drugset / Trial / NCT00910208

Safety and Efficacy of Patient Controlled Analgesia in the Emergency Department

Completed 211 enrolled Albert Einstein College of Medicine Jacobi Medical Center · collab National Institute of Nursing Research (NINR) · collab National Institutes of Health (NIH) · collab

RandomizedParallel-groupOpen-labelTreatment

Summary

The aims of this study are to assess efficacy and safety of patient-controlled analgesia (PCA) when applied to the Emergency Department setting and to compare the efficacy and safety of two PCA dosing regimens.

Timeline

Start: 2009-04
Primary completion: 2010-06
Completion: 2010-06

Outcome

Mixed primary results

registry analysis (superiority test); PCA 1 mg Demand Dose vs PCA 1.5 mg Demand Dose vs Non-PCA Comparison Group; p = 0.82; ANOVA NCT00910208 ↗

registry analysis (superiority test); PCA 1 mg Demand Dose vs PCA 1.5 mg Demand Dose vs Non-PCA Comparison Group; p = 0.47; Chi-squared NCT00910208 ↗

registry analysis (superiority test); PCA 1 mg Demand Dose vs PCA 1.5 mg Demand Dose vs Non-PCA Comparison Group; p = 0.06; ANOVA NCT00910208 ↗

registry analysis (superiority test); PCA 1 mg Demand Dose vs PCA 1.5 mg Demand Dose vs Non-PCA Comparison Group; p = 0.033; Chi-squared NCT00910208 ↗

registry COUNT_OF_PARTICIPANTS PCA 1.5 mg Demand Dose: A lot of relief: 34 Participants NCT00910208 ↗

registry COUNT_OF_PARTICIPANTS Non-PCA Comparison Group: A lot of relief: 16 Participants NCT00910208 ↗

Publications

Birnbaum A, Schechter C, Tufaro V, Touger R, Gallagher EJ, Bijur P. Efficacy of patient-controlled analgesia for patients with acute abdominal pain in the emergency department: a randomized trial. Acad Emerg Med. 2012 Apr;19(4):370-7. doi: 10.1111/j.1553-2712.2012.01322.x.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Morphine	Other / unclassified	1 mg	Intravenous
Subject	Morphine	Other / unclassified	1.5 mg	Intravenous

Indications

No indication recorded.