Drugs / Morphine
last change 3 days ago re-read 2 minutes ago

Morphine

Other / unclassified targets OPRM1

Developed for
chronic pain syndrome · neuropathy, painful · osteoarthritis, knee · substance-related disorder · acute myocardial infarction · cancer · chronic obstructive pulmonary disease · opiate dependence
+70 more · osteoarthritis · heroin dependence · pregnancy disorder · scoliosis · appendicitis · idiopathic pulmonary fibrosis · lumbar disk disease · metastatic malignant neoplasm · neonatal abstinence syndrome · obstructive sleep apnea syndrome · opioid abuse · pain agnosia · sickle cell disease · ST-elevation myocardial infarction · urinary system disorder · urolithiasis · acute respiratory failure · ankle defects short stature · bone pain, periodic · breast cancer · chronic ulcer of skin · colorectal cancer · complex regional pain syndrome type 1 · decubitus ulcer · epidermolysis bullosa · head and neck cancer · headache disorder · hemorrhoid · interstitial lung disease · intervertebral disk degenerative disorder · ischemic disease · mucositis · musculoskeletal system disorder · nephrolithiasis · postherpetic neuralgia · radiculopathy · rheumatic disorder · rotator cuff syndrome · sciatica · stomatitis · subacute delirium · substance withdrawal syndrome · ulcer disease · urinary tract obstruction · acute coronary syndrome · adolescent idiopathic scoliosis · akinetic mutism · bone disorder · brain hypoxia - ischemia · brain injury · brain neoplasm · cardiac arrest · delirium · diabetic polyneuropathy · disease of the tendon · dwarfism thin bones multiple fractures · heart valve disorder · ileus · neoplasm · nephroma · neurological pain disorder · obstetric disorder · osteoarthritis, hip · parotitis · postoperative ventricular dysfunction · pulmonary arterial hypertension · pulmonary edema · sleep apnea syndrome · spinal cord injury · subjective cognitive decline
Investigated by
National Institute on Drug Abuse (NIDA) · Actavis Inc. · Pfizer · Seoul National University Hospital · EKR Therapeutics, Inc · Javelin Pharmaceuticals
+268 more · Johns Hopkins University · Northwestern University · QRxPharma Inc. · The Hospital for Sick Children · Alza Corporation · Assistance Publique - Hôpitaux de Paris · B.P. Koirala Institute of Health Sciences · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Mahidol University · National Institutes of Health (NIH) · National Taiwan University Hospital · Pacira Pharmaceuticals, Inc · Post Graduate Institute of Medical Education and Research, Chandigarh · Rambam Health Care Campus · Roxane Laboratories · Tanta University · Washington University School of Medicine · Aalborg University · Albert Einstein College of Medicine · Assiut University · AstraZeneca · Ataturk University · Cairo University · Canadian Institutes of Health Research (CIHR) · Central Hospital, Nancy, France · Charles University, Czech Republic · Children's Hospital of Fudan University · Cork University Hospital · Egalet Ltd · Erasmus Medical Center · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · Federal University of São Paulo · Flinders University · French National Institute of Health and Medical Research · Hospital Central do Funchal · Indiana University · Isfahan University of Medical Sciences · Kafrelsheikh University · M.D. Anderson Cancer Center · Mayo Clinic · Mbarara University of Science and Technology · Meri Mirceta · Mount Sinai Hospital, Canada · National Cancer Institute (NCI) · National Institute of Nursing Research (NINR) · Nova Scotia Health Authority · Pamukkale University · PriCara, Unit of Ortho-McNeil, Inc. · Sohag University · Stanford University · Tehran University of Medical Sciences · Tel-Aviv Sourasky Medical Center · The Methodist Hospital Research Institute · The Second Hospital of Anhui Medical University · University Hospital, Rouen · University of Iowa · University of Louisville · University of Monastir · University of North Carolina, Chapel Hill · University of Rochester · University of Texas Southwestern Medical Center · University of Utah · AUSL Romagna Rimini · Aarhus University Hospital · Ain Shams University · Akdeniz University · Alaxia SAS · Alberta Health services · Alzahraa Ahmed Abbas · Anne Juul Wikkelsø · Anqing Municipal Hospital · Asker & Baerum Hospital · Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil · Astellas Pharma Global Development, Inc. · all 274 on the full record

Regulatory milestones approvals, filings & regulatory actions · 5 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Label expansions (3) US (FDA) MORPHINE SULFATE 2010-01-25 – 2021-06-02 fda.gov
Label expansion US (FDA) ARYMO ER 2018-10-12 fda.gov
Approved US (FDA) DURAMORPH PF 1984-09-18 fda.gov

