Use of Remimazolam and Fentanyl for Procedural Sedation in Patients Undergoing Dental Extraction
Summary
The goal of this clinical trial is to learn if a combination of the two established sedation drugs remimazolam and fentanyl, can put the subject to sleep during a scheduled extraction procedure. The combined use of these drugs has been used in other studies involving IV sedation when the procedure is scheduled for 30 minutes or less. However, the combined use of the IV sedation drugs has not been used in a dental extraction procedure before. The main questions it aims to answer are: 1. Can the combined drugs effectively put the patient to sleep during the procedure 2. How quickly will they come out of the sedation after the procedure Participants will: 1. Receive the combined drugs during a scheduled extraction procedure anticipated to take less than 30 minutes 2. Answer survey questions related to their study experience after the extraction visit (in person) and again about 24 hours after the visit (by telephone).
Timeline
- Start
- 2025-07-31
- Primary completion
- 2026-02-27
- Completion
- 2026-02-27
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Fentanyl | Other / unclassified | 25 ug | Intravenous |
| Subject | Fentanyl | Other / unclassified | 50 ug | Intravenous |
| Subject | Remimazolam | Small molecule | 5 mg | Intravenous |
Indications
No indication recorded.