drugset / Trial / NCT05367336
Platelet Reactivity With Fentanyl, Morphine, or no Narcotic
Non-randomizedParallel-groupOpen-labelTreatment
Summary
The goal is to determine whether fentanyl and morphine have similar effects in reducing aspirin's effect upon platelets in emergency department patients with chest discomfort. Morphine has been shown to worsen outcomes in heart attack patients due to reduction of oral anti-platelet agent effectiveness and so many providers have switches to using fentanyl. However, it is largely unknown whether fentanyl has similar effects.
Timeline
- Start
- 2022-08-31
- Primary completion
- 2025-02-18
- Completion
- 2025-02-18
Outcome
Outcome not reported
Stopped (Enrollment): “The study was halted prematurely due to difficulties in recruiting a sufficient number of participants. Despite efforts to enroll eligible individuals, the recruitment goals were not met, making it infeasible to continue the study as planned.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Fentanyl | Other / unclassified | — | — |
| Subject | Morphine | Other / unclassified | — | — |