Drugs / Fentanyl
last change 3 days ago re-read 2 minutes ago

Fentanyl

Other / unclassified targets OPRM1 via activation

Developed for
cancer · chronic pain syndrome · neuropathy, painful · osteoarthritis · delirium · chronic obstructive pulmonary disease · gallbladder disorder · respiratory failure
+65 more · abscess · anxiety · cancer of unknown primary site · pain agnosia · sickle cell disease · bone neoplasm · cardiac rhythm disease · complex regional pain syndrome · obstetric disorder · obstructive sleep apnea syndrome · osteoarthritis, knee · postpartum depression · tonsillitis · acne · acute lung injury · acute pancreatitis · bone pain, periodic · cardiac valvular defect · cataract · childhood malignant neoplasm · congestive heart failure · critical illness polyneuropathy · diabetic neuropathy · disease of bone structure · headache disorder · heroin dependence · hypertensive disorder · migraine disorder · neurological pain disorder · newborn respiratory distress syndrome · opiate dependence · peripheral neuropathy · postherpetic neuralgia · pregnancy disorder · rheumatoid arthritis · substance withdrawal syndrome · tooth hard tissue disease · uterine disorder · acute respiratory distress syndrome · acute respiratory failure · benign shuddering attacks · bone disorder · cleft lip/palate · congenital pulmonary airway malformation · dental caries · female breast carcinoma · female infertility due to oocyte meiotic arrest · gingivitis · interstitial lung disease · musculoskeletal system disorder · outlet dysfunction constipation · pectus excavatum · peripheral arterial occlusive disease 1 · pneumonia · pregnancy disorder with abortive outcome · pulpitis · reactive airway disease · smooth surface dental caries · snakebite envenomation · ST-elevation myocardial infarction · subarachnoid hemorrhage · ulcer of lower limbs · urinary tract obstruction · vascular hemostatic disease · vertebral disorder
Investigated by
Cephalon · INSYS Therapeutics Inc · Assiut University · M.D. Anderson Cancer Center · Alza Corporation · Yonsei University
+321 more · Janssen Pharmaceutical K.K. · Ain Shams University · Kyowa Kirin, Inc. · Seoul National University Hospital · Cairo University · Janssen-Cilag Ltd.,Thailand · Johns Hopkins University · Nycomed · PriCara, Unit of Ortho-McNeil, Inc. · Tanta University · ZARS Pharma Inc. · Asan Medical Center · BioDelivery Sciences International · Brigham and Women's Hospital · Columbia University · Depomed · Dow University of Health Sciences · Janssen Korea, Ltd., Korea · Janssen Pharmaceutica N.V., Belgium · Lee's Pharmaceutical Limited · National Cancer Institute (NCI) · Rambam Health Care Campus · Ruijin Hospital · University of British Columbia · University of Texas Southwestern Medical Center · Ankara City Hospital Bilkent · Archimedes Development Ltd · Azienda Sanitaria dell'Alto Adige · Benha University · Beth Israel Deaconess Medical Center · Canadian Institutes of Health Research (CIHR) · Cedars-Sinai Medical Center · Changhai Hospital · Ciusss de L'Est de l'Île de Montréal · Danish Pain Research Center · Duke University · Egymedicalpedia · Helwan University · Incline Therapeutics, Inc. · Janssen Research & Development, LLC · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. · KK Women's and Children's Hospital · Karolinska Institutet · Loyola University · Mahidol University · Mayo Clinic · McGill University Health Centre/Research Institute of the McGill University Health Centre · Medical University of Graz · Meir Medical Center · Minia University · Montefiore Medical Center · National Institute of General Medical Sciences (NIGMS) · National Institute on Drug Abuse (NIDA) · Oslo University Hospital · RenJi Hospital · Samuel Lunenfeld Research Institute, Mount Sinai Hospital · Seoul National University Bundang Hospital · Shandong University · Shanghai Pulmonary Hospital, Shanghai, China · Shanghai Zhongshan Hospital · St. Justine's Hospital · St. Olavs Hospital · Takeda · The Affiliated Hospital of Qingdao University · The First Affiliated Hospital with Nanjing Medical University · United States Department of Defense · University Hospital, Basel, Switzerland · University of California, San Francisco · University of Jordan · University of Oslo · Walter Reed National Military Medical Center · YM BioSciences · Zulekha Hospitals · Academic Medical Center - University of Amsterdam · all 327 on the full record

Regulatory milestones approvals, filings & regulatory actions · 11 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Label expansions (3) US (FDA) DURAGESIC-100 2003-05-20 – 2018-01-24 fda.gov
Label expansion US (FDA) IONSYS 2015-04-30 fda.gov
Label expansion US (FDA) FENTORA 2013-02-21 fda.gov
Refused (EMA) EU (EMA) Ionsys 2008-07-25 europa.eu
Label expansion US (FDA) ACTIQ 2007-02-07 fda.gov
Approved EU (EMA) Ionsys 2006-01-24 europa.eu
Label expansions (2) US (FDA) FENTANYL 1995-10-30 – 1996-05-20 fda.gov
Approved US (FDA) SUBLIMAZE PRESERVATIVE FREE 1968-02-19 fda.gov