Trials 310 · started per year

today
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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 04 trials
Phase 0 NCT05019638 Mar 2021 → May 2028 expected University of Utah Active not recruiting No outcome recorded
Phase 0 NCT03926559 Apr 2019 → May 2021 Augusta University Unknown No outcome recorded
Phase 0 NCT05037812 Mar 2019 → Mar 2028 expected University of Utah Active not recruiting No outcome recorded
Phase 0 NCT02825056 Jul 2016 → Jun 2017 vascular disorder Post Graduate Institute of Medical Education and Research, Chandigarh Unknown No outcome recorded
Phase 119 trials
Phase 1 NCT05587998 Aug 2022 → May 2023 substance-related disorder AstraZeneca Completed No outcome recorded
Phase 1 NCT04448561 Jun → Sep 2020 substance-related disorder Astellas Pharma Global Development, Inc. Completed No outcome recorded
Phase 1 NCT03801629 Sep 2019 → Mar 2021 Yale University Completed No outcome recorded
Phase 1 NCT03425084 Jun 2018 → Feb 2020 University of Southern Denmark Completed No outcome recorded
Phase 1 NCT02824276 Jan 2017 → Dec 2022 Brigham and Women's Hospital Completed No outcome recorded
Phase 1 NCT02156596 Feb 2013 → Dec 2017 urinary tract obstruction University of Monastir Completed No outcome recorded
Phase 1 NCT01766960 Nov 2012 → Mar 2014 fatty liver disease University of North Carolina, Chapel Hill Completed No outcome recorded
Phase 1 NCT01476124 Aug → Oct 2011 restless legs syndrome XenoPort, Inc. Completed No outcome recorded
Phase 1 NCT00923000 Dec 2008 → Dec 2009 Tri-Service General Hospital (TSGH) Unknown No outcome recorded
Phase 1 NCT00802308 Dec 2008 → Feb 2009 Egalet Ltd Completed No outcome recorded
Phase 1/212 trials
Phase 1/2 NCT06875791 Dec 2025 → Dec 2026 expected head and neck squamous cell carcinoma, mucositis Fundacion Clinica Valle del Lili Not yet recruiting No outcome recorded
Phase 1/2 NCT06065956 Aug 2022 → Jun 2023 Pakistan Navy Station Shifa Hospital Completed No outcome recorded
Phase 1/2 NCT04427826 Dec 2020 → Jun 2027 expected chronic obstructive pulmonary disease University Hospital, Grenoble Recruiting No outcome recorded
Phase 1/2 NCT04138615 Nov 2019 → Jan 2022 University of Texas Southwestern Medical Center Completed No outcome recorded
Phase 1/2 NCT04160520 Oct 2019 → Jan 2023 urinary system disorder East Carolina University Completed No outcome recorded
Phase 1/2 NCT03035578 Dec 2017 → Jun 2018 The Hospital for Sick Children Withdrawn No outcome recorded
Phase 1/2 NCT03015246 Dec 2016 → Jun 2020 heroin dependence Wayne State University Completed No outcome recorded
Phase 1/2 NCT01975753 May 2014 → May 2018 University Hospital, Rouen Completed No outcome recorded
Phase 1/2 NCT01477190 Oct 2010 → Oct 2011 colon carcinoma, diverticulitis, inflammatory bowel disease McGill University Health Centre/Research Institute of the McGill University Health Centre Completed No outcome recorded
Phase 1/2 NCT01136356 Jul 2010 → Mar 2012 opiate dependence, opioid abuse Johns Hopkins University Completed No outcome recorded
Phase 234 trials
Phase 2 NCT07201987 Jan 2027 → Jan 2028 expected Ganesh M. Shankar Not yet recruiting No outcome recorded
Phase 2 NCT06837857 Apr 2025 → Jul 2029 expected chronic pain syndrome Mayo Clinic Recruiting No outcome recorded
Phase 2 NCT06716749 Dec 2024 → May 2025 osteoarthritis, knee Carilion Clinic Completed No outcome recorded
Phase 2 NCT05800834 Sep 2023 → Mar 2024 breast cancer, head and neck cancer Brazilian National Cancer Institute Unknown No outcome recorded
Phase 2 NCT05367336 Aug 2022 → Feb 2025 qualitative platelet defect Corewell Health South Terminated No outcome recorded
Phase 2 NCT05017246 Jan 2022 → Jul 2024 uterine corpus leiomyoma Washington University School of Medicine Terminated No outcome recorded
Phase 2 NCT05463367 Jan 2021 → Jun 2025 overdue chronic pain syndrome, opiate dependence, substance abuse Northwestern University Active not recruiting No outcome recorded
Phase 2 NCT05324995 Jan 2021 → Feb 2022 Isfahan University of Medical Sciences Completed No outcome recorded
Phase 2 NCT04358133 Dec 2020 → Oct 2022 acute respiratory failure Assistance Publique - Hôpitaux de Paris Completed No outcome recorded
Phase 2 NCT04582786 Dec 2020 → Jan 2022 Alaxia SAS Unknown No outcome recorded
Phase 2/36 trials
Phase 2/3 NCT03407404 Oct 2017 → Jun 2019 Makerere University Terminated No outcome recorded
Phase 2/3 NCT02967302 Aug 2015 → Dec 2021 osteoarthritis, knee Hildrun Haibel Unknown No outcome recorded
Phase 2/3 NCT03238430 May 2015 → May 2019 University Hospital, Lille Completed No outcome recorded
Phase 2/3 NCT02030717 Feb 2012 → May 2015 renal cell carcinoma Umeå University Completed No outcome recorded
Phase 2/3 NCT01837446 Jul 2011 → Jul 2012 stomatitis Isfahan University of Medical Sciences Completed No outcome recorded
Phase 2/3 NCT00982891 Mar 2010 → Jun 2012 chronic obstructive pulmonary disease Nova Scotia Health Authority Completed No outcome recorded
Phase 350 trials
Phase 3 NCT06593665 Sep 2024 → Dec 2026 expected testicular cancer Indiana University Recruiting No outcome recorded
Phase 3 NCT06349668 Apr 2024 → Oct 2027 expected congenital anomaly of kidney and urinary tract, kidney benign neoplasm, kidney cancer, ureter benign neoplasm +3 Hans Bahlmann Recruiting No outcome recorded
Phase 3 NCT05236647 Mar 2022 → Jan 2025 University Hospital, Akershus Completed No outcome recorded
Phase 3 NCT04429516 Dec 2020 → Mar 2023 idiopathic pulmonary fibrosis Royal Brompton & Harefield NHS Foundation Trust Completed No outcome recorded
Phase 3 NCT04188418 Oct 2020 → Aug 2027 expected cancer, hematopoietic and lymphoid cell neoplasm M.D. Anderson Cancer Center Active not recruiting No outcome recorded
Phase 3 NCT04455802 Oct 2020 → May 2021 neonatal abstinence syndrome Women and Infants Hospital of Rhode Island Withdrawn No outcome recorded
Phase 3 NCT04497831 Sep 2020 → Sep 2022 idiopathic pulmonary fibrosis Medical University of Gdansk Unknown No outcome recorded
Phase 3 NCT03948464 Dec 2019 → Jun 2020 substance-related disorder M. Eugenia Socias Terminated No outcome recorded
Phase 3 NCT03678792 Nov 2019 → Sep 2020 opiate dependence, substance withdrawal syndrome University of Alabama at Birmingham Withdrawn No outcome recorded
Phase 3 NCT03933397 Aug 2019 → May 2022 sickle cell disease Duke University Terminated No outcome recorded
Phase 499 trials
Phase 4 NCT07560501 Apr → Dec 2026 expected Tribhuvan University Teaching Hospital, Institute Of Medicine. Not yet recruiting No outcome recorded
Phase 4 NCT07288528 Apr 2026 → Apr 2029 expected hypersensitivity reaction disease McMaster University Not yet recruiting No outcome recorded
Phase 4 NCT07377630 Mar 2026 → Mar 2027 expected pregnancy disorder Gaslini Institute Not yet recruiting No outcome recorded
Phase 4 NCT07472959 Feb → May 2026 overdue cardiac valvular defect Istanbul University - Cerrahpasa Recruiting No outcome recorded
Phase 4 NCT06797973 Jul 2025 → May 2027 expected Anne Juul Wikkelsø Recruiting No outcome recorded
Phase 4 NCT06935708 Apr 2025 → Oct 2026 expected colorectal carcinoma Meri Mirceta Recruiting No outcome recorded
