Drugs / Bupivacaine
last change 3 days ago re-read 2 minutes ago

Bupivacaine

English name bupivacaine

Other / unclassified

Developed for
neuropathy, painful · osteoarthritis, knee · chronic pain syndrome · substance-related disorder · migraine disorder · rotator cuff syndrome · arthropathy · osteoarthritis
+140 more · pelvic organ prolapse · lumbar disk disease · appendicitis · carpal tunnel syndrome · osteoarthritis, hip · atrial fibrillation · female stress incontinence · headache disorder · pregnancy disorder · toe, misshapen · abdominal wall malformation · chronic pancreatitis · gallbladder disorder · heart disorder · hemorrhoid · hypotensive disorder · local anesthetic poisoning · nephrolithiasis · postherpetic neuralgia · radiculopathy · spondylolisthesis · urethral stricture · acquired aneurysmal subarachnoid hemorrhage · adolescent idiopathic scoliosis · bone disorder · cardiac rhythm disease · cardiac valvular defect · cataract · complex regional pain syndrome · delirium · dysautonomia · hypospadias · impacted teeth, multiple · lumbar spinal stenosis · lymphedema · myofascial pain syndrome · palmar fibromatosis · paralytic ileus · post-traumatic stress disorder · ptosis · pulpitis · tonsillitis · vertebral column disorder · adenomyosis · anal fistula · arthritic joint disease · Bell's palsy · biliary tract disorder · breast disorder · cervical disk degenerative disorder · cleft palate · colorectal cancer · COVID-19 · cranial neuralgia · CREST syndrome · dementia · dental pulp disorder · diffuse scleroderma · disease of the tendon · endometriosis · epicondylitis · esotropia · excessive tearing · exotropia · fibromyalgia · frozen shoulder · gallstones · ganglion or cyst of synovium/tendon/bursa · gastric adenoma · gastric cancer · Graves disease · hernia, double inguinal · herpes zoster · interstitial cystitis · intervertebral disk degenerative disorder · intracranial vasospasm · juvenile idiopathic scoliosis · large intestine disorder · major depressive disorder · malignant pancreatic neoplasm · movement disorder · mucositis · musculoskeletal system disorder · myalgic encephalomeyelitis/chronic fatigue syndrome · myopathy, congenital, with respiratory insufficiency and bone fractures · nasal disorder · neurological pain disorder · obstetric disorder · osteoarthritis, hand · osteoarthritis, toe · osteoporosis · pain agnosia · peripheral nerve lesion · polyp of vocal cord · post-infectious syndrome · post-viral disorder · postpartum depression · prolapse of female genital organ · proliferative diabetic retinopathy · pudendal neuralgia · Raynaud disease · restless legs syndrome · rheumatic disorder · scoliosis · skin infection · soft tissue neoplasm · spondylosis · strabismus · subarachnoid hemorrhage · tarsal coalition · tendinitis · uterine benign neoplasm · Alzheimer disease · BD syndrome · benign neoplasm · bicipital tenosynovitis · body integrity dysphoria · cerebral palsy · cervical incompetence · cervical vertebral Bridge · cholecystitis · cluster headache syndrome · developmental dysplasia of the hip · flushing of ears and somnolence · hyperhidrosis palmaris ET plantaris · ileus · levator syndrome · lumbar disk degenerative disorder · neuralgia · neuroma · pancreatitis · paroxysmal Hemicrania · pectus excavatum · secondary erythromelalgia · shoulder impingement syndrome · spinal polio · tibial collateral ligament bursitis · urinary bladder disorder · uterine corpus leiomyoma · vertebral disorder
Investigated by
Pacira Pharmaceuticals, Inc · Mayo Clinic · Cairo University · Icahn School of Medicine at Mount Sinai · Innocoll · Ain Shams University
+568 more · Assiut University · Tanta University · Wake Forest University Health Sciences · Johns Hopkins University · The Cleveland Clinic · Duke University · Federal University of São Paulo · Heron Therapeutics · Montefiore Medical Center · University of Minnesota · Durect · Henry Ford Health System · Hospital for Special Surgery, New York · M.D. Anderson Cancer Center · Mahidol University · Mansoura University · McMaster University · NYU Langone Health · Premier Research · University of Alabama at Birmingham · University of Wisconsin, Madison · Yale University · Cristália Produtos Químicos Farmacêuticos Ltda. · Hadassah Medical Organization · Indonesia University · Maimonides Medical Center · Registrat-Mapi · Samuel Lunenfeld Research Institute, Mount Sinai Hospital · TriHealth Inc. · University of Aarhus · University of California, San Diego · University of North Carolina, Chapel Hill · University of Texas Southwestern Medical Center · Washington University School of Medicine · Beijing Tiantan Hospital · Beth Israel Deaconess Medical Center · Brigham and Women's Hospital · George Washington University · Hartford Hospital · Huazhong University of Science and Technology · Kasr El Aini Hospital · Loyola University · Medical University of Silesia · National Cancer Institute (NCI) · Northwestern University · Nycomed · Silesian University of Medicine · Sohag University · St. Joseph's Healthcare Hamilton · St. Luke's Hospital, Pennsylvania · The University of Hong Kong · The University of Texas Health Science Center, Houston · University Health Network, Toronto · University of California, San Francisco · University of South Florida · University of Southern California · University of Virginia · Yonsei University · Bozyaka Training and Research Hospital · Cedars-Sinai Medical Center · Emory University · Fayoum University Hospital · Indiana University · King Saud University · Marmara University · Massachusetts General Hospital · Nanjing First Hospital, Nanjing Medical University · OhioHealth · OrthoCarolina Research Institute, Inc. · Ottawa Hospital Research Institute · Regionshospitalet Silkeborg · Seoul National University Hospital · Thomas Jefferson University · University of British Columbia · all 574 on the full record

Regulatory milestones approvals, filings & regulatory actions · 5 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Label expansions (3) US (FDA) EXPAREL 2018-04-06 – 2023-11-09 fda.gov
Approved EU (EMA) Zynrelef 2020-09-24 europa.eu
Approved US (FDA) MARCAINE HYDROCHLORIDE W/ EPINEPHRINE PRESERVATIVE FREE 1972-10-03 fda.gov

Trials 817 · started per year

today
US approved 1972
EU approved 2020
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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 029 trials
Phase 0 NCT07643506 Jun 2026 → Jun 2027 expected University of Calgary Not yet recruiting No outcome recorded
Phase 0 NCT07245290 Nov 2025 → Jun 2026 overdue Second Affiliated Hospital, School of Medicine, Zhejiang University Not yet recruiting No outcome recorded
Phase 0 NCT06349772 Nov 2024 → Nov 2027 expected Texas Tech University Health Sciences Center Recruiting No outcome recorded
Phase 0 NCT06462573 Sep 2024 → Sep 2026 expected ureterolithiasis Assiut University Not yet recruiting No outcome recorded
Phase 0 NCT05461092 Jan 2024 → Dec 2026 expected delirium University of Iowa Recruiting No outcome recorded
Phase 0 NCT05925478 Nov 2023 → Aug 2024 acquired aneurysmal subarachnoid hemorrhage University of Texas Southwestern Medical Center Completed No outcome recorded
Phase 0 NCT05794828 Sep 2023 → Feb 2025 The University of Texas Health Science Center at San Antonio Completed No outcome recorded
Phase 0 NCT06293807 Jun 2022 → Apr 2023 periodontal disorder The University of Texas Health Science Center at San Antonio Completed No outcome recorded
Phase 0 NCT05122351 Oct 2021 → Dec 2022 Sohag University Completed No outcome recorded
Phase 0 NCT05097118 Sep 2021 → May 2022 appendicitis Sohag University Completed No outcome recorded
Phase 131 trials
Phase 1 NCT05575999 Jan → Oct 2026 expected Kansas City Heart Rhythm Research Foundation Not yet recruiting No outcome recorded
Phase 1 NCT07429448 Dec 2025 → Jun 2026 overdue appendicitis Sardar Umer Rehman Recruiting No outcome recorded
Phase 1 NCT06500286 Aug 2024 → Mar 2025 overdue Assiut University Not yet recruiting No outcome recorded
Phase 1 NCT06069791 Jan 2024 → Dec 2026 expected Yale University Recruiting No outcome recorded
Phase 1 NCT06274008 Oct 2023 → Oct 2024 anxiety, opioid abuse Children's Hospital of Orange County Unknown No outcome recorded
Phase 1 NCT04908449 Jun 2023 → Nov 2024 coronary artery disorder, respiratory failure Medical College of Wisconsin Completed No outcome recorded
Phase 1 NCT05906433 Jun 2023 → Jun 2025 overdue osteoarthritis, knee Foundation for Orthopaedic Research and Education Recruiting No outcome recorded
Phase 1 NCT05664711 Mar → Dec 2023 myalgic encephalomeyelitis/chronic fatigue syndrome, post-infectious syndrome, post-viral disorder Neuroversion, Inc. Completed No outcome recorded
Phase 1 NCT06620614 Oct → Dec 2022 benign prostatic hyperplasia National Academy of Medical Sciences, Nepal Completed No outcome recorded
Phase 1 NCT05517486 Jul → Aug 2022 postherpetic neuralgia Grace Therapeutics Inc. Unknown No outcome recorded
Phase 1/26 trials
Phase 1/2 NCT04168710 May 2025 → May 2027 Yale University Withdrawn No outcome recorded
Phase 1/2 NCT06809998 Jan 2025 → Aug 2026 overdue osteoarthritis, knee Unity Health Toronto Recruiting No outcome recorded
Phase 1/2 NCT03780478 Jun 2019 → Dec 2021 University of Southern California Unknown No outcome recorded
Phase 1/2 NCT03040011 Jun 2017 → Apr 2019 pelvic organ prolapse Lauren Giugale, MD Completed No outcome recorded
Phase 1/2 NCT02214810 Jan → Sep 2015 Broward Health Withdrawn No outcome recorded
Phase 1/2 NCT01477190 Oct 2010 → Oct 2011 colon carcinoma, diverticulitis, inflammatory bowel disease McGill University Health Centre/Research Institute of the McGill University Health Centre Completed No outcome recorded
Phase 274 trials
Phase 2 NCT07201987 Jan 2027 → Jan 2028 expected Ganesh M. Shankar Not yet recruiting No outcome recorded
Phase 2 NCT07366905 Feb → Mar 2026 Hainan Medical College Completed No outcome recorded
Phase 2 NCT06734975 Jul 2025 → Dec 2026 expected polyp of vocal cord Rutgers, The State University of New Jersey Recruiting No outcome recorded
Phase 2 NCT06635889 Mar 2025 → Oct 2029 expected nephrolithiasis University of Chicago Recruiting No outcome recorded
Phase 2 NCT06270147 Nov 2024 → Jan 2025 overdue substance-related disorder McMaster University Recruiting No outcome recorded
Phase 2 NCT06655454 Nov 2024 → Jun 2026 overdue New York University Recruiting No outcome recorded
Phase 2 NCT04744675 May → Jul 2024 overdue complex regional pain syndrome Ottawa Hospital Research Institute Active not recruiting No outcome recorded
Phase 2 NCT06429501 Apr 2024 → Feb 2027 expected Washington University School of Medicine Recruiting No outcome recorded
Phase 2 NCT06002152 Nov 2023 → Feb 2026 Yale University Completed No outcome recorded
Phase 2 NCT06411795 Nov 2023 → Jan 2027 expected pancreatic neoplasm, tumor of duodenum Masonic Cancer Center, University of Minnesota Recruiting No outcome recorded
Phase 2/321 trials
Phase 2/3 NCT07555821 Apr → Oct 2026 expected South Egypt Cancer Institute Not yet recruiting No outcome recorded
Phase 2/3 NCT06456255 Nov 2024 → May 2025 overdue hemorrhagic disease, paranasal sinus disorder Amin Javer Recruiting No outcome recorded
Phase 2/3 NCT06621329 Oct 2024 → Jul 2026 overdue headache disorder, subarachnoid hemorrhage University of California, Davis Recruiting No outcome recorded
Phase 2/3 NCT05357690 Apr 2023 → Jun 2026 atrial fibrillation Mayo Clinic Completed No outcome recorded
Phase 2/3 NCT05283980 Nov 2022 → Mar 2025 overdue neuropathy, painful, opioid abuse Beth Israel Deaconess Medical Center Active not recruiting No outcome recorded
Phase 2/3 NCT04655339 Jan 2020 → Sep 2021 substance-related disorder Baylor Research Institute Withdrawn No outcome recorded
Phase 2/3 NCT05672680 Dec 2019 → Aug 2023 Icahn School of Medicine at Mount Sinai Completed No outcome recorded
Phase 2/3 NCT03739021 Nov 2019 → Mar 2020 overdue chronic pain syndrome University of South Florida Not yet recruiting No outcome recorded
Phase 2/3 NCT03408483 Apr 2018 → May 2019 University of Alabama at Birmingham Completed No outcome recorded
Phase 2/3 NCT02495220 Jul 2015 → Nov 2017 Assiut University Unknown No outcome recorded
Phase 390 trials
Phase 3 NCT07672236 Jul → Dec 2026 expected head and neck cancer, mucositis OncoZenge AB Recruiting No outcome recorded
Phase 3 NCT07212114 Nov 2025 → Aug 2029 expected Emory University Recruiting No outcome recorded
Phase 3 NCT07092566 Nov 2025 → Oct 2027 expected renal carcinoma Wake Forest University Health Sciences Recruiting No outcome recorded
Phase 3 NCT06740214 Sep 2025 → Jun 2027 expected The University of Hong Kong Recruiting No outcome recorded
Phase 3 NCT07257874 Jul → Dec 2025 Islamabad Medical and Dental College Completed No outcome recorded
Phase 3 NCT06937385 May 2025 → May 2026 overdue cranial neuralgia, migraine disorder HCA Florida North Florida Hospital Not yet recruiting No outcome recorded
Phase 3 NCT06989866 Dec 2024 → Aug 2026 overdue United States Naval Medical Center, Portsmouth Enrolling by invitation No outcome recorded
Phase 3 NCT06665438 Dec 2024 → Apr 2025 overdue Al-Azhar University Recruiting No outcome recorded
Phase 3 NCT06695858 Nov 2024 → Oct 2025 Kasr El Aini Hospital Completed No outcome recorded
Phase 3 NCT06405724 May 2024 → Dec 2025 Feng Gao Unknown No outcome recorded
Phase 4312 trials
Phase 4 NCT07216586 Jan 2027 → Jan 2028 expected osteoarthritis, knee University of Miami Not yet recruiting No outcome recorded
Phase 4 NCT07246642 Sep 2026 → Sep 2027 expected erectile dysfunction Wake Forest University Health Sciences Not yet recruiting No outcome recorded
Phase 4 NCT07684365 Aug 2026 → Dec 2027 expected Beth Israel Deaconess Medical Center Not yet recruiting No outcome recorded
Phase 4 NCT07684989 Jul 2026 → Jun 2027 expected Mayo Hospital Lahore Not yet recruiting No outcome recorded
Phase 4 NCT07650760 Jul → Dec 2026 expected Wah Medical college , POF hospital Recruiting No outcome recorded
Phase 4 NCT07606911 Jul 2026 → Jul 2027 expected Shanghai Jiao Tong University Affiliated Sixth People's Hospital Not yet recruiting No outcome recorded
Phase 4 NCT07228039 Jul 2026 → Jan 2028 expected Duke University Not yet recruiting No outcome recorded
Phase 4 NCT07681648 Jun → Nov 2026 expected Engy Emil Enrolling by invitation No outcome recorded
Phase 4 NCT07616180 Jun → Sep 2026 expected Cairo University Not yet recruiting No outcome recorded
Phase 4 NCT07570940 Jun 2026 → Jun 2030 expected atrial fibrillation, coronary artery disorder Mayo Clinic Not yet recruiting No outcome recorded
Show all 312 trials opens the full record — a long page
Phase not applicable253 trials
NCT07661212 Sep 2026 → Sep 2027 expected Bakirkoy Dr. Dr. Sadi Konuk Research and Training Hospital Not yet recruiting No outcome recorded
NCT07658521 Jul → Dec 2026 expected Ain Shams University Enrolling by invitation No outcome recorded
NCT07651722 Jun → Sep 2026 expected paralytic ileus Tianjin First Central Hospital Recruiting No outcome recorded
NCT07577934 May → Jul 2026 overdue Tianjin First Central Hospital Recruiting No outcome recorded
NCT07579975 Apr → May 2026 overdue Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital Not yet recruiting No outcome recorded
NCT07509866 Apr → Oct 2026 expected Huazhong University of Science and Technology Recruiting No outcome recorded
NCT07338916 Apr → Nov 2026 expected Hospital del Trabajador de Santiago Recruiting No outcome recorded
NCT07458282 Mar 2026 → Mar 2027 expected Beijing Tiantan Hospital Recruiting No outcome recorded
NCT07458256 Mar 2026 → Mar 2027 expected Beijing Tiantan Hospital Recruiting No outcome recorded
NCT07440576 Mar 2026 → Feb 2027 expected pelvic organ prolapse Erkan Gol Recruiting No outcome recorded
Show all 253 trials opens the full record — a long page
Phase not stated1 trial
NCT03969875 Aug 2018 → Apr 2022 osteoarthritis Icahn School of Medicine at Mount Sinai Completed No outcome recorded
Also used as a comparator or background therapy in 1,374 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 038 trials
Phase 0 NCT07485127 Comparator Feb → Aug 2026 overdue Sohag University Active not recruiting No outcome recorded
Phase 0 NCT07108465 Comparator Jul → Sep 2025 overdue impacted teeth, multiple Henrique Tedesco Recruiting No outcome recorded
Phase 0 NCT06617949 Comparator Jan 2025 → Dec 2027 expected substance-related disorder Medical College of Wisconsin Recruiting No outcome recorded
Phase 0 NCT06680167 Comparator Oct 2024 → Nov 2025 Sohag University Completed No outcome recorded
Phase 0 NCT05824338 Comparator Aug 2024 → Jul 2025 overdue Fraser Health Recruiting No outcome recorded
Phase 153 trials
Phase 1 NCT07380139 Comparator Feb → Dec 2026 expected Ain Shams University Enrolling by invitation No outcome recorded
Phase 1 NCT07332130 Comparator Dec 2025 → Jan 2026 overdue Minia University Hospital Not yet recruiting No outcome recorded
Phase 1 NCT07182110 Comparator Aug 2025 → Aug 2026 overdue gallbladder disorder Makassed General Hospital Active not recruiting No outcome recorded
Phase 1 NCT07049835 Comparator Jun 2025 → Jul 2026 overdue Makassed General Hospital Active not recruiting No outcome recorded
Phase 1 NCT07023991 Background May → Aug 2025 overdue Ain Shams University Enrolling by invitation No outcome recorded
Phase 1/222 trials
Phase 1/2 NCT07482709 Comparator Nov 2025 → Mar 2026 overdue Liaquat National Hospital & Medical College Recruiting No outcome recorded
Phase 1/2 NCT06382220 Comparator Apr → Jul 2024 Fayoum University Hospital Completed No outcome recorded
Phase 1/2 NCT06362915 Comparator Jan → Jul 2024 Ain Shams University Unknown No outcome recorded
Phase 1/2 NCT05590234 Comparator Nov 2022 → Jul 2023 October 6 University Completed No outcome recorded
Phase 1/2 NCT05257941 Comparator Jan 2022 → Aug 2024 Indiana University Terminated No outcome recorded
Phase 2119 trials
Phase 2 NCT07616882 Comparator Apr → Sep 2027 expected Liaquat National Hospital & Medical College Not yet recruiting No outcome recorded
Phase 2 NCT07689162 Comparator Jul 2026 → Jun 2027 expected neuropathy, painful Washington University School of Medicine Not yet recruiting No outcome recorded
Phase 2 NCT07465185 Comparator Mar → Sep 2026 expected Benha University Recruiting No outcome recorded
Phase 2 NCT07574385 Comparator Mar → Aug 2026 overdue toe, misshapen Rebel Medicine Inc Recruiting No outcome recorded
Phase 2 NCT06529432 Comparator Mar → Nov 2026 expected Jiangsu HengRui Medicine Co., Ltd. Recruiting No outcome recorded
Show all 119 trials opens the full record — a long page
Phase 2/354 trials
Phase 2/3 NCT06956950 Comparator May → Oct 2025 overdue Tanta University Recruiting No outcome recorded
Phase 2/3 NCT05161637 Comparator Apr → Dec 2025 Taiwan Liposome Company Unknown No outcome recorded
Phase 2/3 NCT06662175 Background Nov 2024 → Jul 2025 overdue Lady Reading Hospital, Pakistan Not yet recruiting No outcome recorded
Phase 2/3 NCT06559969 Comparator Sep 2024 → Dec 2026 expected University of Iowa Recruiting No outcome recorded
Phase 2/3 NCT06350981 Comparator Apr 2024 → Jan 2026 overdue substance-related disorder Foundation for Orthopaedic Research and Education Enrolling by invitation No outcome recorded
Phase 3104 trials
Phase 3 NCT07663435 Comparator Jul → Dec 2026 expected Ain Shams University Not yet recruiting No outcome recorded
Phase 3 NCT07665762 Comparator Jun 2026 → Sep 2028 expected The University of Hong Kong Not yet recruiting No outcome recorded
Phase 3 NCT07573969 Comparator May 2026 → May 2027 expected Ain Shams University Recruiting No outcome recorded
Phase 3 NCT07467356 Comparator Mar → Aug 2026 overdue Benha University Recruiting No outcome recorded
Phase 3 NCT07326397 Background Feb 2026 → Nov 2027 expected Assiut University Not yet recruiting No outcome recorded
Phase 4467 trials
Phase 4 NCT07614802 Background Aug 2026 → Aug 2027 expected Duke University Not yet recruiting No outcome recorded
Phase 4 NCT07644923 Background Aug 2026 → Aug 2028 expected NYU Langone Health Not yet recruiting No outcome recorded
Phase 4 NCT07632820 Background Aug 2026 → Aug 2029 expected Mayo Clinic Recruiting No outcome recorded
Phase 4 NCT07097493 Comparator Aug → Dec 2026 expected osteoarthritis, knee Wake Forest University Health Sciences Not yet recruiting No outcome recorded
Phase 4 NCT07430085 Comparator Jul 2026 → Jan 2028 expected osteoarthritis, knee Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) Not yet recruiting No outcome recorded
Show all 467 trials opens the full record — a long page
Phase not applicable517 trials
NCT05785377 Comparator Dec 2027 → Jul 2029 expected Mansoura University Not yet recruiting No outcome recorded
NCT07624890 Comparator Dec 2026 expected neuroma Ukrainian Society of Regional Anesthesia and Pain Therapy Not yet recruiting No outcome recorded
NCT07667439 Comparator Jul 2026 → Feb 2027 expected Second Affiliated Hospital, School of Medicine, Zhejiang University Not yet recruiting No outcome recorded
NCT07429019 Comparator Jul 2026 → Jul 2027 expected chronic pain syndrome Hadassah Medical Organization Not yet recruiting No outcome recorded
NCT07654556 Comparator Jul 2026 → Mar 2027 expected Cairo University Not yet recruiting No outcome recorded
Show all 517 trials opens the full record — a long page