Trials 396 · started per year

today
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EU approved 2006
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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 05 trials
Phase 0 NCT06561672 Sep 2024 → Mar 2025 overdue Zagazig University Enrolling by invitation No outcome recorded
Phase 0 NCT06435949 Jul 2024 → Jun 2026 Ruijin Hospital Unknown No outcome recorded
Phase 0 NCT05579509 Oct 2022 → May 2024 Brigham and Women's Hospital Completed No outcome recorded
Phase 0 NCT02209610 Jul 2015 → Jan 2017 heart failure VA Office of Research and Development Completed No outcome recorded
Phase 0 NCT01853449 Jun 2013 → Aug 2014 McGill University Completed No outcome recorded
Phase 125 trials
Phase 1 NCT06953453 Sep 2025 → Jul 2026 overdue cancer Lee's Pharmaceutical Limited Recruiting No outcome recorded
Phase 1 NCT06281951 Apr 2024 → Jun 2027 expected University Hospital, Rouen Recruiting No outcome recorded
Phase 1 NCT05429567 Mar 2021 → Feb 2022 Egymedicalpedia Completed No outcome recorded
Phase 1 NCT04062123 Jul 2020 → Apr 2024 Keith M Vogt Completed No outcome recorded
Phase 1 NCT04823390 Sep 2019 → Feb 2021 Cairo University Completed No outcome recorded
Phase 1 NCT04011098 Jul 2019 → Nov 2020 obstetric disorder University of Saskatchewan Terminated No outcome recorded
Phase 1 NCT03824314 May 2019 → Jan 2020 Mohamed Abdelrady Mohamed Completed No outcome recorded
Phase 1 NCT03747341 Mar 2018 → Jan 2019 substance-related disorder Indivior Inc. Completed No outcome recorded
Phase 1 NCT02641340 Jan → Mar 2016 INSYS Therapeutics Inc Completed No outcome recorded
Phase 1 NCT02608320 Nov 2015 → Apr 2016 Janssen Research & Development, LLC Completed No outcome recorded
Phase 1/29 trials
Phase 1/2 NCT07112430 Sep 2026 → Mar 2028 expected retinopathy of prematurity Marsha Campbell-Yeo Not yet recruiting No outcome recorded
Phase 1/2 NCT07672301 Mar 2026 → Jun 2027 expected University of Chicago Recruiting No outcome recorded
Phase 1/2 NCT06031883 Feb 2023 → Dec 2024 Minia University Completed No outcome recorded
Phase 1/2 NCT05037539 Jun → Dec 2021 bone pain, periodic Department of Medical Services Ministry of Public Health of Thailand Completed No outcome recorded
Phase 1/2 NCT04713189 Mar → Dec 2021 Lee's Pharmaceutical Limited Unknown No outcome recorded
Phase 1/2 NCT04136548 Jun 2019 → Nov 2020 University of Texas Southwestern Medical Center Completed No outcome recorded
Phase 1/2 NCT01515566 Apr 2012 → Apr 2013 M.D. Anderson Cancer Center Completed No outcome recorded
Phase 1/2 NCT01248611 Jan → May 2011 cancer, chronic pain syndrome St. Olavs Hospital Completed No outcome recorded
Phase 1/2 NCT00685295 Aug 2008 → Feb 2009 Massachusetts General Hospital Completed No outcome recorded
Phase 230 trials
Phase 2 NCT07224620 Nov 2025 → May 2026 Beth Israel Deaconess Medical Center Completed No outcome recorded
Phase 2 NCT05057689 Sep → Oct 2025 acute stress disorder, anxiety Nationwide Children's Hospital Withdrawn No outcome recorded
Phase 2 NCT06531759 Sep 2024 → Sep 2025 overdue Assiut University Not yet recruiting No outcome recorded
Phase 2 NCT05367336 Aug 2022 → Feb 2025 qualitative platelet defect Corewell Health South Terminated No outcome recorded
Phase 2 NCT05531422 Oct 2021 → Mar 2023 Lee's Pharmaceutical Limited Completed No outcome recorded
Phase 2 NCT04204967 Feb 2021 → Apr 2024 respiratory failure Fondazione Policlinico Universitario Agostino Gemelli IRCCS Completed No outcome recorded
Phase 2 NCT03809455 Feb 2020 → Feb 2022 UNICANCER Withdrawn No outcome recorded
Phase 2 NCT03293927 Apr 2018 → Jul 2019 delirium Duke University Withdrawn No outcome recorded
Phase 2 NCT03071744 Mar 2017 → Mar 2018 bone neoplasm Joseph Ma Terminated No outcome recorded
Phase 2 NCT02915978 Dec 2016 → Feb 2017 INSYS Therapeutics Inc Completed No outcome recorded
Phase 2/312 trials
Phase 2/3 NCT06799442 Mar → Dec 2025 overdue Assiut University Not yet recruiting No outcome recorded
Phase 2/3 NCT05145543 Dec 2021 → Mar 2022 Assiut University Unknown No outcome recorded
Phase 2/3 NCT04971759 Dec 2019 → Dec 2020 Assiut University Completed No outcome recorded
Phase 2/3 NCT04004117 Jul → Dec 2019 chronic obstructive pulmonary disease McGill University Health Centre/Research Institute of the McGill University Health Centre Terminated No outcome recorded
Phase 2/3 NCT02489019 Feb 2018 → Jul 2020 hypotensive disorder Loyola University Unknown No outcome recorded
Phase 2/3 NCT03260283 Aug 2017 → Nov 2018 Saint Savvas Anticancer Hospital Completed No outcome recorded
Phase 2/3 NCT03167905 Jun 2017 → Jul 2021 overdue postpartum depression KK Women's and Children's Hospital Active not recruiting No outcome recorded
Phase 2/3 NCT02597478 Jan 2016 → Sep 2018 cancer of unknown primary site M.D. Anderson Cancer Center Completed No outcome recorded
Phase 2/3 NCT02617199 Nov 2015 → Dec 2016 acute pancreatitis Hospital General Naval de Alta Especialidad - Escuela Medico Naval Unknown No outcome recorded
Phase 2/3 NCT02298582 Dec 2014 → Oct 2017 University Hospital, Grenoble Completed No outcome recorded
Phase 382 trials
Phase 3 NCT07076368 Oct 2025 → Jul 2026 overdue pregnancy disorder University of California, San Francisco Recruiting No outcome recorded
Phase 3 NCT06464146 Feb 2025 → Feb 2028 expected Assistance Publique - Hôpitaux de Paris Recruiting No outcome recorded
Phase 3 NCT07019805 Sep 2024 → Mar 2025 acute hypotension Indonesia University Completed No outcome recorded
Phase 3 NCT06590870 Aug 2024 → Feb 2025 Mount Sinai Hospital, Canada Completed No outcome recorded
Phase 3 NCT06051227 Jan 2024 → Mar 2026 overdue Academic Medical Center - University of Amsterdam Recruiting No outcome recorded
Phase 3 NCT05491187 Sep 2022 → Apr 2023 Tribhuvan University Teaching Hospital, Institute Of Medicine. Completed No outcome recorded
Phase 3 NCT05137184 Nov 2021 → Apr 2023 Oslo University Hospital Completed No outcome recorded
Phase 3 NCT04621110 Jun → Sep 2021 childhood malignant neoplasm University of Sao Paulo General Hospital Unknown No outcome recorded
Phase 3 NCT04188418 Oct 2020 → Aug 2027 expected cancer, hematopoietic and lymphoid cell neoplasm M.D. Anderson Cancer Center Active not recruiting No outcome recorded
Phase 3 NCT04533243 Sep 2020 → Aug 2022 Fujian Cancer Hospital Unknown No outcome recorded
Phase 4117 trials
Phase 4 NCT07684365 Aug 2026 → Dec 2027 expected Beth Israel Deaconess Medical Center Not yet recruiting No outcome recorded
Phase 4 NCT07670052 Aug 2026 → Jun 2027 expected Assiut University Not yet recruiting No outcome recorded
Phase 4 NCT07556523 Mar 2026 → Apr 2028 expected aortic valve stenosis David Lyubashevsky Recruiting No outcome recorded
Phase 4 NCT07116564 Aug 2025 → Aug 2026 overdue Aga Khan University Recruiting No outcome recorded
Phase 4 NCT06793358 Jul 2025 → Feb 2026 Indiana University Withdrawn No outcome recorded
Phase 4 NCT06696586 Jul 2025 → Dec 2026 expected Assiut University Not yet recruiting No outcome recorded
Phase 4 NCT06763705 Jun → Dec 2025 Qassim Health Cluster Completed No outcome recorded
Phase 4 NCT06752629 Jan 2025 → Jan 2026 overdue gallbladder disorder Assiut University Not yet recruiting No outcome recorded
Phase 4 NCT06720506 Jan 2025 → Jan 2026 overdue Assiut University Not yet recruiting No outcome recorded
Phase 4 NCT06722963 Jan 2025 → Jan 2026 overdue Assiut University Not yet recruiting No outcome recorded
Show all 117 trials opens the full record — a long page
Phase not applicable116 trials
NCT07435493 Nov 2026 expected adenoid hypertrophy, obstructive sleep apnea syndrome Ain Shams University Not yet recruiting No outcome recorded
NCT07610408 Jun → Sep 2026 expected Ankara Etlik City Hospital Recruiting No outcome recorded
NCT07347886 Jan → Jul 2026 overdue cataract Istanbul University - Cerrahpasa Not yet recruiting No outcome recorded
NCT07258628 Oct 2025 → Jan 2026 cardiac rhythm disease, hypertensive disorder Ankara City Hospital Bilkent Completed No outcome recorded
NCT07310524 Sep → Nov 2025 Muhammad Rahman Efendi Nasution Completed No outcome recorded
NCT07166666 Sep 2025 → Sep 2026 expected Oman Medical Speciality Board Not yet recruiting No outcome recorded
NCT07114263 Aug 2025 → Feb 2026 overdue Tanta University Not yet recruiting No outcome recorded
NCT07062601 Jul → Nov 2025 overdue tonsillitis Anqing Municipal Hospital Not yet recruiting No outcome recorded
NCT06779968 Jan → May 2025 overdue Xiaguang Duan Not yet recruiting No outcome recorded
NCT07141589 Aug 2024 → Nov 2025 overdue Cairo University Recruiting No outcome recorded
Show all 116 trials opens the full record — a long page
Also used as a comparator or background therapy in 727 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 015 trials
Phase 0 NCT07711522 Background Aug 2026 → Jul 2027 expected Istanbul Medipol University Hospital Not yet recruiting No outcome recorded
Phase 0 NCT07211399 Comparator Jul 2026 → Dec 2030 substance-related disorder Jacques E. Chelly Withdrawn No outcome recorded
Phase 0 NCT07040163 Comparator Mar 2025 → Feb 2026 overdue CAMC Health System Active not recruiting No outcome recorded
Phase 0 NCT05824338 Comparator Aug 2024 → Jul 2025 overdue Fraser Health Recruiting No outcome recorded
Phase 0 NCT07190625 Comparator Dec 2023 → Mar 2026 overdue Ain Shams University Recruiting No outcome recorded
Phase 122 trials
Phase 1 NCT07332130 Comparator Dec 2025 → Jan 2026 overdue Minia University Hospital Not yet recruiting No outcome recorded
Phase 1 NCT06917898 Comparator Apr 2025 → Apr 2026 overdue Makassed General Hospital Active not recruiting No outcome recorded
Phase 1 NCT06318546 Comparator Apr → Aug 2024 benign shuddering attacks Ain Shams University Completed No outcome recorded
Phase 1 NCT06834854 Comparator Mar → Aug 2024 Ain Shams University Completed No outcome recorded
Phase 1 NCT06951230 Comparator Feb → Aug 2024 Ain Shams University Completed No outcome recorded
Phase 1/211 trials
Phase 1/2 NCT07443254 Background Mar 2026 → Apr 2027 expected CAMC Health System Recruiting No outcome recorded
Phase 1/2 NCT07034950 Comparator Jun 2025 → Jun 2028 expected liver cancer The First Affiliated Hospital of Xiamen University Active not recruiting No outcome recorded
Phase 1/2 NCT06126991 Background Jan → Dec 2024 Ruijin Hospital Unknown No outcome recorded
Phase 1/2 NCT04686448 Comparator Jan → Apr 2021 Zagazig University Unknown No outcome recorded
Phase 1/2 NCT03903367 Comparator May → Dec 2019 Beni-Suef University Unknown No outcome recorded
Phase 247 trials
Phase 2 NCT07588802 Comparator Jul 2026 → Apr 2027 expected Massachusetts General Hospital Not yet recruiting No outcome recorded
Phase 2 NCT07459166 Comparator May → Jul 2026 overdue acute opioid poisoning Clear Scientific, Inc. Recruiting No outcome recorded
Phase 2 NCT07443085 Comparator Feb 2026 → Jul 2027 expected delirium Benha University Recruiting No outcome recorded
Phase 2 NCT07510217 Comparator Aug 2024 → Dec 2025 Tanta University Completed No outcome recorded
Phase 2 NCT06326944 Comparator Apr → Sep 2024 Kasr El Aini Hospital Completed No outcome recorded
Phase 2/320 trials
Phase 2/3 NCT06382831 Comparator Jun → Aug 2024 Indonesia University Unknown No outcome recorded
Phase 2/3 NCT07241351 Comparator Mar → Nov 2024 Ain Shams University Completed No outcome recorded
Phase 2/3 NCT07148882 Comparator Feb → Sep 2024 Ain Shams University Completed No outcome recorded
Phase 2/3 NCT05693675 Background Oct 2023 → Jul 2024 The University of Texas Health Science Center, Houston Withdrawn No outcome recorded
Phase 2/3 NCT06394375 Comparator Jul → Oct 2023 Indonesia University Completed No outcome recorded
Phase 362 trials
Phase 3 NCT07565870 Comparator Jul → Dec 2026 expected Alexandre P. Joosten Not yet recruiting No outcome recorded
Phase 3 NCT07299630 Background Dec 2025 → May 2026 Ain Shams University Completed No outcome recorded
Phase 3 NCT07120763 Comparator Aug 2025 → Aug 2026 overdue State University of New York at Buffalo Recruiting No outcome recorded
Phase 3 NCT07165262 Comparator Aug 2025 → Mar 2027 expected brain neoplasm, epilepsy Children's Cancer Hospital Egypt 57357 Active not recruiting No outcome recorded
Phase 3 NCT06873906 Comparator Mar 2025 → Mar 2026 overdue heart septal defect Ain Shams University Not yet recruiting No outcome recorded
Phase 4254 trials
Phase 4 NCT07637279 Comparator Nov 2026 → Jun 2028 expected polyp of large intestine Karolinska Institutet Not yet recruiting No outcome recorded
Phase 4 NCT07650552 Comparator Sep 2026 → Aug 2028 expected apnea of prematurity, newborn respiratory distress syndrome, pulmonary immaturity UEA - Universidade Do Estado Do Amazonas Not yet recruiting No outcome recorded
Phase 4 NCT07697404 Background Jun 2026 → Jul 2028 expected Huazhong University of Science and Technology Recruiting No outcome recorded
Phase 4 NCT07560501 Comparator Apr → Dec 2026 expected Tribhuvan University Teaching Hospital, Institute Of Medicine. Not yet recruiting No outcome recorded
Phase 4 NCT07334132 Background Apr 2026 → Dec 2029 expected osteoarthritis Region Örebro County Not yet recruiting No outcome recorded
Show all 254 trials opens the full record — a long page
Phase not applicable296 trials
NCT07680400 Comparator Jul → Aug 2026 overdue Bezmialem Vakif University Not yet recruiting No outcome recorded
NCT07640516 Comparator Jul 2026 → Jan 2027 expected Kasr El Aini Hospital Recruiting No outcome recorded
NCT07658521 Background Jul → Dec 2026 expected Ain Shams University Enrolling by invitation No outcome recorded
NCT07636070 Comparator Jun → Aug 2026 overdue urolithiasis murat sahin Not yet recruiting No outcome recorded
NCT07558226 Comparator May 2026 → Nov 2027 expected Fundacio Puigvert Recruiting No outcome recorded
Show all 296 trials opens the full record — a long page