Phase 4 NCT06881563 Mar 2025 → Jul 2026 overdue colorectal cancer Meri Mirceta Not yet recruiting No outcome recorded
Phase 4 NCT06666985 Dec 2024 → Jun 2026 overdue First Affiliated Hospital, Sun Yat-Sen University Recruiting No outcome recorded
Phase 4 NCT06511232 Aug 2024 → Jul 2027 expected The Methodist Hospital Research Institute Recruiting No outcome recorded
Phase 4 NCT07386353 May 2024 → Jul 2026 overdue Hospital Central do Funchal Recruiting No outcome recorded
Phase not applicable86 trials
NCT07231926 Dec 2025 → Jun 2026 overdue Ataturk University Recruiting No outcome recorded
NCT07232108 Dec 2025 → Jun 2026 overdue Ataturk University Recruiting No outcome recorded
NCT07201272 Oct 2025 → Apr 2026 Tanta University Completed No outcome recorded
NCT07126483 Aug 2025 → Jan 2026 Ondokuz Mayıs University Completed No outcome recorded
NCT07023679 Jun 2025 → Jun 2029 expected acute myocardial infarction The Second Hospital of Anhui Medical University Recruiting No outcome recorded
NCT06990893 Jun 2025 → Oct 2026 expected Anqing Municipal Hospital Recruiting No outcome recorded
NCT06947135 May 2025 → Jun 2026 overdue acute myocardial infarction The Second Hospital of Anhui Medical University Recruiting No outcome recorded
NCT06837506 Feb → Aug 2025 overdue Ain Shams University Recruiting No outcome recorded
NCT06820190 Feb 2025 → Dec 2026 expected idiopathic scoliosis Tanta University Recruiting No outcome recorded
NCT06761989 Jan 2025 → Dec 2026 expected Seoul National University Hospital Recruiting No outcome recorded
Also used as a comparator or background therapy in 731 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 016 trials
Phase 0 NCT06854211 Comparator Jul 2026 → Jan 2027 expected obstructive sleep apnea syndrome, substance-related disorder Brigham and Women's Hospital Not yet recruiting No outcome recorded
Phase 0 NCT06617949 Comparator Jan 2025 → Dec 2027 expected substance-related disorder Medical College of Wisconsin Recruiting No outcome recorded
Phase 0 NCT06621849 Comparator Sep 2024 → May 2025 neuropathy, painful Cairo University Completed No outcome recorded
Phase 0 NCT06387303 Comparator Aug 2024 → May 2026 overdue University of Virginia Recruiting No outcome recorded
Phase 0 NCT05150756 Comparator Jan → Jul 2022 Ain Shams University Completed No outcome recorded
Phase 120 trials
Phase 1 NCT06882369 Comparator Nov 2024 → Jun 2025 overdue Minia University Active not recruiting No outcome recorded
Phase 1 NCT06653244 Comparator Apr → Dec 2024 Menoufia University Completed No outcome recorded
Phase 1 NCT06192589 Comparator Feb → Sep 2024 drug-induced liver injury Food and Drug Administration (FDA) Completed No outcome recorded
Phase 1 NCT05251376 Background Feb → Dec 2022 opiate dependence Lyndra Inc. Withdrawn No outcome recorded
Phase 1 NCT05143424 Comparator Nov 2021 → Sep 2023 substance-related disorder National Institute on Drug Abuse (NIDA) Unknown No outcome recorded
Phase 1/210 trials
Phase 1/2 NCT05257941 Comparator Jan 2022 → Aug 2024 Indiana University Terminated No outcome recorded
Phase 1/2 NCT05037539 Comparator Jun → Dec 2021 bone pain, periodic Department of Medical Services Ministry of Public Health of Thailand Completed No outcome recorded
Phase 1/2 NCT04033471 Comparator Jul 2019 → Mar 2021 Assiut University Unknown No outcome recorded
Phase 1/2 NCT03024957 Comparator Jan 2017 → Sep 2018 immunodeficiency disease Assiut University Unknown No outcome recorded
Phase 1/2 NCT02935933 Comparator Oct 2016 → Sep 2017 chronic pain syndrome Assiut University Unknown No outcome recorded
Phase 271 trials
Phase 2 NCT07657468 Background Jun → Oct 2026 expected National University of La Rioja Not yet recruiting No outcome recorded
Phase 2 NCT07533786 Comparator May → Nov 2026 expected Haisco Pharmaceutical Group Co., Ltd. Recruiting No outcome recorded
Phase 2 NCT07551739 Comparator Apr → Nov 2026 expected Haisco Pharmaceutical Group Co., Ltd. Not yet recruiting No outcome recorded
Phase 2 NCT07491146 Comparator Mar → Oct 2026 expected Yingyong Zhou,MD,PhD Not yet recruiting No outcome recorded
Phase 2 NCT06985290 Comparator Jul 2025 → Sep 2027 expected brain hypoxia - ischemia Ipsita Goswami Not yet recruiting No outcome recorded
Phase 2/327 trials
Phase 2/3 NCT06344169 Comparator May 2024 → Mar 2026 overdue chronic pain syndrome Dalin Tzu Chi General Hospital Recruiting No outcome recorded
Phase 2/3 NCT05375305 Comparator May 2022 → Oct 2023 Jiangsu HengRui Medicine Co., Ltd. Completed No outcome recorded
Phase 2/3 NCT04794738 Comparator Apr → Oct 2021 Jiangsu HengRui Medicine Co., Ltd. Unknown No outcome recorded
Phase 2/3 NCT04011163 Background Mar 2021 → Dec 2025 overdue respiratory underresponsiveness to hypoxia and hypercapnia KK Women's and Children's Hospital Active not recruiting No outcome recorded
Phase 2/3 NCT04589494 Comparator Apr 2020 → Feb 2021 chronic pain syndrome Assiut University Unknown No outcome recorded
Phase 3103 trials
Phase 3 NCT06940570 Comparator Jan 2028 → Aug 2029 aplastic anemia, bone marrow failure syndrome, leukemia, severe combined immunodeficiency University of Texas Southwestern Medical Center Suspended No outcome recorded
Phase 3 NCT07296770 Background Oct 2026 → Dec 2027 expected chronic pain syndrome University of California, San Francisco Not yet recruiting No outcome recorded
Phase 3 NCT06835504 Comparator Sep 2026 → Aug 2029 expected Columbia University Not yet recruiting No outcome recorded
Phase 3 NCT07076641 Background Jul 2026 → Jul 2027 expected digestive system disorder Ramsay Santé Not yet recruiting No outcome recorded
Phase 3 NCT07445737 Comparator Jun 2026 → Jun 2029 expected ST-elevation myocardial infarction Assistance Publique - Hôpitaux de Paris Not yet recruiting No outcome recorded
Phase 4255 trials
Phase 4 NCT07624006 Comparator Jan 2027 → Feb 2030 expected University Hospital, Strasbourg, France Not yet recruiting No outcome recorded
Phase 4 NCT07229495 Comparator Jul 2026 → Jun 2027 expected adolescent idiopathic scoliosis Peking Union Medical College Hospital Not yet recruiting No outcome recorded
Phase 4 NCT07525986 Comparator Apr 2026 → Mar 2027 expected Peking University First Hospital Recruiting No outcome recorded
Phase 4 NCT07423650 Background Mar → Oct 2026 expected Iuliu Hatieganu University of Medicine and Pharmacy Recruiting No outcome recorded
Phase 4 NCT07412223 Comparator Feb → Dec 2026 expected ileus, neuropathy, painful Xiangya Hospital of Central South University Not yet recruiting No outcome recorded
Show all 255 trials opens the full record — a long page
Phase not applicable229 trials
NCT06727435 Background Aug 2026 → Apr 2028 expected Beijing Tiantan Hospital Not yet recruiting No outcome recorded
NCT07712783 Background Jul → Sep 2026 expected Ondokuz Mayıs University Not yet recruiting No outcome recorded
NCT07658521 Background Jul → Dec 2026 expected Ain Shams University Enrolling by invitation No outcome recorded
NCT07695935 Comparator Jun → Oct 2026 expected Hitit University Recruiting No outcome recorded
NCT07584200 Comparator Jun 2026 → Mar 2027 expected osteoarthritis, hip Poznan University of Medical Sciences Not yet recruiting No outcome recorded
Show all 229 trials opens the full record — a long page