Evidence & citations 93 cited values

Every value below carries the sentence it was read from. 2,212 sources stand behind the page.

FieldValueCited text
Known as bupivacaine “patients whose labor analgesia is maintained using PIEB with low-volume bolus (6.25 mL) of a higher local anesthetic concentration solution (0.1% bupivacaine with fentanyl 2.0...” NCT03553576
1899

“The procedure will be completed by applying the first injection to the femoral triangle (10 ml of local anesthetic solution), the second injection to the subsartorial region...” NCT05566561

“Suprascapular nerve block with Bipuvacaine: a 50mm 22G needle (Stimuplex, BBraun) was introduced up to the suprascapular fossa, guided by ultrasound, and the location was...” NCT05778422

“After the surgery: 10 ml 0.25% bupivacaine through epidural catheters before extubation and continuous infusion of 0,1% bupivacaine and 1 µg/ml fentanyl 5 ml/h with...” NCT02622893

“For patient undergoing total knee replacement arthroplasty, patients injected intrathecally with bupivacaine 8 mg were compared with those with bupivacaine 8 mg with 25 mcg of...” NCT01261078

“A formulation of bupivacaine, given as a single injection after surgery, that could provide adequate, continuous, and extended pain relief would greatly simplify postoperative...” NCT00485667

“The purpose of this study is to evaluate the use of an injectable combination of bupivacaine and meloxicam (Zynrelef) vs injectable liposomal bupivacaine (Exparel), two...” NCT06349772

“Preservative free 0.5% Hyperbaric bupivacaine (AstraZeneca) 5mg + 25mcg fentanyl for the initial dose will be followed by top up doses of 2.5 mg boluses of 0.5% Hyperbaric...” NCT05897151

“USG with a 25G needle, Bupivacaine 0.5% 30ml with 4mg preservative free dexamethasone divided as follows into the following 5 nerves: Posterior Tibial nerve (10ml), Saphenous...” NCT05368012

“The purpose of this study is to determine whether an injection of a local anesthetic (Bupivacaine with epinephrine) in the vaginal cuff prior to closure would result in less...” NCT06719180

“Under steady state 0.2 ml kg(-1) and after 10 min 0.4 ml kg(-1) of one of the following three test solutions was administered i.v.: bupivacaine 0.125% (Group 1), bupivacaine...” PMID 19915187 Jan 2010

“Exparel (bupivacaine liposome injectable suspension) is a liposome injection of bupivacaine, an amide-type local anesthetic, indicated (bupivacaine liposome injectable...” NCT03769714

“To evaluate if an injection in the retropubic space with a local acting anesthetic, Marcaine, (bupivacaine) at the time of mid-urethral sling placement will improve patients'...” NCT00746863

“standard clinical practice for TAP blocks typically involves local anesthetics like bupivacaine, which, when administered in the appropriate plane, has been shown to reduce...” NCT06925152

“Bladder instillation mixture of heparin (10,000 units), 2% viscous lidocaine (10 mL), 8.4% sodium bicarbonate (15 mL of 1 mEq/mL), 0.5% bupivacaine (10 mL of 5 mg/mL) plus...” NCT03463915

“The blockage of the saphenous nerve in the adductor canal will be performed with 30 mL of local anesthetic (0.25% bupivacaine) solution with a 22 gauge 5-8 cm long block needle...” NCT05742958

“This is a prospective, single-institution, parallel-group, single-blinded, randomized-controlled, two-arm, effectiveness study comparing bupivacaine liposomal injectable...” NCT02111746

“At the onset of late stage breakthrough pain one arm of patients will receive a mixture of 75 mcg clonidine and 10 mg bupivacaine in 8 ml of volume and the second group will...” NCT00691795

“The "Control Arm" will receive an adductor canal catheter through which they will receive a 20 ml bolus of 0.25% bupivacaine with 1:400,000 epinephrine followed by an adductor...” NCT02991404

“An injection of 2 ml of hyperbaric bupivacaine will be injected into the subarachnoid space through 25 gauge spinal needle, then 15ml 0.5% bupivacaine, 25 micrograms of...” NCT02128451

“Participants randomized to the experimental arm will receive a bilateral rectus sheath block which is additional to the standard of care (infiltration of 5mg (2mL) 0.25%...” NCT04717193

“patients received 50 ml of isotonic aqueous solution (PH 7.45) of tramadol 150mg mixed with bupivacaine 0.25% immediately before creation of a pneumoperitoneum and placement of...” NCT04813016

“ZYNRELEF® is an extended-release, fixed-ratio combination product that contains bupivacaine (a local anesthetic as the free base) and low-dose meloxicam (an NSAID) incorporated...” NCT05863221

“we propose that by injecting the uterosacral ligaments and thus the uterine nerve during robotic assisted hysterectomies with Marcaine (Bupivacaine 0.5% with epinephrine...” NCT02230735

“In both M group and B group, preemptive US guided Subcostal TAP block (Toshiba Xario, Japan) was performed on both sides using 20 ml volume (0.25 Bupivacaine in B group or 0.25...” NCT02533284

“Patients in this group will receive the standard spinal anesthetic consisting of hyperbaric bupivacaine 0.5% (15 mg) combined with an equivalent volume of normal saline (0.9%...” NCT07327879

“The anesthesiologist will direct a 22G, 80 mm needle toward the transversus abdominis fascia and inject 25 mL of 0.25% bupivacaine between the rectus abdominis and transversus...” NCT06584695

“In addition either caudal anesthetic block (0.25% bupivacaine 1 ml/kg to a maximum of 10 ml) or dorsal penile block (bupivacaine without epinephrine 10-20 ml/kg) will be...” NCT02512887

“Based on a randomized allocation, patients will receive either a caudal anesthetic block (0.25% bupivacaine, 1 ml/kg, up to a maximum of 10 ml) or a dorsal penile block...” NCT06417060

“Parallel Study to Evaluate the Pharmacokinetics, Dose Proportionality, Safety and Tolerability of GTX-101 (Bupivacaine Hydrochloride Metered Dose Spray) and Subcutaneous...” NCT05517486

“Patients were infiltrated with 2 milliliters of local corticosteroid (Methyl prednisolone acetate 80mg) mixed with 1 milliliters 0.5% Bupivacaine, at the lateral epicondyle...” NCT00947765

“Intra-Articular Injection is an injection of 3-6 milliliter (mL) hyaluronic acid (HA) mixed with 1 milliliter (mL) depo methylprednisolone (a steroid) and 2 mL 0.5% bupivacaine...” NCT04504812

“DepoFoam® bupivacaine (Pacira Pharmaceuticals, Inc., San Diego, CA, USA), an extended-release liposomal bupivacaine-based analgesic, was compared with placebo for the...” PMID 21842428 Aug 2011

“This study is perfored to investigate the efficacy of preoperative lidocaine spray and lidocaine-bupivacaine mixture-soaked nasal packing for acute postoperative pain after...” NCT03733275

“DISCUSSION: A 10 mL 0.15% bupivacaine bolus in continuous adductor canal block offers comparable average knee-pain relief 6 and 12 hours after total knee arthroplasty to a...” PMID 40393775 May 2025

“In the epidural catheter a bolus of 8 ml bupivacaine 2,5 mg/ml is given and an infusion of isotonic potassium chloride, 4-7 ml/t depending on patient height is started and runs...” NCT01760174

“Liposomal bupivacaine, a multivesicular formulation engineered to provide sustained and controlled release of bupivacaine, has been developed to prolong analgesic duration and...” NCT07196631

“an ultrasound guided erector spinae plane catheter with initial bolus of 30 mL of 0.25% bupivacaine followed by infusion of 0.2% ropivacaine at 10 mL per hour via programmed...” NCT06347874

“Under ultrasound guidance, the transverse process was identified, and 30 ml of 0.25% bupivacaine was injected into the fascial plane between the erector spinae muscle and the...” NCT07454304

“In the EVE group, 1 mL of a mixture containing a combination of 10 µg fentanyl and 0.25% isobaric bupivacaine was injected into the intrathecal region via a 25-G 120 mm...” PMID 40068075 Mar 2025

“Intercostal nerve block using single total administration of 20 mL EXPAREL (bupivacaine liposome injectable suspension) 266 mg (approximately 88 mg \[6.6 mL\] to each of three...” NCT01802411

“Subjects randomized to the PVB arm will have an ultrasound-guided paravertebral block performed pre-operatively in the anesthesia block room with 20ml of a ropivacaine /...” NCT03471442

“Patients will receive bilateral deep parasternal plane block using, 1mg/kg of 0.25% bupivacaine on each side under ultrasound guidance. The total dose of bupivacaine amounting...” NCT06873906

“Patients will receive a 5mL injection comprised of 4.5mL 1% bupivacaine and 0.5mL of dexamethasone (10mg/mL) directed towards the sphenopalatine ganglion on each side (5 mL on...” NCT04331938

“Thoracic paravertebral block (TPVB) is being performed by injecting 5 mL of Bupivacaine 0.5% to 4 consecutive level of paravertebral spaces between T4 and T8 by using landmark technique” NCT02302586

“The control group received postoperative epidural morphine 0.4 mg/ml four times a day, epidural bupivacaine 2.5 mg/ml, 3-4 ml on request for 75 hours and a 7 day rehabilitation program.” NCT01513564

“Patients receiving the IA corticosteroid will be injected 3mL of 0.5% Bupivacaine and 2mL of 80mg Depo Medrol in a 10cc syringe, using an aseptic technique into the suprapatellar pouch.” NCT01923909

