drugset / Trial / NCT05393414
Efficacy of NSAID and Acetaminophen in the Control of Post-Operative Pain in Patients Undergoing Total Knee Replacement
RandomizedParallel-groupTriple-blindTreatment
Summary
An alternate perioperative pain control protocol composed of intravenous ketorolac and oral acetaminophen for patients who underwent total knee replacement was designed with the aim to determine its efficacy when compared to pain control with intravenous morphine and oral oxycodone combined with acetaminophen. In addition, the study will evaluate the differences and similarities in the Hispanic population that could predict protocol efficacy.
Timeline
- Start
- 2019-11-25
- Primary completion
- 2020-03-12
- Completion
- 2020-03-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Acetaminophen | Small molecule | 650 mg | Oral |
| Subject | Acetaminophen | Small molecule | 1 g | Oral |
| Subject | Ketorolac | Other / unclassified | 15 mg | Intravenous |
| Subject | Ketorolac | Other / unclassified | 30 mg | Intravenous |
| Subject | Morphine | Other / unclassified | 0.1 mg/kg | Intravenous |
| Subject | Oxycodone | Other / unclassified | 5 mg | Oral |
Indications
No indication recorded.