drugset / Trial / NCT07216586

Zynrelef Versus Adductor Canal Block

NCT07216586

Phase 4 Not yet recruiting 120 enrolled University of Miami
RandomizedParallel-groupOpen-labelTreatment

Summary

To compare postoperative MME consumption 72 hours after TKA in patients receiving intraoperative periarticular HTX-011 (Zynrelef) instillation versus adductor canal block.

Timeline

Start
2027-01
Primary completion
2028-01
Completion
2028-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Bupivacaine Other / unclassified 400 mg Other
Subject Meloxicam Small molecule 12 mg Other
Comparator Ropivacaine Other / unclassified 0.5 % Other
Comparator Ropivacaine Other / unclassified 30 ml Other

Indications