“The intervention involves injection of local anesthetic (0.25% bupivacaine with 1:200,000 epinephrine) under direct vision in the serratus anterior muscle plane at the end of surgery.” NCT02893384

“A 5 mL injection of 0.5% bupivacaine will be administered into the trans-obturator/levator ani sling insertion site at the end of the TVT or TVT-O procedure, prior to wound closure.” NCT07429019

“Subjects in the Experimental Group will received a 2 mL injection consisting of 1 mL of 0.5% bupivacaine (5 mg bupivacaine-HCL) and 1 mL Kenalog-40 (40 mg triamcinolone acetonide).” NCT05178485

“20 mL of local anesthetic solution (10 mL of 0.5% bupivacaine and 10 mL of 2% lidocaine) was injected bilaterally into the erector spinae plane at the T7-T8 level before incision.” NCT07057934

“Intrathecal 10 mg Heavy Marcaine, 200 mcg Morphine + High volume local anesthesia infiltration Bupivacaine 5mg/ml + adrenaline 5 mcg/ml 3mg/kg IBW diluted with 100cc Normal Saline” NCT03176758

“Participants will be randomly allocated to receive either an ultrasound-guided femoral nerve block with 20 mL of 0.5% bupivacaine or intravenous fentanyl at a dose of 1 mcg/kg.” NCT06862154

“Group A will receive one intra-articular injection of 2 ml of solution containing 1ml of 10mg/ml Triamcinolone suspended in 1 ml of 0.5% Bupivacaine solution per affected joint” NCT01920373

“Patients will receive bilateral ultrasound-guided intramuscular quadratus lumborum block with an injection of 0.4 ml/kg bupivacaine 0.25% after induction of general anesthesia.” NCT06889987

“Intrathecal hyperbaric bupivacaine (0.5%) and a mixture of propofol (1-2 mg/kg) and fentanyl (50-100 μg/kg) were used as induction agents in the SA and GA groups, respectively” PMID 39740955 Apr 2026

“The purpose of this study is to determine whether injection of bupivacaine into the TAP is effective in the treatment of post operative pain after laparoscopic gastric bypass” NCT01308554

“G1 patients received 1 mg (1 ml) morphine diluted in 9 ml saline by the intra-articular route, and G2 patients received 25 mg (10 ml) 0.25% bupivacaine without epinephrine.” NCT00636415

“Standard thoracic epidural analgesia mixture (2 mg/ ml bupivacaine, 2 µg/ ml fentanyl and 2 µg/ ml adrenalin) with an infusion of 6-10 ml/hour until day 2 postoperatively.” NCT04025606

“Ultrasound guided supra-inguinal fascia iliaca block with 0.25% bupivacaine 40 ml and 0.5% Iso/Hyperbaric bupivacaine 2-3 ml without spinal morphine for spinal anesthesia” NCT04104204

“After mesh placement, a long-acting local anesthetic (bupivacaine hydrochloride, 0.50%) or placebo (0.9% normal saline) was injected between the mesh and the peritoneum.” PMID 26154700 Sep 2015

“Intrathecal preservative free morphine (duramorph) 200 mcg with 7.5mg of hyperbaric bupivacaine placed by a spinal needle prior to induction of general anesthesia (n=71)” NCT06593665

“Up to 2.5 mg/kg bupivacaine administered by caudal or subarachnoid routes or both caudal and subarachnoid or subarachnoid and ilioinguinal nerve blockade. Single shot.” NCT00756600

“Multimodal local injection of bupivacaine (Marcaine), morphine sulfate (Duramorph), ketorolac (Toradol) given at the fracture site at the time of hip fracture surgery” PMID 37199438 Sep 2023

Bupivacaine Liposome Versus Bupivacaine for Ultrasound-Guided Suprascapular Nerve Combined With Axillary Nerve Block in Analgesia After Arthroscopic Shoulder Surgery” NCT07410182

“TAP Block in the experimental arm will be performed with 20 mL (266mg) of liposomal bupivacaine with 25 mL (5 mg/mL) of bupivacaine diluted in 55 mL of normal saline” NCT04781075

“Hydromorphone will be received intravenously using a patient controlled administration pump, as well as patient will have a continuous bupivacaine epidural infusion” NCT06559969

“A predetermined small dose of hyperbaric bupivacaine (Marcaine Spinal Heavy; Astra Zeneca, Lund, Sweden) which was prepared in1 mL tuberculin syringe was injected.” NCT02299167

“EUS procedure with injection of 10 ml Bupivacaine 0.5% and 40 mg of Triamcinolone in the celiac plexus after administration of intravenous (IV) antibioprophylaxis” NCT01318590

“The investigators have previously utilized the On-Q® pain ball to obtain local control by continuous delivery of bupivacaine to pain fibers at the incision site.” NCT02142829

“Patients will receive either 3 XaraColl Bupivacaine Implants each containing 100 mg of bupivacaine hydrochloride, for a 300 mg total dose; or 3 placebo-sponges.” NCT02523599

“The medication used for the block are clonidine 100 mcg, Decadron PF 5mg and 0.25% bupivacaine 5 mL. This medication will be administered once during the block.” NCT04445337

“The specific aim of this study is to evaluate plasma concentration of bupivacaine after intraoperative intercostal injections of 266 mg of liposomal bupivacaine” NCT03737292

“Chemical ablation is performed by injection of 10 mL of 0.25% bupivacaine, followed by 10 mL of 98% dehydrated alcohol using a 22G FNA needle (Cook and Olympus)” NCT04801082

Bupivacaine, a long-acting local anesthetic, is hypothesized to reduce postoperative pain when instilled into the peritoneal cavity at the end of the procedure.” NCT07098429

“The knee joint capsule, periarticular and subcutaneous tissues will be infiltrated with 150 mg of bupivacaine, 0.3 mg of epinephrine and 90 ml of normal saline.” NCT04258241

“Patients received ultrasound guided bilateral single shot erector spinae pane block (ESPB) at Th10 level with 20 mL 0.25% bupivacaine after the end of surgery.” NCT06422182

“Group F (fentanyl group):will receive intrathecal 1.5 ml hyperbaric bupivacaine 0.5% and 0.5 ml (25 mcg) Fentanyl and 1 ml glucose 5% with total volume of 3ml.” NCT07114263

“Patients will receive an intercostal nerve block with a mixture of liposomal bupivacaine and bupivacaine hydrochloride immediately after lung transplantation.” NCT07641647

“Group A will receive 0.07 mg/cm of 0.5% Hyperbaric Bupivacaine in conjunction with 2 mg (0.5 ml) of preservative-free Dexamethasone administered intrathecally” NCT07363941

“i.e., a programmed intermittent bolus of 10 ml of 0.1% bupivacaine and 2 μg/ml fentanyl every hour until the completion of labor and suturing of the incision.” NCT06580327

“the prilocaine group underwent spinal anaesthesia with 60 mg intrathecal prilocaine; and the bupivacaine group received 12.5 mg intrathecal heavy bupivacaine.” PMID 33428221 Jan 2021

Bupivacaine: Patients will receive 10 ml of 0.5% bupivacaine + 10 ml of 1% lidocaine with 1:100,000 epinephrine (buffered 10:1 with 8.4% sodium bicarbonate).” NCT05697276

“Our study will compare Exparel (bupivacaine liposome) with Ropivacaine continuous infusion for post-operative pain scores in total shoulder surgery patients.” NCT03739021

“ultrasound guided TAP block, 133 mg of liposomal bupivacaine and 15 mL of 0.25% bupivacaine deposited into the TAP on each side for a total of two injections” NCT06213454

“0.25% bupivacaine, with 10 mL (25 mg) delivered to perform a field block of the soft tissue and subfascial plane at the initiation of the surgical procedure.” NCT02933814

“Solutions contain either 0.3% Ropivacaine, 1% Procaine, 0.5% Lidocaine, 0.25% Bupivacaine, or a mixture of 0.25% Bupivacaine and 2% Lidocaine in a 9:1 ratio.” NCT06617065

“3ml intrathecal starting at a mass of 10 µmol bupivacaine, levobupivacaine or ropivacaine by a combined spinal-epidural analgesia technique (groups A, B, C).” NCT01201213

“30 mL of 0.25% Bupivacaine will be injected into the plane between the Serratus Posterior Superior muscle and the intercostal muscles at the scapular level.” NCT07436806

“Liposomal bupivacaine, trade name Exparel, was recently introduced as an alternative to drugs such as bupivacaine, but boasting a longer duration of action.” NCT06139666

“Two cc containing 40 mg of triamcinolone acetonide with 5 mg bupivacaine will be infused into the upper joint space after the TMJ arthrocentesis procedure.” NCT04731233

“will include 30 patients: each one will receive 2.5 mg/kg of 0.25% bupivacaine diluted in a 20 mL syringe of normal saline, 10 minutes before skin incision” NCT04838379

“Phase 3 Study Comparing Transversus Abdominis Plane Block After Caesarian Section Usin Bupivacaine 0.5% vs. Bupivacaine 0.25% vs. Placebo (Normal Saline).” NCT01986049

“Therefore, we designed a prospective randomized controlled trial to compare the analgesic efficacy of combining magnesium sulfate with bupivacaine in QLB.” NCT06301789

“All patients in the study group will receive bilateral pudendal nerve block at the end of surgery, with help of landmark technique, using 0.5% bupivacaineNCT05022160

“Betamethasone Sodium Phosphate/Acetate 5.7 mg/ml Injectable is a particulate corticosteroid and is used with the local anaesthetic bupivacaine 0.5% (1ml).” NCT03240783

“The ITM group received morphine, clonidine and bupivacaine intrathecally; the EDA group had an epidural infusion of bupivacaine, adrenalin and fentanyl.” PMID 30837253 Mar 2019

“Cluneal nerve Block 0.25% bupivacaine 20ml Pericapsular Nerve group block 0.25% Bupivacaine 20ml Lateral femoral cutaneous Block 0.25% bupivacaine 10ml” NCT04426058

“hyperbaric bupivacaine 0.5% 1.8 ml mixed with intrathecal morphine 100 µg (M100), intrathecal morphine 50 µg (M50), or intrathecal fentanyl 25 µg (F25)” PMID 42332552 Jun 2026

“A single vial of liposomal bupivacaine (20 mL 1.3%, 13.3mg/mL, 266 mg) will be diluted in 50cc bupivacaine to a volume of 60cc prior to administration.” NCT04005859

“Comparative Study Between Dexmedetomidine and Fentanyl as an Adjuvant to Intraarticular Bupivacaine for Postoperative Analgesia after Knee Arthroscopy.” PMID 34704709 Nov 2021

“10 mg 0.5% bupivacaine + 20 mcg Fentanyl injection will be applied using a 26 Gauge pencil point needle through the L3-L4 or L4-L5 intervertebral space” NCT05965544

“spinal anesthesia with 10 mg hyperbaric Bupivacaïne 0,5% + 2,5 µ Sufentanyl + 100 µ of intrathecal Morphine+ infiltration catheter with saline 5 ml/h” NCT02711072

“ultrasound guided Retrolaminar Block (RLB) with 20 ml (0.5% Bupivacaine) plus 5 mic/ml Adrenaline (1:200,000) at the level of T4 of the surgical side” NCT04531215

“Each study arm will receive their respective formulation of local anesthetic, either standard bupivacaine or liposomal bupivacaine upon randomization” NCT03182933

“a total of 4 mL of local anesthetic solution consisting of 2 mL of 0.5% bupivacaine and 2 mL of 2% lidocaine (Aritmal) will be injected on each side.” NCT07608861

“Ganglion Impar Block using Triamcinolone Acetate (40 mg) and Bupivacaine (0.25%) administered with a 22G Spinal Needle under Fluoroscopic Guidance).” NCT06754033

“Liposomal bupivacaine is a novel formulation of bupivacaine designed for slow diffusion of a single dose of local anesthetic over a 72-hour period.” PMID 27159290 Apr 2016

“Use of ropivacaine 0.5% with 1:400,000 epinephrine in the adductor canal along with a spinal anesthesia of 3ml 0.5% preservative-free bupivacaine.” NCT02411149

Bupivacaine 2% - a local anesthetic that binds voltage-gated sodium channels and blocks sodium influx into nerve cells preventing depolarization.” NCT02485145

“Each patients group will recieve a type of block by injecting 20 ml of 0.25% bupivacaine on each side in patients undergoing open cholecystectomy” NCT06410911

“Patients will receive bilateral Ultrasound-guided Erector Spinae Plane Block with bupivacaine and dexamethasone 15 minutes before skin incision” NCT05105997

“A single injection of 30 ml of bupivacaine 0.25% will be applied into the interfacial plane between the rhomboid major and intercostal muscles.” NCT05452369

“All patients received 8 ml of LAM which consisted of: 6 ml of ml of bupivacaine 0.5%, 1 ml of hyaluronidase containing 150 IU, 1 ml of additive” NCT03824665

“5ml 0.25% Bupivacaine ve 50mcg Dexmetedomidin (diluted to 5ml with normal saline) intraarticularly at the end of surgery (total volume: 10 ml)” NCT03479216

“intraperitoneal instillation of the study drug(40 ml bupivacaine 0.25% + 1 µg/kg dexmedetomidine diluted in 5 ml normal saline) will be done” NCT04525274

“Control group to receive 10cc of 0.5% bupivacaine with 1:50,000 epinephrine at the completion of the procedure per typical standard of care.” NCT06499181

“In the intrathecal morphine group, 100 micrograms of morphine (0.1 mL) will be added to the 12 mg of intrathecally administered bupivacaine.” NCT06612424

“Group FENT, consisting of 29 patients, underwent a saddle block with hyperbaric bupivacaine (2.5 ml) combined with fentanyl (0.5 ml; 25 μg).” NCT06216197

“30 mL of .25% bupivacaine with 2.5mcg/mL epinephrine will be injected on both sides of the mid-abdomen posterior to the mid-axillary line.” NCT03794882

“Patients will receive16 ml bupivacaine 0025% will be administered, and4 ml of this solution will be placed at each of the 4 target nerves.” NCT05269095

“Patients will receive continuous epidural analgesia using bupivacaine 0.125% in conjunction with fentanyl 2 ug/ml at a rate of 8-15 ml/hr” NCT04541719

“Group D: patients will receive 3 mL volume of 0.5% hyperbaric bupivacaine and 4 µg dexmedetomidine in 0.5 mL of normal saline intrathecal” NCT07035223

“Intervention group will receive 30 ml of a 50/50 mixture of isobaric bupivacaine 0.5% and lidocaine 1%, containing 8 mg of dexamethasone.” NCT07313553

“The first group received 0.5% bupivacaine, the second group received 0.375% bupivacaine, and the third group received 0.25% bupivacaine.” PMID 39355572 Jun 2024

“20cc of 2% lidocaine with 1:200,000 epinephrine + 20 cc of 0.5% bupivacaine with 1:300,000 epinephrine will be injected around the nerve” NCT02280291

“the first group (dexmedetomidine5 μg group) will be received 2mL (10 mg) of heavy bupivacaine plus 5 μg of dexmedetomidine intrathecally” NCT05351489

“Two 20 mL syringes were prepared after preparing a local anesthetic concentration of 1.5 mg/kg of 0.5% bupivacaine to 40 mL with saline.” NCT02645903

“the participant will receive 5 ml bupivacaine infiltration to each trocar site (total of 25 ml 0.5 %) at the beginning of the operation.” NCT06377605

“The following drugs will be used for this procedure: 80mg/2ml triamcinolone acetonide (sinakort-A) and 1 mL 0.5% bupivacaine (marcaine)” NCT04212949

“Epidural medication will be the same in both groups and will consist of bupivacaine 0,05% with fentanyl 2 µg/mL and adrenaline 2 µg/mL.” NCT05534945

“A single 14 mL dose of HTX-011 containing 400 mg bupivacaine and 12 mg meloxicam will be applied intraoperatively to the surgical site.” NCT07216586

“Patient will receive ultrasound guided regional anesthesia with bupivacaine and intravenous patient controlled analgesia with tramadol” NCT04457986

“Patients received superficial cervical plexus block with 1 ml of normal saline with 7ml bupivacaine 0.25% per side without adjuvants.” NCT07057739

“Patients will receive mixture of bupivacaine 0.5% (4.5 ml) + lidocaine 2% (4.5 ml) + dexmedetomidine 50 μg (1 ml) in peribulbar block” NCT05692167

