drugset / Trial / NCT02030717

Randomized Study of Spinal Anesthesia Compared With Traditional Epidural Anesthesia Concerning Peroperative and Postoperative Pain After Open Nephrectomy in Patients With Renal Cell Carcinoma

NCT02030717

Phase 2/3 Completed 120 enrolled Umeå University University Hospital, Umeå · collab
RandomizedParallel-groupOpen-labelTreatment

Summary

The study aim to study whether spinal anesthesia (using: bupivacain, morfin och klonidin) can be better than epidural anesthesia during and after open surgery for renal cell carcinoma. Per- and postoperative pain after spinal anesthesia with klonidin can be reduced and, thus, shorten the hospital stay and rehabilitation of the patients.

Timeline

Start
2012-02
Primary completion
2015-05
Completion
2015-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Bupivacaine Other / unclassified 1 mg/ml Intrathecal
Subject Bupivacaine Other / unclassified 12 mg Intrathecal
Subject Clonidine Other / unclassified 45 ug Intrathecal
Subject Clonidine Other / unclassified 60 ug Intrathecal
Subject Clonidine Other / unclassified 75 ug Intrathecal
Comparator Epinephrine Other / unclassified 1 ug/ml Other
Comparator Fentanyl Other / unclassified 1 ug/ml Other
Subject Morphine Other / unclassified 160 ug Intrathecal

Indications