Evidence & citations 62 cited values

Every value below carries the sentence it was read from. 1,050 sources stand behind the page.

FieldValueCited text
Known as Morphine “The current double-blind, placebo-controlled in-patient study was designed to compare the effects of intravenously delivered fentanyl (0, 0.0625, 0.125, 0.187, and 0.250 mg/70...” PMID 17581533 Jun 2007
945

“All patients will be submitted to the institution's standard management: multimodal analgesia with common analgesic (dipyrone 4 to 8 g / day or paracetamol 1500 to 2250 mg /...” NCT07666178

“The tradition standard protocols involve the use of 0.3mg/kg of oral morphine about an hour before the start of the procedure before the start of the procedure to allow for the...” NCT05163366

“Postoperative patient controlled epidural analgesia (epidural cathterer inserted into Th7-8 intervertebral space, 200 ml of 0.125% levobupivacaine, 4 mg of morphine, 0.075 mg...” NCT05831761

“Intravenous morphine bolus doses of 2.5 mg or 5 mg may be administered for breakthrough pain when CPOT remains greater than 1 or when the treating clinician judges that pain is...” NCT06727435

“Intraoperative time: intravenous ketamine 0.5 mg kg-1, intravenous dexamethasone 8 mg Postoperative time: paracetamol 1 g every 6 hours a day, nefopam 20 every 8 hours a day,...” NCT06381063

“Injection Cocktail includes: 10mg Morphine, 30mg Ketorolac, 3.5ug/ml (385ug total) of Ropivicaine, 2.5ug /ml (275ug total) Epinephrine with the remainder of the solution made...” NCT01667445

“Tramadol 50mg IV bolus was firstly administered to the patients and if the NRS scale was not decreased at least about 2 points after 30 minutes, morphine 2mg IV was then...” NCT01526525

“To evaluate the levels of morphine in a patient's blood when morphine is given into the epidural space in the form of DepoDur® either alone or following a dose of lidocaine...” NCT00804609

“An intraoperative block of the genital branch of the genitofemoral nerve was performed in all patients in all three groups, followed by postoperative patient-controlled...” PMID 27487311 Jul 2016

“The patient is given one intrathecal dose of plain bupivacaine (Marcain® spinal) 5 mg/ml, 15 mg together with morphine (Morphine Special®) 0,4 mg/ml, 0.2 mg and clonidine...” NCT02026687

“The mixture contains 30ml (300mg) ropivacaine, 0.5ml (5 mg) morphine, 2 ml (50 mg) flurbiprofen and 0.5 ml of 1:1000 epinephrine, and then is diluted with 0.9% normal saline to...” NCT02784041

“rescue IV morphine 2-3 mg every 5-10 minutes titrated to NRS ≤ 3 for NRS ≥ 4, followed by morphine patient-controlled analgesia (1 mg bolus, 5-minute lockout, 10 mg/hour limit,...” NCT07658521

“Standard of Care analgosedation of choice using propofol, fentanyl, dexmedetomidine, morphine, hydromorphone, midazolam, or lorazepam administered according to the...” NCT06429657

“periarticular injection of 50 ml solution which contains ropivacaine 15 mg, epinephrine 0.3 mg, cefmetazole 1000mg, ketorolac 30 mg and morphine HCL 10mg before closure of...” NCT01112436

“Multimodal analgesia is administered to patients as follows : 2-3 mg of morphine (2mg if patient's weight \<60kg; 3mg if patient's weight \>60kg) + Paracetamol 1g/8h and...” NCT05673486

“Intravenous administration of paracetamol 1 g, morphine 0.1 mg/kg, dexamethasone 8 mg, and ketamine 0.5 mg/kg bolus followed by 0.3 mg/kg/h infusion for postoperative pain management.” NCT07455565

“Standard analgesia includes ketoprofen 100 mg twice daily and paracetamol 1000 mg every 8 hours for 24 hours after knee arthroplasty; morphine 10 mg IM as needed for rescue therapy.” NCT07059429

“Intrathecal 10 mg Heavy Marcaine, 200 mcg Morphine + High volume local anesthesia infiltration Bupivacaine 5mg/ml + adrenaline 5 mcg/ml 3mg/kg IBW diluted with 100cc Normal Saline” NCT03176758

“The peri-articular infiltration of multimodal agents will consist of 150 mg of levobupivacaine, 10 mg morphine and 30mg ketorolac diluted in 0.9% saline to make a volume 100 ml.” NCT01560767

“The cocktail, consists of triamcinolone 40 mg, marcaine 5 mg, and morphine 3 mg, is soaked in the gelfoam size 1x2 cm and applied on the epidura before removal of the endoscope.” NCT05738759

“experimental group (periarticular injection of bupivacaine, ketorolac, morphine, and epinephrine in saline; 80cc plus 1.3% liposomal bupivacaine 20cc; total injection 100cc).” PMID 28478185 Apr 2017

“Injection of 100 mcg of morphine, 15 mcg of fentanyl and 0.25 ml of normal salin (sterile) with 12 mg of bupivacaine in the intrathecal space to provide spinal anesthesia.” NCT05099055

“Intra-operative popliteal nerve block from the surgeon: 20mL 0.2% ropivacaine and a peri-articular injection of 10mg morphine, 30mg ketorolac and 40mg methylprednisolone.” NCT02219087

Morphine 5 mg, ropivacaine 150 mg, tramadol 40 mg, epinephrine 1 mg, ketorolac 60 mg, and ketamine 1 g will be mixed with normal saline to prepare a total volume of 60 ml” NCT06113497

“Prior to skin closing, IV morphine 0.1 mg/kg during skin closing and automated pupillometry measurement is repeated to aim pupillary diameter is within 20% of baseline.” NCT07614607

“After obtaining return of cerebrospinal fluid, hyperbaric bupivacaine 5 mg/mL 1,5 mL (7,5 mg) and morphine 200 µg/mL, 0.5 mL (100 µg) was injected intrathecally.” NCT06860893

“At any time, if a woman experienced pain despite the prescribed treatment, the next line of treatment was MIR (morphine immediate release, 10 mg tablet).” NCT04087317

“This study tests the effectiveness of a morphine-containing gel for reducing pain caused by pressure ulcers, also known as bedsores or pressure sores.” NCT00007254

“Periarticular infiltration solution containing 400 mg Ropivicaine, 30 mg Ketorolac, 5 mg Epidural Grade Morphine, and 0.6 ml of 1:1000 Epinephrine” NCT00869037

“The remifentanil administration will be piloted by the ANI, as well as the prophylactic administration of morphine at the end of the intervention.” NCT03618082

“Injection into capsular tissue after placement of the acetabular component: 0.5% Bupivacaine 15 cc 40 mg Solumedrol 10 mg Morphine 20 cc Saline” NCT02197273

“The patient-controlled anesthesia will be filled with morphine or hydromorphone. Pumps will be programmed be on demand only with no basal rate.” NCT03393117

“In the intrathecal morphine group, 100 micrograms of morphine (0.1 mL) will be added to the 12 mg of intrathecally administered bupivacaine.” NCT06612424

“intrathecal preservative free morphine (duramorph) 200 mcg with 7.5mg of hyperbaric bupivacaine was given for a patient 18-75 years of age” NCT05257941

“Local multimodal analgesia composition will include 5mg of morphine, 500 mg of epinephrine, 15mg of ketorolac, and 20mg of bupivacaine.” NCT05019638

“The patient was informed that the intravenous bolus of rescue morphine (4mg) was available every 4 hours if the pain was intolerable.” NCT04314505

“PCA opioid will include morphine OR hydromorphone (if patient has a sensitivity or is unable to tolerate or allergic to morphine).” NCT06940570

“Intra-operatively, opioids will be titrated to heart rate and spontaneous respiration rate e.g. fentanyl, morphine, hydromorphone.” NCT03471442

“bupivacaine HCl 80 mg, morphine 4 mg, epinephrine 300 micrograms, clonidine 100 micrograms, cefuroxime 750 mg, and normal saline” NCT00492973

“The unit's protocol includes drugs such as Morphine, Hydromorphone, Fentanyl, Clonidine, Ketamine, Midazolam and Acetaminophen.” NCT04538573

“supplemented with either thoracic epidural analgesia (TE Group) or oral morphine (OM Group) for postoperative pain management” PMID 37962202 Nov 2023

“Intravenous saline or morphine will be administered at the end of surgery in intervention or control groups, respectively.” NCT01872728

“Intravenous morphine solution 0.2 mg / ml in PCA mode without basal infusion, 1mg bolus demand and lockout of 8 minutes.” NCT01961895

Morphine PCA will be connected upon the first dose of study drug(roughly 30min prior to the completion of would suture).” NCT02811991