“The local anesthetic solution is injected with a dose of 0.5% bupivacaine (0.08 ml/kg), in addition to dexmedetomedine (0.5 μg /kg)” NCT04485273

“0.5% hyperbaric bupivacaine will be administered intrathecally for spinal anesthesia in patients undergoing cystoscopic procedures.” NCT07590544

“Magnesium Sulphate (Group M): 50 mg magnesium sulphate added to 12.5 mg of 0.5% hyperbaric bupivacaine, administered intrathecally.” NCT07113782

“The mean ± standard deviation maximum observed plasma concentration (C max) of bupivacaine after a single dose was 129 ± 47 ng/mL.” PMID 28120158 Mar 2017

“Patients will be anesthetized with ultrasound-guided pericapsular nerve group block (PENG block) using 20 ml of 0.25% bupivacaine.” NCT06034873

“2 mg/kg bupivacaine 0.5% and 1 ug/kg of dexamedetomidine diluted in normal saline 0.9 % will instilled into the peritoneal cavity” NCT02820610

“Marcaine hydrochloride (bupivacaine) without epinephrine 0.5% was chosen for this study because this was used in previous studies” NCT06842771

“Transversus Abdominus Plane (TAP) block: Bupivacaine (30 ml of 0.25%)is injected between internal oblique and transveralis facia.” NCT02632136

“Patients will receive general anesthesia (GA) with ultrasound guided serratus anterior plane block 0.5 ml/kg 0.25% bupivacaine.” NCT06862518

“Exparel is a formulation of liposomal bupivacaine that is reported to allow local anesthesia for up to 72 hours post injection.” NCT02499159

“Trigger point injection with 25G needle on the shoulder before surgery(0.5% procaine, 0.25\~0.5% lidocaine, 0.125% bupivacaine)” NCT01845532

“Patients will receive 25 micrograms fentanyl ( after dilution with 2.5 ml CSF) in 20 seconds then 10 mg hyperbaric bupivacaine.” NCT02951806

“Drug: Hyperbaric Bupivacaine will be injected in the subarachnoid space with a dose of 8 to 12 mg adjusted according to height” NCT03849508

“using 20 ml bupivacaine 0.25% that will be injected for each side ensuring not to exceed the maximal 2 mg/kg bupivacaine dose.” NCT06870383

“Patients in this group will receive errector spine plane block with 30 ml bupivacaine 0.25% plus 1ml of 1µg/kg Dexmedetomidine” NCT04650737

“IPACK block with 20 mL of 0.25% Bupivacaine injected into the Interspace between the Popliteal Artery and Capsule of the Knee” NCT05286307

“%0.25 bupivacaine) will be performed Drug: Tramadol 400 mg tramadol, IV 4 mg/ mL tramadol solution into 100 mL normal saline” NCT07096765

“Subjects randomized to clonidine will receive a mixture of 100 micrograms clonidine and 12.5 mg bupivacaine 10 ml of volume.” NCT01846221

“Liposomal bupivacaine 266 mg (1.3% in 20 ml) will be diluted to 40 ml volume with 20 ml of preservative free normal saline.” NCT03737604

“The patients receive 20ml plain bupivacaine (0.5%) + 2 ml of Normal saline in adductor canal block after spinal anesthesia.” NCT04892420

“15 cc of Marcaine 0.5% (Bupivacaine 0.5%, 5mg/ml) will be administered into the wrist per the Surgeon's Standard practice.” NCT02052180

“all patients receive spinal anesthesia with a solution of 2 ml hyper-baric bupivacaine 0.5% (10 mg) and 3 μg of sufentanil” NCT07377630

“Following PCNL under general anesthesia, patients will receive 0.25% Bupivacaine ( Marcaine) local anesthetic infiltration” NCT04160936

“An injection of local anaesthetic (3 ml of 0.25% bupivacaine) will be administered around the trunk of the pudendal nerve.” NCT02502591

“Following confirmation of the correct position of the needle, 30 mL %0.25 bupivacaine will be administered for the block.” NCT07278050

bupivacaine 0.25% and dexmedetomidine 0.5 mcg/mL (total volume of 10 mL) by epidural-catheter bolus given preoperatively” NCT05069311

“Medications used during the procedure include 0.75% bupivacaine with or without 1 mg of preservative free dexamethasone.” NCT06621329

“It will consist of the following local anesthetics and adjuvants: Hypobaric Bupivacaine 0.5% 7.5 mg and Sufentanil 5 µg.” NCT06155903

“HTX-011 (bupivacaine and meloxicam in Biochronomerpolymer technology), an extended-release, dual-acting local anesthetic” PMID 31113830 May 2019

“The intervention group will receive bupivacaine injection guided by ultrasound at the location of the stellate ganglion.” NCT05656170

“Following this, the total volume of 40 ml of 0.25% bupivacaine will be instilled, creating a meniscus between the planes” NCT06721039

“30ml total volume of 0.25 plain bupivacaine 1.5mg/kg with lidocaine 1% 3mg/kg with 8mg dexamethasone in group A patients” NCT06131593

“Patients will receive ultrasound-guided rectus sheath block (20 ml bupivacaine 0.25%) bilaterally at the end of surgery.” NCT06837532

“will receive an ultrasound guided PENG block with 20 mL of 0.5% bupivacaine followed by cryoablation of the PENG nerves.” NCT06278987

“Intrathecal anesthesia is with bupivacaine 12.5-15.0 mg, morphine 0.2 mg and clonidine 30 µg (total volume (3.2-3.7 mL).” NCT01604382

“Post-operatively all patients will have an ultrasound-guided adductor canal block (ACB) with 30cc of 0.25% bupivacaine.” NCT05004636

“Patients will receive rectus sheath block (20 ml bilaterally, bupivacaine 0.25%) after induction of general anesthesia.” NCT06837506

Bupivacaine Hydrochloride (Brand Name: Marcaine, Sensorcaine) Dosage Form: Injection Dosage: 3 ml vial, 0.5% solution” NCT02571283

“Parasternal block with Bupivacaine 0.25% + Epinephrine 1:200,000 x 60cc + Dexamethasone 5mg and Dexmedetomidine 50mcg” NCT05191745

“The intercostal infiltration with 30 ml of 0.25% concentration of bupivacaine will be performed by the surgical team.” NCT05972122

“Injection of 3 mcg of dexmedetomidine and 12 mg of bupivacaine in the intrathecal space to provide spinal anesthesia.” NCT05099055

“1.5 mL of 0.5% bupivacaine will be will be injected bilaterally in the paraspinal musculature of the cervical spine.” NCT04109885

“Where the anticipated surgical duration is longer than 90 minutes, 2 mL 0.5% bupivacaine (10 mg) may be substituted.” NCT05444751

“5cc of 0.5% bupivacaine will be injected into both right and left occipital nerves using a 2.5 inch 25 gauge needle.” NCT03951649

“10mg morphine in 5ml normal saline + 10ml of 0.25% bupivacaine ( total volume 15 ml) were injected intra-articularly” NCT04790292

“At the end of the surgery patients receive 0.5mg/dose neostigmine +18ml 0.25%bupivacaine in a total volume of 20 ml.” NCT03248648

“Obturator nerve regional block involves the injection of a local anesthetic called bupivacaine into the upper thigh.” NCT03326999

“One side with Marcaine (Bupivacaine HCL) 0.5% 5 mg / mL Injection,opposite side without injection of any anesthetic.” NCT03479996

“In the D1 group, patients were administered 20 mL of 0.25% isobaric bupivacaine with 0.5 mcg/kg of dexmedetomidine.” NCT06703229

“Bilateral lateral Quadratus Lumborum block using 20 ml of 0.25% bupivacaine each injection as preemptive analgesia.” NCT03879980

“intra-vesical: DMSO 50% in 50 cc water for injection 10 cc heparin 5000 IU hydrocortisone 100 mg bupivacaine 0.125%” NCT01074567

“Recently, liposomal bupivacaine (LB) (Exparel) was approved for single shot interscalene administration by the FDA.” NCT03822182

“After confirming the block location, 10 ml of 0.25% concentration marcaine (bupivacaine) will be used (bilateral).” NCT06285773

“Group B: The patients will receive 20 ml of 0.5% bupivacaine plus 5 ml 0.9% normal saline with total volume 25 ml.” NCT04429893

“Injection with10 mls 0.5% bupivacaine hydrochloride and 20 mg of Depomedrol 40 mls saline (NaCl) around the tendon” NCT02417987

“Treatment patients will also be given liposomal bupivacaine (EXPAREL, Pacira Pharmaceuticals, Inc. San Diego, CA)” NCT03743194

“spinal anaesthesia with intrathecal bupivacaine 0.5% (17.5 mg if greater than 70 kg and 15 mg if less than 70 kg)” NCT01312415

“In the application, a 22G 10 cm needle is used in the form of 20 ml 0.25% bupivacaine + 2.0 μg/mL of epinephrine.” NCT05943080

“30mL of 0.5% bupivacaine with 100 mcg clonidine, 0.3 mg buprenorphine, and 4 mg dexamethasone will be injected.” NCT05824832

Bupivacaine is a potent local anesthetic with unique characteristics from the amide group of local anesthetics.” NCT06668220

“Participants will get a QL block using 30cc Bupivacaine bilaterally in quadratus lumborum muscle (60cc total).” NCT05979493

“Intraperitoneal infiltration of 20ml of 0.25% Bupivacaine will be done at the end of procedure by the surgeon.” NCT07409688

“Patients of this group will receive 25 mg bupivacaine 0.5%, plus 8 mg dexamethasone in a total volume of 10 ml” NCT04656821

“single dose (10ml) of liposomal bupivacaine (Exparel) mixed with saline (10 ml) will be injected in each side.” NCT02996227

“intrathecal bolus of 3ml bupivacaine 0.5% (15mg) plus 10 micrograms dexmedetomidine at 2-3 or 3-4 spinal level” NCT05262166

“10ml bolus: bupivacaine 0.1% + 25mcg fentanyl, followed by a solution of bupivacaine 0.083% + fentanyl 1mcg/ml” NCT04202887

“15 mL of 0.25% Bupivacaine block of the saphenous nerve injected under ultrasound guidance via adductor canal.” NCT06952556

“Epidural labour analgesia was initiated with 5µg sufentanyl along with 5 ml bupivacaine 0.1% as the test dose.” NCT03395600

“a bolus of 0.5 ml/Kg bupivacaine 0.25% in addition to 2ml normal saline will be injected then dexmedetomidine” NCT03885804

“1 ml (7 mg / ml) betamethasone and 4 ml of 0.5% bupivacaine will be given subacromial bursa-subdeltoid space.” NCT04186624

“a mixture of 10 ml bupivacaine 0.5% plus 20 ml lidocaine 2% with adrenaline 1:200,000 will be slowly injected” NCT02065947

“Ultrasound guided ESP block will perform with 15 ml bupivacaine+ 5 ml lidocaine at the T10 level bilaterally.” NCT04148729

“adductor canal block with continuous infusion of 0.25% bupivacaine 3.5 ml per hour for 2 days postoperatively” NCT05518513

“10 mg bupivacaine will be injected in the subarachnoid space, after spontaneous surge of cerebrospinal fluid” NCT03600454

“The local anesthetic used in all cases was a mixture of 10 ml of 2% xylocaine and 10 ml of 0.5% bupivacaine.” NCT07299877

“Dexmedetomidine 3 µg (n=27) or normal saline (n=27) intrathecally with 6 mg of 0.5% hyperbaric bupivacaine.” PMID 23727917 2013

“an injection of Exparel (bupivacaine liposome injectable suspension), 20cc of 1.3% Exparel, to total 100cc.” NCT02808728

Bupivacaine 0.3% \[or ropivacaine 0.5%\] infusions for 7 days via femoral and sciatic perineural catheters” NCT03461120

“A mixture of 0.5 ml /kg bupivacaine (0.25%), and 0.5µg/Kg dexmedetomidine and Epinephrine 5 microgram/ ml.” NCT03408184

“Patients will receive adjuvant dexmedetomidine (25mcg) and dexamethasone (5mg) in addition to bupivacaine.” NCT06658054

“Liposomal Bupivacaine (Exparel®) or the control injected into the transversus abdominis plane bilaterally.” NCT04655339

“Intrathecal (i.e. spinal) anesthesia with isobaric bupivacaine 15 mg administered intrathecally at L4-L5.” NCT01733472

“Dexamethasone 10mg or Depomedrol 40mg, together with Bupivacaine 0.25% (for 3-5mL total injectate volume)” NCT02103543

“patients will receive 0.25% Bupivacaine (0.3ml/Kg) with 1 μg/kg dexmedetomidine After general anaesthesia” NCT04926454

“Intra-operatively: Bupivacaine 0.5% with adrenaline Post-operatively: Ropivacaine 0.2% + sufentanil 1 ug” NCT01367418

“20 ml 0.25% Bupivacaine along with 0.5 Mcg/kg of Dexmedetomidine will be given in TAPP block bilaterally” NCT07508202

“A total of 30 ml of 0.25% bupivacaine was administered deep to erector spinae muscle (ESM) bilaterally.” NCT06721832

“Caudal block will be performed with 0.75ml/kg of 0.25% bupivacaine containing 1 mic/kg dexmedetomidine.” NCT05233683

“The regimen consists of Bupivacaine 0.375% with the adjuvant Dexmedetomidine at a dose of 0.5 mcg/kgbw.” NCT07274670

“20 mL Liposomal bupivacaine (Exparel, 266 mg) will be administered in the popliteal and saphenous block” NCT06465992

“The analgesic effect of Two different doses of dexmedetomidine as adjuvent to bupivacaine in tap block” NCT06624319

“injection of bupivacaine 0.25%, dexmedetomidine 1 μg/kg (precedex 100mcg/ml), and adrenaline 1:200,000” NCT06490614

“intraarticular knee injection of betamethasone and bupivacaine 0.5% (dose is determined by joint size)” NCT04859764

“7.5 mg Bupivacaine hydrochloride (0.5% heavy Marcaine) will be used on spinal anesthesia. (each group)” NCT06293404

“A 6ml solution of 4ml 0.25% Bupivacaine, 1ml 40mg Kenalog, and 1ml 4mg Dexamethasone will be prepared.” NCT01688362

“Mixture of 50 mL of 0.25% Bupivacaine with epinephrine, 40 mL of sterile saline and 20 mL of Exparel®.” NCT02369523

“A solution containing fentanyl 2 mcg/mL and bupivacaine 0.625 mg/mL at an infusion rate of 0.5 ml/hr.” NCT07091123

“infiltration of the hip joint with hyaluronic acid, with a corticosteroid or with 0.125% bupivacaine.” PMID 21080920 Nov 2010

bupivacaine 15 mg 0.5% plus 2 mL normal saline containing 300 international units (IU) hyaluronidase.” NCT05344495

“A Randomized Controlled Trial of Liposomal Bupivacaine Parasternal Intercostal Block for Sternotomy.” PMID 30170012 Aug 2018

“Infiltration of surgical wounds with local anaesthetic at the end of surgery, Bupivacaine 1-2mg/kg.” NCT03859102

“12.5 mg ofhyperbaric bupivacaine (2.5 mL 0.5%) and 15 μg of fentanyl will be injected intrathecally” NCT07514130

Bupivacaine, Dexamethasone, Epinephrine for hernia patients receiving abdominal wall reconstruction” NCT07518238

“Intrathecal injection of 100 µg morphine plus 20 mg hyperbaric bupivacaine (in spinal anesthesia).” NCT06882369

“a mixture of 0.5 % bupivacaine (10 ml) and 2 % lidocaine (10 ml) will be injected into the muscle” NCT06462573

“The LA used for the blocks will be a 0.5% bupivacaine HCL, not to exceed 2.5mg/kg or up to 150mg.” NCT03731221

“Rectus Sheath Block: Total 60mL: (20mL 1.3% LB + 30mL 0.25% bupivacaine + 10mL NS. 30mL per side)” NCT05972018

“will have PENG block with 2mg magnesium sulphate 10% as an adjuvant to 20mg of bupivacaine 0.25%” NCT06180031

“Patients in this arm will receive an injection of 20cc of injectable 0.25% bupivacaine solution.” NCT05898087

“An injection of 1-2 ml bupivacaine 0.5% will be placed around the affected branch of the neuroma” NCT05695339

“Intraoperative periarticular injection of 30 mL of a 0.25% solution bupivacaine with epinephrine” NCT03119038

“Group H will receive 10 ml 0.25 % bupivacaine he technique will be repeated on the opposite side” NCT06621836