Press releases naming this drug 1 release

DateIssuerRelease
2008-10-20 Teva Branded Pharmaceutical Products R&D, Inc. Teva Announces FDA Approval and Commercial Launch of Fentanyl Transdermal System tevapharm.com

Evidence & citations 129 cited values

Every value below carries the sentence it was read from. 1,131 sources stand behind the page.

FieldValueCited text
Known as fentanyl “The current double-blind, placebo-controlled in-patient study was designed to compare the effects of intravenously delivered fentanyl (0, 0.0625, 0.125, 0.187, and 0.250 mg/70...” PMID 17581533 Jun 2007
1093

“patients whose labor analgesia is maintained using PIEB with low-volume bolus (6.25 mL) of a higher local anesthetic concentration solution (0.1% bupivacaine with fentanyl 2.0...” NCT03553576

“After the surgery: 10 ml 0.25% bupivacaine through epidural catheters before extubation and continuous infusion of 0,1% bupivacaine and 1 µg/ml fentanyl 5 ml/h with...” NCT02622893

“Participants will be induced using lidocaine 1 mg/kg IV, an opioid such a fentanyl (1-2 mcg/kg) IV, followed by 0.6 mg/kg IV rocuronium, and IV propofol with dosage at the...” NCT06029049

“The parturients were randomly assigned to groups receiving either spinal sufentanil (5 µg), epidural sufentanil (20 µg), spinal fentanyl (20 µg) or epidural fentanyl (100 µg),...” PMID 31286476 Jul 2019

“Preservative free 0.5% Hyperbaric bupivacaine (AstraZeneca) 5mg + 25mcg fentanyl for the initial dose will be followed by top up doses of 2.5 mg boluses of 0.5% Hyperbaric...” NCT05897151

“Maintenance of anesthesia will be achieved by isoflurane at an end tidal concentration of 1-1.5% in FiO2 of 0.5, intravenous fentanyl at a dose of 1 µg/kg in incremental...” NCT06873906

“Intraoperative analgesia will be ensured by administering fentanyl 0.5-1 µg/kg as needed, based on clinical signs of inadequate analgesia (e.g., an increase in blood pressure...” NCT07207304

“Intraoperatively, fentanyl in fractional doses of 1-3 µg∙kg-1 were applied if the heart rate (HR; Heart Rate) or mean blood pressure (MBP; Mean Blood Pressure) increased by...” NCT04355468

“The administered anesthetic mixture will include a fixed dose of fentanyl (15 μg), a variable dose of ropivacaine based on the parturient's somatometric characteristics, and a...” NCT07023497

“The patient will be sedated with a combination of midazolam, fentanyl administered intravenously in small boluses until the desired level of sedation is achieved as expressed...” NCT03546088

“1-3 mg IV propofol 0.5 mg/kg IV Rocuronium + Fentanyl 2-3 mcg/kg + Morphine 0.1mg/kg IV Maintenance: Volatile anesthetic + High volume local anesthesia infiltration Bupivacaine...” NCT03176758

“BioDelivery Sciences International, Inc. (BDSI) has developed BioErodible MucoAdhesive (BEMA) Fentanyl, an alternative product to OTFC that does not require the subject to...” NCT00293033

“Induction of anesthesia will be the same for all patients and consist of intravenous anesthetic propofol (2-3 mg/kg), opioid analgesic fentanyl (1-1.5 mcg/kg), and muscle...” NCT05958589

“This study evaluated the long-term effectiveness and tolerability of sublingual fentanyl orally disintegrating tablet (sublingual fentanyl ODT), for the treatment of BTcP in...” PMID 21208151 Jan 2011

“A patient-controlled device prepared with 10 mcg/ ml fentanyl will be attached to all patients with a protocol including a 10 mcg bolus without an infusion dose, a 10-minute...” NCT07278050

Fentanyl group recieve induction and maintenance doses of fentanyl by target controlled infusion in addition of propofol-dexmedetomidine as total intravenous anesthesia for...” NCT06031883

“Intraoperative analgesia using short-acting opioids (e.g., fentanyl and/or hydromorphone) administered at induction and throughout surgery according to clinician judgment and...” NCT07565870

“This typically involves the intravenous (IV) administration of strong opioids such as Fentanyl or Sufentanil to manage the intense pain during the craniotomy (bone flap...” NCT07510217

“A patient-controlled device prepared with 10 mcg/ ml fentanyl will be attached to all patients with a protocol including 10 mcg bolus without infusion dose, 10 min lockout...” NCT05972122

“A patient-controlled device prepared with 10 mcg/ ml fentanyl will be attached to all patients with a protocol including 10 mcg bolus without infusion dose, 10 min lockout...” NCT06546839

Fentanyl IV infusion via PCA (patient controlled analgesia) machine of fentanyl 10 μg/ml, ramosetron 0.3 mg, normal saline, total 100 ml, infusion rate 1 ml/hr, 1 ml bolus and...” NCT04061057

