drugset / Trial / NCT07190625
Intranasal Versus Intravenous Fentanyl For Procedural Analgesia in Preterm Neonates
RandomizedParallel-groupOpen-labelSupportive care
Summary
Pain in neonatal life has profound long-term developmental impacts, so pain control is crucial. The intranasal (IN) route is a minimally invasive method for rapidly delivering fentanyl to provide short-term analgesia and sedation in adults and pediatrics, but few data exist about its use in neonates. Meanwhile, intravenous fentanyl is widely used in sedation and pain management. Using intranasal fentanyl as an analgesic in preterm neonates may provide a rapid, effective, noninvasive route for administration.
Timeline
- Start
- 2023-12-24
- Primary completion
- 2026-03-01
- Completion
- 2026-06-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Fentanyl | Other / unclassified | 1 ug/kg | Intravenous |
| Comparator | Fentanyl | Other / unclassified | 1.5 ug/kg | Intravenous |
Indications
No indication recorded.