“dexamethasone 8mg, methylprednisolone 80mg and bupivacaine 5ml 0.25%, intra articular injection” NCT07489521

“Admixture bupivacaine 0.5 % 10 cc with Bupivacaine Liposome Injectable Suspension 10cc total 20” NCT06274008

Bupivacaine 0.5% administered after ablation as part of the post-procedural injection mixture.” NCT07475689

“Patients received bilateral ultrasound-guided ESPB using 20 mL bupivacaine 0.25% on each side.” NCT06695858

“standard of care medication-bupivacaine HCl 0.25% (2.5 mg/mL) with epinephrine (5 mcg/mL) i.m.” NCT03420638

Bupivacaine should reduce postoperative pain but it has relatively shorter duration of action.” NCT02969187

“The injection contained 150mg bupivacaine (3mg/mL), 60mg ketorolac(1.2mg/mL) and 1mg morphine.” NCT06630520

“0.5% bupivacaine with 1:200,000 epinephrine as the local anesthetic for Group 1 Experimental.” NCT03243032

“SGB) with bupivacaine, a local anesthetic, is an effective and safe non-hormonal intervention” NCT02907983

“After the block location is confirmed, 30 ml of 0.25% concentration bupivacaine will be used.” NCT05972083

“giving the longer-acting local anesthetic liposomal bupivacaine prior to closing the sternum” NCT04585867

“Femoral nerve block delivered via indwelling femoral nerve catheter with 0.125% bupivacaine.” NCT02341079

“Group LWI+IPLA will given 30 ml %0,5 bupivacaine+%2 lidocaine infiltration and instillation” NCT05405049

“Injection with 10 mls 0.5% bupivacaine hydrochloride and • 40 ml saline around the tendon.” NCT02839577

bupivacaine local anaesthetic bupivacaine 5 mg /ml, adrenaline 5 µg/ml maximum dosage 10 ml” NCT00805298

“20 milliliter (mL) EXPAREL with 20mL bupivacaine hydrochloride (HCL) 0.5% will be expanded.” NCT06619340

“Parasternal block group, bilateral parasternal block was performed using 0.25% bupivacaine.” NCT06893601

“consists of patients receiving Serratus anterior plane block using Bupivacaine + Ketamine.” NCT05802979

“Standard single-shot anesthesia consists of bupivacaine 0.25% with epinephrine 1:400,000.” NCT05019638

“Hyperbaric bupivacaine 0.5% will be administered at the dose of age divided by 5 (in ml).” NCT06801600

“30 participants had received 1 mL/kg 0.25% bupivacaine. Post operative pain was assessed.” NCT07140627

“Group A : will receive bupivacaine 0.25% + dexmedetomidine 1 mic/kg, total volume (20 ml)” NCT06294665

“subjects will receive 5, 10 or 20 ml of 0.5% bupivacaine will be incrementally injected.” NCT02453360

“Spinal anesthesia with heavy bupivacaine combined with femoral blockade with bupivacaine” NCT02322372

“A solution (10 ml) containing 1.5 mg/ml bupivacaine and 10 µg/ml fentanyl was prepared.” NCT05101291

“isobaric bupivacaine 0.5% 10 mg together with preservative-free morphine was injected.” NCT01477190

“0.25% Bupivacaine 25 ml each side for quadratus lumborum block without spinal morphine” NCT03199170

“Standardized spinal mixture of 10.25 mg hyperbaric bupivacaine, and 0.125 mg morphine.” NCT06418308

“20 ml bupivacaine 0.25% will be injected + 2 mg midazolam in 1 ml saline on each side.” NCT05261672

“Normal saline 2 ml will be mixed with 48 ml bupivacaine 0.125% in an elastomeric pump.” NCT05323214

“We will perform M-TAPA with totally 30 ml (15 ml for each side) of %0,25 bupivacaine.” NCT05179629

“preemptive pudendal nerve blockade with 10 ml of 0 .5 % Bupivacaine with epinephrine.” NCT02409498

“We will perform M-TAPA with totally 40 ml (20 ml for each side) of %0,25 bupivacaine.” NCT05199922

“2.5 mL 0.5% hyperbaric bupivacaine + 5 µg dexmedetomidine (0.5 mL), total volume 3 mL” NCT07326397

“Injection of 10 mL of .25% bupivacaine, followed by 10 mL of 98% dehydrated alcohol.” NCT04809935

“The patients will receive 0.1 mg morphine with 15 mg heavy bupivacaine intrathecally” NCT06319859

“ultrasound guided superficial cervical plexus blockage with 10 ml % 0.25 bupivacaineNCT03277599

“PCB with bupivacaine or saline with regard to the highest and lowest pain intensity” PMID 26573530 Nov 2015

“using 0.3ml of 0.5% Bupivacaine per nares delivered intranasal via the Tx360 device” NCT04466826

“15mg in 3ml hyperbaric bupivacaine intrathecally with 5 μg in 0.5ml dexmedetomidine” NCT06837844

“BupiZenge is a lozenge that dissolves slowly in the mouth and contains bupivacaine.” NCT07672236

“Erector spinae plane block (ESPB) using multilevel injections of bupivacaine 0.25%.” NCT06884852

“0.5% bupivacaine (0.3 ml∙kg-1) was then injected after a negative aspiration test.” NCT04355468

“flow rate of 2ml/hour of 0.25% bupivacaine diluted in accordance to patient weight” NCT00884650

Bupivacaine hydrochloride is a commonly used local anesthetic in spinal anesthesia” NCT03230474

“300-mg bupivacaine (three INL-001 100-mg bupivacaine HCl collagen-matrix implants)” PMID 30467808 Nov 2018

“plain or heavy Bupivacaine hydrochloride 10 mg (2 mL) injected in the spinal canal” NCT05706844

“Injection of Bupivacaine 0.5% 20 ml into the thickness of the right abdominal wall” NCT03532906

“PNB will be performed with 0.5% bupivacaine and 10cc will be injected bilaterally.” NCT04171050

Bupivacaine is FDA-approved for use as a local or regional anesthetic for surgery.” NCT05763667

“a bolus of 40 mL of 0.25% bupivacaine with 1:400,000 epinephrine will be injected” NCT03408483

“They will receive 20 mg of 0.5% hyperbaric bupivacaine plus 25 microgram fentanyl” NCT06550180

“Up to a maximum of 10mL of 0.5% bupivacaine infiltration in the buccal graft site” NCT05300685

“20 ml 0.25% plain bupivacaine (10ml 0.5% bupivacaine added to 10ml normal saline)” NCT06871033

“irrigation analgesia by 5 ml bupivacaine 0.50% plus 20 ml normal saline (Group N)” NCT07370181

“injection of 3 ml 0.25% bupivacaine in 1:200.000 adrenaline ,1.5 ml on each side” NCT04614259

“20 ml of 0.25% bupivacaine plus 5 ml of normal saline containing 250 mg of MgSO4” NCT06166108

“30ml of Exparel ((bupivacaine liposome injectable suspension) 1.3% ( 13.3mg/ml))” NCT02274077

“The local anesthetic will be a 2:1 mix of 1.5% mepivacaine and 0.5% bupivacaine.” NCT03138577

“inject 20 mL (5mL lidocaine 2% and 15 mL bupivacaine 0.25%) at each level of T4” NCT04425447

“with 7.5mg of hyperbaric bupivacaine was given for a patient 18-75 years of age” NCT05257941

“Patients will receive 29 ml bupivacaine 0.25% + 1 ml dexmedetomidine 0.5 μg/kg.” NCT06684535

“Control patients will have a TAP block with 5 cc of bupivacaine on both sides.” NCT03294109

“A dose of 0.25% bupivacaine 20 mL will be injected in each side (total 40 mL).” NCT05630404

“medications such as Gabapentin, Tylenol, Meloxicam, Bupivacaine, or Ketorolac.” NCT04176783

Bupivacaine will be used as the main local anesthetic medication in the study.” NCT03730714

“7.5 mg (low dose) hyperbaric bupivacaine 0.5% (Marcaine®, AstraZeneca, Sweden)” NCT06382220

“10mL of 133mg liposomal bupivacaine with 5mL of 0.5% bupivacaine (15mL total)” NCT04047446

“Both groups will receive port site infiltration with bupivacaine 0.25% 20 ml.” NCT06343753

“Group 1: patient controlled epidural analgesia (PCEA) with bupivacaine 1mg/mL” NCT01074190

“Lower extremity peripheral nerve block without Exparel: 0.25-0.5% bupivacaineNCT05494645

“patients received (0.5% hyperbaric bupivacaine 12.5 mg + dexmedetomidine 4μg)” NCT07051512

“Patients received vastus lateralis nerve block with 5 ml of bupivacaine 0.5%.” NCT06809842

“5 mic dexmedetomidine will be given intrathecally added to 2.5 mg bupivacaineNCT06823349

“addition of 1 µg/kg of clonidine to bupivacaine 1 mg/kg as spinal anesthesia” NCT01075490

“A total of 30 mL of 0.375% bupivacaine will be injected (maximum of 3mg/kg).” NCT03413163

“All patients will receive a spinal anesthetic using Fentanyl and BupivacaineNCT02197273

“the periarticular injection (each side 10 ml of 0.25% Bupivacaine) was done.” NCT04314505

“Thoracolumbar Interfascial Plane Block using Bupivacaine and dexmedetomidine” NCT06690021

“20mL of 0.25% bupivacaine with 1:400,000 epinephrine and 1:600,000 clonidine” NCT02741713

“second group will receive the caudal block, we use bupivacaine 0.5 mg / kg.” NCT06427174

“a dose of 0.25% bupivacaine (Buvasin %5 flakon) 20ml will be injected here.” NCT06084403

“Self-medication with a bolus 2ml of 0.125% bupivacaine via the PCEA system” NCT02478372

“1.3 % liposomal Bupivacaine in patients undergoing total knee arthroplasty” NCT03303794

“Hyperbaric bupivacaine 0.5% (3 ml) was administered into the spinal space.” NCT03240055

“Standard of care will consist of 0.25% Bupivacaine HCl TLIP injection 30mL” NCT06350981

“will receive bupivacaine 0.25% (3ml) + normal saline, total volume (5 ml).” NCT07380139

Bupivacaine 7.5mg (1.5ml) + fentanyl 25mcg in unilateral spinal anesthesia” NCT07262398

“0.75 ml of 0.5% Bupivacaine in conjunction with 0.5 mcg/kg dexmedetomidine” NCT03480607

“Lignocaine and Bupivacaine are two commonly used local anesthetic agents.” NCT00950625

“Thereafter, 2 ml of bupivacaine 0.5% will be injected to block the nerve.” NCT03762343

Bupivacaine is a local anesthetic commonly used via caudal epidural route” NCT05717374

“an injection of 10cc bupivacaine (plus \~1cc epinephrine and bicarbonate)” NCT03867539

“20ml of 0.25% bupivacaine will be injected in each side of the TAP block” NCT03060070

“local anesthetic (ropivacaine 0.2%, 2.0 mL or bupivacaine 0.25%, 2.0 mL)” NCT07431944

“Bilateral TAP Blocks with combination of regular Bupivacaine and EXPAREL” NCT03638011

“different anaesthetic substances with a local action (e.g. bupivacaine)” NCT02818985

“participants will be infiltrated with only bupivacaine around the wound” NCT06076707

“10-15mg hyperbaric bupivacaine and 30µg fentanyl intrathecally injected” NCT04160598

“12.5 mg (2.5 mL) of 0.5% hyperbaric bupivacaine + 5 µg dexmedetomidine” NCT07395271

Bupivacaine 9 mg intrathecal single shot injection at start of surgery” NCT00537472

“6ml hyperbaric bupivacaine 0.5% + hyaluronidase (50 IU) in 1ml saline” NCT03312959

“0.25% bupivacaine with epinephrine (1:100k), with total volume of 2mL” NCT03780478

“Spinal injection: bupivacaine 17.5 mg (3,5 mL) + 0.25 mL 0.9% saline.” NCT00992082

“Patients will receive 20 ml 0.25% bupivacaine on each side TAB block.” NCT05323565

“regional nerve block with a local anesthetic (Lidocaine/Bupivacaine)” NCT03453151

“The combination contains 0.25% bupivacaine hydrochloride (2.5 mg/mL)” NCT06456255

“the drug mix included lidocaine, bupivacaine and water for injection” NCT02245126

“30 mL of 0.25% bupivacaine will be injected as the local anesthetic.” NCT06773780

“bilateral ESP block will be injected with 20 ml of 0.25% bupivacaineNCT04749095

“3ml of bupivacaine without vasoconstrictor 0.25% for neural blockade” NCT05792774

“30 ml of 0.25% BUPIVACAINE and ADRENALIN at 1: 200,000 concentration” NCT03395912

Bupivacaine is a local anesthetic agent commonly used in ESP block.” NCT05855798

“Intraoperative injection of 0.25% bupivacaine at each incision site” NCT06709716

“Intrapleural nebulization of bupivacine (10 ml of bupivacaine 0.5%)” NCT05282251