“Will be administered 3 ml of the investigational anesthetic in combination with morphine through the subarachnoid via.” NCT01994967

“patient is administered a PCIA with morphine boluses: 1.5-2 mg, lockout time :10 min, 1h limitation: 6-8 mg morphine.” NCT03975296

“From periarticular injection consisted of 400 mg ropivacaine, 5 mg morphine and 0.4 mg epinephrine in 50 cc solution.” NCT06557018

“classic anesthetic strategy with postoperative analgesia associating Paracetamol and Morphine with standardized dose.” NCT07149077

“10mg morphine in 5ml normal saline + 10ml of 0.25% bupivacaine ( total volume 15 ml) were injected intra-articularly” NCT04790292

“Epidural analgesia was continued for next 24 hours with a mixture of ropivacaine 2.2 mg/ml and morphine 0.4 mg/ml.” NCT04587505

“0.1 microgram morphine (IV) and diclofenac sodium 75 mg intramuscularly will perform for postoperative analgesia.” NCT04148729

“Intraoperative opioids (Fentanyl or Morphine) will be administered as deemed necessary by anesthesia care team.” NCT01500109

“Repeat doses of pain medication will be given as 0.05 mg/kg morphine or equivalent dose of opioid analgesic.” NCT02489630

“Intravenous morphine sulfate (0.05mg/kg) was given as a rescue medication if the VAS ≥ 4 for both groups.” NCT04482192

“Subjects with intolerance to oxycodone will receive the equivalent dosing of morphine as an alternative.” NCT06837857

“This arm is composed of Remifentanil hydrochloride and postoperative rescue analgesia will be morphine.” NCT05887258

“low-dose morphine (or an alternative opioid if allergic to morphine) at 0.025 mg/kg/dose every 4 hours.” NCT04291599

“3 nebulisations of 5 mg morphine chlorhydrate each given over 30 minutes (10 minutes per nebulisation)” NCT02156596

“IV morphine patient controlled analgesia (PCA) is being used in the postoperative period for 48 hours.” NCT02302586

“add Nefopam 30 mg ×3/day for moderate pain; morphine (Actiskenan) 5-10 mg every 4-6 h for severe pain” NCT07414706

“Both 2.5 µg sufentanil and 100 µg morphine were added to the local anaesthetic agent in both groups.” PMID 33428221 Jan 2021

“Patients in both groups will have PCA dilaudid or morphine prescribed for the post-operative period.” NCT03458598

“After methylnaltrexone or placebo administration, all patients received morphine (5 mg intravenous).” PMID 31377269 Jul 2019

“Postoperative analgesia was administered through a morphine the patient-controlled analgesia device.” NCT02645903

“conventional pain medications including narcotics (like morphine, etc.) and sedatives (like valium)” NCT02044302

“Parenteral morphine administered by bolus or patient-controlled analgesia to maintain pain control.” NCT01932554

“Hydromorphone Patient Controlled Analgesia (PCA),Preservative free Morphine via epidural for 36hrs” NCT06617949

“This classic patient-controlled IV-pump contains 1mg/ml morphine and 50mcg/ml dehydrobenzperidol.” NCT03036514

“The injection contained 150mg bupivacaine (3mg/mL), 60mg ketorolac(1.2mg/mL) and 1mg morphine.” NCT06630520

“Intravenous patient controlled analgesia with morphine(1mg/ml)for post operative pain control” NCT01929915

“Combination of paracetamol + non-steroidal anti-inflammatory drug + morphine to all patients” NCT03639389

“Intravenous patient controlled analgesia with morphine 1mg/ml for postoperative pain control” NCT04079673

Morphine (MO) is the most commonly used opioid for the treatment of post-surgical pain (14).” NCT00849719

“Oral Opioids (Codeine, Tramadol, Hydrocodone, Oxycodone, Methadone, Morphine, Hydromorphone)” NCT03472469

“iv morphine with patient controlled analgesia (1 mg demand bolus dose, 20 min lockout time)” NCT02778958

Morphine analgesia controlled by the patient will begin 2 hours after tracheal extubation” NCT05322603

“A mixture of 5% ketamine and 5% morphine will be prepared in a 100 cc bag of 0.9% saline.” NCT06774274

“5mg morphine, 500 micrograms epinephrine, and 4ml normal saline (superficial injection).” NCT05037812

morphine (administered intravenously at a dosage of 2-4 mg, up to a maximum dose of 8 mg” NCT06653244

“followed by morphine 0.05 mg/kg ABW after intubation and nasal decongestant application” NCT07299630

“Standardized spinal mixture of 10.25 mg hyperbaric bupivacaine, and 0.125 mg morphine.” NCT06418308

“Patients allocated to this group receive a combination of Morphine and Dexmedetomidine” NCT03936205

“isobaric bupivacaine 0.5% 10 mg together with preservative-free morphine was injected.” NCT01477190

Morphine 0.1 mg/kg PRN will be administered every 8 hours for postoperative analgesia” NCT04648540

“IV-PCA programmed with morphine boluses of 2-3 mg and a lock-out time of 5-15 minutes” NCT01541137

“The intravenous injection of morphine using the patient-controlled analgesia machine” NCT01991275

“For patients with a FLACC score of 6-10, morphine (0.05mg/kg) will be administered.” NCT03467750

“Patients will receive IV morphine 0.1mg/kg after induction of general anesthesia.” NCT06584695

“use of IV propofol for sedation and morphine, the drug of choice for cardiac pain” NCT02546765

“* Morphine 7.5 mg by mouth every four to six hours as needed for pain, 10 doses” NCT05722002

“Drug: Morphine will be injected in the subarachnoid space with a dose of 100 μg” NCT03849508

“with morphine 250mic and atropine sulphate 100 micwith total volume = 2.5 ml” NCT05137288

“400 mg Ropivacaine, 5 mg morphine, and 0.4 mg epinephrine in 100 cc solution” NCT02369523

“In Morphine group, patients will receive morphine as needed after surgery.” NCT03854851

“One group will receive bupivacaine 15 mg and morphine 100 ug intrathecally” NCT05406765

“Postoperative morphine 0.03 mgr / kgr / weight was administered if EVA ≥4” NCT02239497

“Group treated with intravenous Patient-Controlled Analgesia with MorphineNCT05259098

“Bupivacaine 0.25% + midazolam 5mg and morphine 5mg in total volume 10ml” NCT04033471

“Opioids: heroin, morphine, oxycodone, hydrocodone, methadone, codeine” NCT02033707

“IV Ketamine 0.1 mg/kg with IV morphine -0.1 mg/kg with IM Sailne 0.9%” NCT04013958

“Receive Morphine Patient Controlled Analgesia + NSAIDs + Paracetamol” NCT06750627

“positive result 10μg/kg morphine; negative result 50μg/kg morphine.” NCT02990910