“JNS020QD is a transdermal system in which fentanyl base is incorporated directly into a single layer of pressure-sensitive high polymerized adhesive, and is changed once a day...” NCT01493245

“Standard of Care analgosedation of choice using propofol, fentanyl, dexmedetomidine, morphine, hydromorphone, midazolam, or lorazepam administered according to the...” NCT06429657

“In the EVE group, 1 mL of a mixture containing a combination of 10 µg fentanyl and 0.25% isobaric bupivacaine was injected into the intrathecal region via a 25-G 120 mm...” PMID 40068075 Mar 2025

“This trial evaluated the efficacy and long-term tolerability of a sublingual formulation of the fast-acting opioid fentanyl, for the treatment of BTcP in opioid-tolerant...” PMID 19814586 Dec 2009

“Patients in control group will receive a conventional GA with fentanyl 2µg/kg given during induction of anesthesia and one fourth of initial dose of fentanyl will be given over...” NCT07213687

Fentanyl 25 mcg intravenous push (IVP) every 5 min up to 4 doses hourly as needed to target pain score for the study design duration (28 days) or for the duration of mechanical...” NCT02219659

“Patients in the TIVA group had anesthesia induced with propofol 2 mg/kg , fentanyl 1 ug/kg and maintained with propofol. 200 ug/kg/min, fentanyl 0.1ug/kg/min, dexmedetomidine 1...” NCT06423846

“One patch of SyB P-1501 contains 10.8 mg of fentanyl hydrochloride (fentanyl 9.7 mg) and produces an electric current to deliver the drug iontophoretically after the system is...” NCT03005899

“Intravenous moderate sedation (fentanyl 100 mcg and midazolam 2 mg) versus oral analgesia/anxiolysis (lorazepam 2 mg sublingual, hydrocodone/acetaminophen 5/500 mg, and...” NCT01011634

“In the Remifentanil group, patients will be administered in a total volume of 20 mL, 2 mcg/kg of fentanyl. As maintenance, they will be receiving 1 mL/10kg/h of a remifentanil solution” NCT05717361

“In addition to propofol as a hypnotic and rocuronium as a muscle relaxant, patients in the conventional opioid-based group will receive the following drugs: Remifentanil and FentanylNCT05485480

Fentanyl 2mcg/kg only at induction and infusion of propofol and remifentanil for maintenance, with doses adjusted according to bispectral index indication ( BIS maintained 40-60).” NCT04976842

“This study aimed to investigate the effect of the equivalent doses of fentanyl, oxycodone, and butorphanol on bowel function in patients undergoing laparoscopic hysterectomy.” PMID 35209847 Feb 2022

“General anesthesia will be induced with fentanyl 1,5 mcg/kg, propofol 2 mg/kg, rocuronium 0,6 mg/kg; after intubation anesthesia will be mantained with sevoflurane (MAC 1).” NCT04294537

“General anesthesia: induction of general anesthesia to facilitate endotracheal intubation: fentanyl (up to 2μg.kg.min-1), propofol (1-2 mg.kg-1), vecuronium (1-2 mg.kg-1).” NCT05444751

“general anesthetic by midazolam 0.02 mg kg-1 , propofol 2-3 mg kg-1 and lidocaine 0.5 mg kg-1 , fentanyl 2 μg kg-1 , atracurium 0.5 mg kg-1 , isoflurane in 50% oxygen/air.” NCT03569046

“Injection of 100 mcg of morphine, 15 mcg of fentanyl and 0.25 ml of normal salin (sterile) with 12 mg of bupivacaine in the intrathecal space to provide spinal anesthesia.” NCT05099055

“Standard thoracic epidural analgesia mixture (2 mg/ ml bupivacaine, 2 µg/ ml fentanyl and 2 µg/ ml adrenalin) with an infusion of 6-10 ml/hour until day 2 postoperatively.” NCT04025606

“Induction of anaesthesia: fentanyl 1 μg.Kg-1, propofol 1.5-2 mg.kg -1 titrated to loss of verbal response, atracurium 0.5 mg. Kg-1 to facilitate endotracheal intubation.” NCT04095754

“with fentanyl, (1mcg / kg), propofol (1-2 mg / kg), atracurium (0.5 mg / kg), intubation. Anesthesia maintained using Propofol (4-6) mg/kg/h, fentanyl (0.5-1) μg/kg/h.” NCT03437213

“Compare the opioid based anesthesia with Fentanyl and Remifentanyl to opioid free anesthesia with dexmedetomidine and lidocaine and their effect on postoperative pain.” NCT03417193

“Total IntraVenous Anesthesia - to achieve deep-sedation via chemical analgesic (propofol, dexmedetomidine, fentanyl, hydromorphone); continuous intravenous infusion.” NCT07672301

“Propofol 1,5mg/Kg, supplemented by fentanyl 2mcg/Kg and rocuronium 0,5mg/Kg and O2 100% will be for induction to anesthesia and facilitate endotracheal intubation. .” NCT04802122

“using dexmedetomidine, propofol and fentanyl as total intravenous anaesthestics (TIVA) in comparison with sevoflurane - fentanyl anesthesia in brain tumor resection.” NCT02575521

“both midazolam (0.05 mg/kg body weight; 1 mg if age \> 70 or ASA class III-IV) and fentanyl (50 µg; 25 µg if age \> 70 or ASA class III-IV) were given intravenously” NCT01321047

“In this group patient will receive intrathecal hyperbaric bupivacaine based on patients height and weight according to Harten chart with 10 μg of fentanyl (0.1 ml)” NCT04082676

“may use a combination of fentanyl, midazolam, dexmedetomidine infusion (with or without loading dose), and/or low-dose propofol by intermittent bolus or infusion” NCT03263117

“Droperidol 1.25 mg and fentanyl 0.025 mg (diluted with normal saline up to 5ml) is to be administrated intravenously 30 minutes before the end of the procedure.” NCT05068180

“Induction agents will be administered as quick boluses (Propofol 2,5mg/kg total body weight, max 350mg, Fentanyl 250mcg, Rocuronium 1,2mg/kg ideal body weight).” NCT03239236

“PACU analgesia for both groups will be the usual care regime of fentanyl or hydromorphone bolus as prescribed by the physician anesthesiologist doing the case.” NCT05693675

“i.e., a programmed intermittent bolus of 10 ml of 0.1% bupivacaine and 2 μg/ml fentanyl every hour until the completion of labor and suturing of the incision.” NCT06580327

“Post-procedure analgesia in both groups was provided via IV fentanyl 0.5-1 µg/kg, administered as needed for patients reporting an NRS score greater than 4.” NCT07303309

“Anesthetic agents, including propofol, fentanyl, rocuronium, and sevoflurane, were used as part of standard anesthetic management during the procedure.” NCT07370779

“The participants will receive intravenous midazolam, propofol or fentanyl with topical proparacaine and sub-tenon's mixture of lidocaine and marcaine.” NCT04346095

“Induction with 1% propofol (2-3 mg/kg), fentanyl (1-3 mg/kg), and Rocuronium 1-1.5 mg/kg. Before the injection of propofol, 5 mL 1% lidocaine (50 mg)” NCT04281017

“Standardized general anaesthesia with fentanyl 2 mcg/kg ABW at induction, propofol 1.5 mg/kg, rocuronium 0.6 mg/kg, sevoflurane 1 MAC for maintenance” NCT07299630

“General anesthesia induction will be performed with fentanyl 1-2 μg/kg, propofol 2-3 mg/kg, and rocuronium 0.6 mg/kg and maintained with sevoflurane.” NCT06584695

“Patients were given 1.5 mcg/Kg of fentanyl intravenously. two minutes after the fentanyl dose, a dose of 1.5 mg/kg of propofol slowly over 2 minutes.” NCT04284644

“Local anesthesia (e.g., 2% Lidocaine) and conscious sedation (e.g., Fentanyl and Midazolam) will be administered to the patient during the procedure” NCT06426992

“Patients in all groups will be attached to IV PCA containing 10 mcg/ml fentanyl, 10 mcg bolus without infusion dose, and 10 min lock time protocol.” NCT05566561

“Epidural anesthesia placed at L1-L2 Epidural infusion of ropivacaine 0.2% + 3-4 mcg/ml fentanyl + saline 0.9% (100 ML) 3-5ml/ hr during 120 hours” NCT02617199

“Anesthesia will be maintained by total intravenous anesthesia with propofol infusion (4 to 12 mcg/kg/min) and fentanyl infusion (1-2mcg /kg/hour)” NCT06613893

“Patients will be subjected to total intravenous anesthesia with propofol-fentanyl+i.v. lidocaine infusion for the first 48 h postoperatively” NCT02786329

“Group FENT, consisting of 29 patients, underwent a saddle block with hyperbaric bupivacaine (2.5 ml) combined with fentanyl (0.5 ml; 25 μg).” NCT06216197