“transversus abdominus plane block using 40 ml of bupivacaine 0.25%” NCT04623632

“20 ml of 0. 25% bupivacaine plus one mL normal saline bilaterally.” NCT03746418

“We will carry out the TAP block using 0.5 ml/ kg bupivacaine 0.25%” NCT04539314

“Epidural anesthesia, with a constant infusion of 0.25% bupivacaineNCT05844800

“50 mg bupivacaine hydrochloride 0.5% (AstraZeneca, Cenexi, France)” NCT05324995

“A total of 20ml bupivacaine 0.25% are then injected into the ESP.” NCT04110210

“less than 1 mL/kg of 0.25% bupivacaine with epinephrine 1:200,000” NCT03408340

“A 20 ml of 0.25% plain bupivacaine will be injected on each side.” NCT05475561

“10 mg of 0.5% hyperbaric bupivacaine (Buvanest Spinal 0.5% Heavy)” NCT02716129

“using 20 ml Bupivacaine 0.25% by an experienced anesthesiologist” NCT06362915

“7.5 mg plain bupivacaine (Astra) will be injected intrathecally.” NCT00119184

“0.25% bupivacaine injection in 6 different locations in abdomen.” NCT02007096

“A single betamethasone and bupivacaine intra-articular injection” NCT01381081

“A total of 25 ml bupivacaine 0.5% will be injected into the ESP.” NCT04118101

“40 mls of 0.255 bupivacaine will be infiltrated at skin incision” NCT03077581

“ESPB using local anesthetic 20 ml 0.25% bupivacaine on each side” NCT06957574

“Hyperbaric bupivacaine 10-15mg plus intrathecal morphine 100mcg” NCT03518463

“Anesthetic will be 0.5% bupivacaine with 1:100,000 epinephrine.” NCT05292677

“One receiving ropivacaine, one receiving liposomal bupivacaine.” NCT04801368

“30 ml of bupivacaine 0.25% solution will be used for the block.” NCT05905510

“Femoral Nerve Block with 40ml bupivacaine plus 0.5% epinephrine” NCT01911949

“HTX-011 (bupivacaine/meloxicam), 300 mg/ 9 mg via instillation.” NCT03695367

“Group B (Blockade with Bupivacaine): 30 mL bupivacaine (0.25%)” NCT07081581

“ultrasound-guided (USG) ACB with bupivacaine and dexamethasone” NCT04715152

“In group A intraperitoneal bupivacaine is used for pain relief” NCT07650760

“10 ml of 5% bupivacaine (Carbostesin®) was used for each side.” NCT00472446

“Injection of 30 mL local anesthetic solution bupivacaine 0.25%” NCT07037992

“the local anesthetic bupivacaine 0.5% into each affected disc” NCT04735185

“The eutectic mixture of lidocaine + prilocaine + bupivacaine.” NCT00932542

“using 0.25% bupivacaine (0.5 mL/kg) before surgical incision.” NCT07301528

“Exparel is such a compound that slowly releases bupivacaine.” NCT02607579

“2 mL of a 50:50 mixture of 2% lidocaine and 0.5% bupivacaineNCT01670825

“20 ml solution containing 0.25% bupivacaine + normal saline” NCT07182110

“Bilaterally inject (5ml) bupivacaine 0.5% for each segment.” NCT03437213

“(1 mL/kg of bupivacaine 0.25% plus 1 μ/kg dexmedetomidine).” NCT03482947

“0.1% Bupivacaine and 2microgram\\ml Fentanyl every one hour” NCT06494280

“Intrathecal injection of bupivacaine, fentanyl and morphine” NCT06570343

“intrathecal tramadol 20mg with Hyperbaric 0.5% bupivacaineNCT07294352

“Direct injection of 0.25% bupivacaine into surgical wounds” NCT04426500

“12 mg of isobaric "Bupivacaine 0.5%", "Bucaine®," (2.4 ml)” NCT06769737

“Preoperative Bupivacaine 0.5%, perineurally as single shot” NCT01303120

“liposomal bupivacaine 1.3% (260 mg) will be administered.” NCT02178553

“patients will be injected with 20 cc of 0.25% BupivacaineNCT05256056

“intrathecal bupivacaine 6 mg for BMI less than 27.5 kg/m2” NCT01291186

“group administered Ultrasound guided STB with bupivacaineNCT07046325

“20 ml of 0.25% Bupivacaine will be given at incision site” NCT05480111

Bupivacaine was used for postoperative analgesia block.” NCT06116409

“A total of 10 ml of 0.25% bupivacaine will be injected.” NCT03450226

“TAP block with local anesthetic: Bupivacaine 0.25% 10ml” NCT07558226

“Injection bupivacaine 0.25% used as a local anesthetic.” NCT03734848

“injected 10 mL of 0.1% bupivacaine with 100 Botox units” NCT05099835

bupivacaine 0.25% + morphine 5 mg in total volume 10 ml” NCT04033471

“dexamethasone + plain Bupivacaine injected epidurally.” NCT03231215

“a dose of 0.25% bupivacaine 20ml will be injected here” NCT04189640

“Drugs used are Bupivacaine 0.25% with volume of 25 ml.” NCT06750627

“30 ml of 0.25% concentration bupivacaine will be used” NCT06866054

Bupivacaine(scalp block) R/A 20ml 0.5% Postoperative” NCT05474040

“EXPAREL (bupivacaine liposome injectable suspension)” NCT01509638

“20 ml of 0.25% Bupivacaine in each site of injection” NCT05369468

“spinal anesthesia with hyperbaric bupivacaine 10 mg” NCT05525819

“using 20 mL 0.25% bupivacaine and 21 G block needle” NCT03543202

“15cc 0.25% of Bupivacaine + Dexamethasone 8 mg 2cc” NCT07049835

“10 ml of bupivacaine 0.5 % mixed with 10 ml saline” NCT02122510

“20cc of bupivacaine 0.25% will be injected slowly” NCT03422354

“20 mL of 0.25% bupivacaine will be administered” NCT06910696

“20 mg isobaric bupivacaine + 1 ml normal saline” NCT03731468

“Erector spinae thoracic block with bupivacaineNCT05521789

“lidocaine 1% and bupivacaine 0,5% 1:1 mixture” NCT03454789

“20 ml bupivacaine 0.5% + 20 ml normal saline.” NCT03967392

“0.25% bupivacaine with epinephrine 1:200 000.” NCT06945263

Bupivacaine is a well-known local anesthetic.” NCT02067078

“10ml of 0.125% isobaric bupivacaine injected” NCT05810012

“Long-Acting Liposomal Bupivacaine (Exparel®)” NCT04826484

“20 mg bupivacaine intrathecal administration” NCT06082232

“20 mcg fentanyl in 10 mL 0.125% bupivacaineNCT03120780

bupivacaine 0.25% in a dose of (0.5 ml / kg” NCT06183073

“20 ml of 0.25% bupivacaine will be injected” NCT07610070

“Drug:Bupivacaine 0.25% Injectable Solution” NCT04768764

Bupivacaine liposome injectable suspension” NCT02353754

“PIFB done with bupivacaine and epinephrine” NCT05676814

bupivacaine liposome injectable suspension” NCT04002089

Bupivacaine Liposome Injectable Suspension” NCT07222748

“20 ml of bupivacaine 0.25% paravertebrally” NCT02935933

“0.5% bupivacaine with epinephrine (2.25mL)” NCT04951128

Bupivacaine 0.5% (Astra Zeneca) 2 mg/Kg.” NCT03319563

“10 ml of liposomal bupivacaine (133 mg)” NCT03827291

“40 mL of bupivacaine/lidocaine mixture” NCT04336917

“20ml of 0.25% bupivacaine inTAP block” NCT07482709

“mixture of bupivacaine and sufentanil” NCT04755712

“Administration of bupivacaine 2.5 mg.” NCT01991743

“using isobaric bupivacaine 0.5% 50 mg” NCT06451705

“10 mg hyperbaric Bupivacaine ( 2ml )” NCT05474001

“injection of 30 ml bupivacaine 0.25%” NCT06519708

“local anesthetic (0.25% bupivacaine)” NCT03187080

“Drug:Caudal bupivacaine 0.25% 1ml/kg” NCT02416063

“4 ml of hyperbaric bupivacaine 0.5%” NCT03276325

“0.5% hyperbaric Bupivacaine 2.2 ml” NCT07094802

“0.25% bupivacaine with epinephrine” NCT04530149

“with 20mL of bupivacaine 0.125 %.” NCT05671081

“300 mg bupivacaine/9 mg meloxicam” NCT03907176

bupivacaine 0.75% 1.6 mL (12mg)” NCT01943565

“Exparel (liposomal bupivacaine)” NCT05355597

“EXPAREL (Liposomal Bupivacaine)” NCT03377595

“3mL of bupivacaine (heavy) 0.5%” NCT05074823

“Exparel (liposomal bupivacaine)” NCT05823363

“ear block by 0.25% bupivacaineNCT03569046

Bupivacaine (local anesthetic)” NCT03043027

“10 ml of bupivacaine (0.25%)” NCT05180214

“266mg bupivacaine liposomes” NCT06427044

Bupivacaine 0.25% injection” NCT05654519

“0.5% hyperbaric bupivacaineNCT04689217

Bupivacaine HCl 75mg (30mL)” NCT05161637

“20 ml of bupivacaine 0.25%” NCT02462681

“and 4 mL bupivacaine 0.5%.” NCT02534012

Bupivacaine Hydrochloride” NCT03885596

“3 ml of bupivacaine 0.5%” NCT02355678

Bupivacaine 0.5% 10 mg” NCT01511627

Bupivacaine HCl 2mg/kg” NCT03682302

“1 mL bupivacaine 0.5%” NCT07547605

“Low dosis bupivacaineNCT03691337

“Liposomal bupivacaineNCT03927326

Bupivacaine, kenalog” NCT03291197

“standard bupivacaineNCT04180943

Bupivacaine 0.125%” NCT03245359

“Drug: BupivacaineNCT02658760

“Drug: BupivacaineNCT02514343

Bupivacaine only” NCT03106818

“0.5% bupivacaineNCT06186921

BupivacaineNCT02453360

BupivacaineNCT02284386

BupivacaineNCT03682302

BupivacaineNCT06930183

BupivacaineNCT07624890

NCT02284386

NCT04003506

NCT05374499

NCT01326039

NCT07570940

NCT04294732

NCT02891798

NCT02726620

NCT05892887

NCT02591888

NCT01939314

NCT03845894

NCT01206608

NCT03231436

NCT02882633

NCT05117021

NCT05893771

NCT02005575

NCT05609565

NCT03106753

NCT01507220

NCT04897841

NCT01206595

NCT03846284

NCT03975283

NCT02662660

NCT03745040

NCT04294329

NCT05264805

NCT05672394

NCT03538496

NCT03015961

NCT03067168

NCT03106519

NCT07683182

NCT04538391

NCT03974932

NCT05732532

NCT06740214

NCT04727229

NCT02768376

NCT03744689

NCT02662036

NCT04293809

NCT01690663

NCT03149887

NCT03459105

NCT04215614

NCT05999734

NCT03015857

NCT07616882

NCT03243500

NCT03460041

NCT02847013

NCT03292926

NCT01224145

NCT06046105

NCT02703415

NCT03538483

NCT07569952

NCT03067740

NCT00195312

NCT03577860

NCT07653490

NCT01906944

NCT03066544

NCT02922985

NCT07640256

NCT03847792

NCT07348016

NCT07469826

NCT06863714

NCT02755532

NCT02783586

NCT03126084

NCT05731973

NCT06908837

NCT03353363

NCT01621230

NCT06092073

NCT03632161

NCT03293472

NCT00547989

NCT03067896

NCT07393386

NCT06135545

NCT03887650

NCT06020781

NCT05117307

NCT06153602

NCT00508066

NCT02210260

NCT06665438

NCT07213635

NCT03844451

NCT02818894

NCT02397330

NCT03972397

NCT02909257

NCT04361513

NCT07654556

NCT02820688

NCT06662175

NCT03508830

NCT02059070

NCT04461028

NCT02058303

NCT03046719

NCT05967936

NCT01907191

NCT02408419

NCT03704441

NCT07684365

NCT06635889

NCT04685421

NCT02927379

NCT07573969

NCT05596552

NCT03702621

NCT03383588

NCT03642457

NCT07090928

NCT03843970

NCT03065569

NCT03749408

NCT00332735

NCT06789393

NCT07049094

NCT01398982

NCT05276258

NCT06344091

NCT06789575

NCT07681648

NCT02352922

NCT03652103

NCT03386630

NCT03198403

NCT03105115

NCT06864416

NCT00180687

NCT03652116

NCT04709211

NCT07255768

NCT01314144

NCT05359731

NCT06137924

NCT03970655

NCT03198338

NCT02349542

NCT04709250

NCT06864663

NCT06784180

NCT06783764

NCT07497646

NCT04835116

NCT01507233

NCT05069350

NCT05357690

NCT01832675

NCT07574385

NCT07684989

NCT07137208

NCT00808327

NCT00624910

NCT02349581

NCT05830630

NCT02601027

NCT07108465

NCT06616441

NCT02024724

NCT03969875

NCT07263295

NCT02353182

NCT01662401

NCT03383198

NCT04213924

NCT03230227

NCT03027661

NCT02725359

NCT03244540

NCT06720337

NCT02519023

NCT03643757

NCT02573597

NCT07201987

NCT05413902

NCT04102267

NCT04336046

NCT06860893

NCT02866409

NCT07066111

NCT02353676

NCT06667024

NCT06225895

NCT03001453

NCT03968822

NCT03488888

NCT02981095

NCT04189198

NCT05998551

NCT05891613

NCT06702202

NCT03070054

NCT05491187

NCT00661466

NCT07616180

NCT05851768

NCT04766996

NCT07576309

NCT07565662

NCT07156968

NCT01244932

NCT07468604

NCT05702827

NCT03064633

NCT02908412

NCT04218149

NCT06301503

NCT07232108

NCT06790732

NCT06535256

NCT04911062

NCT02292082

NCT03967288

NCT03151434

NCT02980926

NCT06301334

NCT01874236

NCT02025374

NCT04101682

NCT06133881

NCT03351348

NCT03606889

NCT02752971

NCT03606902

NCT04362566

NCT02691572

NCT07577934

NCT03463083

NCT02381717

NCT06022614

NCT07564180

NCT01394523

NCT00519584

NCT03064165

NCT04212845

NCT07008443

NCT02397603

NCT00523289

NCT04539730

NCT01756573

NCT00810563

NCT04212832

NCT01868425

NCT01205360

NCT01896960

NCT02570022

NCT02168959

NCT02406300

NCT02472314

NCT01756560

NCT03355716

NCT02674113

NCT06568289

NCT01638052

NCT03232957

NCT02428257

NCT02473198

NCT05341323

NCT07280195

NCT05659823

NCT07441902

NCT02179892

NCT03196505

NCT01550302

NCT01616108

NCT04116554

NCT02863120

NCT00818363

NCT01615939

NCT07579975

NCT03128216

NCT05406765

NCT06284434

NCT03883763

NCT04286035

NCT02822196

NCT04397458

NCT02381353

NCT06531603

NCT04117074

NCT06942884

NCT04411329

NCT00635037

NCT01945554

NCT07687290

NCT01454609

NCT03152877

NCT05575999

NCT05824338

NCT02947178

NCT04212039

NCT02689024

NCT02665273

NCT02554357

NCT03706313

NCT07614802

NCT02959996

NCT05814744

NCT07467356

NCT06625606

NCT01423292

NCT00921102

NCT05276908

NCT02008617

NCT01582022

NCT07388251

NCT05550597

NCT07203794

NCT02089932

NCT05456490

NCT05672680

NCT03103100

NCT03195413

NCT07081373

NCT00807209

NCT04322760

NCT04189783

NCT03022526

NCT07643506

NCT00974961

NCT05530811

NCT06253260

NCT07678073

NCT04917029

NCT02507700

NCT01015807

NCT04284930

NCT01759524

NCT01756586

NCT02398123

NCT06055101

NCT01698593

NCT03411330

NCT06179004

NCT07560501

NCT03757715

NCT04540848

NCT02336529

NCT03504865

NCT04065919

NCT03602469

NCT02752308

NCT03653416

NCT03530280

NCT07440576

NCT02654860

NCT00927888

NCT06989866

NCT00974350

NCT05303311

NCT04634721

NCT05963139

NCT05767749

NCT03261193

NCT04680923

NCT06743919

NCT03412474

NCT05241054

NCT07387484

NCT04508894

NCT03155568

NCT01731782

NCT06815887

NCT00508976

NCT07092891

NCT01837290

NCT06098105

NCT02453321

NCT06833697

NCT07275320

NCT03063073

NCT03592537

NCT04635176

NCT03356899

NCT02630160

NCT05996133

NCT05177991

NCT05925478

NCT03853330

NCT07688395

NCT03072329

NCT00465231

NCT06386770

NCT02671227

NCT01701115

NCT04680221

NCT04932083

NCT03302039

NCT02923869

NCT05232084

NCT07689162

NCT02458547

NCT04494880

NCT05577260

NCT02426736

NCT05794828

NCT05781854

NCT02001948

NCT02385435

NCT06937385

NCT06575699

NCT00405262

NCT04480775

NCT04979338

NCT02862912

NCT04398329

NCT04903743

NCT03156322

NCT06904703

NCT07400146

NCT05671172

NCT03854344

NCT02289079

NCT00845962

NCT02946294

NCT03666663

NCT03563625

NCT03808129

NCT05785377

NCT07689617

NCT05417113

NCT06600048

NCT04300231

NCT02624856

NCT04947007

NCT06270147

NCT03346993

NCT02785055

NCT02925832

NCT03958513

NCT04095013

NCT07349810

NCT07030647

NCT02723487

NCT02346110

NCT07385352

NCT07285083

NCT06633068

NCT02214810

NCT01677143

NCT02961842

NCT02544893

NCT05661253

NCT02990702

NCT06820203

