drugset / Trial / NCT01536964
The Effect of Morphine on Prasugrel Absorption in STEMI Patients
Phase 4
Completed
12 enrolled
Sheffield Teaching Hospitals NHS Foundation Trust
National Institute for Health Research, United Kingdom · collab
RandomizedCrossoverOpen-labelOther
Summary
Heart Attacks are a major cause of death in this country. When patients have a heart attack, they are treated with anti-clotting drugs, one of which is a drug called Prasugrel. It is important that Prasugrel starts to work as quickly as possible following a heart attack. As many patients who have a heart attack experience excruciating pain, they are often given morphine (a strong painkiller) by the Ambulance crew. We think that morphine may affect how Prasugrel is absorbed from the stomach and may delay how quickly it starts to work. We intend to study the effect of morphine on the absorption of Prasugrel.
Timeline
- Start
- 2012-04
- Primary completion
- 2013-03
- Completion
- 2013-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Morphine | Other / unclassified | 2.5 mg | — |