“* IV Morphine (or Dilaudid): 1 or 2 mg q 2hr prn breakthrough pain” NCT02219581

morphine given by PCA (patient-controlled analgesia) at 1 mg/dose” NCT05069311

Morphine every 4 hours as needed for up to a maximum of 5 days” NCT03429400

“IV morphine-PCA will be applied postoperatively for 24 hours .” NCT06630858

Morphine (Apokyn®, Avinza®, Kadian®, MS-Contin®, among others)” NCT06240390

“Intrathecal spinal morphine (5 mcg / kg) immediately post-op” NCT03537612

“Intrathécale morphine is used for post-cesarean pain control” NCT01211431

morphine 150 mcg will be used by intrathecal administration” NCT04814745

Morphine 0.1-0.12mg/kg, Fentanyl 1-2mcg/kg during induction” NCT04894864

“1 ml morphine sulfate 10 mg/ml (DarouPakhsh, Tehran, Iran)” NCT05324995

“A base low dose opioid of 5mg morphine I.V every 8 hours.” NCT03193658

Morphine medications are the mainstay of pain management” NCT05515809

“using ropivacaine, epinephrine, ketorolac, and morphinePMID 24706022 Jan 2015

“In case of opioid use, morphine treatment is preferred.” NCT04745520

“patient-controlled intravenous analgesia with morphinePMID 28178436 Jan 2017

“Continuous morphine/midazolam and 'as needed' doses.” NCT02112448

“IV analgesia, typically Morphine/Opioid medications” NCT04892563

“Examples of opioids are morphine and hydromorphone.” NCT04221165

“bolus dose 2,5 mg i.v. morphine, 15 minutes lockout” NCT02576223

Morphine, oxycodone, metadone, fentanyl, tramadol” NCT03365817

“Intravenous analgesia is performed with morphine.” NCT03012945

“with tramadol and/or morphine provided as rescue.” NCT07337135

“Post-operative morphine IV for breakthrough pain” NCT06935331

“IV paracetamol 1 g/6 h + IV PCA morphine rescue” PMID 28192892 Feb 2017

“Rescue opioids if VAS\>4: Adolonta or MorphineNCT07558226

“0.1 mg/kg morphine intravenous pre operative” NCT06935006

“Patients will receive morphine 0.1 mg/kg” NCT04402411

morphine 0.1 mg/kg IV every six hours” NCT05393414

morphine sulphate sustained release” NCT04132011

“Intravenous morphine bolus of 3 mg” NCT00874172

“Desflurane, Morphine, Paracetamol” NCT05172739

“slow-release oral morphine (SROM)” NCT01079117

“100 µ of intrathecal MorphineNCT02711072

Morphine Sulfate0.1 Mg/Kg Iv” NCT01465984

“5 mg morphine intravenously” NCT02627950

“Epidural morphine 4mg bolus” NCT00848419

“intrathecal morphine 100mcg” NCT03518463

“Intrathecal morphine (ITM)” NCT03261193

“ITM (Intrathecal Morphine)” NCT06666985

Morphine, Pain intensity” NCT01541124

“Epidural Morphine 150ug” NCT01511627

“Midazolam and morphineNCT00416039

“intranasal morphineNCT00474799

“0.1 mg/kg morphineNCT05752799

Morphine 1 mg/ml” NCT01367418

Morphine Sulfate” NCT07296770

“PCA, morphineNCT00880529

morphineNCT04234516

MorphineNCT02785003

morphineNCT05463367

MorphineNCT02132416

morphineNCT01705288

MorphineNCT02886286

NCT00158873

NCT04448561

NCT07104097

NCT02362022

NCT05843344

NCT01095575

NCT03774836

NCT06942702

NCT03596060

NCT01835262

NCT03158584

NCT05317572

NCT02687347

NCT00195910

NCT03199170

NCT01094522

NCT00196131

NCT01904071

NCT02781415

NCT00923000

NCT03010540

NCT01369186

NCT01249872

NCT05848635

NCT04527393

NCT06417268

NCT00472303

NCT00553553

NCT07445737

NCT01549002

NCT04528173

NCT01179191

NCT01837394

NCT01244126

NCT01833715

NCT07231926

NCT04528563

NCT02856698

NCT03365115

NCT05853263

NCT01837446

NCT07442877

NCT01906073

NCT00921102

NCT04188418

NCT05308420

NCT03511833

NCT06570343

NCT03622489

NCT02238340

NCT07451522

NCT05639712

NCT03933397

NCT01838707

NCT02976597

NCT00718406

NCT00839787

NCT01939379

NCT06572241

NCT01549652

NCT04766463

NCT00875550

NCT00782951

NCT02726828

NCT02460913

NCT00004696

NCT00783016

NCT02530151

NCT03396588

NCT06947135

NCT00477061

NCT02151682

NCT05325164

NCT06172920

NCT05831449

NCT02056301

NCT01422291

NCT03434951

NCT01304212

NCT01304134

NCT00478023

NCT07452705

NCT01940224

NCT01245244

NCT02028923

NCT02935933

NCT00982618

NCT03525509

NCT06761989

NCT07094802

NCT04764825

NCT06464146

NCT01502644

NCT00872885

NCT07232108

NCT02460640

NCT02689024

NCT01906762

NCT06331143

NCT03051022

NCT01312415

NCT03435692

NCT00982891

NCT01900847

NCT06949852

NCT02440399

NCT03117894

NCT06344169

NCT01452789

NCT01830296

NCT00415597

NCT02462577

NCT03502642

NCT04886453

NCT04700007

NCT02091297

NCT00784472

NCT02064894

NCT00892606

NCT00374881

NCT00237731

NCT05474040

NCT06935708

NCT05331781

NCT00558090

NCT04533243

NCT02954484

NCT01828840

NCT06326983

NCT04887649

NCT00558870

NCT02820324

NCT02625181

NCT03045133

NCT01546701

NCT06422182

NCT06349668

NCT00636415

NCT05630222

NCT01671410

NCT02187614

NCT07186426

NCT03887260

NCT05338320

NCT03241485

NCT03431285

NCT01298297

NCT03648008

NCT04772222

NCT02164825

NCT00256347

NCT02314871

NCT00270322

NCT01552148

NCT03012971

NCT02152410

NCT04609033

NCT04445636

NCT00640042

NCT03926559

NCT00293969

NCT02913469

NCT06411665

NCT03012984

NCT00916890

NCT03013075

NCT02912195

NCT02284282

NCT01958476

NCT04061330

NCT03619785

NCT04761302

NCT01825993

NCT01366313

NCT05813847

NCT03875274

NCT03098420

NCT03117595

NCT00378937

NCT03777644

NCT07712783

NCT02223377

NCT02914015

NCT02416115

NCT00878371

NCT02152514

NCT02731430

NCT02353754

NCT06854211

NCT01296334

NCT01823497

NCT01984463

NCT07472959

NCT02531165

NCT00547664

NCT06319859

NCT05186454

NCT00199316

NCT02936934

NCT02300194

NCT02327923

NCT02282956

NCT03874091

NCT03982784

NCT05659823

NCT03428880

NCT00289419

NCT05105074

NCT02223533

NCT06409689

NCT00231517

NCT01186445

NCT03428633

NCT02666794

NCT05117034

NCT01362998

NCT05069012

NCT06186141

NCT04455802

NCT01966172

NCT06479655

NCT06315959

NCT06407544

NCT03357393

NCT06593665

NCT03041948

NCT03041935

NCT07425678

NCT01844206

NCT00991627

NCT03282669

NCT06315920

NCT07229495

NCT03801629

NCT00672347

NCT01675622

NCT02236130

NCT00625911

NCT00992082

NCT05350696

NCT00831051

NCT01236495

NCT05006079

NCT03580980

NCT02810782

NCT03990922

NCT05351229

NCT00338481

NCT06458400

NCT04214834

NCT00200590

NCT01112540

NCT02793947

NCT02868944

NCT01602640

