic version.” NCT03535116 ↗ “30 mg Toradol/ketorolac (30mg/ml)” NCT07151417 ↗ “intravenous Ketorolac (Toradol)” NCT06570577 ↗ “Toradol” NCT02266433 ↗ |
| Known as | Toradol (ketorolac) | “Toradol (ketorolac)” NCT05019638 ↗1“Toradol (ketorolac)” NCT05037812 ↗ |
| Action | Inhibit | “Ketorolac is a 7-fold selective inhibitor of cyclooxygenase-2 (Cox-2)” NCT00001698 ↗ |
| Modality | Other / unclassified | “a non steroidal anti-inflammatory drug (ketorolac)” NCT01281891 ↗ |
| Route | Oral | “ketorolac tromethamine oral rinse” NCT00001698 ↗ |
| Target | CDC42 | “time-dependent inhibition of Rac1 and Cdc42 GTPase activity” NCT02470299 ↗ |
| Target | RAC1 | “time-dependent inhibition of Rac1 and Cdc42 GTPase activity” NCT02470299 ↗ |