drugset / Trial / NCT06837857

Prescription Opioids, Brain Structure, and Cognition in Older Adults With Chronic Pain

NCT06837857

Phase 2 Recruiting 200 enrolled Mayo Clinic
RandomizedParallel-groupQuadruple-blindOther

Summary

The purpose of this study is to determine whether exposure to prescription opioids is associated with brain structural changes on magnetic resonance imaging (MRI), with the primary outcome of white matter integrity as measured by fractional anisotropy of the corpus callosum.

Timeline

Start
2025-04-16
Primary completion
2029-07-01
Completion
2029-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Morphine Other / unclassified
Subject Oxycodone Other / unclassified Oral

Indications