“patients will receive fentanyl 2 μg/kg loading dose which will be prepared over 20 ml syringe and infused over 10 minutes prior to induction” NCT04941040

“Optional intrathecal opioid adjuncts, with fentanyl or sufentanil, may be used to enhance analgesia according to routine clinical practice.” NCT07334132

“Induction of anesthesia will be done by injecting fentanyl 2 μg/kg, propofol1.5-2.5 mg/kg and atracurium 0.5 mg/kg for muscle relaxation.” NCT05632159

“Patients will receive continuous epidural analgesia using bupivacaine 0.125% in conjunction with fentanyl 2 ug/ml at a rate of 8-15 ml/hr” NCT04541719

“intrathecal 50 mg (2.5 ml) of prilocaine 2% (Takipril, prilocaine hydrochloride 20 mg/mL, hyperbar, Sintetica) + 25 ug fentanyl (0.5 ml).” NCT06133881

“Group M will be given a 0.5% Bupivacain Dosage Regimen with weight and height adjustment+15 μg fentanyl +150 μg morphine intrathecally.” NCT05405049

“Epidural medication will be the same in both groups and will consist of bupivacaine 0,05% with fentanyl 2 µg/mL and adrenaline 2 µg/mL.” NCT05534945

“epidural anesthesia: patients get an continuous infusion of a solution with bupivacain 1 mg/ml, fentanyl 1 ug/ml and adrenalin 1 ug/ml” NCT02030717

“Boluses of fentanyl 1 µg/kg actual body weight (ABW), up to a maximum dose of 100 µg per bolus, can be given per clinical judgement.” NCT04679818

“Intravenous sedation in control group will be continued as initiated at the ICU e.g. propofol, fentanyl, midazolam, dexmedetomidine” NCT04355962

“patients will be premedicated with the undiluted IV formulation of fentanyl citrate (50 µg/mL), 10 µg/kg up to 400 µg per patient.” NCT04991298

“Intra-operatively, opioids will be titrated to heart rate and spontaneous respiration rate e.g. fentanyl, morphine, hydromorphone.” NCT03471442

“Standard sedation: fentanyl 2x0,5 microg/kg at beginning of procedure and propofol PCS: 20mg bolus than 10mg/bolus, lock-out = 0.” NCT00913861

“1- Standard dose group: receiving the typical dose of hyperbaric bupivacaine (12.5 mg hyperbaric bupivacaine + 25 mcg fentanyl).” NCT07140640

“administer anesthesia based on opioids such as fentanyl and/or morphine to guarantee analgesia during the surgical intervention.” NCT05887258

Fentanyl infusion (0.5 μg/kg/h) was started after induction and continued intraoperatively according to institutional protocol.” NCT07259057

“The unit's protocol includes drugs such as Morphine, Hydromorphone, Fentanyl, Clonidine, Ketamine, Midazolam and Acetaminophen.” NCT04538573

“Induction was carried out by fentanyl 3mcg/kg, propofol 2 mg/kg and rocuronium at the dose of 1mg/kg to facilitate intubation” NCT05417529

“Patient in this group will receive the intraoperative standard of care(intraoperative intravenous fentanyl and paracetamol)” NCT03762343

“Anaesthesia induction will be obtained with i.v. 2-3 mg/kg propofol, 0,6-0,8 mcg/kg fentanyl, and 0.9-1,2 mg/kg rocuronium.” NCT03157479

“Intravenous injection midazolam 0.05 mg/Kg,fentanyl 4μg/Kg,etomidate 0.2 mg/Kg,cisatracurium 0.15 mg/Kg in proper order.” NCT02289391

“Administer 7 μg/kg of fentanyl first,then given remimazolam 0.2 mg/kg (1-minute bolus), followed by 1 mg/kg/h infusion.” NCT07335536

“atracurium 0.5mg/kg to facilitate endotracheal intubation and fentanyl 1 mcg/kg ,Mechanical ventilation was adjusted” NCT04614259

“The ED95 of Ciprofol for Laryngeal Mask Airway Insertion With Fentanyl in Children: A Biased-Coin Dose-Finding Trial” NCT07697404

“Propofol 5-6 mg/kg and fentanyl 2 µg/kg for induction of anesthesia and propofol 250-300 µg/kg/min for maintenance” NCT03553082

“GA will be induced with midazolam 1-2 mg, fentanyl 2μ/kg and propofol titrated to achieve loss of consciousness.” NCT03013075

“using intraoperative opioids such as fentanyl or remifentanil, administered according to institutional protocols” NCT07310524

“Patients received inhalation induction using sevoflurane 8% and fentanyl 2 µg/kg was administered intravenously.” NCT05019560

“Intraoperative opioids (Fentanyl or Morphine) will be administered as deemed necessary by anesthesia care team.” NCT01500109

“Participants in the interventional group will receive an initial dose of 100 mcg IV fentanyl during induction.” NCT07614607

“general anesthesia induction with 1mcg/kg of IV Fentanyl, 2mg/kg of IV Propofol and 0.5 mg/kg of IV Atracurium” NCT06202664

“IV PCA (fentanyl 10mcg/kg + nefopam (Acupan®) 80mg + Ramosetron (Nasea®) ) apply 30min before end of surgery.” NCT03462836

“Patients will receive 150% of their oral morphine equivalent (OME) utilizing the drugs Dilaudid and Fentanyl.” NCT01447888

“Subarachnoid block will be performed using Bupivacaine hydrochloride (2.2 mL) in addition to fentanyl 25 mcg.” NCT03792906

“patients in group C will receive fentanyl 1 μg/kg, propofol 2.5 mg/kg, and rocuronium 0.3 mg/kg intravenously” NCT07680400

“All patients were induced with individual intravenous doses of midazolam, rocuronium, fentanyl and propofol.” NCT02399397

“The administered drugs, as outlined in the arms section, are midazolam, fentanyl, propofol, and sevoflurane.” NCT02058511

“Subarachnoid block will be performed using Bupivacaine hydrochloride (2.2 mL) in addition to fentanyl 25 mcg” NCT03712111

“Analgesia will be provided by fentanyl in induction and maintenance according to Ideal Body Weight (IBW)” NCT06343753

“10 mg of preservative-free isobaric bupivacaine with 12.5mcg of fentanyl injected to the epidural space” NCT03110003

“standard care which includes ketorolac, bupivacaine, fentanyl, ondansetron, dexamethasone, sevoflurane” NCT01868425

“Prior to emergence, 100-200 mcg of fentanyl will be titrated for additional analgesia after emergence.” NCT03908944

“General anesthesia with Lidocaine 1.5mg/kg, Fentanyl 2 mcg/kg, propofol 2 mg/kg, Rocuronium 0.6 mg/kg” NCT06892600

“with 1 microgram/kilogram (mcg/kg) of fentanyl and 1.2 mg/kg rocuronium once IV access is established” NCT03408340

“Total intravenous anesthesia (propofol plus fentanyl) in addition to remote ischemic preconditioning” NCT02877238

“After intravenous (IV) placement, 1-3mg/kg of propofol and 1mcg/kg of fentanyl will be administered.” NCT03467750

“Patients in both groups will receive intravenous patient-controlled analgesia (PCA) using fentanyl.” NCT01833728

“Propofol 2-3mg/kg IV, Fentanyl 1mcg/kg IV, neuromuscular block w/succinylcholine and/or rocuronium” NCT03448068

“Anesthesia was maintained with isoflurane at a concentration of 2-2.5%. fentanyl 50 ug increments” NCT02739958

“The doses used of Levobupivacaine Hydrochloride 0.5% will be 6 mg and the dose of fentanyl 10 μg.” NCT03843970

“Intraoperative: fentanyl 5-10 mcg/kg at induction with supplemental 1-2 mcg/kg boluses as needed.” NCT07658521

“The anesthesiologist will administer 4 mL of ropivacaine 0.5% plus fentanyl 15 mcg intrathecally” NCT05824338

“Tetracaine 2mg will be combined with Fentanyl 20 mcg and Epinephrine 50 mcg to treat labor pain.” NCT01005459

“The patients will receive a single injection of spinal anesthesia using prilocaine plus fentanylNCT06165679

“rescue intravenous analgesia using 50 mcg of fentanyl will be administered by anaesthesiologist” NCT04500249

“Spinal anesthesia performed with 12,5mg of bupivacaine with 25mcg fentanyl for cesarean section” NCT03231436

fentanyl 2 mcg/kg (bolus) and morphine given by PCA (patient-controlled analgesia) at 1 mg/dose” NCT05069311

“In the ED Rescue analgesic medication for all patients: Fentanyl 50mcg i.v. (max. 200mcg/hour)” NCT04685291

“A patient controlled device prepared with 10 mcg/ ml fentanyl will be attached to all patients” NCT04189640

“A patient-controlled device prepared with 10 mcg/ ml fentanyl will be attached to all patients” NCT06866054