NCT01756443

NCT02299349

NCT03486548

NCT04245774

NCT05877690

NCT04020133

NCT07556614

NCT03379987

NCT03261921

NCT03957499

NCT05720949

NCT07138781

NCT07465406

NCT03109691

NCT02962024

NCT02713178

NCT05361642

NCT01300377

NCT02731950

NCT07555821

NCT02824770

NCT06820216

NCT07465185

NCT06349668

NCT06620614

NCT04345341

NCT02697955

NCT03708198

NCT03956966

NCT02513433

NCT07228039

NCT07643792

NCT03156296

NCT03304444

NCT06069791

NCT04094532

NCT06575010

NCT02065219

NCT04941170

NCT02127489

NCT03701126

NCT04867369

NCT02670759

NCT02287623

NCT04019834

NCT04360421

NCT02787226

NCT01593566

NCT01838707

NCT05109416

NCT05005260

NCT06235606

NCT02537860

NCT03110003

NCT03305575

NCT00678379

NCT03305666

NCT02000973

NCT03838133

NCT03283436

NCT06173466

NCT03388671

NCT02713230

NCT06219837

NCT04865211

NCT04353414

NCT05193227

NCT06656299

NCT07587203

NCT05017584

NCT02287246

NCT03413371

NCT01566838

NCT03074097

NCT02155010

NCT01060774

NCT03388814

NCT02064530

NCT03024957

NCT01878864

NCT03954639

NCT04732507

NCT02765815

NCT03234374

NCT02426164

NCT04640896

NCT07094386

NCT06429501

NCT04403724

NCT06004882

NCT03262688

NCT07651722

NCT01838928

NCT03074773

NCT04126824

NCT02825056

NCT07322445

NCT02052557

NCT06338865

NCT03344679

NCT05379374

NCT02065804

NCT02450045

NCT03307174

NCT03735771

NCT03672500

NCT04209439

NCT05686395

NCT05094323

NCT02299908

NCT02643563

NCT02359175

NCT07292324

NCT03307590

NCT07276906

NCT05091138

NCT02576782

NCT05017246

NCT03145584

NCT06655454

NCT05751421

NCT02393664

NCT01701414

NCT06737458

NCT06737341

NCT01582607

NCT02525718

NCT02449915

NCT03502018

NCT04559347

NCT04246697

NCT02713490

NCT01636869

NCT07658521

NCT02603900

NCT01429584

NCT03159000

NCT01133119

NCT03444636

NCT04833777

NCT06745986

NCT04611958

NCT02890199

NCT03187379

NCT07632820

NCT02100579

NCT05332028

NCT01126593

NCT05834023

NCT07550348

NCT06537323

NCT05624151

NCT06085417

NCT03101137

NCT05140499

NCT02084368

NCT02543801

NCT07436546

NCT02758405

NCT02376205

NCT05751148

NCT01861041

NCT02376192

NCT06288841

NCT03234816

NCT03856788

NCT03612947

NCT04221568

NCT01272921

NCT02480621

NCT02285491

NCT03664986

NCT01880775

NCT00574015

NCT07216820

NCT02982889

NCT03013361

NCT07246642

NCT03020563

NCT03443778

NCT04221880

NCT02764723

NCT07274215

NCT01583166

NCT02577432

NCT04733560

NCT03949686

NCT07644923

NCT02949674

NCT02244086

NCT02861950

NCT03011333

NCT02049970

NCT02937792

NCT03013075

NCT04646707

NCT01977352

NCT03100994

NCT07027540

NCT04318158

NCT05121168

NCT04068766

NCT01442558

NCT01977339

NCT05082441

NCT05068063

NCT02669186

NCT02526199

NCT04777591

NCT05964868

NCT06006624

NCT06677827

NCT00403663

NCT04468542

NCT03004222

NCT02805920

NCT03767920

NCT04133051

NCT06736392

NCT07435909

NCT03802864

NCT07058194

NCT03948386

NCT01219062

NCT06289790

NCT03185351

NCT03341234

NCT01219088

NCT06430112

NCT05648708

NCT05118399

NCT02707250

NCT05279092

NCT07631416

NCT05244252

NCT02284282

NCT06560892

NCT04959721

NCT03415087

NCT03859024

NCT07023991

NCT04974385

NCT06547255

NCT04173312

NCT04864210

NCT02331563

NCT06812741

NCT02879435

NCT05707754

NCT04577690

NCT03902782

NCT05095025

NCT06558331

NCT05244525

NCT00626886

NCT04930887

NCT02976597

NCT03060681

NCT04648358

NCT02861716

NCT07590752

NCT06369948

NCT06271265

NCT04172727

NCT05447871

NCT06590402

NCT00151346

NCT00557843

NCT02976571

NCT04134442

NCT05900427

NCT03359811

NCT05605639

NCT04134637

NCT03859635

NCT07146685

NCT00298571

NCT06714279

NCT01005459

NCT02988700

NCT06747975

NCT01751347

NCT04825704

NCT04446715

NCT03183596

NCT01921231

NCT06653621

NCT06879288

NCT04443634

NCT05919732

NCT04609033

NCT03993314

NCT02375100

NCT05090761

NCT05118620

NCT07334132

NCT04207411

NCT03769818

NCT06514365

NCT03599635

NCT05663801

NCT05224089

NCT01667315

NCT06959147

NCT04544228

NCT01785459

NCT03770013

NCT00358280

NCT02682498

NCT03079076

NCT03225313

NCT05260008

NCT07256938

NCT06958718

NCT00197353

NCT02521831

NCT00050362

NCT02606448

NCT00795223

NCT06313632

NCT01203644

NCT05919173

NCT04427904

NCT03401450

NCT03439787

NCT05708742

NCT07071012

NCT06002152

NCT05845125

NCT07698665

NCT06735443

NCT07117565

NCT03649763

NCT05918796

NCT05397236

NCT00484159

NCT07046390

NCT00197327

NCT03470363

NCT05068960

NCT02804126

NCT03545516

NCT05223244

NCT07512635

NCT03182114

NCT02512861

NCT07451327

NCT02031510

NCT03182088

NCT04651556

NCT02282774

NCT03034382

NCT07139522

NCT05813158

NCT01528722

NCT04479371

NCT06680167

NCT03834454

NCT02930733

NCT02538679

NCT06298370

NCT03059498

NCT05139030

NCT00296751

NCT01378949

NCT07013955

NCT04393207

NCT02578719

NCT07171125

NCT02682082

NCT03730402

NCT03316118

NCT00478179

NCT06107660

NCT07432711

NCT06537518

NCT04756050

NCT03507387

NCT03906617

NCT03483415

NCT02622126

NCT03316352

NCT03248791

NCT03438240

NCT06290583

NCT04272320

NCT05222334

NCT03375112

NCT03663283

NCT03639389

NCT02802683

NCT03080363

NCT04715165

NCT05843838

NCT03005171

NCT00529126

NCT07058493

NCT07661212

NCT04272086

NCT03535792

NCT02764008

NCT03646006

NCT02696915

NCT03164590

NCT06271707

NCT07366905

NCT05133687

NCT01565512

NCT04168879

NCT07121764

NCT05664711

NCT02046772

NCT01786655

NCT03729375

NCT02681796

NCT04368364

NCT03712735

NCT04168710

NCT04908579

NCT03799757

NCT02988219

NCT03214510

NCT00450099

NCT02412930

NCT01957631

NCT03541655

NCT02181205

NCT06995352

NCT02566226

NCT02860949

NCT05687981

NCT06956950

NCT03180099

NCT02801188

NCT03318757

NCT03248817

NCT06734975

NCT02566096

NCT03728946

NCT04908449

NCT07340801

NCT04032327

NCT02621255

NCT05664958

NCT03560362

NCT02121119

NCT02801201

NCT02161484

NCT07212114

NCT01829399

NCT06694077

NCT04382144

NCT03436836

NCT04673812

NCT06356415

NCT04814433

NCT02988050

NCT03482973

NCT05902780

NCT03527836

NCT04205344

NCT01303107

NCT02365857

NCT02800694

NCT05790044

NCT02365909

NCT02219087

NCT03862287

NCT06381401

NCT07358299

NCT05644496

NCT02515422

NCT04269460

NCT05315271

NCT02495220

NCT04251962

NCT05734625

NCT06935669

NCT00871442

NCT03514277

NCT05590234

NCT04471597

NCT05860010

NCT03862404

NCT05565235

NCT07412522

NCT05097118

NCT03165383

NCT06416891

NCT06569953

NCT05280197

NCT06955455

NCT06143306

NCT07631091

NCT02374320

NCT04167176

NCT02666794

NCT03909594

NCT01584947

NCT01843296

NCT01356797

NCT03264430

NCT03253198

NCT03373591

NCT01903421

NCT05825872

NCT02456142

NCT02953210

NCT01308047

NCT02343432

NCT05190952

NCT00895843

NCT03586154

NCT02790099

NCT03040011

NCT02777749

NCT03713762

NCT02116842

NCT04737980

NCT02196441

NCT06060015

NCT06681805

NCT06416111

NCT05286190

NCT02400645

NCT02486549

NCT01303731

NCT03177252

NCT06148168

NCT03393117

NCT03236324

NCT05186454

NCT01960543

NCT04900116

NCT07668648

NCT02141178

NCT06474949

NCT03035617

NCT03434951

NCT05171179

NCT05015322

NCT01508832

NCT06752525

NCT07596810

NCT02121392

NCT02886286

NCT07236086

NCT02886429

NCT02198027

NCT06452147

NCT05271253

NCT00318292

NCT04165512

NCT02550782

NCT00314457

NCT03481517

NCT07535411

NCT03434678

NCT00801047

NCT02343263

NCT02616367

NCT03638960

NCT02420951

NCT02973958

NCT03084536

NCT00749749

NCT02044302

NCT03523000

NCT03265886

NCT03797079

NCT01961752

NCT03249662

NCT04082676

NCT07332130

NCT02487355

NCT06352398

NCT01972620

NCT01853176

NCT02435537

NCT04073056

NCT00287326

NCT01494259

NCT05552391

NCT03393572

NCT06498739

NCT03176459

NCT04204343

NCT02660918

NCT02462174

NCT04751344

NCT06432127

NCT05589363

NCT06728514

NCT04849858

NCT02414373

NCT05285800

NCT01558713

NCT02798835

NCT03863977

NCT07140640

NCT03372486

NCT06752629

NCT05317611

NCT02581566

NCT01147146

NCT04266132

NCT02775318

NCT01220024

NCT06291727

NCT04603911

NCT01972269

NCT03266081

NCT01927874

NCT00801138

NCT07606911

NCT03040167

NCT02496299

NCT06189781

NCT05391971

NCT04721054

NCT00578136

NCT01520415

NCT00991627

NCT05137288

NCT03796195

NCT05082155

NCT05688449

NCT05588557

NCT06122545

NCT02510287

NCT05216770

NCT03693638

NCT06570096

NCT06825286

NCT05603832

NCT05495750

NCT06114121

NCT03399435

NCT05482113

NCT02373410

NCT00993798

NCT01264575

NCT01563835

NCT02462148

NCT03174782

NCT07430085

NCT05526469

NCT02973581

NCT03474510

NCT07416084

NCT02277782

NCT07257874

NCT00993746

NCT04749797

NCT02777866

NCT02368054

NCT03432650

NCT03913091

NCT03780790

NCT07376798

NCT06683807

NCT07460115

NCT07518225

NCT02242201

NCT04579302

NCT02255500

NCT02252926

NCT03723447

NCT05635916

NCT06231355

NCT01243112

NCT07338916

NCT03324490

NCT03638635

NCT07245290

NCT04203290

NCT06507397

NCT03781388

NCT05374356

NCT03094663

NCT03865147

NCT00819962

NCT03009500

NCT00779467

NCT01538459

NCT01377415

NCT01964040

NCT02840526

NCT03722927

NCT02887222

NCT05216055

NCT01052012

NCT03636048

NCT03927911

NCT07002788

NCT03324984

NCT05904912

NCT07085481

NCT01534416

NCT04782778

NCT04477525

NCT03619785

NCT01279447

NCT04003987

NCT02222129

NCT06810375

NCT02506660

NCT02973451

NCT01364194

NCT05283980

NCT05537883

NCT07208253

NCT03715517

NCT06692010

NCT01497509

NCT05438992

NCT00562627

NCT01559740

NCT02534623

NCT03094481

NCT06146842

NCT03036085

NCT04928664

NCT03219086

NCT03272139

NCT04782960

NCT02124005

NCT05972681

NCT05161221

NCT05499689

NCT03830086

NCT03250507

NCT05425979

NCT03574376

NCT04748224

NCT00993226

NCT03117595

NCT04394533

NCT06685705

NCT07665762

NCT03134677

NCT07073209

NCT00802646

NCT06895382

NCT02540837

NCT03088371

NCT03926663

NCT02619409

NCT04963816

NCT02680548

NCT04783194

NCT05208801

NCT03682224

NCT03595397

NCT01632709

NCT07458321

NCT04787731

NCT05461092

NCT07485127

NCT07418671

NCT06997016

NCT01964781

NCT06330168

NCT02514980

NCT01276925

NCT04313764

NCT00600158

NCT07458295

NCT05044468

NCT02951884

NCT03252496

NCT03595514

NCT07194694

NCT03636542

NCT02582372

NCT06471348

NCT06050044

NCT05690282

NCT02223364

NCT03036605

NCT03039426

NCT03480308

NCT01087931

NCT02875015

NCT02618876

NCT02913573

NCT02740114

NCT07648784

NCT02253784

NCT05157841

NCT02497040

NCT07458282

NCT05003765

NCT04377204

NCT04928339

NCT03623230

NCT06331182

NCT02075411

NCT02740192

NCT03328299

NCT03498118

NCT07601750

NCT00887003

NCT02584452

NCT06806410

NCT03328533

NCT06557018

NCT03090152

NCT02190760

NCT04720287

NCT02447965

NCT05068661

NCT04202367

NCT06809998

NCT02463929

NCT07420712

NCT01328782

NCT05736549

NCT06411795

NCT03007966

NCT04784104

NCT06449430

NCT05905757

NCT04549844

NCT05029726

NCT04442750

NCT02858622

NCT03498092

NCT04996251

NCT03007927

NCT07458256

NCT05840328

NCT03219983

NCT07426666

NCT07178262

NCT06353529

NCT05715437

NCT06166602

NCT05792111

NCT05602038

NCT03427502

NCT01245868

NCT03496740

NCT05727098

NCT03427437

NCT06807554

NCT03237481

NCT02104414

NCT05906433

NCT04257682

NCT01561274

NCT01812044

NCT03720223

NCT07097493

NCT03269383

NCT03792191

NCT06120530

NCT03922620

NCT03787147

NCT03871478

NCT02036697

NCT04718259

NCT02086474

NCT06529432

NCT04786756

NCT03792009

NCT06731101

NCT07221019

NCT02159807

NCT04156581

NCT02550262

NCT05427500

NCT02762071

NCT02455609

NCT04888858

NCT02327923

NCT06587386

NCT04744675

NCT06644261

NCT04518462

NCT04157075

NCT00672347

NCT06367660

NCT01688596

NCT01902108

NCT07664618

NCT04417179

NCT00472134

NCT04036201

NCT06077214

NCT01040273

NCT01586806

NCT06276179

NCT03871049

NCT04785222

NCT05136040

NCT02037061

NCT02498171

NCT01994967

NCT05122351

NCT06951256

NCT05062356

NCT03869047

NCT06165991

NCT03918187

NCT04259645

NCT06541613

NCT03623256

NCT06565910

NCT02464176

NCT06847620

NCT01305603

NCT02074709

NCT01847339

NCT02652156

NCT05638620

NCT02930707

NCT05561010

NCT03587584

NCT06450028

NCT03115151

NCT06689358

NCT07329582

NCT06917898

NCT06145165

NCT03587636

NCT05602636

NCT02655523

NCT02971540

NCT06165679

NCT06756347

NCT03790566

NCT00815022

NCT06892600

NCT07663435

NCT03497364

NCT04158102

NCT03790007

NCT03790020

NCT02188394

NCT02852382

NCT02037802

NCT06619080

NCT07141589

NCT01096966

NCT01575028

NCT03007121

NCT07097844

NCT06950502

Known as 0.25% Bupivacaine 0.25% BupivacaineNCT02822196
Known as 0.5% bupivacaine, marcaine. 0.5% bupivacaine, marcaine.NCT01759524
Known as ANAWIN heavy “0.5% hyperbaric bupivacaine (ANAWIN heavy, Neon Laborotaries, India) 10mg (2ml)” NCT06367660
Known as AstraZeneca ClinicalTrials.gov intervention name — accepted as the source's own label NCT05387317
Known as BPV “bupivacaine (BPV)” PMID 34730810 Jan 2022
Known as Bucain “with a solution composed of 50 ml Bupivacaine Hcl 0.25% (Bucain® Weimer pharma, for Actavis Group PTC) and 0.5 mg of epinephrine Hcl” NCT05806307
1

NCT02445599

Known as Bucaine “12 mg of isobaric "Bupivacaine 0.5%", "Bucaine®," (2.4 ml)” NCT06769737
Known as BUP “We report the results of injection of bupivacaine (BUP) and botulinum toxin (BT) into agonist and antagonist muscles, respectively, to treat horizontal strabismus.” PMID 20126486 Dec 2009
Known as BUPIROP “one of the alveolus will be irrigated with 4ml of bupivacaine 0.5% with adrenaline vasoconstrictor 1: 200,000 (BUPIROP® 0.5%), the contralateral alveolus will be irrigated with...” NCT03950700
Known as Bupivacain “The aim of this study is to assess the efficacy of Mg sulfate ( 10% ) as an adjuvant to Bupivacain ( 0.25 % ) in an U.S guided QLB for postoperative analgesia and postoperative...” NCT06301789
56

“Postoperatively the epidural anesthesia is continued until the morning of the third postoperative day using bupivacain 1 mg/ml, fentanyl 2 µg/ml and epinephrine 2µg/ml.” NCT02026687

“epidural anesthesia: patients get an continuous infusion of a solution with bupivacain 1 mg/ml, fentanyl 1 ug/ml and adrenalin 1 ug/ml” NCT02030717

