drugset / Trial / NCT03015246

Effects of Buprenorphine/Naloxone Dose on Experimental Stress Reactivity and Opioid Abstinence

NCT03015246

Phase 1/2 Completed 26 enrolled Wayne State University
RandomizedCrossoverDouble-blindBasic science

Summary

This research deals with behaviors that are part of opioid dependence. The purpose is to study how stress and medication dose can affect opioid drug use.

Timeline

Start
2016-12
Primary completion
2020-06
Completion
2020-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Buprenorphine/Naloxone Unknown 1.4 mg Other
Subject Buprenorphine/Naloxone Unknown 4.2 mg Other
Subject Buprenorphine/Naloxone Unknown 12.8 mg Other
Subject Hydrocortisone Other / unclassified 20 mg Oral
Subject Morphine Other / unclassified
Subject Yohimbine Small molecule 60 mg Oral

Indications