drugset / Trial / NCT06837857
Prescription Opioids, Brain Structure, and Cognition in Older Adults With Chronic Pain
RandomizedParallel-groupQuadruple-blindOther
Summary
The purpose of this study is to determine whether exposure to prescription opioids is associated with brain structural changes on magnetic resonance imaging (MRI), with the primary outcome of white matter integrity as measured by fractional anisotropy of the corpus callosum.
Timeline
- Start
- 2025-04-16
- Primary completion
- 2029-07-01
- Completion
- 2029-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Morphine | Other / unclassified | — | — |
| Subject | Oxycodone | Other / unclassified | — | Oral |