“Participants will receive usual care with IV Fentanyl or hydromorphone per hospital protocols” NCT06110546

“intranasal fentanyl (INF) is effective for rapidly decreasing MSK-I related pain in children” NCT02985177

“50 mcg of fentanyl citrate was given as a 15-minute intravenous infusion in 150 cc isotonic.” NCT05500677

“IV-PCA (fentanyl 10 mcg/ml) Dose bolus-lock out time - basal = 1.5 ml - 15 min - 1.5 ml/hr” NCT01269099

“to characterize the pharmacokinetics profile of ACTIQ (fentanyl citrate) in these children” NCT00236041

“All patients will receive a standarised dose of paracetamol 15mg/kg and fentanyl 2mcg/kg.” NCT03167047

“We thus determine appropriate dose of fentanyl (bolus dose and background infusion rate)” NCT01863355

“iv-PCA setting was fentanyl 20 mcg/ml, bolus/lock out time/basal, 0.5 ml/15 min/0.5 ml.” NCT02491385

“Traditional general anesthetic technique utilizing sufentanil, fentanyl or remifentanil” NCT02752477

“Anesthesia is induced with 1 µg/kg fentanyl, 1.5-2 mg/kg propofol and 1-2 mg midazolam.” NCT02534012

“in combination with Fentanyl (25µg) in day-case lower abdominal and urologic surgeries” NCT05726968

“8 mg hyperbaric bupivacaine with added 25 µg fentanyl to form a total volume of 2.1 ml” NCT03356899

“Patients will receive o.5 ug/kg/hr fentanyl infusion all through the whole operation.” NCT06984276

“patient control epidural analgeisa using 0.2% levobupivacaine with 2ug/ml fentanylNCT01158586

Fentanyl was administered at a dose of 3 mcg/kg at 5 minutes of this application.” NCT06958913

“Patients will be anesthetized using Fentanyl (2 mcg/kg) and Propofol (1-2 mg/kg).” NCT04473846

“Patients received 0.5% bupivacaine hyperbaric (2.5 ml) + fentanyl 25 µg (0.5 ml).” NCT07664618

“They will receive 20 mg of 0.5% hyperbaric bupivacaine plus 25 microgram fentanylNCT06550180

“Hydromorphone or fentanyl will be used in patients who do not tolerate morphine.” NCT01932554

“1 microgram/kg Fentanyl, and 2 minutes later receive 1 mg/kg Propofol (Diprivan)” NCT02079090

“During general anesthesia, fentanyl is administered according to NOL monitoring.” NCT06070701

“Spinal anesthesia will be induced with isobaric 2% lidocaine and 15 μg fentanyl.” NCT02574832

“the EDA group had an epidural infusion of bupivacaine, adrenalin and fentanyl.” PMID 30837253 Mar 2019

“Patients in both groups received fentanyl 2 ug\\kg and atracurium 0.5 mg\\kg.” NCT04365686

“All patients will receive a spinal anesthetic using Fentanyl and Bupivacaine” NCT02197273

“The bolus will consist of 2.5mL of 0.25% Bupivacaine plus fentanyl 8mcg/ml.” NCT03735771

“3.0 ml of heavy levo-bupivacaine with10 µg fentanyl (0.5 ml) to make 3.5 ml” NCT06970574

“Induction by intravenous fentanyl (1.5 µg kg-1) and propofol (2.5 mg kg-1)” NCT02355678

“5 mg hyperbaric bupivacaine 0.5% and 25 mcg fentanyl for spinal anesthesia” NCT03834454

“propofol 2mg/kg , atracurium0.5ml/kg ,fentanyl 100 microgram in induction” NCT03422354

“Sedation will be administered using low-dose midazolam and/ or fentanyl.” NCT04887285

“initial bolus dose of fentanyl (fentanyl 50 mcg/ml, hameln; Netherlands)” NCT06464263

“Midazolam, Propofol, Fentanyl, Cisatracurium or alternatively Rocuronium” NCT05172739

Fentanyl will be given, if needed, in doses of 0.25-0.5 mg intravenously” NCT07637279

“Prilocaine 40mg (2ml) + fentanyl 25mcg in unilateral spinal anesthesia” NCT07262398

Fentanyl (Actiq®, Duragesic®, Fentora®, Lazanda®, Subsys®, and others)” NCT06240390

“Both groups will receive the same medications (propofol and fentanyl).” NCT07569016

“20 mcg of "Fentanyl," "Martindale pharma Fentanyl®," 50mcg/ml (0.4ml)” NCT06769737

“with intra-operative fast acting opioid analgesics, Fentanyl 2 mic/kg” NCT04238377

“patients will receive fentanyl (3-6 mcg/kg) at anesthesia induction.” NCT00413582

“using 10mg of 0.5% hyperbaric Bupivicaine and Fentanyl 20 micrograms” NCT02784340

Fentanyl, an opioid, is strongly related to the development of PONV” PMID 38335521 Feb 2024

“Standard epidural placement. Ropivacaine 0.1% and Fentanyl 2mcg/mL.” NCT03074695

“ * Fentanyl * Benzodiazepine and / or anti-psychotic for agitation” NCT02009306

“1 ml 0.5% isobaric bupivacaine (5 mg) + 15 mcg fentanyl intrathecal” NCT03993314

