Nonopioid Analgesia After Anterior Cruciate Ligament Reconstruction
Summary
This is a randomized, single blinded, standard of care controlled clinical trial. This project aims to compare postoperative pain control in patients in two treatment arms of anterior cruciate ligament reconstruction: a treatment group given a nonopioid pain control regimen, and a standard of care control group given standard opioid pain control regimen
Timeline
- Start
- 2019-01-22
- Primary completion
- 2020-01-20
- Completion
- 2020-05-20
Outcome
Mixed primary results
registry MEAN Post-Operative Non Opioid Pain Protocol: 2.5 (2.29 to 2.71) score on a scale (0-10 on VAS pain scale NCT03818932 ↗
registry analysis (superiority test); Post-Operative Non Opioid Pain Protocol vs Post-Operative Traditional Pain Protocol; p <0.001; t-test, 2 sided NCT03818932 ↗
registry MEAN Post-Operative Non Opioid Pain Protocol: 61.4 (Standard Deviation 8.9) score on a scale NCT03818932 ↗
registry MEAN Post-Operative Traditional Pain Protocol: 66.3 (Standard Deviation 8.2) score on a scale NCT03818932 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Acetaminophen | Small molecule | — | — |
| Subject | Celecoxib | Other / unclassified | — | — |
| Subject | Diazepam | Small molecule | — | — |
| Subject | Gabapentin | Unknown | — | — |
| Comparator | Hydrocodone-Acetaminophen | Unknown | — | — |
| Subject | Ketorolac | Other / unclassified | — | — |
Indications
No indication recorded.