drugset / Trial / NCT02030717
Randomized Study of Spinal Anesthesia Compared With Traditional Epidural Anesthesia Concerning Peroperative and Postoperative Pain After Open Nephrectomy in Patients With Renal Cell Carcinoma
RandomizedParallel-groupOpen-labelTreatment
Summary
The study aim to study whether spinal anesthesia (using: bupivacain, morfin och klonidin) can be better than epidural anesthesia during and after open surgery for renal cell carcinoma. Per- and postoperative pain after spinal anesthesia with klonidin can be reduced and, thus, shorten the hospital stay and rehabilitation of the patients.
Timeline
- Start
- 2012-02
- Primary completion
- 2015-05
- Completion
- 2015-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bupivacaine | Other / unclassified | 1 mg/ml | Intrathecal |
| Subject | Bupivacaine | Other / unclassified | 12 mg | Intrathecal |
| Subject | Clonidine | Other / unclassified | 45 ug | Intrathecal |
| Subject | Clonidine | Other / unclassified | 60 ug | Intrathecal |
| Subject | Clonidine | Other / unclassified | 75 ug | Intrathecal |
| Comparator | Epinephrine | Other / unclassified | 1 ug/ml | Other |
| Comparator | Fentanyl | Other / unclassified | 1 ug/ml | Other |
| Subject | Morphine | Other / unclassified | 160 ug | Intrathecal |