Combination of Peripheral Nerve Block and DepoDur in Total Knee Joint Replacement

Summary

The investigators hypothesize that patients who receive a femoral catheter with low dose epidural Depodur will experience comparable or superior pain relief than those who receive both femoral and sciatic catheters. In addition, the investigators hypothesize that the one catheter will be less time consuming to place and facilitate early ambulation of the patient.

Timeline

Start

2009-12

Primary completion

2012-12

Completion

2012-12

Outcome

Missed primary endpoint

Stopped: “Investigator left institution”

registry analysis (superiority test); Peripheral Nerve Group vs Depodur Group; p = 0.95; t-test, 2 sided NCT00895531 ↗

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Morphine	Other / unclassified	7.5 mg	Other

Indications