drugset / Trial / NCT00644319

Ibuprofen or Morphine in Treating Pain in Patients Undergoing Pleurodesis for Malignant Pleural Effusion

NCT00644319

Phase 2 Unknown 320 enrolled Oxford University Hospitals NHS Trust
RandomizedSupportive care

Summary

RATIONALE: Morphine and ibuprofen help lessen pain caused by pleurodesis. It is not yet known whether one drug is more effective than the other in lessening pleurodesis-related pain or whether the size of the chest drain tube affects pain. PURPOSE: This randomized clinical trial is studying ibuprofen to see how well it works compared with morphine in treating pain in patients undergoing pleurodesis for malignant pleural effusion.

Timeline

Start
2007-03
Primary completion
2009-09
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Ibuprofen Small molecule Oral
Subject Morphine Other / unclassified Oral