Erector Spinae Plane Block With Bupivacaine for Medical Thoracoscopy

Phase 3 Terminated 33 enrolled Icahn School of Medicine at Mount Sinai

RandomizedParallel-groupTriple-blindTreatment

Summary

PlAcebo versus erector spINae pLane block for mEdical ThoracoScopy Study (PAINLESS). This is a prospective triple-blind, randomized controlled trial that evaluates the efficacy of erector spinae plane block (ESPB) with Bupivacaine in reducing pain after medical thoracoscopy (MT) in addition to monitored anesthesia care vs monitored anesthesia care alone.

Timeline

Start: 2024-03-28
Primary completion: 2025-03-19
Completion: 2025-03-20

Publications

Luebbert E, Salguero BD, Joy G, Salman S, Lo Cascio CM, Echevarria G, Chaddha U, Pai B H P. Benefits of Using Peripheral Nerve Blocks for Medical Thoracoscopy: A Retrospective Analysis. J Bronchology Interv Pulmonol. 2025 Mar 18;32(2):e1006. doi: 10.1097/LBR.0000000000001006. eCollection 2025 Apr 1.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Bupivacaine	Other / unclassified	0.5 %	—
Subject	Bupivacaine	Other / unclassified	30 ml	—

Erector Spinae Plane Block With Bupivacaine for Medical Thoracoscopy

Summary

Timeline

Publications

Drugs

Indications