NCT02540070

NCT00155376

NCT00155233

NCT01318161

NCT02458742

NCT07076641

NCT00201539

NCT03427463

NCT06728371

NCT04635852

NCT03007121

NCT02115087

NCT00000335

NCT02173756

NCT03715517

NCT04755712

NCT02299349

NCT02825056

NCT03238430

NCT01234272

NCT05439564

NCT04672382

NCT07423910

NCT03580187

NCT00410540

NCT03015246

NCT00994383

NCT02819661

NCT03257319

NCT07330479

NCT00004390

NCT01507233

NCT03006627

NCT07201272

NCT03403842

NCT02939235

NCT02504996

NCT02288923

NCT03529097

NCT02939248

NCT07201987

NCT02252926

NCT00934661

NCT02962024

NCT07491146

NCT06192589

NCT02289261

NCT00996177

NCT01816581

NCT01816243

NCT02605187

NCT06298370

NCT01933542

NCT04160520

NCT02198378

NCT07203794

NCT01318187

NCT01084473

NCT01595867

NCT03570541

NCT04589429

NCT01508455

NCT00880373

NCT02523846

NCT00460239

NCT00142519

NCT05208801

NCT00880607

NCT00634010

NCT06716749

NCT04442919

NCT00656773

NCT00287326

NCT01543165

NCT04752033

NCT00562627

NCT02135120

NCT03513445

NCT02566226

NCT06715657

NCT00609466

NCT03404908

NCT03017248

NCT05506930

NCT03209427

NCT01084161

NCT00142896

NCT02669004

NCT00383682

NCT07246785

NCT03713216

NCT05218733

NCT00795223

NCT07164677

NCT05367336

NCT07164664

NCT00003687

NCT00125684

NCT01159262

NCT05217160

NCT03823534

NCT01680939

NCT03967327

NCT03682211

NCT02456909

NCT02566096

NCT02749409

NCT07071012

NCT02749162

NCT02095366

NCT03451695

NCT00346268

NCT03425084

NCT04582786

NCT06985290

NCT01914042

NCT05372133

NCT01681264

NCT02213159

NCT05374356

NCT05375305

NCT02591017

NCT02339766

NCT03865004

NCT04427826

NCT04824274

NCT06837506

NCT00702416

NCT03165383

NCT03005548

NCT00701909

NCT03236805

NCT02135055

NCT01882530

NCT01809106

NCT06609993

NCT03824834

NCT07207304

NCT02078089

NCT01533155

NCT00797264

NCT05042817

NCT02765815

NCT05073744

NCT03254459

NCT01430182

NCT01281891

NCT05379374

NCT05688371

NCT02571491

NCT02200185

NCT00772187

NCT04234516

NCT03437707

NCT03786562

NCT03579446

NCT01322191

NCT02096003

NCT02483221

NCT02698228

NCT03825198

NCT01997788

NCT04497831

NCT02456142

NCT01807429

NCT01953978

NCT02017314

NCT00385541

NCT00349401

NCT03288428

NCT02769325

NCT06990893

NCT02279628

NCT05696678

NCT01878006

NCT01918917

NCT06784180

NCT03678792

NCT02746263

NCT07516717

NCT02085577

NCT01119222

NCT02622126

NCT05880017

NCT01082471

NCT04243954

NCT04030442

NCT06875791

NCT01804075

NCT07412223

NCT02860949

NCT04388111

NCT01522534

NCT01465191

NCT02815709

NCT05281081

NCT00362219

NCT02924974

NCT00726830

NCT03407404

NCT03224039

NCT03726268

NCT06076759

NCT03355716

NCT01593280

NCT06076018

NCT00726999

NCT07525986

NCT04248608

NCT00305058

NCT02698995

NCT05591417

NCT04429516

NCT05590559

NCT03825887

NCT04246697

NCT03586934

NCT05429489

NCT02217878

NCT01080911

NCT02381717

NCT05702151

NCT02277678

NCT03036384

NCT06704139

NCT07695935

NCT05588336

NCT05602038

NCT02511483

NCT05587998

NCT06070701

NCT07126483

NCT03324815

NCT06204120

NCT02620631

NCT03968146

NCT01079754

NCT02473276

NCT00728832

NCT02790099

NCT03151369

NCT02971475

NCT00306020

NCT07533786

NCT01077752

NCT03675646

NCT00403663

NCT05704673

NCT06205875

NCT02558010

NCT02673372

NCT00487084

NCT07536594

NCT04256642

NCT02498171

NCT03607916

NCT03908060

NCT06065956

NCT02411149

NCT06621849

NCT07678073

NCT04574479

NCT00943566

NCT00388011

NCT00488969

NCT05076773

NCT00020618

NCT03225690

NCT06826742

NCT06797973

NCT04403724

NCT01917448

NCT06511232

NCT01123551

NCT04104204

NCT05905367

NCT07054775

NCT04104646

NCT00580489

NCT01794689

NCT01071499

NCT02880540

NCT01201499

NCT02880800

NCT05908851

NCT01071057

NCT02848599

NCT04475029

NCT01686802

NCT05017246

NCT00357942

NCT02848729

NCT03616639

NCT04852484

NCT02434939

NCT04852003

NCT06881563

NCT01718496

NCT00820027

NCT05236647

NCT02801838

NCT05913284

NCT07050277

NCT03203967

NCT03035578

NCT02435537

NCT07666971

NCT02600715

NCT05092828

NCT01790971

NCT03034382

NCT00528177

NCT03275012

NCT00737997

NCT06882369

NCT07666009

NCT01734551

NCT07002788

NCT01016808

NCT00802308

NCT05582135

NCT02014714

NCT04476173

NCT00681174

NCT00494429

NCT05920642

NCT00910208

NCT00527332

NCT04651595

NCT00390039

NCT05037539

NCT01066247

NCT00768183

NCT01275547

NCT03470675

NCT02467556

NCT00818493

NCT00803114

NCT01378949

NCT01021696

NCT00266539

NCT07551739

NCT00803283

NCT03948464

NCT01513564

NCT01738100

NCT07657468

NCT02641301

NCT02397330

NCT06681805

NCT04369950

NCT05270434

NCT05413902

NCT04691726

NCT00390312

NCT01951963

NCT06042426

NCT03751423

NCT00695045

NCT04368364

NCT03249558

NCT06901830

NCT02001948

NCT03700411

NCT02716129

NCT03634111

NCT01219088

NCT03386630

NCT07008443

NCT04292990

NCT00219921

NCT04794738

NCT01219062

NCT02264821

NCT06680466

NCT03078946

NCT02773472

NCT02782273

NCT03232957

NCT05939635

NCT00759902

NCT04279054

NCT02067338

NCT02789410

NCT03063359

NCT04358133

NCT07642193

NCT06036979

NCT04729049

NCT02449954

NCT07560501

NCT02577809

NCT00613743

NCT01205516

NCT01146457

NCT05150756

NCT00815022

NCT02967172

NCT01057381

NCT05723341

NCT03834363

NCT02817321

NCT02995304

NCT04849455

NCT01380093

NCT01975753

NCT01055015

NCT07568405

NCT00521248

NCT01869036

NCT02586454

NCT01539538

NCT03585374

NCT02267304

NCT00759954

NCT00184938

NCT02677532

NCT06021717

NCT00504283

NCT07629323

NCT01917045

NCT04017442

NCT04115462

NCT00353704

NCT02036697

NCT01053039

NCT01129934

NCT04298853

NCT03700541

NCT02841982

NCT07012590

NCT04785768

NCT00733083

NCT03024957

NCT02009722

NCT01339624

NCT02410317

NCT06010056

NCT02267772

NCT00573937

NCT03383588

NCT02469077

NCT03473093

NCT05031234

NCT00505414

NCT07377630

NCT04119037

NCT03839160

NCT05248724

NCT01536301

NCT02426164

NCT07378904

NCT01866254

NCT00213200

NCT00244153

NCT04342130

NCT02804126

NCT00246532

NCT02430818

NCT04304274

NCT02658149

NCT00761085

NCT02929147

NCT02100748

NCT06820190

NCT05137184

NCT04138615

NCT02782286

NCT02248493

NCT01538745

NCT02804022

NCT03592992

NCT02677571

NCT03379987

NCT01476124

NCT05251376