“Drug: High dose propofol, fentanyl and sevoflurane Deep Anesthesia” NCT05380778

“intra venous Narcotic drugs (fentanyl) in the dose of (1-2mcg/kg)” NCT03866733

“25, 35 mcg of Fentanyl (Fentanyl, Janssen Cilag, amp. 50 mcg/ml)” NCT02385539

“This group will receive fentanyl in the induction of anesthesia.” NCT03212456

“Propofol 2-3mg/kg, Fentanyl 1-2mcg/kg and Cisatracurium 0.2mg/kg” NCT04894864

Fentanyl 10 microg/ml at continuous flow of 10 to 20 microg/hour” NCT01607996

Fentanyl is administered at induction - standard dose 5 mcg/kg.” NCT04338984

“Group 2: PCEA with fentanyl 1 mcg/mL plus bupivacaine 0.8 mg/mL” NCT01074190

“propofol 1 mg/kg and fentanyl 1µg/kg will be administered IV” NCT06656455

“Initially, fentanyl was administered at a dose of 2-3 mcg/kg” NCT06816173

“Conventional sedation receiving analgosedation with fentanylNCT05559970

“0.1% Bupivacaine and 2microgram\\ml Fentanyl every one hour” NCT06494280

“intravenous administration of fentanyl 2µg/kg and propofol” NCT03600454

“Spinal anesthesia with bupivacaine 12.5 mg+fentanyl 15 ug” NCT03639389

Fentanyl 1 to 2 mcg/kg followed by IV lidocaine infusion” NCT07116564

Fentanyl * IV bolus of 1 µg/kg for sedation induction” NCT01840371

“50 micrograms of fentanyl given before the procedure” NCT01786434

“followed by an opioid such as fentanyl (1-2 mcg/kg)” NCT05509192

fentanyl 100 μg will be administered intravenously.” NCT07588802

“Morphine, oxycodone, metadone, fentanyl, tramadol” NCT03365817

“DepoDur with on demand boluses of IV fentanyl PCA” NCT00728832

fentanyl was administered at a dose of 2 mcg/kg” NCT06779968

“etomidate, fentanyl (1-2 mcg/kg) and rocuronium” NCT01566838

“Group 1: Levobupivacaine 8 mg + 20 mcg FentanylNCT03956303

“intrathecal bupivacaine 0.5% 15mg and fentanylNCT05602038

fentanyl 1 mcg/kg followed by 1 -2 mcg/kg/h” NCT05962671

fentanyl 50-100 mcg IV prior to intubation” NCT07211399

“0.0625% Bupivacaine plus fentanyl 2mcg/ml” NCT02887222

“Only received fentanyl IV during surgery.” NCT03879980

“Epidural fentanyl 200 microgram bolus” NCT00848419

“IV sedation with fentanyl and versed” NCT03187002

“propofol 2mg /kg ,fentanyl 2 mic/ kg” NCT05825430

“Bupivacaine 0.1%, fentanyl 1 mic/kg” NCT00801047

“Opioid based group receive fentanylNCT07360327

fentanyl 1 mcg/kg before induction” NCT01584570

“2 mcg/kg fentanyl in 10 ml volume” NCT05752799

Fentanyl rescue dose (1mcg/kg)” NCT07568938

“Transdermal Opioid (Fentanyl)” NCT03472469

Fentanyl 2-4 mcg/kg IV bolus” NCT04197570

“intravenous fentanyl boluses” NCT01571791

“IV Fentanyl and midazolam” NCT06899724

fentanyl (opioid agonist)” NCT04689217

“2. Recommended FentanylNCT01315158

“Transdermal fentanylNCT00916890

“-Fentanyl: 10 mic\ml” NCT02121951

Fentanyl: 1mcg/kg iv” NCT07558226

Fentanyl (50mcg IV)” NCT04081545

Fentanyl 1-2ug/kg” NCT01474252

“IV PCA(fentanyl)” NCT05053308

Fentanyl 10ug” NCT01511627

FentanylNCT02886286

FentanylNCT06930183

fentanylNCT03029676

NCT05769309

NCT02958566

NCT00871442

NCT03682211

NCT01497288

NCT02123589

NCT00741351

NCT06185127

NCT03649334

NCT00271414

NCT00713726

NCT00709254

NCT04199013

NCT01429051

NCT06435949

NCT03901716

NCT04004117

NCT01362998

NCT04095013

NCT02587273

NCT00387010

NCT02691572

NCT00293020

NCT06962306

NCT02388321

NCT00696137

NCT02501863

NCT03776838

NCT00685295

NCT02252458

NCT03507634

NCT03435692

NCT01327677

NCT01749579

NCT00596050

NCT02486016

NCT03491072

NCT00345735

NCT01896960

NCT03435003

NCT00822614

NCT07057739

NCT00271453

NCT04945694

NCT01913054

NCT02733705

NCT04762147

NCT00333632

NCT00779467

NCT00264485

NCT01795898

NCT06186895

NCT00882960

NCT01748630

NCT04196946

NCT05150795

NCT00465231

NCT03324490

NCT03434678

NCT07326332

NCT02713191

NCT03619785

NCT07182097

NCT05905367

NCT07241351

NCT07262242

NCT02466022

NCT01522729

NCT01750060

NCT01828840

NCT04564326

NCT03778671

NCT02732132

NCT04673812

NCT02277782

NCT03623256

NCT02789969

NCT03778723

NCT03344042

NCT04561375

NCT02426697

NCT00788372

NCT07610408

NCT02462915

NCT07610265

NCT00403663

NCT03343002

NCT04026022

NCT07078201

NCT06951230

NCT00271466

NCT01582607

NCT07076368

NCT03323684

NCT05975294

NCT02359175

NCT00666393

NCT02159807

NCT01563835

NCT01514695

NCT05148637

NCT04888858

NCT01427985

NCT00794209

NCT00803725

NCT00956254

NCT05641909

NCT04128540

NCT05706090

NCT03009877

NCT03077503

NCT02537860

NCT02880540

NCT04824274

NCT00538850

NCT05481970

NCT02623959

NCT02531165

NCT00241332

NCT03010540

NCT00538863

NCT00405444

NCT06662318

NCT03461718

NCT02387060

NCT06636578

NCT02734940

NCT01497509

NCT03252496

NCT00478101

NCT02584452

NCT01348984

NCT01975753

NCT07650552

NCT06917898

NCT03438240

NCT00151346

NCT01724983

NCT02122055

NCT02625181

NCT03143933

NCT04823390

NCT05445856

NCT06181188

NCT02267681

NCT07258628

NCT05510986

NCT00779038

NCT01816243

NCT01593397

NCT02616523

NCT05232084

NCT02222636

NCT06210061

NCT05332028

NCT07425444

NCT02278601

NCT02480114

NCT05639712

NCT02135224

NCT02528513

NCT06685705

NCT04285255

NCT00802646

NCT03013036

NCT04597320

NCT06823349

NCT02460055

NCT00996177

NCT00708318

NCT02150161

NCT00463047

NCT07141589

NCT00974220

NCT04871425

NCT02467023

NCT06318546

NCT03747094

NCT01651962

NCT02459964

NCT07332130

NCT00652028

NCT02794896

NCT07214714

NCT01998685

NCT04727515

NCT02209610

NCT04285528

NCT00641667

NCT06868589

NCT01794533

NCT06502262

NCT01960543

NCT02531529

NCT06367660

NCT00181246

NCT02467595

NCT02582372

NCT05550597

NCT00462644

NCT00648414

NCT00468052

NCT04854252

NCT06799442

NCT03922815

NCT02125201

NCT05850468

NCT01144312

NCT04011098

NCT06630364

NCT07120763

NCT02224443

NCT06763705

NCT00684632

NCT01842893

NCT04011150

NCT06382831

NCT03000413

NCT01809106

NCT02004899

NCT00512395

NCT02689024

NCT02150759

NCT05861791

NCT00115102

NCT05609877

NCT00667043

NCT03120780

NCT01648595

NCT05051007

NCT03265470

NCT05579509

NCT03959852

NCT03255824

NCT02039453

NCT03847792

NCT03015857

NCT03405090

NCT02289586

NCT04221568

NCT01549002

NCT02696915

NCT04026074

NCT06051227

NCT06539013

NCT04260659

NCT05244226

NCT02619032

NCT05386121

NCT01277861

NCT00126789

NCT03120442

NCT03195309

NCT00496392

NCT02476799

NCT00004424

NCT00723164

NCT05241054

NCT05051189

NCT01794247

NCT05502211

NCT04602845

NCT06034873

NCT01858090

NCT04202887

NCT00266539

NCT02997800

NCT02658721

NCT03120234

NCT01780233

NCT05998551

NCT03251170

NCT04136548

NCT04089592

NCT01368809

NCT06052111

NCT00126763

NCT03444636

NCT01602640

NCT02225210

NCT00857753

NCT06689124

NCT06590870

NCT02470390

NCT03789318

NCT06479655

NCT02753725

NCT01881997

NCT02531971

NCT03897452

NCT00795314

NCT07533643

NCT04062123

NCT01308320

NCT02798835

NCT00714558

NCT03596060

NCT02037802

NCT00724035

NCT05619887

NCT01169025

NCT03018756

NCT02951806

NCT06394375

NCT03834363

NCT01832402

NCT05314569

NCT01547416

NCT05543109

NCT07034950

NCT02037633

NCT06537323

NCT02012244

NCT03424356

NCT03019562

NCT04138472

NCT01062906

NCT02119806

NCT07092046

NCT03763305

NCT04659642

NCT02036697

NCT03792191

NCT05980546

NCT03383588

NCT06720285

NCT05145543

NCT07657897

NCT07636070

NCT04223219

NCT01244126

NCT03938831

NCT03938857

NCT06898697

NCT07224620

NCT03080324

NCT04188418

NCT03080350

NCT02494180

NCT05873465

NCT05654064

NCT02226328

NCT01980498

NCT02136641

NCT02698969

NCT01425658

NCT04403724

NCT02454751

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NCT01604187

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NCT03595397

NCT07035223

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NCT04397406

NCT06557473

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NCT04518618

NCT07711522

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NCT04292990

NCT01843296

NCT07156968

NCT03214510

NCT01934088

NCT04955236

NCT03476369

NCT07117565

NCT03548493

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NCT01205204

NCT04871061

NCT06867068

NCT02597478

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NCT02651311

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NCT00738192

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NCT03667352

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NCT02430090

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NCT06793358

NCT07091123

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NCT01729897

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NCT04648540

NCT04410588

NCT00237341

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NCT03117595

NCT03983889

NCT01608334

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NCT05218733

NCT03030911

NCT06820203

NCT01627873

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NCT04713189

NCT02014714

NCT02065947

NCT02858622

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NCT02577809

NCT00214370

NCT07040163

NCT05057689

NCT01544959

NCT03052673

NCT02949271

NCT02078583

NCT05014711

NCT02450084

NCT06907277

NCT05539911

NCT02084355

NCT06412861

NCT00459277

NCT06126991

NCT00362583

NCT07019805

NCT02604459

NCT07276867

NCT07166666

NCT01205997

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NCT02313337

NCT03365115

NCT01488045

NCT05659823

NCT06395727

NCT07435337

NCT00402350

NCT02324933