“Ultrasound guided bilateral parasternal injection of bupivacain 0.375%, 20ml, at 4th thoracic vertebral level.” NCT05681507

“20 mg Kenacort + 1 ml Bupivacain (2.5 mg/ml) will be injected into the affected facet joints.” NCT05852808

“0.5% bupivacaine (Bupivacain®) will be administered.” NCT01945554

Bupivacain 25% (Erector Spinae Plane Block)” NCT06422182

Bupivacain will be injected at port sites.” NCT02969187

Bupivacain (B) group” NCT06076707

“Drug: BupivacainNCT05405049

“Drug: BupivacainNCT06284434

“Drug: BupivacainNCT06350981

“Drug: BupivacainNCT05474001

“Drug: BupivacainNCT05656170

“Drug: BupivacainNCT05979493

“Drug: BupivacainNCT05261672

“Drug: BupivacainNCT07650760

“Drug: BupivacainNCT05788458

NCT05723341

NCT04943549

NCT04985500

NCT06231979

NCT04728308

NCT00728559

NCT06550414

NCT05178485

NCT07613801

NCT05404490

NCT05080985

NCT07149168

NCT06639503

NCT04809532

NCT00527332

NCT06856538

NCT04646967

NCT06838156

NCT06267820

NCT05880017

NCT06574022

NCT05431062

NCT03627897

NCT06766474

NCT06362915

NCT05993975

NCT05220813

NCT05245721

NCT00804674

NCT06112548

NCT05099250

NCT01395043

NCT07144215

NCT01220362

NCT07429448

NCT06243263

NCT06116409

NCT06315634

NCT00970086

Known as Bupivacain 1,25 mg/ml “Bupivicaine 1.25mg/ml (BUPIVACAIN Sintetica 0.125 % ™ (Bupivacain 1,25 mg/ml), Sintetica-Bioren, Couvet, Schweiz)” NCT02414373
Known as BUPIVACAIN Sintetica “Bupivicaine 1.25mg/ml (BUPIVACAIN Sintetica 0.125 % ™ (Bupivacain 1,25 mg/ml), Sintetica-Bioren, Couvet, Schweiz)” NCT02414373
Known as Bupivacaina ClinicalTrials.gov intervention name — accepted as the source's own label NCT01596660
Known as Bupivacaine 0.25% epidural solution Bupivacaine 0.25% epidural solutionNCT03715517
Known as Bupivacaine = Marcain Bupivacaine = MarcainNCT01367418
Known as Bupivacaine Collagen Sponge “Drug: Bupivacaine Collagen SpongeNCT01220024
Known as Bupivacaine extended-release liposome injection “Bupivacaine Extended Release Liposome Injection (Exparel TM) 133 mg diluted in 10ml of normal saline (13.3 mg/ml) will be injected with a 25 gauge needle directly into the...” NCT03318757
1

Bupivacaine extended-release liposome injection is a novel formulation of bupivacaine designed to achieve long-acting postoperative analgesia.” PMID 22067185 Dec 2011

Known as Bupivacaine HCI Bupivacaine HCI (1.8mL) 5% concentration, with epinephrine (1:200,000) is the investigational product.” NCT04787731
Known as Bupivacaine Hcl Bupivacaine HCl (Marcaine) is a local anesthetic that reduces the flow of sodium in and out of nerves which decreases the initiation and transfer of nerve signals in the area...” NCT03318757
55

Bupivacaine HCl 0.5% 10 mL plus dexamethasone 2 mg for quadriceps sparing femoral nerve block and bupivacaine HCl 0.25% plus dexamethasone 2 mg for posterior knee compartment...” NCT02624856

“A novel bupivacaine implant, XARACOLL (bupivacaine HCl), is Food and Drug Administration approved for treatment of acute postsurgical pain following adult inguinal herniorrhaphy.” PMID 37076252 Apr 2023

“Immediately prior to surgical wound closure, participants randomized to the bupivacaine arm will be injected with bupivacaine HCl along the closure site.” NCT04260854

“The random number generator feature in REDcap will be used to randomly assign subjects to receive the standard Bupivacaine HCl ACB or the Exparel ACB.” NCT04764916

“Evaluate the efficacy of intercostal nerve block using SKY0402 compared to epidural bupivacaine HCl in subjects undergoing posterolateral thoracotomy.” NCT00807209

“The local anesthetic (LA) used for the PECS II or serratus plane blocks will be a 0.5% bupivacaine HCL, not to exceed 2.5mg/kg or up to 150mg.” NCT03743194

“Bilateral abdominal Lap-TAP block injection near incision site with 0.25% Bupivacaine HCl (30cc) with 30ml being injected bilaterally.” NCT04655339

“with a solution composed of 50 ml Bupivacaine Hcl 0.25% (Bucain® Weimer pharma, for Actavis Group PTC) and 0.5 mg of epinephrine Hcl” NCT05806307

bupivacaine HCl 80 mg, morphine 4 mg, epinephrine 300 micrograms, clonidine 100 micrograms, cefuroxime 750 mg, and normal saline” NCT00492973

“Marcaine® (bupivacaine HCl) 0,5% and Xylocaine® (Lidocaine HCL) 2% = 2:1 Given in Femoropopliteal block group (Group F)” NCT06702202

“One side with Marcaine (Bupivacaine HCL) 0.5% 5 mg / mL Injection,opposite side without injection of any anesthetic.” NCT03479996

Bupivacaine HCL 0.25% Injection plus Dexmedetomidine 1micro/kg Dose: 1 mL/kg (milliliter per kilogram body weight)” NCT05919173

“Group 1 will be given an IPSA block using 10 mL of EXPAREL mixed with 10 mL of bupivacaine HCl 0.5%.” NCT07584915

“single 1.6 mL dose of bupivacaine HCl 7.5 mg/mL within 2 hours prior to the surgical procedure” NCT02284386

“standard of care medication-bupivacaine HCl 0.25% (2.5 mg/mL) with epinephrine (5 mcg/mL) i.m.” NCT03420638

“Single dose of bupivacaine HCl (100 mg) administered locally into the surgical wound.” NCT01203644

“300-mg bupivacaine (three INL-001 100-mg bupivacaine HCl collagen-matrix implants)” PMID 30467808 Nov 2018

“Standard of care will consist of 0.25% Bupivacaine HCl TLIP injection 30mL” NCT06350981

Bupivacaine HCl without epinephrine, 75 mg by injection” NCT03237481

“Group B (Bupivacaine HCL plus supraclavicular block)” NCT04540848

Bupivacaine HCl 0.025 % in 10+10 ML Injection” NCT04947007

Bupivacaine HCl 0.5% Injectable Solution” NCT05751421

Bupivacaine HCl 0.5% Injectable Solution” NCT05734625

Bupivacaine HCl 0.5 % in 20 ML Injection” NCT04900116

Bupivacaine HCl collagen-matrix implant” NCT03262688

“15 ml Bupivacaine Hcl 0.25% injection” NCT07255768

Bupivacaine HCl without epinephrine” NCT03015532

“0.125% Bupivacaine HCL @ 4-5 ml/h” NCT01838707

Bupivacaine Hcl 0.25% ESP block” NCT04313764

“0.25% bupivacaine HCl 2 mg/kg” NCT06271265

Bupivacaine HCl via injection” NCT02689258

Bupivacaine Hcl 0.25% Inj_#1” NCT07590752

Bupivacaine HCl, 50 mg/10 mL” NCT05517486

Bupivacaine Hcl 0.5% Inj_#2” NCT05893771

Bupivacaine Hcl 0.25% Inj” NCT03538496

Bupivacaine Hcl 0.75% Inj” NCT06465992

“Drug: +/- Bupivacaine HClNCT03974932

Bupivacaine Hcl 0.25% Inj” NCT04221880

Bupivacaine Hcl 0.5% Inj” NCT05998551

Bupivacaine Hcl 0.5% Inj” NCT06575010

Bupivacaine HCl implant” NCT02232178

“0.25 % Bupivacaine HClNCT05603832

“0.5% Bupivacaine HClNCT06937385

Bupivacaine HCLNCT05972018

Bupivacaine HClNCT02232178

NCT00744848

NCT03705065

NCT00745290

NCT02574520

NCT00485433

NCT00485693

NCT04232306

NCT00813111

NCT02274870

NCT03922048

Known as Bupivacaine HCl (Marcaine 0.25% with epinephrine 1:200,000) Bupivacaine HCl (Marcaine 0.25% with epinephrine 1:200,000)NCT00485693
Known as Bupivacaine Hcl 0.25% Inj “Drug: Bupivacaine Hcl 0.25% InjNCT03541941
Known as Bupivacaine heavy “Spinal anesthesia with Bupivacaine heavy 40 mg and Morphine 250 micro grams will be given to patient in addition to the routine general anesthesia before the start of surgery” NCT03013075
Known as Bupivacaine Hydrochloride Bupivacaine Hydrochloride is 2-Piperidinecarboxamide, 1-butyl-N-(2,6-dimethylphenyl)-monohydrochloride, monohydrate, a white crystalline powder that is freely soluble in 95...” NCT03672500
111

“This is a prospective, single-institution, parallel-group, single-blinded, randomized-controlled, two-arm, effectiveness study comparing bupivacaine liposomal injectable...” NCT02111746

“Initiated dose of 0.3ml/kg of Bupivacaine Hydrochloride 1.25mg/ml and Fentanyl Citrate 2 micrograms/ml was administered then continued PCA (Perfusor space pump,Germany)with...” NCT03242668

Bupivacaine Hydrochloride is indicated for the production of local or regional anesthesia or analgesia for surgery, dental and oral surgery procedures, diagnostic and...” NCT03176459

“Patients will receive a pre-closure local infiltration of 266 mg liposomal bupivacaine (20 mL for single-level surgery; 30 mL for two-level surgery) combined with 25 mg...” NCT07171125

“A total of 9 ml of Bupivacaine-Hydrochloride (Marcaine) 0.5%, or Sodium-Chloride 0.9%, as a placebo, were injected subcutaneously to the trocar sites (3 ml to each trocar...” PMID 33420214 Jan 2021

“Solution of: 150mg of Bupivacaine Hydrochloride 0.25% expanded with 60cc of Normal Saline (Nacl0.9%) administered intraoperatively through a transversus abdominis plane (TAP) block” NCT03541941

“We implanted four XaraColl implants each containing 50 mg of bupivacaine hydrochloride (200 mg total dose) in ten men undergoing laparoscopic inguinal or umbilical hernioplasty.” PMID 23390367 Feb 2013

“10 mL of 0.25% Bupivacaine Hydrochloride (HCL) will be injected through the anterolateral portal while the additional 10 mL will be injected through the mid-anterior portal.” NCT04353414

“After mesh placement, a long-acting local anesthetic (bupivacaine hydrochloride, 0.50%) or placebo (0.9% normal saline) was injected between the mesh and the peritoneum.” PMID 26154700 Sep 2015

“Lidocaine and bupivacaine hydrochloride (HCl) are the most commonly used drugs for wound infiltration during laparoscopic surgery for post-operative pain control.” NCT02352922

“Patients will receive either 3 XaraColl Bupivacaine Implants each containing 100 mg of bupivacaine hydrochloride, for a 300 mg total dose; or 3 placebo-sponges.” NCT02525133

“Patients will receive either 3 XaraColl Bupivacaine Implants each containing 100 mg of bupivacaine hydrochloride, for a 300 mg total dose; or 3 placebo-sponges.” NCT02523599

“The 40 mL 0.25% Bupivacaine hydrochloride (100 mg, normal saline dilution) for the Bupivacaine hydrochloride group.” NCT07458256

“Injection with10 mls 0.5% bupivacaine hydrochloride and 20 mg of Depomedrol 40 mls saline (NaCl) around the tendon” NCT02417987

“Part A participants were randomized 1:1:1 to LB 266 mg, LB 133 mg, or bupivacaine hydrochloride 50 mg (BUPI).” PMID 38340677 Feb 2024

“For Group I, 7.5 mg(1.5 mL) of 0.5% hyperbaric bupivacaine hydrochloride will be drawn in a 3 mL BD syringe.” NCT05993975

“7.5 mg Bupivacaine hydrochloride (0.5% heavy Marcaine) will be used on spinal anesthesia. (each group)” NCT06293404

“different doses (100 mg and 200 mg of bupivacaine hydrochloride; study 1 and 2, respectively).” PMID 22792007 Jun 2012

“20 ml Bupivacaine hydrochloride 0.25% administered on each side as bilateral TQL blocks” NCT03956966

Bupivacaine Hydrochloride 0.25% Injection. Paracetamol 650mg. Orphenadrine 50mg.” NCT04835116

“20 ml of 0.25% bupivacaine hydrochloride. (Marcaine, 25% vial, Astra Zeneca)” NCT04538391

“20 mL of 0.25% bupivacaine hydrochloride (50 mg, diluted in normal saline)” NCT07458295

“20 mL of 0.25% bupivacaine hydrochloride (50 mg, diluted in normal saline)” NCT07458282

“Injection of Bupivacaine Hydrochloride 0.5% near the stellate ganglion.” NCT04727229

“10 cc of 0.25% bupivacaine hydrochloride with 1:200,000 epinephrine” NCT06450028

“50 mg bupivacaine hydrochloride 0.5% (AstraZeneca, Cenexi, France)” NCT05324995

“LB and bupivacaine hydrochloride via erector spinae plane blocks” NCT05730920

Bupivacaine Hydrochloride 0.25% Injection Solution [MARCAINE]” NCT04269460

“Drug: Bupivacaine Hydrochloride 0.25% Injection Solution” NCT03283436

Bupivacaine Hydrochloride 0.25% Injection Solution_#2” NCT05062356

Bupivacaine Hydrochloride 0.5% Injection Solution_#4” NCT03225313

“0.375% Bupivacaine Hydrochloride 10ml was injected.” NCT07587203

Bupivacaine Hydrochloride 0.75% Injection Solution” NCT03967288

Bupivacaine Hydrochloride 0.25% Injection Solution” NCT05919173

“plain bupivacaine hydrochloride 0.5% intrathecally” NCT01582607

Bupivacaine hydrochloride 0.5% (Marcaine, Pfizer)” NCT04361513

bupivacaine hydrochloride (HCl) 125 mg injection” PMID 32561266 May 2020

Bupivacaine Hydrochloride, Spinal” NCT03434951

“Drug: Bupivacaine HydrochlorideNCT06146842

“Drug: Bupivacaine hydrochlorideNCT02630160

“Drug: Bupivacaine HydrochlorideNCT07601750

“Drug: Bupivacaine HydrochlorideNCT02953210

“Drug: Bupivacaine HydrochlorideNCT03854344

“Drug: Bupivacaine HydrochlorideNCT07512635

“Drug: Bupivacaine HydrochlorideNCT03638960

“Drug: Bupivacaine HydrochlorideNCT02962024

“Drug: Bupivacaine HydrochlorideNCT04897841

“Drug: Bupivacaine HydrochlorideNCT04293809

“Drug: Bupivacaine HydrochlorideNCT05499689

Bupivacaine hydrochlorideNCT04766996

Bupivacaine hydrochlorideNCT04368364

NCT03259243

NCT05549895

NCT00001088

NCT05502146

NCT02022722

NCT06577233

NCT07442539

NCT06502262

NCT04764916

NCT00879164

NCT04618146

NCT06088082

NCT06704698

NCT04244097

NCT04532775

NCT04613830

NCT06423339

NCT02892500

NCT03955458

NCT05524038

NCT05751291

NCT04173611

NCT04998071

NCT04700228

NCT06641206

NCT04648332

NCT05543694

NCT04778267

NCT03360214

NCT04920994

NCT05381389

NCT04921007

NCT03712111

NCT03599089

NCT04814537

NCT03164096

NCT03907033

NCT03098420

NCT06799845

NCT05109312

NCT06109415

NCT04606836

NCT06109428

NCT05666076

NCT07667439

NCT05038007

NCT05216211

NCT06588907

NCT06229054

NCT03326180

NCT04928352

NCT03792906

NCT03270514

NCT04260854

NCT03023982

NCT06003933

NCT03789318

NCT04785625

NCT06077422

NCT04785638

Known as Bupivacaine Hydrochloride (HCl) “A Multicenter, Randomized, Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Analgesic Effect of the INL-001 Bupivacaine Hydrochloride (HCl)...” NCT03262688
1

NCT04278846