NCT03134703

NCT06442995

NCT02293525

NCT02741076

NCT02035904

NCT02137525

NCT01690780

NCT02145975

NCT02083315

NCT03068260

NCT05143424

NCT04011163

NCT03664622

NCT01691690

NCT06653439

NCT01977898

NCT02082067

NCT05558397

NCT01134848

NCT02817477

NCT02708459

NCT00264485

NCT07386353

NCT06387303

NCT02146638

NCT03843281

NCT00955877

NCT01689597

NCT02292667

NCT05023473

NCT04313374

NCT03846102

NCT02603848

NCT01037335

NCT02429050

NCT00314340

NCT01536964

NCT01380197

NCT01766960

NCT01566253

NCT01038609

NCT02947243

NCT02851303

NCT03564548

NCT00513864

NCT02335294

NCT01924234

NCT05742438

NCT01136356

NCT06890533

NCT00009672

NCT03230474

NCT02292082

NCT01979354

NCT04009759

NCT05742958

NCT07023679

NCT03730714

NCT07023497

Known as Actiskenan “morphine (Actiskenan) 5-10 mg every 4-6 h for severe pain” NCT07414706
Known as Apokyn “Morphine (Apokyn®, Avinza®, Kadian®, MS-Contin®, among others)” NCT06240390
Known as Avinza “We would like to learn if a medicine called "modified-release morphine sulfate" (Avinza) helps reduce Spinal Cord Injury (SCI)-related pain that has lasted a long time.” NCT00488969
2

“Morphine (Apokyn®, Avinza®, Kadian®, MS-Contin®, among others)” NCT06240390

Avinza (morphine sulfate sustained-release) capsules” NCT00782548

Known as Chlorhydrate of Morphine “Doses of 1 mg of Chlorhydrate of Morphine will be delivered intravenously by the Patient Controlled Analgesia (PCA) pump.” NCT02292667
Known as DepoDur “The primary purpose of this study is to evaluate the effects of lidocaine/epinephrine test dose administration on the PK profile of a single epidural dose of DepoDur...” NCT00728832
4

NCT00335517

NCT00895531

NCT00456638

NCT00762554

Known as Depolan Depolan (morphine), Ebixa (memantine)” NCT02467556
Known as Dimorf DimorfNCT05800834
Known as Duramorph “Intrathecal preservative free morphine (duramorph) 200 mcg with 7.5mg of hyperbaric bupivacaine placed by a spinal needle prior to induction of general anesthesia (n=71)” NCT06593665
8

“Multimodal local injection of bupivacaine (Marcaine), morphine sulfate (Duramorph), ketorolac (Toradol) given at the fracture site at the time of hip fracture surgery” PMID 37199438 Sep 2023

“intrathecal preservative free morphine (duramorph) 200 mcg with 7.5mg of hyperbaric bupivacaine was given for a patient 18-75 years of age” NCT05257941

“preservative free morphine (Duramorph)” NCT05506930

NCT02143141

NCT01298778

NCT06114121

NCT02734940

NCT03853694

Known as Egalet morphine “Egalet® morphine, Controlled Release 30 mg Oral tablet once daily for 2 weeks and MST Continus® 15 mg twice daily for 2 weeks” NCT00446069
1

“Single dose administration of Egalet® morphine with alcohol” NCT00802308

Known as EREM “The primary objective was to evaluate the serum pharmacokinetic profile of a single 15-mg dose of extended-release epidural morphine (EREM) administered at the lower thoracic...” PMID 19840530 Nov 2009
2

“Extended-release Epidural morphine (EREM) 80” NCT00955877

“Extended Release Epidural Morphine (EREM)” NCT00934661

Known as Immediate release morphine Immediate release morphine, solution Dosage: Start with a minimum of 5mg (to be determined by titration)” NCT04635852
Known as intra spinal morphine intra spinal morphineNCT00695045
Known as Intrathecal morphine ClinicalTrials.gov intervention name — accepted as the source's own label NCT01312077
2

NCT07584200

NCT03263689

Known as IRM “immediate-release morphine (IRM) as solution or tablet is most frequently used in clinical practice to treat episodic breathlessness.” NCT04635852
Known as ITM “This randomized double-blind trial investigates the relative contributions of adductor canal block and low-dose intrathecal morphine (ITM) to postoperative analgesia and...” PMID 29315129 Feb 2018
6

“Intrathecal morphine (ITM) and continuous wound infiltration (CWI) are two alternatives to thoracic epidural analgesia in major abdominal surgery” PMID 42403225 Jul 2026

“Erector Spinae Plane Block (ESPB) and intrathecal morphine (ITM) provide adequate postoperative (PO) analgesia.” PMID 40047853 Mar 2025

“120 mcg intrathecal morphine (ITM) will be administered to the morphine group.” NCT06076018

“Intrathecal morphine sulfate (ITM)” NCT04368364

“Intrathecal morphine (ITM)” NCT03261193

ITM (Intrathecal Morphine)” NCT06666985

Known as IVMS IVMS (IV Morphine)” NCT01904071
Known as KADIAN “a test formulation of morphine sulfate 200 mg sustained-release capsules manufactured by Alpharma Branded Products Division Inc. to an equivalent oral dose of the commercially...” NCT00759356
5

“Morphine (Apokyn®, Avinza®, Kadian®, MS-Contin®, among others)” NCT06240390

KADIAN (morphine sulfate sustained-release) capsules” NCT00782548

KADIAN (morphine sulfate sustained-release) capsules” NCT00759954

KADIAN (morphine sulfate extended-release) capsules” NCT00759915

KADIAN (morphine sulfate extended-release) capsules” NCT00759902

Known as MIR “At any time, if a woman experienced pain despite the prescribed treatment, the next line of treatment was MIR (morphine immediate release, 10 mg tablet).” NCT04087317
Known as MNS075 “Intranasal (IN) Morphine Nasal Spray (MNS075) 7.5 mg and 15 mg” NCT00390039
2

“Intranasal Morphine (MNS075) 3.75 mg” NCT00388011

MNS075 (Intranasal Morphine)” NCT00474799

Known as MOR “Patients were consented and randomized to receive, either IV ketamine (LDK) 1 mg/kg or IV morphine (MOR) 0.1 mg/kg as an infusion over 10 min.” PMID 29794277 Jan 2018
Known as Morfin “spinal injection of 12 mg bupivacain,160 ug morfin och klonidin, according to age” NCT02030717
3

MorfinNCT02094807

NCT07426692

NCT05956275

Known as Morfina cloridrato 10 mg /ml - Morphine Morfina cloridrato 10 mg /ml - MorphineNCT01249872
Known as Morfini Sulfas WZF “postoperative rescue opioid analgesia will be administered intravenously using 2 miligrams of morphine ((Morfini Sulfas WZF, 20mg/ml, solutio pro iniectione, Polfa Warszawa, Poland)” NCT06609993
Known as Morphin morphine hydrochloride (morphine hydrochloride 2 mg/ml, Morphin® Nycomed Austria GmbH, St. Peter Strasse 25, A-4021, Linz, Austria)” NCT01084473
1

MorphinNCT00878293