NCT05367336

NCT04645823

NCT02577432

NCT03751423

NCT02116842

NCT06464393

NCT00654329

NCT00270322

NCT04204967

NCT06060626

NCT02031016

NCT02684942

NCT04078659

NCT00527332

NCT02641340

NCT00419601

NCT04414800

NCT01851720

NCT06464146

NCT03063866

NCT02138396

NCT02510287

NCT06576830

NCT03523000

NCT07148882

NCT05602519

NCT07165262

NCT01774929

NCT07640516

NCT01258296

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NCT04226885

NCT01937767

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NCT02138409

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NCT03063359

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NCT00337792

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NCT00286143

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NCT01234272

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NCT07684365

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NCT03088306

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NCT04418674

NCT01159262

NCT00650182

NCT02326727

NCT00214942

NCT03204045

NCT07459166

NCT03803267

NCT00228605

NCT00279344

NCT06203405

NCT03803449

NCT05489796

NCT00654511

NCT02115360

NCT00702416

NCT00978978

NCT04544163

NCT04048200

NCT07149545

NCT01060137

NCT00542542

NCT01892332

NCT07190625

NCT02197988

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NCT06862154

NCT05688449

NCT02314351

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NCT00214955

NCT01508455

NCT00108446

NCT00807209

NCT02349152

NCT07350668

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NCT01903421

NCT04899388

NCT01114971

NCT03199157

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NCT04932083

NCT00390871

NCT01726530

NCT00706277

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NCT02669186

NCT06785987

NCT02445599

NCT02576353

NCT04908345

NCT05487196

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NCT05379179

NCT02861716

NCT02327923

NCT00236366

NCT03887260

NCT00848393

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NCT00842829

NCT05957302

NCT03171610

NCT06834841

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NCT02444897

NCT02474654

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NCT02988219

NCT02174913

NCT02961842

NCT06609993

NCT05003102

NCT01804673

NCT03806374

NCT02635282

NCT03858621

NCT02987985

NCT06834854

NCT06561672

NCT07285759

NCT06531759

NCT04937946

NCT02203175

NCT05089526

NCT02203019

NCT00926705

NCT03973957

NCT07062601

NCT04177862

NCT03824665

NCT06033729

NCT05165992

NCT03807011

NCT04528173

NCT02752308

NCT07445672

NCT00278824

NCT04177342

NCT00576017

NCT00446420

NCT01838707

NCT01333059

NCT00236093

NCT03824314

NCT03128346

NCT03528512

NCT01846221

NCT04621110

NCT00771199

NCT02970097

NCT04442906

NCT07112430

NCT01403363

NCT05201560

NCT04745260

NCT05024799

NCT01008553

NCT01210066

NCT07238101

NCT02717780

NCT04872881

NCT03293927

NCT01515566

NCT02489019

NCT01081535

NCT02862912

NCT04160598

NCT03400267

NCT02653742

NCT03529201

NCT03112564

NCT03809182

NCT03480308

NCT00158873

NCT01007773

NCT01845441

NCT00269763

NCT06507397

NCT06650371

NCT03726268

NCT05429567

NCT02421341

NCT04230681

NCT07556133

NCT06722963

NCT01703351

NCT01506622

NCT03755609

NCT06498037

NCT01666379

NCT02442128

NCT02758405

NCT03885596

NCT07556523

NCT04933058

NCT01373021

NCT03260283

NCT02869321

NCT02514252

NCT01558713

NCT01950000

NCT03307174

NCT02128451

NCT06784180

NCT00187135

NCT02202239

NCT03809949

NCT07557576

NCT00236327

NCT02521415

NCT02638506

NCT01621230

NCT01303731

NCT05500599

NCT03105115

NCT00269737

NCT06953453

NCT01839552

NCT04983615

NCT00216684

NCT00813488

NCT00454259

NCT03051503

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NCT07443254

NCT06330168

NCT04318158

NCT02056288

NCT03606902

NCT07161297

NCT00772187

NCT04635852

NCT02634255

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NCT02983344

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NCT03105518

NCT03296488

NCT01195103

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NCT02915978

NCT02270437

NCT03401593

NCT04026451

NCT07267377

NCT05137184

NCT00236145

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NCT01972269

NCT03305055

NCT06326944

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NCT01008618

NCT03968146

NCT02533908

NCT00105287

NCT01127100

NCT01304342

NCT07560501

NCT01126957

NCT00647127

NCT03057041

NCT03167905

NCT01158820

NCT00434382

NCT02331576

NCT00524160

NCT01620047

NCT04444635

NCT01079312

NCT01147146

NCT07368738

NCT00959400

NCT02408146

NCT05596227

NCT02608320

NCT02518789

NCT07105618

NCT01205360

NCT03355716

NCT03813303

NCT03718507

NCT07443085

NCT00815048

NCT00105937

NCT02375191

NCT02419547

NCT01440114

NCT01248611

NCT00815022

NCT06392321

NCT03450161

NCT01768377

NCT06752629

NCT02172014

NCT00580489

NCT00691795

NCT05596552

NCT05531422

NCT00864565

NCT03854812

NCT04315935

NCT00523887

Known as Abstral “Ten minutes before the procedure fentanyl sublingual tablet (Abstral ® 100 µg, ProStrakan) will be given to the patient.” NCT01604187
1

AbstralNCT03080324

Known as Actiq Actiq® 400 µg is a solid formulation of fentanyl citrate on a plastic stick that dissolves slowly in the mouth for absorption across the buccal mucosa.” NCT01780233
3

“Fentanyl (Actiq®, Duragesic®, Fentora®, Lazanda®, Subsys®, and others)” NCT06240390

ACTIQ (Oral Transmucosal Fentanyl Citrate [OTFC])” NCT00236093

ACTIQ (Oral transmucosal fentanyl citrate)” NCT00236145

Known as AD 923 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00635063
Known as AeroLEF “Study Evaluating Inhaled AeroLEF (Liposome-Encapsulated Fentanyl)in Normal Healthy Subjects” NCT00708318
1

“one dose (5mL) of inhaled AeroLEF (500 mcg/mL as fentanyl base)” NCT00794209

Known as BEMA Fentanyl “Study of the Safety of BEMA™ Fentanyl Use for Breakthrough Pain in Cancer Subjects on Chronic Opioid Therapy” NCT00293020
Known as Breakyl ChEMBL registry synonym — accepted as the source's own label CHEMBL596
Known as Colgate total toothpaste ClinicalTrials.gov intervention name — accepted as the source's own label NCT05868200
1

NCT02080273

Known as Control Group ClinicalTrials.gov intervention name — accepted as the source's own label NCT02592278
1

NCT07276802

Known as Duragesic “This is an Open-label, Non-Randomized, 3-way Crossover Bioequivalence Study to compare fentanyl release after heating of a brand name (Duragesic) and generic (Apotex and Mylan)...” NCT02486016
8

“For patients who were using transdermal fentanyl (ie,Duragesic®), the initial dose of ZR-02-01 was the same as their current Duragesic dose.” NCT00126763

“In addition, fentanyl is currently marketed for transdermal use (Duragesic fentanyl transdermal patch) for the management of chronic pain.” NCT00714558

“Study of the Effect of Clinical Procedures on Drug Delivery of Mylan Fentanyl Transdermal System 25 µg/hr and Duragesic® 25 µg/hr” NCT00648414

“Fentanyl (Actiq®, Duragesic®, Fentora®, Lazanda®, Subsys®, and others)” NCT06240390

Duragesic® (fentanyl) Transdermal Therapeutic System (TTS)” NCT00271414

“then wore a Duragesic® fentanyl TDDS (25 µg/h) for 72 h” NCT02531971

Duragesic® (Fentanyl Transdermal System)” NCT00237341

Duragesic (fentanyl transdermal system)” NCT00650182

Known as Duragesic fentanyl skin patch “Duragesic® fentanyl skin patch” NCT02531971
Known as Duragesic-100 ChEMBL registry synonym — accepted as the source's own label CHEMBL596
Known as Duragesic-12 ChEMBL registry synonym — accepted as the source's own label CHEMBL596
Known as Duragesic-25 ChEMBL registry synonym — accepted as the source's own label CHEMBL596
Known as Duragesic-37 ChEMBL registry synonym — accepted as the source's own label CHEMBL596
Known as Duragesic-50 ChEMBL registry synonym — accepted as the source's own label CHEMBL596
Known as Duragesic-75 ChEMBL registry synonym — accepted as the source's own label CHEMBL596
Known as Duragesic Duragesic® (fentanyl) Therapeutic Transdermal System (TTS)” NCT00271466
Known as Durogesic “Open-Label Study To Assess The Effect On Pain Control Of Durogesic (Fentanyl Transdermic Therapeutic System) Treatment In Subjects With Rheumatoid Arthritis Or Osteoarthritis...” NCT00524160
2

“One DUROGESIC transdermal patch containing 8.4 mg of fentanyl applied on the skin for 72 hours.” NCT01717157

Durogesic® (fentanyl transdermal drug delivery system)” NCT00271453

Known as Durogesic d-trans ChEMBL registry synonym — accepted as the source's own label CHEMBL596
Known as Effentora ChEMBL registry synonym — accepted as the source's own label CHEMBL596
Known as EN3267 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00263575
Known as engineered HB vaccine ClinicalTrials.gov intervention name — accepted as the source's own label NCT00939068
Known as FBT “Previous single-dose studies found that prophylactic administration of fentanyl buccal tablet (FBT) improved exertional dyspnoea.” PMID 41115797 Mar 2026
2

“Fentanyl buccal tablets (FBT) placed in the buccal cavity above a rear molar until disintegrated, approximately 14-25 minutes.” NCT00387010

“A Preliminary Study of Prophylactic Fentanyl Buccal Tablets (FBT) for Exercise Induced Breakthrough Dyspnea” NCT01856114

Known as FCIV “Fentanyl Citrate IV (FCIV)” NCT02576353