Multi-Drug Analgesia vs. Standard Solution for Anal Surgery
Summary
The primary aim is to test the magnitude and duration of analgesia provided by single dose multi-drug analgesia administered for perianal block, and compare with standard solution (Marcaine \& Lidocaine in 1:1 mixture - Total 60 ml), at post-operative period and also to compare with the standard solution including their respective post-operative opioid or non-opioid oral analgesic requirement. Local anesthesia via a perianal block using multi-drug analgesia or standard solution will be compared using the Numeric pain rating scale on Post-operative day 1, 3 and during follow up visit on day 7. The investigators hope to find a better control of post-operative analgesia which will lead to better functional outcomes. Possible decrease consumption of opioids in the post-operative period will perhaps decrease the cost and chances of addiction and will increase patient comfort and compliance.
Timeline
- Start
- 2017-05-01
- Primary completion
- 2017-11
- Completion
- 2017-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Bupivacaine | Other / unclassified | — | Other |
| Subject | Epinephrine | Other / unclassified | — | Other |
| Subject | Ketorolac | Other / unclassified | 1 ml | Other |
| Comparator | Lidocaine | Other / unclassified | 20 ml | Other |
| Comparator | Lidocaine | Other / unclassified | — | Other |
| Subject | Ropivacaine | Other / unclassified | 30 ml | Other |
| Subject | Triamcinolone Acetonide | Other / unclassified | 5 ml | Other |