drugset / Trial / NCT03105674

Multi-Drug Analgesia vs. Standard Solution for Anal Surgery

NCT03105674

Phase 4 Withdrawn Columbia University
RandomizedParallel-groupQuadruple-blindSupportive care

Summary

The primary aim is to test the magnitude and duration of analgesia provided by single dose multi-drug analgesia administered for perianal block, and compare with standard solution (Marcaine \& Lidocaine in 1:1 mixture - Total 60 ml), at post-operative period and also to compare with the standard solution including their respective post-operative opioid or non-opioid oral analgesic requirement. Local anesthesia via a perianal block using multi-drug analgesia or standard solution will be compared using the Numeric pain rating scale on Post-operative day 1, 3 and during follow up visit on day 7. The investigators hope to find a better control of post-operative analgesia which will lead to better functional outcomes. Possible decrease consumption of opioids in the post-operative period will perhaps decrease the cost and chances of addiction and will increase patient comfort and compliance.

Timeline

Start
2017-05-01
Primary completion
2017-11
Completion
2017-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Bupivacaine Other / unclassified Other
Subject Epinephrine Other / unclassified Other
Subject Ketorolac Other / unclassified 1 ml Other
Comparator Lidocaine Other / unclassified 20 ml Other
Comparator Lidocaine Other / unclassified Other
Subject Ropivacaine Other / unclassified 30 ml Other
Subject Triamcinolone Acetonide Other / unclassified 5 ml Other