Efficacy and Safety of EXPAREL Versus Standard of Care (SoC) in Subjects Undergoing Elective Cesarean Section

Phase 4 Completed 167 enrolled Pacira Pharmaceuticals, Inc

RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to compare total opioid consumption by subjects in different treatment groups. Another purpose of this study is to assess how well EXPAREL works, collect any safety data and assess your satisfaction using EXPAREL.

Timeline

Start: 2019-03-04
Primary completion: 2020-01-09
Completion: 2020-01-16

Publications

Habib AS, Nedeljkovic SS, Horn JL, Smiley RM, Kett AG, Vallejo MC, Song J, Scranton R, Bao X. Randomized trial of transversus abdominis plane block with liposomal bupivacaine after cesarean delivery with or without intrathecal morphine. J Clin Anesth. 2021 Dec;75:110527. doi: 10.1016/j.jclinane.2021.110527. Epub 2021 Oct 6.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Bupivacaine	Other / unclassified	266 mg	Other
Subject	Morphine	Other / unclassified	50 ug	Intrathecal
Subject	Morphine	Other / unclassified	150 ug	Intrathecal

Indications

No indication recorded.