drugset / Trial / NCT03933397

Comparing Individualized vs. Weight Based Protocols to Treat Vaso-Occlusive Episodes in Sickle Cell Disease

NCT03933397

RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this research study is to compare two different ways to give opioid pain medicine to treat sickle cell disease pain that is bad enough to go to the emergency department for treatment. One way uses your weight to decide how much pain medicine to give you while in the emergency department. This is called weight based treatment. The other way uses how much pain medicine you take at home and how much medicine you needed during past emergency department visits to decide how much medicine to give you. This is called patient specific treatment.

Timeline

Start
2019-08-13
Primary completion
2022-05-13
Completion
2022-05-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Hydromorphone Other / unclassified 1 mg
Subject Hydromorphone Other / unclassified 1.5 mg
Subject Hydromorphone Other / unclassified 2 mg
Subject Morphine Other / unclassified 4 mg
Subject Morphine Other / unclassified 6 mg
Subject Morphine Other / unclassified 8 mg
Subject Morphine Other / unclassified 10 mg

Indications